EP1477751B1 - Isothermal package for heat sensitive products and method for its production - Google Patents
Isothermal package for heat sensitive products and method for its production Download PDFInfo
- Publication number
- EP1477751B1 EP1477751B1 EP04291214A EP04291214A EP1477751B1 EP 1477751 B1 EP1477751 B1 EP 1477751B1 EP 04291214 A EP04291214 A EP 04291214A EP 04291214 A EP04291214 A EP 04291214A EP 1477751 B1 EP1477751 B1 EP 1477751B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- cold
- container
- inner shell
- order
- outer shell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title claims abstract description 25
- 230000004888 barrier function Effects 0.000 claims abstract description 62
- 238000000926 separation method Methods 0.000 claims abstract description 8
- 238000001816 cooling Methods 0.000 claims description 46
- 238000004806 packaging method and process Methods 0.000 claims description 28
- 238000003780 insertion Methods 0.000 claims description 8
- 230000037431 insertion Effects 0.000 claims description 8
- 239000000126 substance Substances 0.000 claims description 7
- 230000005540 biological transmission Effects 0.000 claims description 4
- 239000006260 foam Substances 0.000 claims description 3
- 239000011810 insulating material Substances 0.000 claims 1
- 238000009451 isothermal packaging Methods 0.000 abstract description 8
- 239000002826 coolant Substances 0.000 abstract description 2
- 230000001105 regulatory effect Effects 0.000 description 32
- 238000007710 freezing Methods 0.000 description 7
- 230000008014 freezing Effects 0.000 description 7
- 239000000463 material Substances 0.000 description 5
- 239000004033 plastic Substances 0.000 description 5
- 229920003023 plastic Polymers 0.000 description 5
- 238000010257 thawing Methods 0.000 description 5
- 238000009413 insulation Methods 0.000 description 4
- 238000005259 measurement Methods 0.000 description 3
- 238000012858 packaging process Methods 0.000 description 3
- 239000004743 Polypropylene Substances 0.000 description 2
- 230000000295 complement effect Effects 0.000 description 2
- -1 polypropylene Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 239000003507 refrigerant Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 239000004484 Briquette Substances 0.000 description 1
- 150000001336 alkenes Chemical class 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 230000005496 eutectics Effects 0.000 description 1
- 239000000383 hazardous chemical Substances 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 239000012774 insulation material Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 210000002445 nipple Anatomy 0.000 description 1
- JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 description 1
- 239000005022 packaging material Substances 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 238000005057 refrigeration Methods 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 230000011664 signaling Effects 0.000 description 1
- 239000002937 thermal insulation foam Substances 0.000 description 1
- 239000011345 viscous material Substances 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Images
Classifications
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D3/00—Devices using other cold materials; Devices using cold-storage bodies
- F25D3/02—Devices using other cold materials; Devices using cold-storage bodies using ice, e.g. ice-boxes
- F25D3/06—Movable containers
- F25D3/08—Movable containers portable, i.e. adapted to be carried personally
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D2303/00—Details of devices using other cold materials; Details of devices using cold-storage bodies
- F25D2303/08—Devices using cold storage material, i.e. ice or other freezable liquid
- F25D2303/082—Devices using cold storage material, i.e. ice or other freezable liquid disposed in a cold storage element not forming part of a container for products to be cooled, e.g. ice pack or gel accumulator
- F25D2303/0822—Details of the element
- F25D2303/08221—Fasteners or fixing means for the element
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D2331/00—Details or arrangements of other cooling or freezing apparatus not provided for in other groups of this subclass
- F25D2331/80—Type of cooled receptacles
- F25D2331/803—Bottles
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D2331/00—Details or arrangements of other cooling or freezing apparatus not provided for in other groups of this subclass
- F25D2331/80—Type of cooled receptacles
- F25D2331/804—Boxes
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D2500/00—Problems to be solved
- F25D2500/02—Geometry problems
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D2600/00—Control issues
- F25D2600/04—Controlling heat transfer
Definitions
- the present invention relates to the field of isothermal packaging.
- the invention relates more particularly to an isothermal packaging device for thermosensitive products, hazardous materials, infectious substances, biologically active products, etc. used in particular in biotechnology, chemistry, pharmacy or any other type of product tolerating only a very small variation in temperature.
- thermosensitive products it is known, in the prior art, a packaging process for thermosensitive products to be stored between 2 and 10 ° C.
- the product is stored between two or more inner walls of thermal insulation forming an internal cavity in contact with accumulators refrigerated cold at a temperature of the order of -20 ° C.
- a bottle of product is thus wrapped in a first insulation container, itself placed in a plastic envelope filled with insulating foam.
- Such a mode of packaging allows the transport of sensitive products while maintaining the desired temperature, even in cold or hot environments.
- this process requires a large volume of insulation to avoid freezing the product to be preserved.
- freezing must be avoided because it irreversibly alters the essential properties of the products, for example causing a deterioration of the active principle of a pharmaceutical composition. Therefore, such a system is not suitable for storing large volumes of thermosensitive product not accepting freezing.
- the thickness of the insulating layer must not be too high, otherwise the packaging will be too bulky and excessively heavy and cause excessive transportation costs.
- the WO 00/12409 discloses a package provided with an outer wrapping layer incorporating coolant material cooled to a temperature below 0 ° C, and an inner layer of removable separation between the product to be preserved and the outer layer.
- the separation layer contains a volume of water depending on the amount of refrigerant material of the outer layer.
- the present invention therefore aims to overcome one or more of the disadvantages of the prior art by defining a reliable method of packaging heat-sensitive products in a transport packaging to maintain a conservation temperature always greater than 0 ° C.
- the cold accumulator contains a volume 2 to 5 times higher than the volume contained in the cold regulating barrier container, the cold accumulator being frozen at a temperature below -15 ° C before the step of pairing and keeping in contact while the cold regulating barrier container is at a temperature of the order of 3 to 25 ° C.
- the inner envelope and the outer envelope are parallelepipedal, the inner envelope being provided with two flaps oriented in a first horizontal direction to form a basket and placed in the center of the outer envelope, the dimension of the inner envelope in the first direction being determined to provide a lateral spacing between the outer shell and each of the two side faces of the inner shell perpendicular to the first direction, the flaps being extended in the first direction to cover the two lateral spacings thus formed.
- the step of pairing and keeping in contact comprises a junction of the male-female type between the cold regulating barrier container and the cold accumulator, the cold regulating barrier container being of flattened shape.
- the step of pairing and keeping in contact is carried out in a holster sufficiently narrow to press the cold regulating barrier container against the cold accumulator, the cold regulating barrier container being of flattened shape. .
- a cooling unit is inserted between the flaps of the inner casing and a closure member of the outer casing.
- An object of the invention is also to define an isothermal packaging device for temperature sensitive products.
- the invention relates to an isothermal packaging device for implementing the method of packaging heat-sensitive products according to the invention, comprising an inner envelope shaped to delimit a heat-sensitive product storage compartment, an outer envelope or a transport case of determined volume sufficient to incorporate the housing and define at least one localized spacing on a part of the periphery of the housing, characterized in that a removable cooling unit is housed in said spacing, the cooling unit comprising a cold accumulator positioned against the outer casing and a cold regulating barrier container filled with a substance having a viscosity number of at least 100 Pa.s, the cold regulating barrier container being contiguous and held in contact by holding means with at least one surface of the cold accumulator for sea a separation between the inner envelope and the cold accumulator.
- the cold accumulator contains a gel capable of being frozen at a temperature below -15 ° C., the filling volume of the cold accumulator being 2 to 5 times higher than the volume of the cold accumulator. filling the cold barrier container, so as to maintain the housing at a temperature above 0 ° C.
- the inner envelope and the outer envelope are parallelepipedal, the inner envelope being provided with two flaps oriented in a first horizontal direction to form a basket and placed in the center of the outer envelope, the dimension of the inner shell in the first direction being determined to provide a lateral spacing between the outer shell and each of the two side faces of the inner shell perpendicular to the first direction, the flaps being extended in the first direction to cover the two lateral spacings thus formed.
- the outer casing comprises a foam layer of thermal insulation material, the thickness of the spacings and cooling units being between 2 and 12 cm.
- the holding means comprise a narrow case for pressing the cold regulating barrier container against the cold accumulator.
- the case has walls of thin thickness determined to allow the transmission of cold between the cooling unit and the inner casing.
- the holding means comprise male and female complementary parts positioned respectively on the cold barrier container and the cold accumulator.
- a cooling unit is inserted between the flaps of the inner casing and a closure member of the outer casing.
- the cooling unit occupying a spacing formed between a side face of the envelope and a side face of the outer casing, comprises a cold accumulator and at least one substantially flat cold control barrier container.
- the cooling unit occupies a spacing formed between the inner casing and a corner of the outer casing.
- the isothermal packaging device may comprise a transport case.
- the outer part of the body is formed by an open envelope associated with a lid (10) to form an outer envelope (1) of volume adapted according to the quantities of heat-sensitive products (5) to be transported.
- the outer casing (1) may comprise a layer of thermal insulation foam material, for example polyurethane.
- the packaging device also comprises an inner envelope (2) shaped to define a housing (20) for storing thermosensitive products (5).
- the inner (2) and outer (1) envelopes are for example parallelepipedal and comprise a cardboard layer.
- the envelopes (1, 2) comprise an olefin type plastic material, for example polypropylene.
- the volume of the outer casing (1) is determined to allow both to incorporate the housing (20) and to provide at least one spacing (100) on a portion of the periphery of the housing (20), as illustrated in FIG. the figure 1 .
- the inner casing (1) forming a bottom and side walls defining the housing (20) for storage, is for example centered in the outer casing (1) and spaced from at least two side walls of the outer casing (1).
- the spacings (100) defined between the outer casing (2) and the inner casing (1) are intended to each receive at least one removable cooling unit (3) making it possible to keep the products stored in the housing at low temperature ( 20).
- the cover (10) or similar part of the outer casing (1) covering the top of the housing (20) can also incorporate such a spacing (100).
- each cooling unit (3) comprises a cold accumulator (32) or refrigerant briquette, for example of the rigid plastic rectangular pack type that can be frozen and containing a eutectic gel with slow thawing or water, and a cold regulating barrier container (31) filled with a substance of high viscosity, for example with a viscosity of greater than 100 Pa.s or 100000 centipoise.
- the cold regulating barrier container (31) is for example flattened and attached to at least one surface of the cold accumulator (32). This cold regulating barrier container (31), permanently remaining at a temperature strictly greater than 0 ° C.
- each spacing (100) has a thickness (e) limited to between 2 and 12 cm.
- Each spacing (100) may for example receive a cooling unit (3) of dimensions substantially equal to the dimensions of the spacing (100).
- the number of cooling units (3) to be inserted into the spacings may depend on the envisaged transport time.
- the cooling units (3) must make it possible to keep the housing (20) at a temperature greater than 0 ° C, for example between 3 and 8 ° C during a transport time that can be particularly long.
- the cold accumulator (32) contains a gel capable of being frozen at a temperature below -15 ° C and the filling volume of the cold accumulator (32) is 2 to 5 times more high than the filling volume of the cold regulating barrier container (31). The ratio between these volumes is for example 3 to 1.
- the inner casing (2) comprises flaps (21) to form a basket, the flaps (21) closing on the housing (20).
- the parallelepiped formed by the inner envelope (2) may comprise a width dimension (I) to allow for example the insertion of cooling units on either side of the width (I) of the housing (20).
- the inner casing (2) may comprise two flaps (21) oriented along the width (I) and of dimension in length (L) greater than the width (I) of the inner casing (2) to cover the spacings ( 100). These flaps (21) may be provided with handles (22) or equivalent gripping means.
- the inner casing (2) can be formed using a single sheet of cardboard, as shown in FIG. figure 8 .
- the figure 3 illustrates the overlap of the spacings (100) allowed by the flaps (21).
- a cooling unit (3) can then occupy a spacing between the flaps (21) in the closed position and the cover (10) or similar shutter member of the outer casing (1).
- the cold control barrier container (31) acts as a regulator so that the products to be stored are not initially cooled below 0 ° C.
- the regulating barrier container (31) may be of flattened shape and substantially the dimensions of the face of the inner envelope (2) that it covers.
- the cold regulating barrier container (31) is brought together and kept in contact with the cold accumulator by means of holding means.
- these means for holding the cooling unit (3) comprise male and female complementary parts positioned respectively on the cold regulating barrier container (31) and the cold accumulator ( 32).
- a male-female junction is formed by at least two studs (310) protruding from the regulating barrier container (31) which are housed in two cavities (320) of the cold accumulator (32) .
- lugs, pins or pins may be placed on the cold accumulator (32) to be inserted into cavities of the cold regulating barrier (31).
- the Figures 4a and 4b are a cold regulating barrier container (31) flattened provided with two pins (310) disposed on either side of the center of a first face or front of the container (31).
- the distance (a) between the two pins (310) is for example of the order of 4 to 10 cm for a container with a height (H) of between 15 and 30 cm. This distance (a) represents about one third of the height (H) of the container (31) in one embodiment of the invention. Alternatively, the number of pins (310) may be higher.
- At least two cavities (311) of diameter (b) substantially equal to the diameter of the pins (310) are arranged on the second face or the back of the container (31), with the same positioning as that of the pins (310) to allow the assembly between two cold regulating barrier containers (31) identical.
- An asymmetrical positioning between nipples (310) and cavities (311) allowing assembly can also be envisaged.
- the cold barrier resulting from such an assembly, twice as thick, can be matched with a cold accumulator (32) for forming a cooling unit (3).
- a cold accumulator (32) for forming a cooling unit (3).
- the thickness (d2) of the cold regulating barrier container (31) is for example between 15 and 35 mm. In one embodiment of the invention, the width (d1) of the container (31) is at least 80% of the length of the spacing (100) between the inner envelope (2) and the envelope outside (1).
- the interior volume of the cold regulating barrier container (31) can be filled and emptied via an opening (313) closed by a plug.
- the Figures 4c and 4d represent an example of a cold accumulator (32) of flattened form used in the invention.
- Each of the faces of the accumulator (32) comprises at least two cavities (320) to allow pairing and keeping in contact with the cold barrier by inserting the pins (310) into the cavities (320). Alternatively, only one of the faces may be provided with such cavities.
- the width (d3) of the accumulator is substantially equal to the length of the spacings (100) and its thickness (d4) is for example about twice as large as the thickness (d2) of a container (31). cold regulation of the type corresponding to the figure 4a .
- the internal volume of the cold accumulator (32) can be filled and emptied via an opening (321) closed by a plug.
- the cold regulating barrier (31) in contact with the cold accumulator is carried out in a case (30) sufficiently narrow to constantly press the cold regulating barrier container (31) against the cold storage barrier (31).
- cold accumulator (32) can be made of a plastic material, for example a thin polypropylene, and comprise a tab (300) closing the case (30) for maintaining in contiguous position face against face of the elements (31, 32) of the cooling unit (3).
- the thickness of the case (30) is determined to allow the transmission of cold between the cooling unit (3) and the inner casing (2).
- the thickness of the case (30) is for example of the order of 0.8 to 3 mm.
- the cold regulating barrier (31) may consist of a simple plastic bag (310) containing the viscous substance which absorbs the frigories of the accumulator (32).
- cooling units (3) occupy substantially planar spacings parallel to the side faces, it may be envisaged in a different embodiment to provide spacings (100) between the inner casing (2) and a corner of the casing outside (1), as shown in figure 7 .
- the packaging device according to the invention then comprises cooling units (3) arranged at an angle.
- other arrangements and shapes for example with a curved or L-shaped profile, can be envisaged for the realization of the cooling units (3).
- the packaging device allows the implementation of a simple and effective process for packaging heat-sensitive products at a temperature above 0 ° C, for example between 3 and 8 ° C.
- the cold accumulator (32) is previously frozen at a temperature strictly below 0 ° C, and preferably below -15 ° C before being assembled with the cold control barrier (31) which remains at an ambient temperature of the order of 3 to 25 ° C.
- the barrier (31) can be distinguished from the cold accumulator (32) by color marking or other visual signaling, so as to avoid confusion when placing the cooling units (3).
- the user must initially open the flaps (21) to both install the sensitive products (5) in the housing (20), and also install on for example two opposite sides of the units. coolers (3) previously assembled.
- the user can install one or more other cooling units (3) on the flaps (21), as illustrated in FIG. figure 3 and finally closing the outer casing (1).
- This method can be adapted to different housing shapes (20) and to different sizes for the outer shell (1). It allows to transport under usual conditions several doses or bottles of heat-sensitive products.
- a cold regulating barrier (31) in the cooling units (3) makes it possible to cool in a very controlled manner the contents of the storage housing (20), as illustrated with the Figures 9 and 10 .
- the temperature curve of the figure 9 was carried out from a temperature probe placed in a sensitive product stored in a storage package provided only with frozen cold storage accumulators at temperatures of the order of -18 ° C. The beginning of the measurements corresponds to the introduction of the cold accumulators. It can be seen that without a cold barrier, the temperature of the products drops very rapidly below 0 ° C.
- FIG. 9 A same series of measurements carried out with the device according to the invention is presented to the figure 9 .
- the sensitive products are at a low temperature of the order of 4 ° C.
- the measurements begin when the just assembled cooling units (3) are inserted.
- Contact of the inner casing (2) with the cold regulating barrier (31) initially at room temperature causes an initial increase in temperature. This increase lasts about one hour, while the barrier (31) is cooled by the cold accumulator (32).
- the keeping at a substantially constant low temperature is ensured for twenty hours. In this example, it takes at least 40 hours in total for the measured temperature to reach 8 ° C. An even longer time can be achieved by increasing the number of cooling units.
- the packaging process is therefore effective and particularly suitable for the transport of heat-sensitive products.
- One of the advantages of the invention lies in the simplicity of use of the packaging device.
- the packaging process can be easily adapted very quickly, the shape of the housing (20) and the amount of cooling units (3) can be very easily changed.
- the use of envelopes cardboard or other conventional thin packaging material and cold accumulators (32) of conventional type is economically advantageous.
- Another advantage of the invention lies in the fact that with a regulating barrier, the risk of degradation of the product is avoided.
- the method makes it possible to overcome the heavy procedures of freezing / defrosting the batteries according to their use on a case-by-case basis.
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- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Combustion & Propulsion (AREA)
- Physics & Mathematics (AREA)
- Mechanical Engineering (AREA)
- Thermal Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Packages (AREA)
- Auxiliary Devices For And Details Of Packaging Control (AREA)
- Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
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Abstract
Description
La présente invention concerne le domaine de l'emballage isotherme. L'invention concerne plus particulièrement un dispositif d'emballage isotherme destiné aux produits thermosensibles, matières dangereuses, infectieuses, produits biologiquement actifs, etc. utilisés notamment en biotechnologie, chimie, pharmacie ou tout autre type de produit ne tolérant qu'une très faible variation de température.The present invention relates to the field of isothermal packaging. The invention relates more particularly to an isothermal packaging device for thermosensitive products, hazardous materials, infectious substances, biologically active products, etc. used in particular in biotechnology, chemistry, pharmacy or any other type of product tolerating only a very small variation in temperature.
Le document
Il est connu, dans l'art antérieur, un procédé de conditionnement pour des produits thermosensibles à conserver entre 2 et 10 DEG C. Le produit est conservé entre deux ou plusieurs parois intérieures d'isolation thermique formant une cavité intérieure en contact avec des accumulateurs de froid réfrigérés à une température de l'ordre de -20 DEG C. Un flacon de produit est ainsi enveloppé dans un premier conteneur d'isolation, lui-même placé dans une enveloppe plastique rempli de mousse isolante. Un tel mode de conditionnement permet le transport de produits sensibles en conservant la température souhaitée, même dans des environnements froids ou chauds.It is known, in the prior art, a packaging process for thermosensitive products to be stored between 2 and 10 ° C. The product is stored between two or more inner walls of thermal insulation forming an internal cavity in contact with accumulators refrigerated cold at a temperature of the order of -20 ° C. A bottle of product is thus wrapped in a first insulation container, itself placed in a plastic envelope filled with insulating foam. Such a mode of packaging allows the transport of sensitive products while maintaining the desired temperature, even in cold or hot environments.
Toutefois, ce procédé nécessite un volume d'isolation important pour éviter la congélation du produit à conserver. La congélation doit pourtant être évitée car elle altère irréversiblement les propriétés essentielles des produits, en entraînant par exemple une détérioration du principe actif d'une composition pharmaceutique. Par conséquent, un tel système n'est pas adapté pour stocker des volumes importants de produit thermosensible n'acceptant pas la congélation. En effet l'épaisseur de la couche isolante ne doit pas être trop élevée, sous peine de fournir un emballage à l'encombrement et au poids démesuré et engendrer un coût de transport excessif.However, this process requires a large volume of insulation to avoid freezing the product to be preserved. However, freezing must be avoided because it irreversibly alters the essential properties of the products, for example causing a deterioration of the active principle of a pharmaceutical composition. Therefore, such a system is not suitable for storing large volumes of thermosensitive product not accepting freezing. In fact, the thickness of the insulating layer must not be too high, otherwise the packaging will be too bulky and excessively heavy and cause excessive transportation costs.
Le
Il est connu de positionner dans des caisses ou glacières de transport des accumulateurs de froid préalablement congelés à des températures de l'ordre de -20°C. Le moindre contact des produits avec les accumulateurs peut provoquer la congélation des produits. Ce type de méthode exige préalablement de décongeler partiellement les accumulateurs pour ne pas refroidir trop vite le produit à conserver. L'inconvénient majeur de cette méthode est la lourdeur et le caractère peu flexible du protocole de décongélation partielle, peu adapté aux conditions usuelles de transport. De plus, cette méthode prend en compte la durée estimée du transport alors que celle-ci varie fréquemment.It is known to position cold storage accumulators previously frozen at temperatures of the order of -20 ° C. in transport crates or coolers. The slightest contact of the products with the accumulators can cause the freezing of the products. This type of method requires previously to partially defrost the accumulators to not cool too quickly the product to keep. The major disadvantage of this method is the heaviness and the inflexibility of the partial defrosting protocol, poorly adapted to the usual conditions of transport. In addition, this method takes into account the estimated duration of the transport while the latter varies frequently.
Il existe dès lors un besoin pour un procédé de conditionnement dans un emballage de type caisse qui soit adapté pour à la fois subir n'importe quelle condition de transport, et en même temps permettre une très bonne isolation thermique de produits devant être conservés à température sensiblement constante, sans risque de congélation.There is therefore a need for a packaging method in a box type packaging that is adapted to both undergo any transport condition, and at the same time allow very good thermal insulation of products to be kept at temperature. substantially constant, without risk of freezing.
La présente invention a donc pour objet de pallier un ou plusieurs des inconvénients de l'art antérieur en définissant un procédé fiable de conditionnement de produits thermosensibles dans un emballage de transport pour maintenir une température de conservation toujours supérieure à 0°C.The present invention therefore aims to overcome one or more of the disadvantages of the prior art by defining a reliable method of packaging heat-sensitive products in a transport packaging to maintain a conservation temperature always greater than 0 ° C.
A cet effet, l'invention concerne un procédé de conditionnement de produits thermosensibles, au moyen d'un dispositif d'emballage comprenant une enveloppe intérieure conformée pour délimiter un logement de stockage de produits thermosensibles, une enveloppe extérieure ou une caisse de transport de volume déterminé suffisant pour incorporer le logement et définir au moins un espacement localisé sur une partie de la périphérie du logement, ledit procédé étant caractérisé en ce qu'il comporte :
- au moins une étape d'appariement et de maintien, par des moyens de maintien, d'un accumulateur de froid congelé à une température strictement inférieure à 0°C en contact avec un récipient barrière de régulation de froid rempli de substance à indice de viscosité au moins égal à 100 Pa.s et dont la température est supérieure à 3°C pour former une unité de refroidissement amovible apte à occuper un espacement en périphérie du logement,
- une étape d'insertion de l'unité de refroidissement dans ledit espacement avec le récipient barrière de régulation de froid positionné du côté de l'enveloppe intérieure pour former une séparation entre l'accumulateur de froid et l'enveloppe intérieure.
- at least one step of pairing and holding, by holding means, a frozen cold accumulator at a temperature strictly below 0 ° C in contact with a cold regulating barrier container filled with viscosity index substance at least equal to 100 Pa.s and whose temperature is higher than 3 ° C to form a removable cooling unit capable of occupying a spacing at the periphery of the housing,
- a step of inserting the cooling unit in said spacing with the cold regulating barrier container positioned on the side of the inner casing to form a separation between the cold accumulator and the inner casing.
Selon une autre particularité, l'accumulateur de froid contient un volume de 2 à 5 fois plus élevé que le volume contenu dans le récipient barrière de régulation de froid, l'accumulateur de froid étant congelé à une température inférieure à -15°C avant l'étape d'appariement et de maintien en contact tandis que le récipient barrière de régulation de froid est à une température de l'ordre de 3 à 25°C.In another feature, the cold accumulator contains a
Selon une autre particularité de l'invention, l'enveloppe intérieure et l'enveloppe extérieure sont parallélépipédiques, l'enveloppe intérieure étant pourvue de deux rabats orientés selon une première direction horizontale pour former un panier et placée au centre de l'enveloppe extérieure, la dimension de l'enveloppe intérieure selon la première direction étant déterminée pour ménager un espacement latéral entre l'enveloppe extérieure et chacune des deux faces latérales de l'enveloppe intérieure perpendiculaires à la première direction, les rabats étant rallongés suivant la première direction pour recouvrir les deux espacements latéraux ainsi formés.According to another feature of the invention, the inner envelope and the outer envelope are parallelepipedal, the inner envelope being provided with two flaps oriented in a first horizontal direction to form a basket and placed in the center of the outer envelope, the dimension of the inner envelope in the first direction being determined to provide a lateral spacing between the outer shell and each of the two side faces of the inner shell perpendicular to the first direction, the flaps being extended in the first direction to cover the two lateral spacings thus formed.
Selon une autre particularité, l'étape d'appariement et de maintien en contact comprend une jonction de type mâle-femelle entre le récipient barrière de régulation de froid et l'accumulateur de froid, le récipient barrière de régulation de froid étant de forme aplatie.According to another particularity, the step of pairing and keeping in contact comprises a junction of the male-female type between the cold regulating barrier container and the cold accumulator, the cold regulating barrier container being of flattened shape. .
Selon une autre particularité, l'étape d'appariement et de maintien en contact est réalisée dans un étui suffisamment étroit pour plaquer le récipient barrière de régulation de froid contre l'accumulateur de froid, le récipient barrière de régulation de froid étant de forme aplatie.According to another particularity, the step of pairing and keeping in contact is carried out in a holster sufficiently narrow to press the cold regulating barrier container against the cold accumulator, the cold regulating barrier container being of flattened shape. .
Selon une autre particularité de l'invention, une unité de refroidissement est insérée entre les rabats de l'enveloppe intérieure et un élément d'obturation de l'enveloppe extérieure.According to another feature of the invention, a cooling unit is inserted between the flaps of the inner casing and a closure member of the outer casing.
Un objectif de l'invention est également de définir un dispositif d'emballage isotherme pour produits sensibles à la température.An object of the invention is also to define an isothermal packaging device for temperature sensitive products.
A cet effet, l'invention concerne un dispositif d'emballage isotherme pour la mise en oeuvre du procédé de conditionnement de produits thermosensibles selon l'invention, comprenant une enveloppe intérieure conformée pour délimiter un logement de stockage de produits thermosensibles, une enveloppe extérieure ou une caisse de transport de volume déterminé suffisant pour incorporer le logement et définir au moins un espacement localisé sur une partie de la périphérie du logement, caractérisé en ce qu'une unité de refroidissement amovible est logée dans ledit espacement, l'unité de refroidissement comprenant un accumulateur de froid positionné contre l'enveloppe extérieure et un récipient barrière de régulation de froid rempli avec une substance à indice de viscosité au moins égal à 100 Pa.s, le récipient barrière de régulation de froid étant accolé et maintenu en contact par des moyens de maintien avec au moins une surface de l'accumulateur de froid pour former une séparation entre l'enveloppe intérieure et l'accumulateur de froid.For this purpose, the invention relates to an isothermal packaging device for implementing the method of packaging heat-sensitive products according to the invention, comprising an inner envelope shaped to delimit a heat-sensitive product storage compartment, an outer envelope or a transport case of determined volume sufficient to incorporate the housing and define at least one localized spacing on a part of the periphery of the housing, characterized in that a removable cooling unit is housed in said spacing, the cooling unit comprising a cold accumulator positioned against the outer casing and a cold regulating barrier container filled with a substance having a viscosity number of at least 100 Pa.s, the cold regulating barrier container being contiguous and held in contact by holding means with at least one surface of the cold accumulator for sea a separation between the inner envelope and the cold accumulator.
Selon une autre particularité, l'accumulateur de froid contient un gel apte à être congelé à une température inférieure à -15°C, le volume de remplissage de l'accumulateur de froid étant 2 à 5 fois plus élevé que le volume de remplissage du récipient barrière de froid, de façon à maintenir le logement à une température supérieure à 0°C.According to another feature, the cold accumulator contains a gel capable of being frozen at a temperature below -15 ° C., the filling volume of the cold accumulator being 2 to 5 times higher than the volume of the cold accumulator. filling the cold barrier container, so as to maintain the housing at a temperature above 0 ° C.
Selon une autre particularité, l'enveloppe intérieure et l'enveloppe extérieure sont parallélépipédiques, l'enveloppe intérieure étant pourvue de deux rabats orientés selon une première direction horizontale pour former un panier et placée au centre de l'enveloppe extérieure, la dimension de l'enveloppe intérieure selon la première direction étant déterminée pour ménager un espacement latéral entre l'enveloppe extérieure et chacune des deux faces latérales de l'enveloppe intérieure perpendiculaires à la première direction, les rabats étant rallongés suivant la première direction pour recouvrir les deux espacements latéraux ainsi formés.According to another feature, the inner envelope and the outer envelope are parallelepipedal, the inner envelope being provided with two flaps oriented in a first horizontal direction to form a basket and placed in the center of the outer envelope, the dimension of the inner shell in the first direction being determined to provide a lateral spacing between the outer shell and each of the two side faces of the inner shell perpendicular to the first direction, the flaps being extended in the first direction to cover the two lateral spacings thus formed.
Selon une autre particularité, l'enveloppe extérieure comprend une couche de mousse de matériau d'isolation thermique, l'épaisseur des espacements et des unités de refroidissement étant comprise entre 2 et 12 cm.According to another feature, the outer casing comprises a foam layer of thermal insulation material, the thickness of the spacings and cooling units being between 2 and 12 cm.
Selon une autre particularité, les moyens de maintien comprennent un étui étroit pour plaquer le récipient barrière de régulation de froid contre l'accumulateur de froid.According to another feature, the holding means comprise a narrow case for pressing the cold regulating barrier container against the cold accumulator.
Selon une autre particularité, l'étui a des parois d'épaisseur mince déterminée pour permettre la transmission de froid entre l'unité de refroidissement et l'enveloppe intérieure.According to another feature, the case has walls of thin thickness determined to allow the transmission of cold between the cooling unit and the inner casing.
Selon une autre particularité, les moyens de maintien comprennent des parties complémentaires mâle et femelle positionnées respectivement sur le récipient barrière de froid et l'accumulateur de froid.According to another feature, the holding means comprise male and female complementary parts positioned respectively on the cold barrier container and the cold accumulator.
Selon une autre particularité de l'invention, une unité de refroidissement est insérée entre les rabats de l'enveloppe intérieure et un élément d'obturation de l'enveloppe extérieure.According to another feature of the invention, a cooling unit is inserted between the flaps of the inner casing and a closure member of the outer casing.
Selon une autre particularité de l'invention, l'unité de refroidissement, occupant un espacement formé entre une face latérale de l'enveloppe intérieure et une face latérale de l'enveloppe extérieure, comprend un accumulateur de froid et au moins un récipient barrière de régulation de froid sensiblement plan.According to another feature of the invention, the cooling unit, occupying a spacing formed between a side face of the envelope and a side face of the outer casing, comprises a cold accumulator and at least one substantially flat cold control barrier container.
Selon une autre particularité, l'unité de refroidissement occupe un espacement formé entre l'enveloppe intérieure et un coin de l'enveloppe extérieure.According to another feature, the cooling unit occupies a spacing formed between the inner casing and a corner of the outer casing.
L'invention, avec ses caractéristiques et avantages, ressortira plus clairement à la lecture de la description faite en référence aux dessins annexés dans lesquels :
- la
figure 1 représente une vue en coupe d'un mode de réalisation d'une caisse d'emballage isotherme selon la présente invention, - la
figure 2 présente une vue en perspective éclatée de différents éléments constitutifs de l'intérieur d'un dispositif d'emballage isotherme selon l'invention, - la
figure 3 représente une vue en perspective un agencement des éléments insérés dans l'enveloppe extérieure du dispositif d'emballage isotherme selon l'invention, - la
figure 4 représente un exemple d'unité de refroidissement avec barrière de régulation de froid pouvant être utilisée dans le dispositif selon l'invention, - la
figure 4a et 4b montrent une vue de dessus, respectivement une vue en coupe selon un plan vertical d'un exemple de récipient barrière de régulation de froid utilisé dans l'invention, - la
figure 4c et 4d montrent une vue de dessus, respectivement une vue en coupe selon un plan vertical d'un exemple d'accumulateur de froid utilisé dans l'invention, - la
figure 4e représente un exemple d'assemblage d'une unité de refroidissement avec deux récipients barrières de régulation de froid permis par l'invention, - la
figure 5 représente une variante de réalisation d'unité de refroidissement pouvant être utilisée dans l'invention, - la
figure 6 représente un exemple de barrière de régulation de froid utilisable dans l'invention, - la
figure 7 représente une vue en coupe selon un plan horizontal d'une variante de réalisation d'un dispositif d'emballage suivant l'invention, - la
figure 8 représente un mode de réalisation de l'enveloppe intérieure utilisée dans l'invention, - la
figure 9 illustre l'évolution de température mesurée dans un produit sensible placé dans un emballage de stockage pourvu uniquement d'accumulateurs de froid, à partir du moment d'insertion des accumulateurs, - la
figure 10 illustre l'évolution de température d'un produit sensible disposé dans le logement d'un dispositif d'emballage selon l'invention, mesurée après insertion des unités de refroidissement dans le dispositif.
- the
figure 1 represents a sectional view of an embodiment of an insulated packaging box according to the present invention, - the
figure 2 shows an exploded perspective view of various constituent elements of the interior of an isothermal packaging device according to the invention, - the
figure 3 represents a perspective view of an arrangement of the elements inserted in the outer casing of the isothermal packaging device according to the invention, - the
figure 4 represents an example of cooling unit with cold control barrier that can be used in the device according to the invention, - the
Figure 4a and 4b show a top view, respectively a sectional view along a vertical plane of an example of cold control barrier container used in the invention, - the
Figure 4c and 4d show a view from above, respectively a sectional view along a vertical plane of an example of a cold accumulator used in the invention, - the
figure 4e represents an example of assembly of a cooling unit with two refrigeration barrier containers allowed by the invention, - the
figure 5 represents an alternative embodiment of a cooling unit that can be used in the invention, - the
figure 6 represents an example of a cold regulating barrier that can be used in the invention, - the
figure 7 represents a sectional view along a horizontal plane of an alternative embodiment of a packaging device according to the invention, - the
figure 8 represents an embodiment of the inner envelope used in the invention, - the
figure 9 illustrates the temperature evolution measured in a sensitive product placed in a storage package provided only with cold accumulators, from the moment of insertion of the accumulators, - the
figure 10 illustrates the temperature evolution of a sensitive product disposed in the housing of a packaging device according to the invention, measured after insertion of the cooling units in the device.
L'invention va être à présent décrite en référence à la
Comme représenté à la
Le volume de l'enveloppe extérieure (1) est déterminé pour permettre à la fois d'incorporer le logement (20) et ménager au moins un espacement (100) situé sur une partie de la périphérie du logement (20), comme illustré dans la
Dans le mode de réalisation préféré de l'invention, chaque unité de refroidissement (3) comprend un accumulateur de froid (32) ou briquette réfrigérante, par exemple du type pack rectangulaire en plastique rigide pouvant être congelé et contenant un gel eutectique à décongélation lente ou de l'eau, et un récipient barrière de régulation de froid (31) rempli avec une substance de forte viscosité, par exemple de viscosité supérieure à 100 Pa.s ou 100000 centipoises. Le récipient barrière de régulation de froid (31) est par exemple aplati et accolé à au moins une surface de l'accumulateur de froid (32). Ce récipient barrière de régulation de froid (31), restant en permanence à une température strictement supérieure à 0°C et par exemple supérieure à 3 ou 4°C, sert à former après insertion dans un des espacements (100) une séparation entre l'enveloppe intérieure (2) et l'accumulateur de froid (32). Cet accumulateur (32) est positionné contre l'enveloppe extérieure (1). Dans le mode de réalisation de la
Les unités de refroidissement (3) doivent permettre de maintenir le logement (20) à une température supérieure à 0°C, par exemple comprise entre 3 et 8°C pendant une durée de transport qui peut être particulièrement longue. Pour parvenir à ce résultat, l'accumulateur de froid (32) contient un gel apte à être congelé à une température inférieure à -15°C et le volume de remplissage de l'accumulateur de froid (32) est 2 à 5 fois plus élevé que le volume de remplissage du récipient barrière de régulation de froid (31). Le ratio entre ces volumes est par exemple de 3 pour 1.The cooling units (3) must make it possible to keep the housing (20) at a temperature greater than 0 ° C, for example between 3 and 8 ° C during a transport time that can be particularly long. To achieve this result, the cold accumulator (32) contains a gel capable of being frozen at a temperature below -15 ° C and the filling volume of the cold accumulator (32) is 2 to 5 times more high than the filling volume of the cold regulating barrier container (31). The ratio between these volumes is for example 3 to 1.
L'invention va être à présent décrite en référence aux
Dans le mode de réalisation des
Au cours du transport dans le dispositif d'emballage, le récipient barrière de régulation de froid (31) joue le rôle de régulateur pour que les produits à conserver ne soient pas initialement refroidis en dessous de 0°C. Dans une forme de réalisation de l'invention, pour assurer cette fonction, le récipient barrière de régulation (31) peut être de forme aplatie et sensiblement aux dimensions de la face de l'enveloppe intérieure (2) qu'il recouvre. Pour rendre homogène la transmission de froid, le récipient barrière de régulation de froid (31) est accolé et maintenu en contact avec l'accumulateur de froid à l'aide de moyens de maintien. Dans un mode de réalisation de l'invention, ces moyens de maintien de l'unité de refroidissement (3) comprennent des parties complémentaires mâle et femelle positionnées respectivement sur le récipient barrière de régulation de froid (31) et l'accumulateur de froid (32). Comme illustré à la
Les
L'épaisseur (d2) du récipient barrière de régulation de froid (31) est par exemple comprise entre 15 et 35 mm. Dans un mode de réalisation de l'invention, la largeur (d1) du récipient (31) est au moins égale à 80% de la longueur de l'espacement (100) ménagé entre l'enveloppe intérieure (2) et l'enveloppe extérieure (1). Le volume intérieur du récipient barrière de régulation de froid (31) peut être rempli et vidé via une ouverture (313) fermée par un bouchon.The thickness (d2) of the cold regulating barrier container (31) is for example between 15 and 35 mm. In one embodiment of the invention, the width (d1) of the container (31) is at least 80% of the length of the spacing (100) between the inner envelope (2) and the envelope outside (1). The interior volume of the cold regulating barrier container (31) can be filled and emptied via an opening (313) closed by a plug.
Les
Dans une variante, le maintien en contact de la barrière de régulation de froid (31) avec l'accumulateur de froid est effectué dans un étui (30) suffisamment étroit pour constamment plaquer le récipient barrière de régulation de froid (31) contre l'accumulateur de froid (32). Comme illustré à la
Tandis que dans le mode de réalisation de la
On comprend donc que le dispositif d'emballage selon l'invention permet la mise en oeuvre d'un processus simple et efficace de conditionnement de produits thermosensibles à une température supérieure à 0°C, par exemple comprise entre 3 et 8°C. Pour cela, l'accumulateur de froid (32) est préalablement congelé à une température strictement inférieure à 0°C, et de préférence inférieure à -15°C avant d'être assemblé avec la barrière de régulation de froid (31) qui reste à une température ambiante de l'ordre de 3 à 25°C. La barrière (31) peut être distinguée de l'accumulateur de froid (32) par un marquage de couleur ou autre signalisation visuelle, de façon à éviter toute confusion lors de la mise en place des unités de refroidissement (3). Dans un mode de réalisation de l'invention, l'utilisateur doit initialement ouvrir les rabats (21) pour à la fois installer les produits sensibles (5) dans le logement (20), et également installer sur par exemple deux côtés opposés des unités de refroidissement (3) préalablement assemblées. En option après repliement des rabats (21), l'utilisateur peut installer une ou plusieurs autres unités de refroidissement (3) sur les rabats (21), comme illustré à la
L'invention va à présent être décrite en liaison avec les
Ce procédé peut être adapté à différentes formes de logement (20) et à différentes tailles pour l'enveloppe extérieure (1). Il permet de transporter dans des conditions usuelles plusieurs doses ou flacons de produits thermosensibles. De plus l'utilisation d'une barrière de régulation de froid (31) dans les unités de refroidissement (3) permet de refroidir de manière très régulée le contenu du logement (20) de stockage, comme illustré avec les
Une même série de mesures effectuée avec le dispositif selon l'invention est présentée à la
Un des avantages de l'invention réside dans la simplicité d'utilisation du dispositif d'emballage. Le procédé de conditionnement peut être aisément adapté de manière très rapide, la forme du logement (20) et la quantité d'unités de refroidissement (3) pouvant être très facilement modifiée. De plus, l'utilisation d'enveloppes en carton ou autre matériau usuel d'emballage de faible épaisseur ainsi que d'accumulateurs de froid (32) de type classique est économiquement avantageuse.One of the advantages of the invention lies in the simplicity of use of the packaging device. The packaging process can be easily adapted very quickly, the shape of the housing (20) and the amount of cooling units (3) can be very easily changed. In addition, the use of envelopes cardboard or other conventional thin packaging material and cold accumulators (32) of conventional type is economically advantageous.
Un autre des avantages de l'invention réside dans le fait qu'avec une barrière de régulation, on évite le risque de dégradation du produit. De plus, le procédé permet de s'affranchir des lourdes procédures consistant à congeler/décongeler au cas par cas les accumulateurs selon leur utilisation.Another advantage of the invention lies in the fact that with a regulating barrier, the risk of degradation of the product is avoided. In addition, the method makes it possible to overcome the heavy procedures of freezing / defrosting the batteries according to their use on a case-by-case basis.
Il doit être évident pour les personnes versées dans l'art que la présente invention permet des modes de réalisation sous de nombreuses autres formes spécifiques sans l'éloigner du domaine d'application de l'invention comme revendiqué. Par conséquent, les présents modes de réalisation doivent être considérés à titre d'illustration, mais peuvent être modifiés dans le domaine défini par la portée des revendications jointes, et l'invention ne doit pas être limitée aux détails donnés ci-dessus.It should be obvious to those skilled in the art that the present invention allows embodiments in many other specific forms without departing from the scope of the invention as claimed. Therefore, the present embodiments should be considered by way of illustration, but may be modified within the scope defined by the scope of the appended claims, and the invention should not be limited to the details given above.
Claims (16)
- Method of packaging heat-sensitive products (5) by means of a container comprising an inner shell (2) shaped in order to delimit a compartment (20) for storage of heat-sensitive products, an outer shell (1) or transport casing having a defined volume sufficient for inclusion of the compartment (20) and to define at least one localised space (100) on a part of the periphery of the compartment (20), the method being characterised in that it includes:- at least one step of pairing and of maintaining, by maintaining means, cold pack (32) frozen to a temperature strictly below 0°C in contact with a cold regulation barrier container (31) filled with a substance having a viscosity index higher than or equal to 100 Pa.s and a temperature strictly higher than 3 °C in order to form a removable cooling unit (3) capable of occupying the space (100) at the periphery of the compartment (20),- a step of insertion of the coaling unit (3) into the said space (100) with the cold regulation barrier container (31) positioned on the side of the inner shell (2) in order to form a separation between the cold pack (32) and the inner shell (2).
- Method of packaging as claimed in Claim 1, wherein the cold pack (32) contains a volume 2 to 5 times higher than the volume contained in the cold regulation barrier container (31), the cold pack (32) being frozen to a temperature below -15 °C before the step or pairing and maintaining in contact whilst the cold regulation barrier container (31) is at a temperature of the order of 3 to 25 °C.
- Method of packaging as claimed in Claim 1 or Claims 2, wherein the inner shell (2) and the outer shell (1) are parallelepipedal, the inner shell (2) being provided with two flaps (21) oriented in a first horizontal direction in order to form a basket and placed in the centre of the outer shell (1) the dimension (I) of the inner shell (2) in the first direction being defined in order to provide a lateral spacing between the outer shell (1) and each of the two lateral faces of the inner shell (1) perpendicular to the first direction, the flaps (21) being elongated in a first direction in order to cover the two lateral spaces thus formed.
- Method of packaging as claimed in any one of Claims 1 to 3, wherein the step of pairing and maintaining in contact comprises a junction of the male-female type between the cold regulation barrier container and the cold pack, the cold regulation barrier container (31) being of flattened shape.
- Method of packaging as claimed in any one of Claims 1 to 3, wherein the step of pairing and maintaining in contact is carried out in a narrow case (30) in order to apply the cold regulation barrier container (31) against the cold pack (32), the cold regulation barrier container (31) being of flattened shape.
- Method of packaging as claimed in any one of Claims 3 to 5, wherein a cooling unit (3) is inserted between the flaps (21) of the inner shell (2) and a closure element (10) of the outer shell (1).
- Isothermal container for carrying out the method of packaging heat-sensitive products (5) as claimed in any one of Claims 1 to 6, comprising an inner shell (2) shaped in order to delimit a compartment (20) for storage of heat-sensitive products (5), an outer shell (1) or transport casing having a defined volume sufficient for inclusion of the compartment (20) and to define at least one localised space (100) on a part of the periphery of the compartment (20), characterised in that a removable cooling unit (3) is accommodated in the said space (100), the cooling unit (3) comprising a cold pack (32) positioned against the outer shell (1) and a cold regulation barrier container (31) filled with a substance having a viscosity index higher than or equal to 100 Pa.s, the cold regulation barrier container (31) being attached and maintained in contact by maintaining means with at least one surface of the cold pack (32) in order to form a separation between the inner shell (2) and the cold pack (32).
- Isothermal container as claimed in Claim 7, wherein the cold pack (32) contains a gel capable of being frozen to a temperature below -15 °C, the filling volume of the cold pack (32) being 2 to 5 times higher than the filling volume of the cold regulation barrier container (31), in such a way as to main the compartment (20) at a temperature higher than 0 °C.
- Isothermal container as claimed in Claim 7 or Claim 8, wherein the inner shell (2) and the outer shell (1) are parallelepipedal, the inner shell (2) being provided with two flaps (21) oriented in a first horizontal direction in order to form a basket and placed in the centre of the outer shell (1) the dimension of the inner shell (2) in the first direction being defined in order to provide a lateral spacing between the outer shell (1) and each of the two lateral faces or the inner shell (2) perpendicular to the first direction, the flaps (21) being elongated in a first direction in order to cover the two lateral spaces thus formed.
- Isothermal container as claimed in any one of Claims 7 to 9, wherein the outer shell (1) comprises a layer of foam or thermal insulating material, the thickness (e) or the spaces (100) and of the cooling units (3) being between 2 and 12 cm.
- Isothermal container as claimed in any one of Claims 7 to 10, wherein the maintaining means comprise a narrow case (30) in order to apply the cold regulation barrier container (31) against the cold pack (32).
- Isothermal container as claimed in Claim 11, wherein the case has thin walls of a defined thickness in order to enable the transmission of cold between the cooling unit (3) and the inner shell (2).
- Isothermal container as claimed in any one of Claims 7 to 12, wherein the maintaining means comprise complimentary male and female parts (310, 320) positioned respectively on the cold regulation barrier container (31) and the cold pack (32).
- Isothermal container as claimed in any one of Claims 9 to 13, wherein a cooling unit (3) is inserted between the flaps (21) of the inner shell (2) and a closure element (10) of the outer shell (1).
- Isothermal container as claimed in any one of Claims 7 to 14, wherein the cooling unit (3), occupying a space formed between a lateral face of the inner shell (2) and a lateral face of the outer shell (1), comprises a cold pack (32) and at least one substantially planar cold regulation barrier container (31).
- Isothermal container as claimed in any one of Claims 7 to 14, wherein the cooling unit (3) occupies a space (100) formed between the inner shell (2) and a corner of the outer shell (1).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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FR0305697A FR2854875B1 (en) | 2003-05-12 | 2003-05-12 | ISOTHERMIC PACKAGING DEVICE FOR TEMPERATURE SENSITIVE PRODUCTS AND METHOD FOR MANUFACTURING THE SAME |
FR0305697 | 2003-05-12 |
Publications (2)
Publication Number | Publication Date |
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EP1477751A1 EP1477751A1 (en) | 2004-11-17 |
EP1477751B1 true EP1477751B1 (en) | 2010-09-29 |
Family
ID=33017162
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP04291214A Expired - Lifetime EP1477751B1 (en) | 2003-05-12 | 2004-05-12 | Isothermal package for heat sensitive products and method for its production |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1477751B1 (en) |
AT (1) | ATE483143T1 (en) |
DE (1) | DE602004029306D1 (en) |
ES (1) | ES2352790T3 (en) |
FR (1) | FR2854875B1 (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2875000B1 (en) * | 2004-09-08 | 2007-04-27 | Daniel Cholet | SELF-RELEASABLE BERLINGOT COMPOSED OF AN ICE POCKET SURROUNDED BY MULTIPLE THERMAL PROTECTION BARRIERS |
EP2053325A1 (en) * | 2007-10-23 | 2009-04-29 | Deutsche Post AG | Collapsible container package; method for packing temperature sensitive goods and container pooling system |
EP2098809B1 (en) | 2008-03-06 | 2011-02-16 | Eutecma GmbH | Cooling element with excessive cooling protection |
FR2935471A1 (en) * | 2008-09-02 | 2010-03-05 | Francois Ducrocq | Hollow eutectic gel shell for use in e.g. cooling device to preserve chocolate, has semi-shells that are adjustable for being interlocked with each other, filled with cooling material such as eutectic gel, and hermetically closed |
JP5402416B2 (en) * | 2009-09-02 | 2014-01-29 | 玉井化成株式会社 | Constant temperature storage container and transportation method |
FR2974711B1 (en) * | 2011-05-05 | 2013-06-21 | Soler Jacques Costa | DEVICE FOR PROTECTING AND PRESERVING THE MEAT PINS AT GOOD TEMPERATURE AFTER THE USE AND STOPPING OF THE PINS |
CN102419046A (en) * | 2011-12-23 | 2012-04-18 | 海尔集团公司 | Freezer with cold regenerator |
JP6498879B2 (en) * | 2014-06-30 | 2019-04-10 | トッパン・フォームズ株式会社 | Storage container |
JP5959705B1 (en) * | 2015-09-09 | 2016-08-02 | 積水化成品工業株式会社 | Method for using cold storage heat material, package, and cold storage heat material |
EP3141847A1 (en) * | 2015-09-10 | 2017-03-15 | REWE Digital GmbH | Transport container for refrigerated and/or frozen goods and method and apparatus for preparing a transport container for use |
DE102015117161A1 (en) * | 2015-10-08 | 2017-04-13 | Güdel Group AG | Transport container for transporting chilled goods |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4530816A (en) * | 1983-06-15 | 1985-07-23 | Hamilton Farm | Method and device for cooling, preserving and safely transporting biological material |
US4656840A (en) * | 1985-11-29 | 1987-04-14 | Gott Corporation | Container for freezable liquid |
WO1989009913A1 (en) * | 1988-04-12 | 1989-10-19 | John Kenneth Bethune | Coolant pack |
US5435573A (en) | 1993-04-13 | 1995-07-25 | Visioneering International, Inc. | Wireless remote control and position detecting system |
JPH10111057A (en) * | 1996-10-08 | 1998-04-28 | Inoac Corp | Cold insulating material for preventing vegetables and fluts from getting frost bitten |
CA2337632C (en) * | 1997-11-28 | 2007-05-01 | Pharm-Aid Inc. | Container arrangement and method for transporting equine semen |
US5899088A (en) * | 1998-05-14 | 1999-05-04 | Throwleigh Technologies, L.L.C. | Phase change system for temperature control |
AUPP560398A0 (en) | 1998-08-31 | 1998-09-24 | Laby, Ralph Henry | Cool keeping transport arrangement and method |
GB9915265D0 (en) * | 1999-07-01 | 1999-09-01 | Kryotrans Ltd | Thermally insulated container |
JP2001061882A (en) * | 1999-08-27 | 2001-03-13 | Moritomo Tsusho Kk | Cold reserving bag |
US6325281B1 (en) * | 2000-03-30 | 2001-12-04 | Polyfoam Packers Corporation | Thermally insulating shipping system |
GB2383402A (en) * | 2001-08-10 | 2003-06-25 | Adrian Peter Copeland | Heat-insulated container |
-
2003
- 2003-05-12 FR FR0305697A patent/FR2854875B1/en not_active Expired - Fee Related
-
2004
- 2004-05-12 AT AT04291214T patent/ATE483143T1/en not_active IP Right Cessation
- 2004-05-12 ES ES04291214T patent/ES2352790T3/en not_active Expired - Lifetime
- 2004-05-12 DE DE602004029306T patent/DE602004029306D1/en not_active Expired - Lifetime
- 2004-05-12 EP EP04291214A patent/EP1477751B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1477751A1 (en) | 2004-11-17 |
FR2854875B1 (en) | 2005-10-14 |
FR2854875A1 (en) | 2004-11-19 |
DE602004029306D1 (en) | 2010-11-11 |
ATE483143T1 (en) | 2010-10-15 |
ES2352790T3 (en) | 2011-02-23 |
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