GB2054593A - 6-Alkyl-7-phenyl-1,6-naphthyridine- 5(6H)-one derivatives - Google Patents
6-Alkyl-7-phenyl-1,6-naphthyridine- 5(6H)-one derivatives Download PDFInfo
- Publication number
- GB2054593A GB2054593A GB8023935A GB8023935A GB2054593A GB 2054593 A GB2054593 A GB 2054593A GB 8023935 A GB8023935 A GB 8023935A GB 8023935 A GB8023935 A GB 8023935A GB 2054593 A GB2054593 A GB 2054593A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compound
- formula
- hydrogen
- halogen
- 3alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6072979A | 1979-07-25 | 1979-07-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB2054593A true GB2054593A (en) | 1981-02-18 |
Family
ID=22031390
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB8023935A Withdrawn GB2054593A (en) | 1979-07-25 | 1980-07-22 | 6-Alkyl-7-phenyl-1,6-naphthyridine- 5(6H)-one derivatives |
Country Status (15)
Country | Link |
---|---|
JP (1) | JPS5620588A (da) |
AU (1) | AU6072080A (da) |
BE (1) | BE884407A (da) |
DE (1) | DE3027619A1 (da) |
DK (1) | DK318280A (da) |
ES (1) | ES8105998A1 (da) |
FI (1) | FI802318A (da) |
FR (1) | FR2462438A1 (da) |
GB (1) | GB2054593A (da) |
IL (1) | IL60672A0 (da) |
IT (1) | IT8049312A0 (da) |
NL (1) | NL8004236A (da) |
PT (1) | PT71592B (da) |
SE (1) | SE8005303L (da) |
ZA (1) | ZA804524B (da) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5466697A (en) * | 1994-07-13 | 1995-11-14 | Syntex (U.S.A.) Inc. | 8-phenyl-1,6-naphthyridin-5-ones |
FR2751969A1 (fr) * | 1996-08-01 | 1998-02-06 | Centre Nat Rech Scient | Composes activateurs du canal cftr, et compositions pharmaceutiques les contenant |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3502831A1 (de) * | 1985-01-29 | 1986-07-31 | Gödecke AG, 1000 Berlin | 1,6-naphthyridinon-derivate, verfahren zu deren herstellung und deren verwendung |
EP2313406B1 (de) * | 2008-08-05 | 2015-02-25 | Boehringer Ingelheim International GmbH | 4-dimethylaminophenyl-substituierte napththyridine und ihre verwendung als arzneimittel |
CA2786245A1 (en) | 2010-01-29 | 2011-08-04 | Boehringer Ingelheim International Gmbh | Substituted naphthyridines and their use as syk kinase inhibitors |
EP2736886B1 (en) | 2011-07-26 | 2016-09-14 | Boehringer Ingelheim International GmbH | Substituted quinolines and their use as medicaments |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2702600A1 (de) * | 1977-01-22 | 1978-07-27 | Thomae Gmbh Dr K | Neue aminoalkoxyphenyl-derivate |
-
1980
- 1980-07-21 DE DE3027619A patent/DE3027619A1/de not_active Withdrawn
- 1980-07-22 SE SE8005303A patent/SE8005303L/xx unknown
- 1980-07-22 BE BE1/9900A patent/BE884407A/fr unknown
- 1980-07-22 GB GB8023935A patent/GB2054593A/en not_active Withdrawn
- 1980-07-23 ES ES493639A patent/ES8105998A1/es not_active Expired
- 1980-07-23 PT PT71592A patent/PT71592B/pt unknown
- 1980-07-23 NL NL8004236A patent/NL8004236A/nl not_active Application Discontinuation
- 1980-07-23 AU AU60720/80A patent/AU6072080A/en not_active Abandoned
- 1980-07-23 FI FI802318A patent/FI802318A/fi not_active Application Discontinuation
- 1980-07-23 IL IL60672A patent/IL60672A0/xx unknown
- 1980-07-23 DK DK318280A patent/DK318280A/da unknown
- 1980-07-24 JP JP10063780A patent/JPS5620588A/ja active Pending
- 1980-07-24 IT IT8049312A patent/IT8049312A0/it unknown
- 1980-07-25 ZA ZA00804524A patent/ZA804524B/xx unknown
- 1980-07-25 FR FR8016438A patent/FR2462438A1/fr not_active Withdrawn
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5466697A (en) * | 1994-07-13 | 1995-11-14 | Syntex (U.S.A.) Inc. | 8-phenyl-1,6-naphthyridin-5-ones |
FR2751969A1 (fr) * | 1996-08-01 | 1998-02-06 | Centre Nat Rech Scient | Composes activateurs du canal cftr, et compositions pharmaceutiques les contenant |
US6630482B1 (en) | 1996-08-01 | 2003-10-07 | Centre National De La Recherche Scientifique | CFTR channel activator compounds and pharmaceutical compositions containing same |
Also Published As
Publication number | Publication date |
---|---|
ZA804524B (en) | 1982-03-31 |
DK318280A (da) | 1981-01-26 |
ES493639A0 (es) | 1981-07-01 |
PT71592A (en) | 1980-08-01 |
SE8005303L (sv) | 1981-01-26 |
DE3027619A1 (de) | 1981-02-19 |
PT71592B (en) | 1981-08-11 |
BE884407A (fr) | 1981-01-22 |
AU6072080A (en) | 1981-01-29 |
NL8004236A (nl) | 1981-01-27 |
FI802318A (fi) | 1981-01-26 |
IT8049312A0 (it) | 1980-07-24 |
JPS5620588A (en) | 1981-02-26 |
IL60672A0 (en) | 1980-09-16 |
FR2462438A1 (fr) | 1981-02-13 |
ES8105998A1 (es) | 1981-07-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
WAP | Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1) |