FR3090636B1 - Procédé de synthèse de peptides - Google Patents

Procédé de synthèse de peptides Download PDF

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Publication number
FR3090636B1
FR3090636B1 FR1874091A FR1874091A FR3090636B1 FR 3090636 B1 FR3090636 B1 FR 3090636B1 FR 1874091 A FR1874091 A FR 1874091A FR 1874091 A FR1874091 A FR 1874091A FR 3090636 B1 FR3090636 B1 FR 3090636B1
Authority
FR
France
Prior art keywords
peptide synthesis
synthesis process
anchor molecule
units
chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1874091A
Other languages
English (en)
Other versions
FR3090636A1 (fr
Inventor
Tendoung Jean-Jacques Youte
Audrey Serrre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Strainchem
Original Assignee
Strainchem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR1874091A priority Critical patent/FR3090636B1/fr
Application filed by Strainchem filed Critical Strainchem
Priority to CA3124620A priority patent/CA3124620A1/fr
Priority to CN201980085737.9A priority patent/CN113227115A/zh
Priority to PCT/FR2019/000218 priority patent/WO2020136312A1/fr
Priority to AU2019414977A priority patent/AU2019414977A1/en
Priority to EP19845760.8A priority patent/EP3902819A1/fr
Priority to SG11202106305PA priority patent/SG11202106305PA/en
Priority to US17/413,807 priority patent/US20220024971A1/en
Publication of FR3090636A1 publication Critical patent/FR3090636A1/fr
Application granted granted Critical
Publication of FR3090636B1 publication Critical patent/FR3090636B1/fr
Priority to IL283667A priority patent/IL283667A/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Procédé de synthèse de peptides ou protéines par élongation successive de la deuxième extrémité d’une chaîne peptidique dont la première extrémité est fixée sur une molécule d’ancrage soluble dans un solvant apolaire, caractérisé en ce que ladite molécule d’ancrage comporte une chaîne polyoléfine avec au moins 10 unités de monomères, et de préférence entre 15 et 50 unités.
FR1874091A 2018-12-24 2018-12-24 Procédé de synthèse de peptides Active FR3090636B1 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FR1874091A FR3090636B1 (fr) 2018-12-24 2018-12-24 Procédé de synthèse de peptides
CN201980085737.9A CN113227115A (zh) 2018-12-24 2019-12-23 肽的合成方法
PCT/FR2019/000218 WO2020136312A1 (fr) 2018-12-24 2019-12-23 Procédé de synthèse de peptides
AU2019414977A AU2019414977A1 (en) 2018-12-24 2019-12-23 Method for synthesising peptides
CA3124620A CA3124620A1 (fr) 2018-12-24 2019-12-23 Procede de synthese de peptides
EP19845760.8A EP3902819A1 (fr) 2018-12-24 2019-12-23 Procédé de synthèse de peptides
SG11202106305PA SG11202106305PA (en) 2018-12-24 2019-12-23 Method for synthesizing peptides
US17/413,807 US20220024971A1 (en) 2018-12-24 2019-12-23 Method for synthesizing peptides
IL283667A IL283667A (en) 2018-12-24 2021-06-02 Method for synthesising peptides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1874091A FR3090636B1 (fr) 2018-12-24 2018-12-24 Procédé de synthèse de peptides

Publications (2)

Publication Number Publication Date
FR3090636A1 FR3090636A1 (fr) 2020-06-26
FR3090636B1 true FR3090636B1 (fr) 2021-01-01

Family

ID=67587800

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1874091A Active FR3090636B1 (fr) 2018-12-24 2018-12-24 Procédé de synthèse de peptides

Country Status (9)

Country Link
US (1) US20220024971A1 (fr)
EP (1) EP3902819A1 (fr)
CN (1) CN113227115A (fr)
AU (1) AU2019414977A1 (fr)
CA (1) CA3124620A1 (fr)
FR (1) FR3090636B1 (fr)
IL (1) IL283667A (fr)
SG (1) SG11202106305PA (fr)
WO (1) WO2020136312A1 (fr)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2451915A1 (fr) 1979-03-23 1980-10-17 Clin Midy Nouveau procede de preparation de la somatostatine
FR2633295B1 (fr) * 1988-06-27 1992-03-13 Centre Nat Rech Scient Procede de preparation de polypeptides en phase solide
TWI247012B (en) * 2001-07-19 2006-01-11 Akzo Nobel Nv Process for rapid solution synthesis of peptides
CA2496739A1 (fr) * 2002-08-26 2004-03-04 A & Pep Inc. Procede de synthese de peptides
FR2864830B1 (fr) * 2004-01-06 2006-03-10 Centre Nat Rech Scient Procede de synthese sur support solide de composes peptidiques, notamment de composes peptidiques comportant un residu arginine
AU2007304427A1 (en) * 2006-10-05 2008-04-10 Lonza Ag Method for peptide synthesis
WO2012029794A1 (fr) 2010-08-30 2012-03-08 味の素株式会社 Composé aromatique contenant une ramification spécifique
JP6136934B2 (ja) 2011-12-15 2017-05-31 味の素株式会社 Ｆｍｏｃ基の除去方法

Also Published As

Publication number Publication date
WO2020136312A1 (fr) 2020-07-02
SG11202106305PA (en) 2021-07-29
EP3902819A1 (fr) 2021-11-03
US20220024971A1 (en) 2022-01-27
IL283667A (en) 2021-07-29
CA3124620A1 (fr) 2020-07-02
CN113227115A (zh) 2021-08-06
FR3090636A1 (fr) 2020-06-26
AU2019414977A1 (en) 2021-07-01

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