GB1072710A - í¸-pyrroline derivatives - Google Patents
í¸-pyrroline derivativesInfo
- Publication number
- GB1072710A GB1072710A GB3287064A GB3287064A GB1072710A GB 1072710 A GB1072710 A GB 1072710A GB 3287064 A GB3287064 A GB 3287064A GB 3287064 A GB3287064 A GB 3287064A GB 1072710 A GB1072710 A GB 1072710A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydrogen
- pyrroline
- carboxylic acid
- aralkyl
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Abstract
Novel D 3-pyrroline derivatives of general formulae <FORM:1072710/C2/1> wherein A represents <FORM:1072710/C2/2> <FORM:1072710/C2/3> in which R1, R2 and R3 are hydrogen or halogen, or lower alkyl, aryl, aralkyl, lower alkanoyl halogenomethyl, nitro, amino, lower alkylthio, lower alkoxy, carbo lower alkoxy, mono- or di-lower alkylamino or hydroxy groups, and, when A is a phenyl group at least one of the groups R1, R2, R3 is different from hydrogen; R4 is a lower alkyl, lower alkenyl or aralkyl group or a lower dialkylamino group, and salts thereof and their preparation by reacting D 3 - pyrroline - 2 - carboxylic acid with the acid halide or reactive ester of the required carboxylic acid wherein R1, R2, R3 and -R4 are as defined above. Pharmaceutical compositions having anti-flammatory and anti-pyretic activity contain a compound of the first general formula above or a salt thereof derived from an inorganic or organic base, as the active ingredient.
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB3287064A GB1072710A (en) | 1964-08-12 | 1964-08-12 | í¸-pyrroline derivatives |
FR27853A FR1462258A (en) | 1964-08-12 | 1965-08-10 | Delta3-pyrroline derivatives and their manufacturing process |
DE19651620164 DE1620164A1 (en) | 1964-08-12 | 1965-08-10 | Process for the production of delta3-pyrroline derivatives |
CH1134465A CH475980A (en) | 1964-08-12 | 1965-08-12 | Process for the preparation of 3-pyrroline derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB3287064A GB1072710A (en) | 1964-08-12 | 1964-08-12 | í¸-pyrroline derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1072710A true GB1072710A (en) | 1967-06-21 |
Family
ID=10345254
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB3287064A Expired GB1072710A (en) | 1964-08-12 | 1964-08-12 | í¸-pyrroline derivatives |
Country Status (3)
Country | Link |
---|---|
CH (1) | CH475980A (en) |
DE (1) | DE1620164A1 (en) |
GB (1) | GB1072710A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6124472A (en) * | 1996-07-26 | 2000-09-26 | Basf Aktiengesellschaft | Process for preparing 3-pyrroline-2-carboxylic acid derivatives |
-
1964
- 1964-08-12 GB GB3287064A patent/GB1072710A/en not_active Expired
-
1965
- 1965-08-10 DE DE19651620164 patent/DE1620164A1/en active Pending
- 1965-08-12 CH CH1134465A patent/CH475980A/en not_active IP Right Cessation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6124472A (en) * | 1996-07-26 | 2000-09-26 | Basf Aktiengesellschaft | Process for preparing 3-pyrroline-2-carboxylic acid derivatives |
Also Published As
Publication number | Publication date |
---|---|
CH475980A (en) | 1969-07-31 |
DE1620164A1 (en) | 1970-02-12 |
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