FR2858619B1 - Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent - Google Patents

Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent

Info

Publication number
FR2858619B1
FR2858619B1 FR0309754A FR0309754A FR2858619B1 FR 2858619 B1 FR2858619 B1 FR 2858619B1 FR 0309754 A FR0309754 A FR 0309754A FR 0309754 A FR0309754 A FR 0309754A FR 2858619 B1 FR2858619 B1 FR 2858619B1
Authority
FR
France
Prior art keywords
quinoline
methods
pharmaceutical compositions
compositions containing
substituted derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0309754A
Other languages
English (en)
Other versions
FR2858619A1 (fr
Inventor
Antony Bigot
Serge Mignani
Baptiste Ronan
Michel Tabart
Fabrice Viviani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Priority to FR0309754A priority Critical patent/FR2858619B1/fr
Priority to JP2006522379A priority patent/JP2007501777A/ja
Priority to CA002535020A priority patent/CA2535020A1/fr
Priority to PCT/FR2004/002090 priority patent/WO2005016916A2/fr
Priority to EP04786264A priority patent/EP1654252A2/fr
Priority to US10/913,222 priority patent/US7348434B2/en
Publication of FR2858619A1 publication Critical patent/FR2858619A1/fr
Application granted granted Critical
Publication of FR2858619B1 publication Critical patent/FR2858619B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FR0309754A 2003-08-08 2003-08-08 Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent Expired - Fee Related FR2858619B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR0309754A FR2858619B1 (fr) 2003-08-08 2003-08-08 Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
JP2006522379A JP2007501777A (ja) 2003-08-08 2004-08-05 ４−置換キノリン誘導体、それらの製造方法及び中間体並びにそれらを含有する製薬組成物
CA002535020A CA2535020A1 (fr) 2003-08-08 2004-08-05 Quinolines substituees comme antimicrobiens
PCT/FR2004/002090 WO2005016916A2 (fr) 2003-08-08 2004-08-05 Quinolines substituées comme antimicrobiens
EP04786264A EP1654252A2 (fr) 2003-08-08 2004-08-05 Quinolines substituees comme antimicrobiens
US10/913,222 US7348434B2 (en) 2003-08-08 2004-08-06 4-substituted quinoline derivatives, method and intermediates for their preparation and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0309754A FR2858619B1 (fr) 2003-08-08 2003-08-08 Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
FR2858619A1 FR2858619A1 (fr) 2005-02-11
FR2858619B1 true FR2858619B1 (fr) 2006-12-22

Family

ID=34073086

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0309754A Expired - Fee Related FR2858619B1 (fr) 2003-08-08 2003-08-08 Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent

Country Status (5)

Country Link
EP (1) EP1654252A2 (fr)
JP (1) JP2007501777A (fr)
CA (1) CA2535020A1 (fr)
FR (1) FR2858619B1 (fr)
WO (1) WO2005016916A2 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE461928T1 (de) 2002-11-05 2010-04-15 Glaxosmithkline Llc Antibakterielle wirkstoffe
US7691850B2 (en) 2004-06-15 2010-04-06 Glaxo Group Limited Antibacterial agents
FR2872164B1 (fr) * 2004-06-29 2006-11-17 Aventis Pharma Sa Derives de quinoleines-4-substituees, leur procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
US7709483B2 (en) 2006-04-06 2010-05-04 Glaxo Group Limited Pyrrolo-quinoxalinone derivatives as antibacterials
EP1992628A1 (fr) 2007-05-18 2008-11-19 Glaxo Group Limited Dérivés et analogues de N-éthylquinolones et N-éthylazaquinolones
EP2080761A1 (fr) 2008-01-18 2009-07-22 Glaxo Group Limited Composés
WO2010043714A1 (fr) 2008-10-17 2010-04-22 Glaxo Group Limited Composés azotés tricycliques utilisés comme agents antibactériens
ES2561631T3 (es) 2009-01-15 2016-02-29 Glaxo Group Limited Compuestos de naftiridin-2(1H)-ona útiles como agentes antibacterianos
TW201326180A (zh) 2011-11-30 2013-07-01 Actelion Pharmaceuticals Ltd ３，７－二取代八氫－２Ｈ－吡啶并［４，３－ｅ］［１，３］□嗪－２－酮抗生素
EA031589B1 (ru) 2014-08-22 2019-01-31 Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед Трициклические азотсодержащие соединения для лечения инфекции, вызываемой neisseria gonorrhoeae
UY36851A (es) 2015-08-16 2017-03-31 Glaxosmithkline Ip Dev Ltd Compuestos para uso en aplicaciones antibacterianas

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB240051A (en) * 1925-01-13 1925-09-24 Chem Fab Auf Actien The manufacture of quinoline-4-aldehyde and its 2-position aryl derivatives
US3714168A (en) * 1970-03-27 1973-01-30 Us Army Preparing alpha-bromomethyl ketones via substituted diethyl malonates
FR2394292A1 (fr) * 1976-03-02 1979-01-12 Krausz Leslie Chimiotherapeutique nouvelle pour la therapeutique anti-neoplasique, dite " dual therapy "
FR2471981A1 (fr) * 1979-12-21 1981-06-26 Pharmindustrie Nouveaux derives de la (piperidyl-4)-2 (quinolyl-4)-1 ethanone, produits intermediaires et procedes pour leur preparation, et leur utilisation comme medicaments
FR2485014A1 (fr) * 1980-06-20 1981-12-24 Pharmindustrie Nouveaux derives de (quinolyl-2, -3 ou -4)-1 (piperidyl ou pyrrolidinyl-2 ou -3)-2 ou -3 ethanone ou propanone, procedes pour leur preparation, et leur utilisation comme medicaments
US4918080A (en) * 1987-04-14 1990-04-17 Glaxo Group Limited Imidazollyl containing ketone derivatives
JPH0424782A (ja) * 1990-05-15 1992-01-28 Canon Inc 文書処理装置
US5866579A (en) * 1997-04-11 1999-02-02 Synaptic Pharmaceutical Corporation Imidazole and imidazoline derivatives and uses thereof
CA2318842A1 (fr) * 1998-01-26 1999-07-29 Julie Dorothy Warrack Derives de quinoline utilises comme antibacteriens
GB9822450D0 (en) * 1998-10-14 1998-12-09 Smithkline Beecham Plc Medicaments
GB9917406D0 (en) * 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
WO2002008224A1 (fr) * 2000-07-26 2002-01-31 Smithkline Beecham P.L.C. Aminopiperidine quinolines et leurs analogues azaisosteres presentant une activite antibacterienne
WO2003064421A1 (fr) * 2002-01-29 2003-08-07 Glaxo Group Limited Derives aminopiperidine

Also Published As

Publication number Publication date
FR2858619A1 (fr) 2005-02-11
CA2535020A1 (fr) 2005-02-24
WO2005016916A3 (fr) 2005-09-29
JP2007501777A (ja) 2007-02-01
WO2005016916A2 (fr) 2005-02-24
EP1654252A2 (fr) 2006-05-10

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Legal Events

Date Code Title Description
CA Change of address
TP Transmission of property
ST Notification of lapse

Effective date: 20100430