GB2106116B - Steroidal(16a,17-b)cyclohexene and naphthaleno-21-als and acetals - Google Patents

Steroidal(16a,17-b)cyclohexene and naphthaleno-21-als and acetals

Info

Publication number
GB2106116B
GB2106116B GB08208035A GB8208035A GB2106116B GB 2106116 B GB2106116 B GB 2106116B GB 08208035 A GB08208035 A GB 08208035A GB 8208035 A GB8208035 A GB 8208035A GB 2106116 B GB2106116 B GB 2106116B
Authority
GB
United Kingdom
Prior art keywords
naphthaleno
acetals
cyclohexene
steroidal
als
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08208035A
Other versions
GB2106116A (en
Inventor
Ravi Kannadikovilakom Varma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/919,006 external-priority patent/US4160772A/en
Priority claimed from US05/919,020 external-priority patent/US4164504A/en
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of GB2106116A publication Critical patent/GB2106116A/en
Application granted granted Critical
Publication of GB2106116B publication Critical patent/GB2106116B/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J53/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002Carbocyclic rings fused
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J13/00Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB08208035A 1978-06-26 1982-03-19 Steroidal(16a,17-b)cyclohexene and naphthaleno-21-als and acetals Expired GB2106116B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/919,006 US4160772A (en) 1978-06-26 1978-06-26 Steroidal[16α,17-d]cyclohexene-21-carboxylic acid esters
US05/919,020 US4164504A (en) 1978-06-26 1978-06-26 Steroidal[16α,17-b]naphthaleno-21-carboxylic acid esters

Publications (2)

Publication Number Publication Date
GB2106116A GB2106116A (en) 1983-04-07
GB2106116B true GB2106116B (en) 1983-08-03

Family

ID=27129763

Family Applications (2)

Application Number Title Priority Date Filing Date
GB7918394A Expired GB2023608B (en) 1978-06-26 1979-05-25 Steroidal cyclohexene and naphthalene-21-oic acids and esters
GB08208035A Expired GB2106116B (en) 1978-06-26 1982-03-19 Steroidal(16a,17-b)cyclohexene and naphthaleno-21-als and acetals

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB7918394A Expired GB2023608B (en) 1978-06-26 1979-05-25 Steroidal cyclohexene and naphthalene-21-oic acids and esters

Country Status (24)

Country Link
AU (1) AU524173B2 (en)
CA (1) CA1142916A (en)
CH (1) CH642087A5 (en)
CS (2) CS208160B2 (en)
DD (1) DD144550A5 (en)
DE (1) DE2925552A1 (en)
DK (1) DK267079A (en)
ES (2) ES481875A1 (en)
FI (1) FI791934A (en)
FR (1) FR2429796A1 (en)
GB (2) GB2023608B (en)
GR (1) GR72244B (en)
HU (1) HU180089B (en)
IE (1) IE49178B1 (en)
IL (1) IL57622A (en)
IT (1) IT1162746B (en)
LU (1) LU81420A1 (en)
NL (1) NL7904510A (en)
NO (1) NO792118L (en)
NZ (1) NZ190510A (en)
PL (1) PL216614A1 (en)
PT (1) PT69818A (en)
SE (1) SE7905568L (en)
SU (2) SU946404A3 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4391755A (en) * 1982-01-18 1983-07-05 E. R. Squibb & Sons, Inc. Steroid monohydrates, formulations containing same and method

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2924307A (en) * 1956-09-27 1960-02-09 Gen Motors Corp Brake adjusting device
US3944584A (en) * 1975-02-03 1976-03-16 E. R. Squibb & Sons, Inc. Steroidal (16α,17-d)cyclohexenes

Also Published As

Publication number Publication date
CH642087A5 (en) 1984-03-30
DK267079A (en) 1979-12-27
GB2023608A (en) 1980-01-03
IE791181L (en) 1979-12-26
PT69818A (en) 1979-07-01
GB2106116A (en) 1983-04-07
ES481866A1 (en) 1980-06-16
IT1162746B (en) 1987-04-01
IL57622A (en) 1983-02-23
IT7923840A0 (en) 1979-06-25
IE49178B1 (en) 1985-08-21
PL216614A1 (en) 1980-03-24
CA1142916A (en) 1983-03-15
HU180089B (en) 1983-01-28
SU1055334A3 (en) 1983-11-15
CS208160B2 (en) 1981-08-31
NL7904510A (en) 1979-12-28
ES481875A1 (en) 1980-07-01
CS208159B2 (en) 1981-08-31
FR2429796A1 (en) 1980-01-25
DD144550A5 (en) 1980-10-22
SU946404A3 (en) 1982-07-23
FI791934A (en) 1979-12-27
LU81420A1 (en) 1979-09-12
AU4748179A (en) 1980-01-03
DE2925552A1 (en) 1980-01-17
IL57622A0 (en) 1979-10-31
NO792118L (en) 1979-12-28
GR72244B (en) 1983-10-04
NZ190510A (en) 1982-03-09
GB2023608B (en) 1983-04-27
SE7905568L (en) 1979-12-27
AU524173B2 (en) 1982-09-02
FR2429796B1 (en) 1983-01-07

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee