FR2804971B1 - Adn codant une acetohydroxyacide synthase, bacterie le contenant et procede de production de l-valine par culture de cette bacterie - Google Patents
Adn codant une acetohydroxyacide synthase, bacterie le contenant et procede de production de l-valine par culture de cette bacterieInfo
- Publication number
- FR2804971B1 FR2804971B1 FR0101070A FR0101070A FR2804971B1 FR 2804971 B1 FR2804971 B1 FR 2804971B1 FR 0101070 A FR0101070 A FR 0101070A FR 0101070 A FR0101070 A FR 0101070A FR 2804971 B1 FR2804971 B1 FR 2804971B1
- Authority
- FR
- France
- Prior art keywords
- same
- acetohydroxyacide
- synthase
- valine
- culturing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2000101678/13A RU2209246C2 (ru) | 2000-01-26 | 2000-01-26 | Малая субъединица изозима iii и изозим iii синтетазы ацетогидроксикислот из escherichia coli, фрагмент днк (варианты), штамм бактерии escherichia coli - продуцент l-валина (варианты) и способ получения l-валина |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2804971A1 FR2804971A1 (fr) | 2001-08-17 |
FR2804971B1 true FR2804971B1 (fr) | 2004-04-23 |
Family
ID=20229713
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0101070A Expired - Lifetime FR2804971B1 (fr) | 2000-01-26 | 2001-01-26 | Adn codant une acetohydroxyacide synthase, bacterie le contenant et procede de production de l-valine par culture de cette bacterie |
Country Status (5)
Country | Link |
---|---|
US (1) | US6737255B2 (fr) |
JP (1) | JP2001231584A (fr) |
CN (1) | CN1182246C (fr) |
FR (1) | FR2804971B1 (fr) |
RU (1) | RU2209246C2 (fr) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2144564C1 (ru) * | 1998-10-13 | 2000-01-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | ФРАГМЕНТ ДНК rhtB, КОДИРУЮЩИЙ СИНТЕЗ БЕЛКА RhtB, ПРИДАЮЩЕГО УСТОЙЧИВОСТЬ К L-ГОМОСЕРИНУ БАКТЕРИЯМ ESCHERICHIA COLI, И СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ |
US20060040364A1 (en) * | 1998-10-13 | 2006-02-23 | Livshits Vitaly A | DNA coding for a protein which imparts L-homoserine resistance to Escherichia coli bacterium, and a method for producing L-amino acids |
RU2175351C2 (ru) | 1998-12-30 | 2001-10-27 | Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО "АГРИ") | Фрагмент днк из escherichia coli, определяющий повышенную продукцию l-аминокислот (варианты), и способ получения l-аминокислот |
RU2212447C2 (ru) * | 2000-04-26 | 2003-09-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Штамм escherichia coli - продуцент аминокислоты (варианты) и способ получения аминокислот (варианты) |
RU2208640C2 (ru) * | 2000-07-06 | 2003-07-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | СПОСОБ ПОЛУЧЕНИЯ L-АРГИНИНА, ШТАММ Escherichia coli - ПРОДУЦЕНТ L-АРГИНИНА |
RU2229513C2 (ru) * | 2001-11-23 | 2004-05-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Способ получения l-аминокислот, штамм escherichia coli - продуцент l-аминокислоты (варианты) |
EP1491634A1 (fr) * | 2003-06-26 | 2004-12-29 | Degussa AG | Mutants de synthétase d' acide acétohydroxy résistents au feedback |
US7300776B2 (en) * | 2004-04-26 | 2007-11-27 | Ajinomoto Co., Inc. | L-amino acid-producing bacterium and a method for producing L-amino acid |
RU2315807C2 (ru) * | 2004-09-10 | 2008-01-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | СПОСОБ ПОЛУЧЕНИЯ НОРЛЕЙЦИНА И НОРВАЛИНА С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ РОДА Escherichia, В КОТОРОЙ ВСЕ СИНТАЗЫ АЦЕТОГИДРОКСИКИСЛОТ ИНАКТИВИРОВАНЫ |
RU2355763C2 (ru) * | 2006-09-13 | 2009-05-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | Мутантная ацетолактатсинтаза и способ продукции разветвленных l-аминокислот |
KR100832740B1 (ko) * | 2007-01-17 | 2008-05-27 | 한국과학기술원 | 분지쇄 아미노산 생성능이 개선된 변이 미생물 및 이를이용한 분지쇄 아미노산의 제조방법 |
CN101962664A (zh) * | 2010-11-02 | 2011-02-02 | 天津科技大学 | 一种高效生产l-缬氨酸的发酵工艺 |
WO2017194696A1 (fr) | 2016-05-12 | 2017-11-16 | Danmarks Tekniske Universitet | Cellules bactériennes à tolérance améliorée pour l'acide isobutyrique |
JP7447810B2 (ja) | 2018-05-23 | 2024-03-12 | 味の素株式会社 | 腸内細菌科を用いたトリペプチドγ-GLU-VAL-GLYの製造方法 |
US20210403927A1 (en) * | 2018-12-12 | 2021-12-30 | Utilization Of Carbon Dioxide Institute Co., Ltd. | A Recombinant of Hydrogenophilus Bacterium with Enhanced Ability to Produce Valine |
CN114457122B (zh) | 2020-05-13 | 2023-06-20 | 安徽华恒生物科技股份有限公司 | 生产l-缬氨酸的重组微生物及构建方法、应用 |
CN113278641B (zh) | 2020-05-27 | 2022-06-21 | 安徽华恒生物科技股份有限公司 | 生产l-缬氨酸的重组大肠杆菌、其构建方法及其应用 |
CN113278568B (zh) | 2020-05-27 | 2022-10-21 | 安徽华恒生物科技股份有限公司 | 生产l-缬氨酸的重组大肠杆菌及其应用 |
CN116555153B (zh) * | 2023-07-04 | 2023-09-29 | 黑龙江伊品生物科技有限公司 | 一种用于生产l-缬氨酸的大肠杆菌的构建方法与应用 |
CN116555151B (zh) * | 2023-07-04 | 2023-10-17 | 黑龙江伊品生物科技有限公司 | 产l-缬氨酸工程菌及构建方法与应用 |
CN116555152B (zh) * | 2023-07-04 | 2023-10-20 | 黑龙江伊品生物科技有限公司 | 大肠杆菌及其构建方法与在生产l-缬氨酸中的应用 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2748418B2 (ja) | 1988-08-03 | 1998-05-06 | 味の素株式会社 | 組換えdna、該組換えdnaを有する微生物 |
US5976843A (en) | 1992-04-22 | 1999-11-02 | Ajinomoto Co., Inc. | Bacterial strain of Escherichia coli BKIIM B-3996 as the producer of L-threonine |
DE3891417T1 (de) | 1988-10-25 | 1991-01-10 | Vnii Genetiki Selektsii Promy | Stamm der bakterien escherichia coli bkiim b-3996, produziert von l-threonin |
US5705371A (en) | 1990-06-12 | 1998-01-06 | Ajinomoto Co., Inc. | Bacterial strain of escherichia coli BKIIM B-3996 as the producer of L-threonine |
DE3942947A1 (de) | 1989-12-23 | 1991-06-27 | Forschungszentrum Juelich Gmbh | Verfahren zur herstellung von l-isoleucin und dafuer geeignete mikroorganismen und rekombinante dna |
US5534421A (en) | 1991-05-30 | 1996-07-09 | Ajinomoto Co., Inc. | Production of isoleucine by escherichia coli having isoleucine auxotrophy and no negative feedback inhibition of isoleucine production |
US6132999A (en) | 1992-09-21 | 2000-10-17 | Ajinomoto Co., Inc. | L-threonine-producing microbacteria and a method for the production of L-threonine |
US5888783A (en) | 1994-08-30 | 1999-03-30 | Ajinomoto Co., Inc. | Methods for producing L-valine and L-leucine |
-
2000
- 2000-01-26 RU RU2000101678/13A patent/RU2209246C2/ru active
-
2001
- 2001-01-18 US US09/761,782 patent/US6737255B2/en not_active Expired - Lifetime
- 2001-01-19 JP JP2001011229A patent/JP2001231584A/ja not_active Withdrawn
- 2001-01-26 FR FR0101070A patent/FR2804971B1/fr not_active Expired - Lifetime
- 2001-01-31 CN CNB011033312A patent/CN1182246C/zh not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US20020037562A1 (en) | 2002-03-28 |
JP2001231584A (ja) | 2001-08-28 |
FR2804971A1 (fr) | 2001-08-17 |
CN1310233A (zh) | 2001-08-29 |
CN1182246C (zh) | 2004-12-29 |
US6737255B2 (en) | 2004-05-18 |
RU2209246C2 (ru) | 2003-07-27 |
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Legal Events
Date | Code | Title | Description |
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PLFP | Fee payment |
Year of fee payment: 16 |
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PLFP | Fee payment |
Year of fee payment: 17 |
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PLFP | Fee payment |
Year of fee payment: 18 |
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PLFP | Fee payment |
Year of fee payment: 20 |