SE8000699L - NEW CHINAZOLINE DERIVATIVES ALSO SET FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM - Google Patents

NEW CHINAZOLINE DERIVATIVES ALSO SET FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM

Info

Publication number
SE8000699L
SE8000699L SE8000699A SE8000699A SE8000699L SE 8000699 L SE8000699 L SE 8000699L SE 8000699 A SE8000699 A SE 8000699A SE 8000699 A SE8000699 A SE 8000699A SE 8000699 L SE8000699 L SE 8000699L
Authority
SE
Sweden
Prior art keywords
alkyl
preparation
new
pharmaceutical preparations
preparations containing
Prior art date
Application number
SE8000699A
Other languages
Swedish (sv)
Inventor
S F Campbell
J C Danilewicz
C W Greengrass
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of SE8000699L publication Critical patent/SE8000699L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/46Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Title: "Quinazoline Antihypertensives" Quinazoline antihypertensives of the formula: --- (I) and their pharmaceutically acceptable acid addition salts, wherein R is C1-C4 alXyl, benzyl or (C3-C6 cycloalkyl)methyl, R is C1-C4 alkyl, X is -CH2CH2- substltuted by a phenyl group and optianally by 1 or 2 methyl groups; and R2 is hydrogen, C1-C4 alkyl, or phenyl optionally substituted by 1 or 2 substltuents selected from C1-C4 alkyl, C1-C4 alkoxy, halogen, CF3, -CONR3R4 and -SO2NR3R4 wherein R3 and R4 each represent hydrogen or Cl-C4 alkyl; and processes for preparing the compounds of the formula (I); and pharmaceutical compositions containing them.
SE8000699A 1979-01-31 1980-01-29 NEW CHINAZOLINE DERIVATIVES ALSO SET FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM SE8000699L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7903398 1979-01-31

Publications (1)

Publication Number Publication Date
SE8000699L true SE8000699L (en) 1980-08-01

Family

ID=10502852

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8000699A SE8000699L (en) 1979-01-31 1980-01-29 NEW CHINAZOLINE DERIVATIVES ALSO SET FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM

Country Status (28)

Country Link
JP (1) JPS55104278A (en)
AR (1) AR222208A1 (en)
AT (1) AT373595B (en)
BE (1) BE881448A (en)
CA (1) CA1131636A (en)
CS (1) CS231970B2 (en)
DD (1) DD148720A5 (en)
DE (1) DE3003323A1 (en)
DK (1) DK540879A (en)
ES (1) ES488129A0 (en)
FI (1) FI63936C (en)
FR (1) FR2447919A1 (en)
GR (1) GR73626B (en)
HU (1) HU184233B (en)
IE (1) IE800178L (en)
IL (1) IL59252A (en)
IT (1) IT1149902B (en)
LU (1) LU82115A1 (en)
NL (1) NL8000571A (en)
NO (1) NO800230L (en)
NZ (1) NZ192744A (en)
PH (1) PH15436A (en)
PL (1) PL121890B1 (en)
PT (1) PT70749A (en)
SE (1) SE8000699L (en)
SU (1) SU895291A3 (en)
YU (1) YU22980A (en)
ZA (1) ZA80557B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2483920A1 (en) * 1980-06-09 1981-12-11 Synthelabo Antihypertensive piperidino quinazoline(s) - prepd. from benzyloxy piperidine and a 2:halo-4:amino 6,7-di:methoxy quinazoline
ES515338A0 (en) * 1981-09-09 1983-11-01 Orion Yhtymae Oy "METHOD FOR THE PREPARATION OF SUBSTITUTED PIPERIDINYLQUINAZOLIDINES".
US5280032A (en) * 1989-02-14 1994-01-18 Toyama Chemical Co., Ltd. 1,2-ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same
WO2013070852A2 (en) * 2011-11-08 2013-05-16 Emory University Compounds and compositions used to epigenetically transform cells and methods related thereto

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1088068A (en) * 1977-11-16 1980-10-21 Simon F. Campbell Piperidino-quinazolines
GB2021108B (en) * 1978-05-18 1982-07-21 Pfizer Ltd 6,7 - di - 4 - amino - 2 - quinazolines

Also Published As

Publication number Publication date
CS231970B2 (en) 1985-01-16
AT373595B (en) 1984-02-10
CS60780A2 (en) 1984-01-16
SU895291A3 (en) 1981-12-30
PL221683A1 (en) 1980-12-01
ZA80557B (en) 1981-08-26
IL59252A (en) 1983-11-30
ES8101583A1 (en) 1980-12-16
FR2447919B1 (en) 1983-02-11
YU22980A (en) 1983-02-28
FI63936B (en) 1983-05-31
HU184233B (en) 1984-07-30
JPS55104278A (en) 1980-08-09
IT8019537A0 (en) 1980-01-29
AU5502480A (en) 1980-08-07
IL59252A0 (en) 1980-05-30
NL8000571A (en) 1980-08-04
DE3003323A1 (en) 1980-08-14
AR222208A1 (en) 1981-04-30
LU82115A1 (en) 1980-04-23
CA1131636A (en) 1982-09-14
PT70749A (en) 1980-02-01
DK540879A (en) 1980-08-01
ATA46980A (en) 1983-06-15
FR2447919A1 (en) 1980-08-29
NO800230L (en) 1980-08-01
PL121890B1 (en) 1982-06-30
ES488129A0 (en) 1980-12-16
JPS5728711B2 (en) 1982-06-18
NZ192744A (en) 1984-03-30
IT1149902B (en) 1986-12-10
DD148720A5 (en) 1981-06-10
GR73626B (en) 1984-03-26
PH15436A (en) 1983-01-18
FI800252A (en) 1980-08-01
FI63936C (en) 1983-09-12
BE881448A (en) 1980-07-30
IE800178L (en) 1980-07-31

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