GB1058542A - Nortropane derivatives and the preparation thereof - Google Patents

Nortropane derivatives and the preparation thereof

Info

Publication number
GB1058542A
GB1058542A GB853364A GB853364A GB1058542A GB 1058542 A GB1058542 A GB 1058542A GB 853364 A GB853364 A GB 853364A GB 853364 A GB853364 A GB 853364A GB 1058542 A GB1058542 A GB 1058542A
Authority
GB
United Kingdom
Prior art keywords
formula
alkylene
aryl
atom
product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB853364A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ROBERT PFLEGER CHEM FAB DR
Original Assignee
ROBERT PFLEGER CHEM FAB DR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ROBERT PFLEGER CHEM FAB DR filed Critical ROBERT PFLEGER CHEM FAB DR
Publication of GB1058542A publication Critical patent/GB1058542A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
GB853364A 1963-03-05 1964-02-28 Nortropane derivatives and the preparation thereof Expired GB1058542A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEP31263A DE1194422B (de) 1963-03-05 1963-03-05 Verfahren zur Herstellung von Azoniaspironortropanderivaten

Publications (1)

Publication Number Publication Date
GB1058542A true GB1058542A (en) 1967-02-15

Family

ID=7372224

Family Applications (1)

Application Number Title Priority Date Filing Date
GB853364A Expired GB1058542A (en) 1963-03-05 1964-02-28 Nortropane derivatives and the preparation thereof

Country Status (6)

Country Link
AT (1) AT255662B (xx)
BE (1) BE644401A (xx)
CH (1) CH440308A (xx)
DE (1) DE1194422B (xx)
GB (1) GB1058542A (xx)
NL (1) NL129436C (xx)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2184726A (en) * 1985-12-27 1987-07-01 Madaus & Co Dr Azoniaspironortropanol esters, processes for the preparation thereof and pharmaceutical compositions containing them
US7410978B2 (en) 2003-11-04 2008-08-12 Supernus Pharmaceuticals, Inc. Once daily dosage forms of trospium
US8709476B2 (en) 2003-11-04 2014-04-29 Supernus Pharmaceuticals, Inc. Compositions of quaternary ammonium compounds containing bioavailability enhancers

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3546218A1 (de) * 1985-12-27 1987-07-02 Madaus & Co Dr Azoniaspironortropanolester, verfahren zu deren herstellung und pharmazeutisches mittel
ES2125696T3 (es) 1996-11-27 1999-03-01 Pfleger R Chem Fab Utilizacion del cloruro de tropsio para la produccion de una preparacion farmaceutica para el tratamiento de disfunciones vesicales.
DE59900129D1 (de) 1999-02-20 2001-07-26 Pfleger R Chem Fab Verfahren zum Herstellen von endo-Nortropin unter Verwendung von 8-Benzyl-nortropan-3-on-perchlorat als Zwischenprodukt, sowie letzteres Salz selbst
PT2121679E (pt) 2007-02-23 2015-06-09 K H S Pharma Holding Gmbh Método para a produção de ésteres de azoniaspironortropina

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2184726A (en) * 1985-12-27 1987-07-01 Madaus & Co Dr Azoniaspironortropanol esters, processes for the preparation thereof and pharmaceutical compositions containing them
GB2184726B (en) * 1985-12-27 1990-10-03 Madaus & Co Dr Azoniaspironortropanol esters, processes for the preparation thereof and pharmaceutical compositions containing them
US7410978B2 (en) 2003-11-04 2008-08-12 Supernus Pharmaceuticals, Inc. Once daily dosage forms of trospium
US7759359B2 (en) 2003-11-04 2010-07-20 Supernus Pharmaceuticals, Inc. Method of treating bladder dysfunction with once-a-day trospium salt formulation
US7763635B2 (en) 2003-11-04 2010-07-27 Supermus Pharmaceuticals, Inc. Once daily dosage forms of trospium
US7781448B2 (en) 2003-11-04 2010-08-24 Supernus Pharmaceuticals, Inc. Once daily dosage forms of trospium
US7781449B2 (en) 2003-11-04 2010-08-24 Supernus Pharmaceuticals, Inc. Trospium chloride treatment method
US8709476B2 (en) 2003-11-04 2014-04-29 Supernus Pharmaceuticals, Inc. Compositions of quaternary ammonium compounds containing bioavailability enhancers

Also Published As

Publication number Publication date
BE644401A (xx) 1964-08-27
CH440308A (de) 1967-07-31
AT255662B (de) 1967-07-10
DE1194422B (de) 1965-06-10
NL6402155A (xx) 1964-09-07
NL129436C (xx) 1970-08-17

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