FR2840289A1 - PACKAGING BOX FOR BIOLOGICAL PRODUCTS AND THE LIKE - Google Patents
PACKAGING BOX FOR BIOLOGICAL PRODUCTS AND THE LIKE Download PDFInfo
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- FR2840289A1 FR2840289A1 FR0206568A FR0206568A FR2840289A1 FR 2840289 A1 FR2840289 A1 FR 2840289A1 FR 0206568 A FR0206568 A FR 0206568A FR 0206568 A FR0206568 A FR 0206568A FR 2840289 A1 FR2840289 A1 FR 2840289A1
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- cavity
- packaging
- box
- packaging box
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/38—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents with thermal insulation
- B65D81/3825—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents with thermal insulation rigid container being in the form of a box, tray or like container with one or more containers located inside the external container
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K5/00—Heat-transfer, heat-exchange or heat-storage materials, e.g. refrigerants; Materials for the production of heat or cold by chemical reactions other than by combustion
- C09K5/02—Materials undergoing a change of physical state when used
- C09K5/06—Materials undergoing a change of physical state when used the change of state being from liquid to solid or vice versa
- C09K5/066—Cooling mixtures; De-icing compositions
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D3/00—Devices using other cold materials; Devices using cold-storage bodies
- F25D3/02—Devices using other cold materials; Devices using cold-storage bodies using ice, e.g. ice-boxes
- F25D3/06—Movable containers
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D2303/00—Details of devices using other cold materials; Details of devices using cold-storage bodies
- F25D2303/08—Devices using cold storage material, i.e. ice or other freezable liquid
- F25D2303/083—Devices using cold storage material, i.e. ice or other freezable liquid using cold storage material disposed in closed wall forming part of a container for products to be cooled
- F25D2303/0831—Devices using cold storage material, i.e. ice or other freezable liquid using cold storage material disposed in closed wall forming part of a container for products to be cooled the liquid is disposed in the space between the walls of the container
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D2303/00—Details of devices using other cold materials; Details of devices using cold-storage bodies
- F25D2303/08—Devices using cold storage material, i.e. ice or other freezable liquid
- F25D2303/085—Compositions of cold storage materials
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D2331/00—Details or arrangements of other cooling or freezing apparatus not provided for in other groups of this subclass
- F25D2331/80—Type of cooled receptacles
- F25D2331/804—Boxes
Landscapes
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Combustion & Propulsion (AREA)
- Thermal Sciences (AREA)
- Mechanical Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Materials Engineering (AREA)
- Organic Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Packages (AREA)
Abstract
La caisse de conditionnement de produits biologiques et en particulier sanguins permet leur transport et leur conservation pendant une durée prédéterminée à une température de conservation sensiblement constante inférieure à la température ambiante.La caisse comprend une caisse extérieure (1) de forme appropriée pour le transport et contenant une boîte (2) renfermant le produit biologique, une matière isolante (3) remplissant au moins en partie l'espace compris entre ladite boîte (2) et les parois extérieures de la caisse (1). La boîte (2) est contenue dans une enceinte creuse (4) sensiblement sphérique renfermant une matière préalablement solidifiée dont la température de fusion est sensiblement égale à ladite température de conservation souhaitée pour lesdits produits biologiques.The packaging box for biological products and in particular blood allows their transport and storage for a predetermined period of time at a substantially constant storage temperature below ambient temperature. The box includes an outer box (1) of suitable shape for transport and containing a box (2) containing the biological product, an insulating material (3) at least partially filling the space between said box (2) and the outer walls of the box (1). The box (2) is contained in a hollow chamber (4) which is substantially spherical containing a material previously solidified, the melting point of which is substantially equal to said desired storage temperature for said biological products.
Description
par rapport a ladite direction de deplacement (710).relative to said direction of movement (710).
Caisse de conditionnement de produits biologiques et analogues La presente invention concerne une caisse de conditionnement de produits biologiques et en particulier sanguine pour leur transport et leur conservation pendant une duree predeterminee a une temperature de conservation Box for packaging biological products and the like The present invention relates to a box for packaging biological products and in particular blood products for their transport and storage for a predetermined period at a storage temperature.
s sensiblement constante.s substantially constant.
Dans une application preferee de l' invention, il stagit de transporter et de conserver a temperature constante In a preferred application of the invention, he learns to transport and store at constant temperature
pendant au moins 72 heures, par exemple, suivant le cas a - for at least 72 hours, for example, depending on the case a -
18 C ou a + 4 C des echantillons biologiques tels que des 18 C or a + 4 C biological samples such as
tubes d'hemodialyse.hemodialysis tubes.
Dans le cadre de cette application, on peut envisager le transport de ces produits dans des camions refrigeres ou dans As part of this application, we can consider the transport of these products in refrigerated trucks or in
des caisses refrigerees ou remplies de neige carbonique. crates refrigerated or filled with dry ice.
Cependant, de telles solutions vent exclues par la presente invention car trop couteuses ou trop compliquees a However, such solutions are excluded by the present invention because they are too expensive or too complicated to
mettre en muvre.put into action.
La presente invention a pour but de fournir une caisse de conditionnement pour conserver les produits a transporter, pouvant etre transportee dans des vehicules de fret classique, ctest-a-dire depourvus de moyens particuliers de maintien a une temperature constante, et ayant un rapport poids/volume optimise, ce qui permet de reduire le cout de transport. L'etat de la technique montre que l'on connalt des caisses de conditionnement pour des produits tels que du sang ou des produits pharmaceutiques ou autres (creme glacee, etc) comprenant en t ant que moyen de maintien a basse temperature: - des blocs de grace; - la chaleur latente de fusion d'alliages moleculaires ou liquides eutectiques; - un echangeur thermique; - un compresseur frigorifique; - lteffet Peltier. Ces caisses de conditionnement ne conviennent pas pour ['application specifiquement consideree par la presente invention pour les raisons qu'elles vent soient: - trop couteuses ou compliquees a mettre en euvre, elles ne permettent pas un maintien a une temperature suffisamment basse, ou suffisamment constante ou pendant une duree suffisamment longue, The object of the present invention is to provide a packaging case for storing the products to be transported, which can be transported in conventional freight vehicles, that is to say without specific means of maintaining a constant temperature, and having a weight ratio. / optimized volume, which reduces transport costs. The state of the art shows that packaging cases are known for products such as blood or pharmaceutical or other products (ice cream, etc.) comprising as a means of maintaining at low temperature: - blocks of grace; - the latent heat of fusion of molecular alloys or eutectic liquids; - a heat exchanger; - a refrigeration compressor; - the Peltier effect. These packaging cases are not suitable for the application specifically considered by the present invention for the reasons that they are: - too expensive or complicated to use, they do not allow maintenance at a sufficiently low temperature, or sufficiently constant or for a sufficiently long period,
- trop pesantes.- too heavy.
L'etat de la technique ci-dessus est illustre en particulier par le brevet francais n 98 09526 et le brevet The above state of the art is illustrated in particular by French patent no 98 09526 and the patent
europeen n 0900072.European n 0900072.
Le but de la presente invention est de remedier aux inconvenients des caisses de conditionnement connues, en creant une caisse de conditionnement pour des produits biologiques, pouvant etre transportee dans des vehicules classiques, ne necessitant aucun apport exterieur d'energie pour maintenir les produits a la temperature constante determinee, la duree du maintien de cette temperature etant suffisante et en tout cas compatible avec la duree du The purpose of the present invention is to remedy the drawbacks of known packaging boxes, by creating a packaging box for organic products, which can be transported in conventional vehicles, requiring no external energy input to keep the products at the constant temperature determined, the duration of maintaining this temperature being sufficient and in any case compatible with the duration of the
2s transport dans lesdits vehicules classiques. 2s transport in said conventional vehicles.
L' invention vise ainsi une caisse de conditionnement de produits biologiques et en particulier sanguine pour leur transport et leur conservation pendant une duree predeterminee a une temperature de conservation sensiblement constante inferieure a la temperature ambiante, comprenant une caisse exterieure de forme appropriee pour le transport et contenant une bo1te renfermant le produit biologique, une matiere isolante remplissant au moins en partie l'espace compris entre ladite bolte et les parois exterieures de la caisse. Suivant ['invention, cette caisse de conditionnement est caracterisee en ce que la bo1te est contenue dans une enceinte creuse sensiblement spherique renfermant une matiere prealablement solidifiee dont la temperature de fusion est sensiblement egale a ladite temperature de conservation The invention thus relates to a box for packaging biological and in particular blood products for their transport and their storage for a predetermined period of time at a substantially constant storage temperature below ambient temperature, comprising an external box of suitable shape for transporting and containing a box containing the biological product, an insulating material filling at least partially the space between said bowl and the outer walls of the box. According to the invention, this packaging case is characterized in that the box is contained in a hollow substantially spherical enclosure containing a previously solidified material whose melting temperature is substantially equal to said preservation temperature.
souhaitee pour lesdits produits biologiques. desired for said organic products.
La matiere en fusion contenue a l'interieur de l'enceinte sensiblement spherique reste a une temperature constante pendant une duree qui est fonction de sa nature, de sa masse, de sa chaleur latente de fusion et des deperditions The molten material contained inside the substantially spherical enclosure remains at a constant temperature for a duration which is a function of its nature, its mass, its latent heat of fusion and the losses.
thermiques vers l'exterieur.thermal towards the outside.
Ces deperditions thermiques vers l'exterieur vent minimisees du fait de la forme spherique de l'enceinte creuse dans laquelle est contenue la bolte qui renferme les produits These thermal losses towards the outside wind are minimized due to the spherical shape of the hollow enclosure in which the bolte which contains the products is contained.
a conserver.to conserve.
Les deperditions vent egalement minimisees du fait que l'enceinte spherique est entouree par la matiere isolante qui The losses are also minimized because the spherical enclosure is surrounded by the insulating material which
remplit la caisse de conditionnement. fills the packing box.
Ainsi, en regle generale le produit biologique peut etre conserve a l'interieur de la caisse a une temperature de Thus, as a rule, the organic product can be stored inside the box at a temperature of
l'ordre par exemple de - 18 C, alors que la caisse est elle- the order for example of - 18 C, while the case is itself
meme a une temperature ambiante de 27 C, pendant au moins 72 heures. Cette duree est largement suffisante pour transporter la caisse renfermant le produit biologique, par exemple, d'un laboratoire vers un autre laboratoire ou vers un hBpital ou inversement. Selon une version preferee de ['invention ltenceinte creuse sensiblement spherique comporte une cavite interne pour loger ladite bo1te et des moyens pour introduire cette even at an ambient temperature of 27 C, for at least 72 hours. This duration is more than sufficient to transport the box containing the biological product, for example, from a laboratory to another laboratory or to a hospital or vice versa. According to a preferred version of the invention, the substantially spherical hollow enclosure comprises an internal cavity for housing said box and means for introducing this
derriere dans la cite cavite.behind in the cavity city.
De preference, ladite cavite a une forme sensiblement Preferably, said cavity has a shape substantially
complementaire de celle de ladite bolte. complementary to that of said bolt.
Grace a cette disposition, la bolte renfermant les produits a conserver se trouve en relation d'echange thermique direct avec la paroi de la cavite qui est elle-meme en relation d'echange thermique direct avec la matiere en Thanks to this arrangement, the bolte containing the products to be preserved is in direct heat exchange relation with the wall of the cavity which is itself in direct heat exchange relation with the material in question.
fusion situee a l'interieur de l'enceinte spherique. fusion located inside the spherical enclosure.
Cette disposition est ainsi avantageuse sur le plan This arrangement is thus advantageous in terms of
thermique et favorable a la conservation des produits. thermal and favorable for product conservation.
Dans une realisation avantageuse de ['invention, l'enceinte creuse est en deux parties amovibles pour In an advantageous embodiment of the invention, the hollow enclosure is in two removable parts for
permettre l'acces a ladite cavite.allow access to said cavity.
Cette disposition facilite la mise en place de la bolte This arrangement facilitates the installation of the bolte
renfermant les produits a l'interieur de ltenceinte creuse. containing the products inside the hollow enclosure.
De preference, chacune des deux parties de lienceinte Preferably, each of the two parts of the audience
creuse est moulee d'une seule piece en matiere synthetique. hollow is molded in one piece from synthetic material.
Cette caracteristique permet d'obtenir une enceinte creuse economique a realiser, par exemple par rotomoulage, permettant de reduire d'une maniere efficace, les This characteristic makes it possible to obtain an economical hollow enclosure to be produced, for example by rotational molding, making it possible to reduce in an efficient manner, the
deperditions de chaleur.heat loss.
Selon une autre particularite de ['invention, ladite enceinte creuse est separee de ladite matiere isolante par According to another feature of the invention, said hollow enclosure is separated from said insulating material by
une lame d'air.an air gap.
Cette lame d' air entourant l'enceinte creuse, permet de 2s reduire encore davantage des deperditions thermiques vers l'exterieur. La matiere prealablement solidifiee contenue dans l'enceinte spherique peut etre une matiere eutectique a base de sel ou d'eau ou une matiere a changement de phases par This air space surrounding the hollow enclosure allows 2s to further reduce heat loss to the outside. The previously solidified material contained in the spherical enclosure can be a eutectic material based on salt or water or a material with phase change by
alliages moleculaires.molecular alloys.
D'autres particularites et avantages de l' invention Other features and advantages of the invention
apparaltront encore dans la description ci-apres. will appear again in the description below.
s Aux dessins annexes donnes a titre d'exemples non limitatifs: s In the annexed drawings given by way of nonlimiting examples:
- la figure 1 est une vue en perspective et en demi- - Figure 1 is a perspective view in half
coupe d' un premier mode de realisation d' une enceinte s spherique pour une caisse de conditionnement selon ['invention, - la figure 2 est une vue analogue a la figure 1 concernant un second mode de realisation d'une enceinte spherique, - la figure 3 est une vue en perspective et en position ouverte d'une caisse de conditionnement renfermant une enceinte spherique selon le premier mode de realisation, section of a first embodiment of a spherical enclosure for a packaging case according to the invention, - Figure 2 is a view similar to Figure 1 relating to a second embodiment of a spherical enclosure, - the FIG. 3 is a perspective view and in the open position of a packaging box containing a spherical enclosure according to the first embodiment,
- la figure 4 est une vue en perspective et en demi- - Figure 4 is a perspective view in half
coupe d'une caisse de conditionnement ouverte, renfermant une enceinte spherique qui est elle-meme ouverte, - la figure 5 est une vue analogue a la figure 3, la caisse de conditionnement renfermant une enceinte spherique selon le second mode de realisation, - la figure 6 est une vue analogue a la figure 4, la caisse de conditionnement renfermant une enceinte spherique section of an open packaging box, containing a spherical enclosure which is itself open, - Figure 5 is a view similar to Figure 3, the packaging box containing a spherical enclosure according to the second embodiment, - the Figure 6 is a view similar to Figure 4, the packaging box containing a spherical enclosure
selon le second mode ci-dessus.according to the second mode above.
Les figures annexees representent une caisse de conditionnement de produits biologiques et en particulier sanguine pour leur transport et leur conservation pendant une 2s duree predeterminee a une temperature de conservation The appended figures represent a box for packaging biological products and in particular blood products for their transport and storage for a predetermined period of time at a storage temperature.
sensiblement constante inferieure a la temperature ambiante. substantially constant below room temperature.
Cette caisse comprend une caisse exterieure (1) de forme appropriee, par exemple cubique, pour le transport qui contient une bolte (2) renfermant le produit biologique. Une matiere isolante (3) remplit au moins en partie l'espace compris entre la bolte (2) et les parois exterieures de la This box comprises an external box (1) of suitable shape, for example cubic, for transport which contains a container (2) containing the biological product. An insulating material (3) at least partially fills the space between the bowl (2) and the outer walls of the
caisse (1).body (1).
Conformement a l' invention, la bolte (2) est contenue dans une enceinte creuse (4, 5) sensiblement spherique renfermant une matiere prealablement solidifiee dont la temperature de fusion est sensiblement egale a ladite s temperature de conservation souhaitee pour lesdits produits biologiques. Comme montre notamment par les figures 1 et 2, l'enceinte creuse (4, 5) sensiblement spherique comporte une cavite interne (6) pour loger la bolte (2) et des moyens pour According to the invention, the bowl (2) is contained in a hollow enclosure (4, 5) substantially spherical containing a previously solidified material whose melting temperature is substantially equal to said desired storage temperature for said biological products. As shown in particular in FIGS. 1 and 2, the substantially spherical hollow enclosure (4, 5) comprises an internal cavity (6) for housing the bolte (2) and means for
introduire cette derriere dans ladite cavite (6). introduce this behind in said cavity (6).
La cavite (6) a une forme sensiblement complementaire de celle de ladite bolte (2). Dans l'exemple represente, la The cavity (6) has a shape substantially complementary to that of said bolt (2). In the example shown, the
bolte (2) et la cavite (6) vent cylindriques. bolte (2) and the cavity (6) cylindrical wind.
L'enceinte creuse (4, 5) est en deux parties amovibles The hollow enclosure (4, 5) is in two removable parts
pour permettre l'acces a ladite cavite (6). to allow access to said cavity (6).
Dans le mode de realisation des figures 1, 3 et 4, l'enceinte creuse (4) est constituee par deux parties hemispheriques (4a, 4b), chacune d'elles comportant une paroi equatoriale plane (4c, 4d) presentant une demicavite centrale (6a, 6b) faisant saillie vers l'interieur et ouverte vers l'exterieur, de telle sorte que lorsque les deux parties hemispheriques (4a, 4b) vent jointes les deux demi-cavites constituent la cavite (6a, 6b) recevant la bo1te (2). Par ailleurs, dans ce mode de realisation les deux parties hemispheriques (4a, 4b) vent reliees l'une a l'autre par une In the embodiment of Figures 1, 3 and 4, the hollow enclosure (4) is constituted by two hemispherical parts (4a, 4b), each of them comprising a plane equatorial wall (4c, 4d) having a central half-cavity (6a, 6b) projecting inwards and open towards the outside, so that when the two hemispherical parts (4a, 4b) are joined the two half-cavities constitute the cavity (6a, 6b) receiving the box (2). Furthermore, in this embodiment, the two hemispherical parts (4a, 4b) are connected to each other by a
articulation (7).articulation (7).
Dans le mode de realisation des figures 2, 5 et 6, la cavite (6) s'etend vers l'interieur de l'enceinte creuse (5) a partir de la surface exterieure spherique. L'autre partie de ltenceinte creuse est constituee par un bouchon (8) obturant l'ouverture d'acces a cette cavite (6). Par ailleurs, la cavite (6) est raccordee a la surface exterieure spherique par une paroi tronconique (9) evasee vers In the embodiment of Figures 2, 5 and 6, the cavity (6) extends towards the inside of the hollow enclosure (5) from the outer spherical surface. The other part of the hollow enclosure is constituted by a plug (8) closing the access opening to this cavity (6). Furthermore, the cavity (6) is connected to the external spherical surface by a frustoconical wall (9) flared towards
l'exterieur sur laquelle s'appuie ledit bouchon (8). the exterior on which said plug (8) rests.
Dans les deux modes de real i sat ion, chacune des deux parties de l'enceinte creuse (4, 5) est moulee d'une seule piece en matiere synthetique, telle qu'une polyolefine. Une In both embodiments, each of the two parts of the hollow enclosure (4, 5) is molded in one piece from synthetic material, such as a polyolefin. A
telle forme peut etre realisee facilement par rotomoulage. such a shape can be easily produced by rotational molding.
On volt egalement sur les figures 3 et 5, que l'enceinte creuse (4, 5) est separee de ladite matiere isolante (3) par It is also shown in FIGS. 3 and 5 that the hollow enclosure (4, 5) is separated from said insulating material (3) by
une lame d' air (10).an air knife (10).
La matiere prealablement solidifiee remplissant l'enceinte spherique (4, 5) peut etre une matiere eutectique a base d'eau et de sel ou une matiere a changement de phases The previously solidified material filling the spherical enclosure (4, 5) may be a eutectic material based on water and salt or a phase change material
par alliages moleculaires.by molecular alloys.
Le tableau ci-apres montre la composition et les The table below shows the composition and
caracteristiques de quelques liquides eutectiques. characteristics of some eutectic liquids.
Eutectique en masse de Point Enthalpie de sel d'eutexie transformation sec dissous ( C) (kJ/kg) Eau 0 335 Sulfate de sodium 3.8 -1.2 334 Carbone de sodium 5.9 -2.1 324 Sulfate de 19 -3.9 244 magnesium Sulfate de zinc 27.2 -6.55 213 Chlorure de 19.7 -11.1 301 potassium Chromate de 35. 5 -11.4 206 potassium Chlorure 18.7 -15.8 309 d'ammonium Nitrate d'ammonium 41.2 -17.4 284 Nitrate de sodium 44.8 -18.5 241 Chl i d-sodlm; i;2<i-712-- 246; Mass Eutectic of Enthalpy of eutexia salt dissolved dry transformation (C) (kJ / kg) Water 0 335 Sodium sulfate 3.8 -1.2 334 Sodium carbon 5.9 -2.1 324 19 -3.9 sulfate 244 magnesium Zinc sulfate 27.2 -6.55 213 Chloride of 19.7 -11.1 301 potassium Chromate of 35.5 -11.4 206 potassium Chloride 18.7 -15.8 309 ammonium Ammonium nitrate 41.2 -17.4 284 Sodium nitrate 44.8 -18.5 241 Chl i d-sodlm; i; 2 <i-712-- 246;
orure, --.;.orure, -.;.
Chlorure de 29.8 -55 155 calcium Ainsi, le nitrate de sodium et le chlorure de sodium en solution de l'eau permettent apres solidification d'obtenir un palier de fusion a une temperature constante comprise Chloride de 29.8 -55 155 calcium Thus, sodium nitrate and sodium chloride in solution of water allow after solidification to obtain a level of fusion at a constant temperature included
entre -18 et -21 C environ.between -18 and -21 C approximately.
Leur enthalpie de transformation ou chaleur latente de fusion est suffisamment elevee pour maintenir la temperature constante pendant une duree qui peut dans certaines Their enthalpy of transformation or latent heat of fusion is high enough to keep the temperature constant for a period which can in some cases
conditions depasser 72 heures.conditions exceed 72 hours.
Les ALCAL Ce vent des materiaux a changement de phases par alliages moleculaires, appeles MCPAM. Ils permettent un ajustement de la temperature de fonctionnement Tf par le biais de la composition et, par rapport aux eutectiques, permet tent une maltri se sur une gamme de temperature de solidification tres large, allant de -50 C a +100 C. Leurs caracteristiques vent les suivantes: ALCAL This wind of materials with phase change by molecular alloys, called MCPAM. They allow an adjustment of the operating temperature Tf through the composition and, compared to the eutectics, allow a maltri se over a very wide solidification temperature range, going from -50 C to +100 C. Their characteristics the following:
39T appl i ca ti on = Tf.39T appl i ca ti on = Tf.
Fenetre thermique ATf etroite (0.5 a 2 C). Narrow ATf thermal window (0.5 to 2 C).
Energie stockee plus faiblement que les eutectiques Energy stored weaker than eutectics
(149 KJ / Kg en moyenne).(149 KJ / Kg on average).
Reutilisables a volonte.Reusable at will.
Les ALCAL ont ete concus par le Centre Physique Moleculaire et Optique Hertzienne (CPMOH) de l'Universite The ALCALs were designed by the Center Physique Moleculaire et Optique Hertzienne (CPMOH) of the University
Bordeaux I et vent brevetes (voir brevets...). Bordeaux I and wind patents (see patents ...).
On donne ci-apres, a titre d'exemple non limitatif, les caracteristiques d'une caisse de conditionnement selon ['invention. Dimensions de la caisse exterieure 1: 350 x 350 x The characteristics of a packaging case according to the invention are given below, by way of nonlimiting example. Dimensions of the external box 1: 350 x 350 x
350 mm.350 mm.
Matiere isolante 3: mousse de polyurethanne, Insulating material 3: polyurethane foam,
Conductivite: 0,027 W (m.k), epaisseur moyenne: 60 mm. Conductivity: 0.027 W (m.k), average thickness: 60 mm.
Lame d' air 9: epaisseur 15 mm.Air blade 9: thickness 15 mm.
Rayon de l'enceinte spherique: 100 mm. Radius of the spherical enclosure: 100 mm.
S Matiere a changement de phase type eutectique: chaleur latente de fusion: 275 KJ / Kg, temperature de fusion: S Eutectic type phase change material: latent heat of fusion: 275 KJ / Kg, temperature of fusion:
-20 C.-20 C.
Bolte interieure 2: cylindrique 50 ml. Inner bowl 2: cylindrical 50 ml.
Une tel le cai sse de condit ionnement a permis de maintenir, 5 tubes d'hemodialyse disposes a l'interieur de l'enceinte spherique a une temperature inferieure a -18 C pendant 72 heures, alors que la caisse elle-m8me etait dans Such a packaging box made it possible to maintain 5 hemodialysis tubes placed inside the spherical enclosure at a temperature below -18 C for 72 hours, while the box itself was in
une atmosphere a 27 C.an atmosphere at 27 C.
Des essais compares, ont permis d'etablir que l'utilisation d'une enceinte spherique, au lieu d'une enceinte cubique permet de prolonger la duree de Comparative tests have established that the use of a spherical enclosure, instead of a cubic enclosure, makes it possible to extend the duration of
conditionnement de 23%.23% conditioning.
De m8me, la lame d' air comprise entre l'enceinte spherique et l'isolant permet de prolonger de 10% la duree du Likewise, the air space between the spherical enclosure and the insulation makes it possible to extend the duration of the
conditionnement.conditioning.
L' invention permet de conserver les produits pendant 72 heures sans aj out de neige carbonique et sans systemes complexes de conditionnement. Wile concerne les produits de The invention makes it possible to store the products for 72 hours without adding dry ice and without complex packaging systems. Wile concerns the products of
faible volume (faible masse thermique). low volume (low thermal mass).
La caisse de conditionnement peut 8tre transportee par The packing box can be transported by
des vehicules non dedies.non-dedicated vehicles.
Les produits de refroidissement peuvent se solidifier dans de congelateurs (temperatures negatives) et dans des Coolants can solidify in freezers (negative temperatures) and in
etuves (temperatures positives).ovens (positive temperatures).
L'invention repond aux normes specifiques imposees par l'ONU. Ces normes definissent les conditions d'emballage, d'etiquetage, de documentations d'expedition et d'acheminement. En termes de conception, senles les conditions d'emballage vent utiles. Ces normes imposent d'utiliser un systeme a triple emballage agree comprenant: - Un recipient primaire etanche contenant la culture ou lteventuel produit biologique (la quantite de matiere The invention meets the specific standards imposed by the UN. These standards define the conditions of packaging, labeling, shipping and routing documentation. In terms of design, only the packaging conditions are useful. These standards require the use of an approved triple packaging system comprising: - A sealed primary container containing the culture or any biological product (the amount of material
infectieuse est limitee a 50 ml ou 50 g par colis). infectious is limited to 50 ml or 50 g per package).
- Ce recipient est insere dans une bolte secondaire etanche, resistant aux chocs, tapissee d'un materiau - This container is inserted in a waterproof, impact resistant secondary container lined with a material
absorbent en quantite suffisante.absorb in sufficient quantity.
- L'ensemble est place dans un emballage tertiaire resistant dont la plus petite dimension est superieure a 10 cm, afin de porter le marquage specifique et l'etiquetage reglementaire. - L'accumulateur de froid est place a l'exterieur de l'emballage secondaire et dans un emballage tertiaire isolant - The set is placed in a resistant tertiary packaging whose smallest dimension is greater than 10 cm, in order to carry the specific marking and regulatory labeling. - The cold accumulator is placed outside the secondary packaging and in an insulating tertiary packaging
agree etanche.agree waterproof.
- L'emballage secondaire doit demeurer cafe meme apres - The secondary packaging must remain coffee even after
liquefaction de l'accumulateur de froid. liquefaction of the cold accumulator.
- Si plusieurs emballages primaires vent places dans un m8me emballage secondaire, il faut les emballer separement - If several primary packages are placed in the same secondary packaging, they must be packaged separately
pour eviter tout contact.to avoid contact.
- Marquer de facon durable le nom de l'expediteur et son - Mark in a lasting way the name of the sender and his
numero de telephone sur la paroi exterieure du colis. telephone number on the outside wall of the parcel.
La caisse de conditionnement selon l' invention peut etre 2s utilisee notamment pour: - Les transferts entre les laboratoires; - Les transferts d'echantillons entre les hopitaux et les centres de collecte; - Les transferts de poches de sang entre les hopitaux et les centres de collecte; - Les transferts de poches de plasma entre les hopitaux et un centre parisien; - La collecte d'organes pour les greffes; - Le transport de tout element de falble volume a The packaging case according to the invention can be used in particular for: - Transfers between laboratories; - Transfers of samples between hospitals and collection centers; - Transfers of blood bags between hospitals and collection centers; - Transfers of plasma bags between hospitals and a Paris center; - Organ harvesting for transplants; - The transport of any element of falble volume to
conditionner en temperature.condition in temperature.
Claims (10)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0206568A FR2840289A1 (en) | 2002-05-29 | 2002-05-29 | PACKAGING BOX FOR BIOLOGICAL PRODUCTS AND THE LIKE |
| AU2003273561A AU2003273561A1 (en) | 2002-05-29 | 2003-03-28 | Packing container for biological products and analogous items |
| PCT/FR2003/000991 WO2003101861A2 (en) | 2002-05-29 | 2003-03-28 | Packing container for biological products and analogous items |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0206568A FR2840289A1 (en) | 2002-05-29 | 2002-05-29 | PACKAGING BOX FOR BIOLOGICAL PRODUCTS AND THE LIKE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2840289A1 true FR2840289A1 (en) | 2003-12-05 |
Family
ID=29558812
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR0206568A Pending FR2840289A1 (en) | 2002-05-29 | 2002-05-29 | PACKAGING BOX FOR BIOLOGICAL PRODUCTS AND THE LIKE |
Country Status (3)
| Country | Link |
|---|---|
| AU (1) | AU2003273561A1 (en) |
| FR (1) | FR2840289A1 (en) |
| WO (1) | WO2003101861A2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005066559A2 (en) * | 2004-01-08 | 2005-07-21 | Bernhard Sixt | Transport container for keeping frozen material chilled |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010500967A (en) | 2006-07-20 | 2010-01-14 | ザ ジェネラル ホスピタル コーポレイション | Methods, compositions, and kits for selective activation of protoxins through combinatorial targeting |
| GB2447665A (en) * | 2007-03-19 | 2008-09-24 | Angus Burnett Ewart | Complete cryo encapsualtion device for biological specimen vials |
| EP3280962B1 (en) * | 2015-04-06 | 2019-05-22 | The Sure Chill Company Limited | Mobile refrigeration apparatus |
| AT522703B1 (en) * | 2019-06-24 | 2023-07-15 | Rep Ip Ag | packaging for pharmaceutical products |
| AT522704B1 (en) * | 2019-06-24 | 2023-07-15 | Rep Ip Ag | packaging for pharmaceutical products |
| AT526147B1 (en) | 2022-08-19 | 2023-12-15 | Rep Ip Ag | Packaging for pharmaceutical products |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1004791A (en) * | 1963-06-19 | 1965-09-15 | Salterpak Ltd | Improvements relating to thermally-insulated cases |
| US5405012A (en) * | 1993-10-13 | 1995-04-11 | Purisys Inc. | Insulated container for transporting temperature sensitive analytical samples |
| DE29912569U1 (en) * | 1999-07-19 | 2000-12-28 | Woehr Martin | Cooling tank |
-
2002
- 2002-05-29 FR FR0206568A patent/FR2840289A1/en active Pending
-
2003
- 2003-03-28 AU AU2003273561A patent/AU2003273561A1/en not_active Abandoned
- 2003-03-28 WO PCT/FR2003/000991 patent/WO2003101861A2/en not_active Application Discontinuation
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1004791A (en) * | 1963-06-19 | 1965-09-15 | Salterpak Ltd | Improvements relating to thermally-insulated cases |
| US5405012A (en) * | 1993-10-13 | 1995-04-11 | Purisys Inc. | Insulated container for transporting temperature sensitive analytical samples |
| DE29912569U1 (en) * | 1999-07-19 | 2000-12-28 | Woehr Martin | Cooling tank |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005066559A2 (en) * | 2004-01-08 | 2005-07-21 | Bernhard Sixt | Transport container for keeping frozen material chilled |
| WO2005066559A3 (en) * | 2004-01-08 | 2005-11-10 | Bernhard Sixt | Transport container for keeping frozen material chilled |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003273561A8 (en) | 2003-12-19 |
| WO2003101861A2 (en) | 2003-12-11 |
| WO2003101861A3 (en) | 2007-10-25 |
| AU2003273561A1 (en) | 2003-12-19 |
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