FR2903984B1 - Derives d'imidazolones substitues, preparation et utilisations - Google Patents
Derives d'imidazolones substitues, preparation et utilisationsInfo
- Publication number
- FR2903984B1 FR2903984B1 FR0606752A FR0606752A FR2903984B1 FR 2903984 B1 FR2903984 B1 FR 2903984B1 FR 0606752 A FR0606752 A FR 0606752A FR 0606752 A FR0606752 A FR 0606752A FR 2903984 B1 FR2903984 B1 FR 2903984B1
- Authority
- FR
- France
- Prior art keywords
- preparation
- imidazolone derivatives
- substituted
- substituted imidazolone
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0606752A FR2903984B1 (fr) | 2006-07-24 | 2006-07-24 | Derives d'imidazolones substitues, preparation et utilisations |
JP2009521318A JP2009544675A (ja) | 2006-07-24 | 2007-07-24 | 置換されたイミダゾロン誘導体、製造方法及び使用 |
EP07823633A EP2049107A2 (fr) | 2006-07-24 | 2007-07-24 | Derives d'imidazolones substitues, preparation et utilisations |
KR1020097003832A KR20090038469A (ko) | 2006-07-24 | 2007-07-24 | 치환된 이미다졸론 유도체, 그 제조 및 용도 |
PCT/FR2007/051716 WO2008012470A2 (fr) | 2006-07-24 | 2007-07-24 | Derives d'imidazolones substitues, preparation et utilisations |
BRPI0715326-0A BRPI0715326A2 (pt) | 2006-07-24 | 2007-07-24 | compostos derivados de imidazolonas polissubstituÍdas, composiÇço farmacÊutica e, uso de pelo menos um composto |
EA200900211A EA200900211A1 (ru) | 2006-07-24 | 2007-07-24 | Замещенные производные имидазолона, их получение и применение |
CA002658625A CA2658625A1 (fr) | 2006-07-24 | 2007-07-24 | Derives d'imidazolones substitues, preparation et utilisations |
AU2007279135A AU2007279135A1 (en) | 2006-07-24 | 2007-07-24 | Substituted imidazolone derivatives, preparation and uses |
US12/309,642 US20100004159A1 (en) | 2006-07-24 | 2007-07-24 | Substituted imidazolone derivatives, preparations and uses |
CNA2007800352070A CN101522192A (zh) | 2006-07-24 | 2007-07-24 | 取代的咪唑啉酮衍生物、制备和用途 |
MX2009000900A MX2009000900A (es) | 2006-07-24 | 2007-07-24 | Derivados de imidazolonas sustituidas, preparacion y usos. |
NZ575011A NZ575011A (en) | 2006-07-24 | 2007-07-24 | Substituted imidazolone derivatives, preparation and uses |
IL196671A IL196671A0 (en) | 2006-07-24 | 2009-01-22 | Substituted imidazolone derivatives, preparation and uses |
NO20090348A NO20090348L (no) | 2006-07-24 | 2009-01-22 | Substituerte imidazolonderivater, sammensetninger og anvendelser av samme, samt fremgangsmater for fremstilling av samme |
ZA200901268A ZA200901268B (en) | 2006-07-24 | 2009-02-23 | Substituted imidazolone derivatives, preparation and uses |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0606752A FR2903984B1 (fr) | 2006-07-24 | 2006-07-24 | Derives d'imidazolones substitues, preparation et utilisations |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2903984A1 FR2903984A1 (fr) | 2008-01-25 |
FR2903984B1 true FR2903984B1 (fr) | 2008-10-03 |
Family
ID=37843186
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0606752A Expired - Fee Related FR2903984B1 (fr) | 2006-07-24 | 2006-07-24 | Derives d'imidazolones substitues, preparation et utilisations |
Country Status (16)
Country | Link |
---|---|
US (1) | US20100004159A1 (fr) |
EP (1) | EP2049107A2 (fr) |
JP (1) | JP2009544675A (fr) |
KR (1) | KR20090038469A (fr) |
CN (1) | CN101522192A (fr) |
AU (1) | AU2007279135A1 (fr) |
BR (1) | BRPI0715326A2 (fr) |
CA (1) | CA2658625A1 (fr) |
EA (1) | EA200900211A1 (fr) |
FR (1) | FR2903984B1 (fr) |
IL (1) | IL196671A0 (fr) |
MX (1) | MX2009000900A (fr) |
NO (1) | NO20090348L (fr) |
NZ (1) | NZ575011A (fr) |
WO (1) | WO2008012470A2 (fr) |
ZA (1) | ZA200901268B (fr) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2025674A1 (fr) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Tetrahydronaphthaline substituée, son procédé de fabrication et son utilisation en tant que médicament |
WO2011107494A1 (fr) | 2010-03-03 | 2011-09-09 | Sanofi | Nouveaux dérivés aromatiques de glycoside, médicaments contenants ces composés, et leur utilisation |
EP2552209A4 (fr) * | 2010-03-26 | 2014-01-22 | Merck Sharp & Dohme | Nouveaux dérivés spiro d'imidazolone au titre d'antagonistes de récepteurs de glucagone, compositions, et méthodes pour leur utilisation |
EP2582709B1 (fr) | 2010-06-18 | 2018-01-24 | Sanofi | Dérivés d'azolopyridin-3-one en tant qu'inhibiteurs de lipases et de phospholipases |
US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
US8633231B2 (en) | 2010-07-13 | 2014-01-21 | Merck Sharp & Dohme Corp. | Substituted imidazolones, compositions containing such compounds and methods of use |
WO2013037390A1 (fr) | 2011-09-12 | 2013-03-21 | Sanofi | Dérivés amides d'acide 6-(4-hydroxyphényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase |
EP2760862B1 (fr) | 2011-09-27 | 2015-10-21 | Sanofi | Dérivés d'amide d'acide 6-(4-hydroxyphényl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique utilisés comme inhibiteurs de kinase |
DK3013796T3 (da) * | 2013-06-27 | 2020-03-16 | Lg Chemical Ltd | Biarylderivater som gpr120-agonister |
JP6617106B2 (ja) | 2013-12-17 | 2019-12-04 | ヤンセン ファーマシューティカ エヌ.ベー. | 癌の治療用のfasn阻害剤として有用なイミダゾリン−5−オン誘導体 |
CN105439946B (zh) * | 2014-08-13 | 2018-02-02 | 益方生物科技(上海)有限公司 | 羧酸化合物及其制备方法和用途 |
CN104177298B (zh) * | 2014-09-18 | 2018-10-02 | 湘潭大学 | 4,4-二取代-4,5-二氢-1h–咪唑-5-酮、衍生物及其合成方法 |
CA2992161A1 (fr) | 2015-07-17 | 2017-01-26 | Institut Pasteur | Agent de stimulation du recepteur 1b de la 5-hydroxytryptamine destine a etre utilise comme promoteur de l'autorenouvellement et/ou de la differenciation des cellules satellites |
JP2018526411A (ja) * | 2015-09-11 | 2018-09-13 | ラクオリア創薬株式会社 | Trpm8拮抗剤としてのイミダゾリノン誘導体 |
KR102375929B1 (ko) | 2016-03-31 | 2022-03-16 | 온크터널 테라퓨틱스, 인코포레이티드. | 인돌린 유사체 및 이의 용도 |
BR112019000706A8 (pt) | 2016-07-15 | 2022-12-06 | Pasteur Institut | Agente de estímulo do receptor 1b de 5-hidroxitriptamina para reparo de pele e/ou cabelo |
CN113121394B (zh) * | 2019-12-30 | 2022-11-08 | 中国药科大学 | 一种苯氧乙酸类衍生物的制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR0214437A (pt) * | 2001-11-30 | 2004-10-13 | Lilly Co Eli | Composto, composição farmacêutica, métodos de modular um receptor ativado por proliferador de peroxissoma, de tratar e de prevenir a diabete melito, e de tratar a sìndrome x, e doenças cardiovasculares em um mamìfero, e, uso de um composto |
US7232828B2 (en) * | 2002-08-10 | 2007-06-19 | Bethesda Pharmaceuticals, Inc. | PPAR Ligands that do not cause fluid retention, edema or congestive heart failure |
WO2004082621A2 (fr) * | 2003-03-15 | 2004-09-30 | Bethesda Pharmaceuticals, Inc. | Nouveaux agonistes ppar, compositions pharmaceutiques et leurs utilisations |
-
2006
- 2006-07-24 FR FR0606752A patent/FR2903984B1/fr not_active Expired - Fee Related
-
2007
- 2007-07-24 US US12/309,642 patent/US20100004159A1/en not_active Abandoned
- 2007-07-24 AU AU2007279135A patent/AU2007279135A1/en not_active Abandoned
- 2007-07-24 KR KR1020097003832A patent/KR20090038469A/ko not_active Application Discontinuation
- 2007-07-24 EP EP07823633A patent/EP2049107A2/fr not_active Withdrawn
- 2007-07-24 WO PCT/FR2007/051716 patent/WO2008012470A2/fr active Application Filing
- 2007-07-24 JP JP2009521318A patent/JP2009544675A/ja active Pending
- 2007-07-24 CA CA002658625A patent/CA2658625A1/fr not_active Abandoned
- 2007-07-24 NZ NZ575011A patent/NZ575011A/en not_active IP Right Cessation
- 2007-07-24 EA EA200900211A patent/EA200900211A1/ru unknown
- 2007-07-24 BR BRPI0715326-0A patent/BRPI0715326A2/pt not_active IP Right Cessation
- 2007-07-24 MX MX2009000900A patent/MX2009000900A/es active IP Right Grant
- 2007-07-24 CN CNA2007800352070A patent/CN101522192A/zh active Pending
-
2009
- 2009-01-22 NO NO20090348A patent/NO20090348L/no not_active Application Discontinuation
- 2009-01-22 IL IL196671A patent/IL196671A0/en unknown
- 2009-02-23 ZA ZA200901268A patent/ZA200901268B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CN101522192A (zh) | 2009-09-02 |
BRPI0715326A2 (pt) | 2013-08-13 |
EA200900211A1 (ru) | 2009-06-30 |
JP2009544675A (ja) | 2009-12-17 |
FR2903984A1 (fr) | 2008-01-25 |
ZA200901268B (en) | 2010-04-28 |
KR20090038469A (ko) | 2009-04-20 |
WO2008012470A2 (fr) | 2008-01-31 |
WO2008012470A3 (fr) | 2008-03-20 |
US20100004159A1 (en) | 2010-01-07 |
NZ575011A (en) | 2011-12-22 |
IL196671A0 (en) | 2009-11-18 |
MX2009000900A (es) | 2009-06-18 |
AU2007279135A1 (en) | 2008-01-31 |
CA2658625A1 (fr) | 2008-01-31 |
NO20090348L (no) | 2009-04-24 |
EP2049107A2 (fr) | 2009-04-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |
Effective date: 20100331 |