GB2181542A - Bacteriophages as recognition and identification agents - Google Patents
Bacteriophages as recognition and identification agentsInfo
- Publication number
- GB2181542A GB2181542A GB08527324A GB8527324A GB2181542A GB 2181542 A GB2181542 A GB 2181542A GB 08527324 A GB08527324 A GB 08527324A GB 8527324 A GB8527324 A GB 8527324A GB 2181542 A GB2181542 A GB 2181542A
- Authority
- GB
- United Kingdom
- Prior art keywords
- bacteriophages
- recognition
- identification
- antibodies
- agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
- G01N33/586—Liposomes, microcapsules or cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Mycology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Bacteriophages are employed as agents for recognition and identification of molecules and cellular materials, using their ability to recognize their bacterial host, by coating them with antibodies or by selecting them to perform in a manner analogous to antibodies. Visibility for identification is effected by incorporating a fluorescent agent, a radioisotope, a metal, an enzyme, or other staining material. The method of this invention may be utilized in selected clinical procedures, and is adaptable to use in an assay kit.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US59113684A | 1984-03-19 | 1984-03-19 | |
PCT/US1985/000438 WO1985004189A1 (en) | 1984-03-19 | 1985-03-15 | Bacteriophages as recognition and identification agents |
Publications (2)
Publication Number | Publication Date |
---|---|
GB8527324D0 GB8527324D0 (en) | 1985-12-11 |
GB2181542A true GB2181542A (en) | 1987-04-23 |
Family
ID=24365204
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB08527324A Withdrawn GB2181542A (en) | 1984-03-19 | 1985-03-15 | Bacteriophages as recognition and identification agents |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0175761A4 (en) |
JP (1) | JPS61501489A (en) |
DE (1) | DE3590116T1 (en) |
GB (1) | GB2181542A (en) |
NL (1) | NL8520062A (en) |
SE (1) | SE8505458D0 (en) |
WO (1) | WO1985004189A1 (en) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4746604A (en) * | 1985-05-24 | 1988-05-24 | Enzo Biochem, Inc. | Specific binding assays utilizing a viable cell as a label |
CA1313111C (en) * | 1986-12-01 | 1993-01-26 | William J. Hubbard | Method of identifying unknown organisms |
EP0439354A3 (en) * | 1990-01-24 | 1992-06-17 | Amoco Corporation | Signal generating moiety and method for use |
GB9326277D0 (en) * | 1993-12-23 | 1994-02-23 | Marconi Gec Ltd | Labelling |
JP3270722B2 (en) * | 1996-09-27 | 2002-04-02 | オルガノ株式会社 | Bacteria detection method and detection device |
IT1291913B1 (en) | 1997-05-22 | 1999-01-21 | Angeletti P Ist Richerche Bio | METHOD INVOLVING THE USE OF BACTERIOPHAGES FOR THE DETECTION OF THE PRESENCE OF MOLECULES OF INTEREST IN BIOLOGICAL SAMPLES |
CA2333463A1 (en) * | 1998-06-04 | 1999-12-09 | Microsens Biophage Limited | Analytical method using multiple virus labelling |
EP1031630B1 (en) * | 1999-02-22 | 2004-10-20 | Matsushita Electric Industrial Co., Ltd. | Method for detecting bacteria |
DK1198713T3 (en) * | 1999-07-30 | 2006-05-01 | Profos Ag | Detection and identification of bacterial strains |
US8216780B2 (en) | 2002-04-12 | 2012-07-10 | Microphage (Tm) Incorporated | Method for enhanced sensitivity in bacteriophage-based diagnostic assays |
ES2346424T3 (en) | 2002-04-12 | 2010-10-15 | Colorado School Of Mines | PROCEDURE FOR DETECTION OF LOW CONCENTRATIONS OF A DIANA BACTERIA THAT USES PHAGOS TO INFECT BACTERIAL CELLS DIANA. |
WO2006105504A1 (en) * | 2005-03-31 | 2006-10-05 | Microphage Incorporated | Apparatus and method for detecting microorganisms using flagged bacteriophage |
AU2006292496B2 (en) * | 2005-09-15 | 2011-04-14 | Microphage Incorporated | Method and apparatus for identification of microorganisms using bacteriophage |
US8455186B2 (en) | 2007-06-15 | 2013-06-04 | MicroPhage™ Incorporated | Method of detection of microorganisms with enhanced bacteriophage amplification |
US8697434B2 (en) | 2008-01-11 | 2014-04-15 | Colorado School Of Mines | Detection of phage amplification by SERS nanoparticles |
US9441204B2 (en) | 2008-04-03 | 2016-09-13 | Colorado School Of Mines | Compositions and methods for detecting Yersinia pestis bacteria |
FR2940318B1 (en) * | 2008-12-22 | 2011-05-13 | Centre Nat Rech Scient | NEW BIOTRACTORS AND THEIR USES FOR THE CONTROL OF FILTRATION FACILITIES |
WO2017023721A1 (en) * | 2015-07-31 | 2017-02-09 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Detection of bacteria using bacteriophage |
Citations (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3094466A (en) * | 1959-07-15 | 1963-06-18 | Warner Lambert Pharmaceutical | Preparation for typing of staphylococci and process therefor |
US3553310A (en) * | 1967-12-28 | 1971-01-05 | Miles Lab | Immunologically reactive particles |
US3562384A (en) * | 1960-11-08 | 1971-02-09 | Miles Lab | Immunological indicator and test system |
US3717705A (en) * | 1969-01-16 | 1973-02-20 | M Sela | Protein-bacteriophage conjugates |
US4104126A (en) * | 1976-01-29 | 1978-08-01 | Nichols Institute Of Endocrinology, Inc. | Non-isotopic substrate assay employing bacteriolysis products |
US4105598A (en) * | 1975-11-24 | 1978-08-08 | California Institute Of Technology | Cell specific, variable density, polymer microspheres |
US4189466A (en) * | 1975-09-19 | 1980-02-19 | Technical Research Affiliates, Inc. | Detection of rheumatoid factor by antibody sensitized microbial particles |
US4223005A (en) * | 1979-02-15 | 1980-09-16 | University Of Illinois Foundation | Antibody coated bacteria |
US4282315A (en) * | 1979-09-13 | 1981-08-04 | Corning Glass Works | Preparation of enriched whole virus radioligand |
US4298689A (en) * | 1978-09-25 | 1981-11-03 | Research Corporation | Gonorrhea diagnostic test |
US4347311A (en) * | 1979-07-28 | 1982-08-31 | MEDAC Gesellschaft fur Klinishce Spezialpraparate mbH | Enzyme immunoassay for determining antigen specific antibodies and test kit for carrying out this assay |
US4474877A (en) * | 1980-09-19 | 1984-10-02 | Research And Education Institute, Inc. Harbor - Ucla Medical Center | Process for detection and measurement of viral specific immunoglobulins and article of manufacture therefor |
US4508829A (en) * | 1981-09-16 | 1985-04-02 | Teva Pharmaceutical Industries Ltd. | Method and kit for pregnancy detection |
US4511662A (en) * | 1982-06-18 | 1985-04-16 | Bio-Rad Laboratories, Inc. | Simultaneous assay for T and B lymphocyte populations and subpopulations |
-
1985
- 1985-03-15 GB GB08527324A patent/GB2181542A/en not_active Withdrawn
- 1985-03-15 EP EP19850901766 patent/EP0175761A4/en not_active Withdrawn
- 1985-03-15 NL NL8520062A patent/NL8520062A/en unknown
- 1985-03-15 JP JP50141285A patent/JPS61501489A/en active Pending
- 1985-03-15 DE DE19853590116 patent/DE3590116T1/de not_active Withdrawn
- 1985-03-15 WO PCT/US1985/000438 patent/WO1985004189A1/en not_active Application Discontinuation
- 1985-11-19 SE SE8505458A patent/SE8505458D0/en not_active Application Discontinuation
Patent Citations (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3094466A (en) * | 1959-07-15 | 1963-06-18 | Warner Lambert Pharmaceutical | Preparation for typing of staphylococci and process therefor |
US3562384A (en) * | 1960-11-08 | 1971-02-09 | Miles Lab | Immunological indicator and test system |
US3553310A (en) * | 1967-12-28 | 1971-01-05 | Miles Lab | Immunologically reactive particles |
US3717705A (en) * | 1969-01-16 | 1973-02-20 | M Sela | Protein-bacteriophage conjugates |
US4189466A (en) * | 1975-09-19 | 1980-02-19 | Technical Research Affiliates, Inc. | Detection of rheumatoid factor by antibody sensitized microbial particles |
US4105598A (en) * | 1975-11-24 | 1978-08-08 | California Institute Of Technology | Cell specific, variable density, polymer microspheres |
US4104126A (en) * | 1976-01-29 | 1978-08-01 | Nichols Institute Of Endocrinology, Inc. | Non-isotopic substrate assay employing bacteriolysis products |
US4298689A (en) * | 1978-09-25 | 1981-11-03 | Research Corporation | Gonorrhea diagnostic test |
US4223005A (en) * | 1979-02-15 | 1980-09-16 | University Of Illinois Foundation | Antibody coated bacteria |
US4347311A (en) * | 1979-07-28 | 1982-08-31 | MEDAC Gesellschaft fur Klinishce Spezialpraparate mbH | Enzyme immunoassay for determining antigen specific antibodies and test kit for carrying out this assay |
US4282315A (en) * | 1979-09-13 | 1981-08-04 | Corning Glass Works | Preparation of enriched whole virus radioligand |
US4474877A (en) * | 1980-09-19 | 1984-10-02 | Research And Education Institute, Inc. Harbor - Ucla Medical Center | Process for detection and measurement of viral specific immunoglobulins and article of manufacture therefor |
US4508829A (en) * | 1981-09-16 | 1985-04-02 | Teva Pharmaceutical Industries Ltd. | Method and kit for pregnancy detection |
US4511662A (en) * | 1982-06-18 | 1985-04-16 | Bio-Rad Laboratories, Inc. | Simultaneous assay for T and B lymphocyte populations and subpopulations |
Non-Patent Citations (1)
Title |
---|
N, MOLECULAR IMMUNOLOGY, VOLUME 17, ISSUED 1980, PAGES 395-401. * |
Also Published As
Publication number | Publication date |
---|---|
GB8527324D0 (en) | 1985-12-11 |
EP0175761A1 (en) | 1986-04-02 |
NL8520062A (en) | 1986-02-03 |
JPS61501489A (en) | 1986-07-24 |
WO1985004189A1 (en) | 1985-09-26 |
SE8505458L (en) | 1985-11-19 |
EP0175761A4 (en) | 1986-09-24 |
DE3590116T1 (en) | 1987-02-19 |
SE8505458D0 (en) | 1985-11-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
WAP | Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1) |