FR2567540B1 - Procede de preparation d'un interferon leucocytaire humain alpha-2 - Google Patents

Procede de preparation d'un interferon leucocytaire humain alpha-2

Info

Publication number
FR2567540B1
FR2567540B1 FR8510816A FR8510816A FR2567540B1 FR 2567540 B1 FR2567540 B1 FR 2567540B1 FR 8510816 A FR8510816 A FR 8510816A FR 8510816 A FR8510816 A FR 8510816A FR 2567540 B1 FR2567540 B1 FR 2567540B1
Authority
FR
France
Prior art keywords
leukocyta
human
preparation
interferon alpha
interferon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8510816A
Other languages
English (en)
Other versions
FR2567540A1 (fr
Inventor
V G Debabov
J D Tsygankov
A J Chistoserdov
E D Sverdlov
L S Izotova
S V Kostrov
V E Sterkin
V P Kuznetsov
S V Belyaev
G S Monastyrskaya
I S Salomatina
G M Dolganov
S G Arsenian
S A Tsarev
J I Kozlov
A Y Strongin
V I Ogarkov
J A Ovchinnikov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INST GENETIKI I SELEKTSII
Original Assignee
INST GENETIKI I SELEKTSII
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INST GENETIKI I SELEKTSII filed Critical INST GENETIKI I SELEKTSII
Publication of FR2567540A1 publication Critical patent/FR2567540A1/fr
Application granted granted Critical
Publication of FR2567540B1 publication Critical patent/FR2567540B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/78—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Pseudomonas
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/811—Interferon
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y10S930/142—Interferon

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FR8510816A 1984-07-13 1985-07-15 Procede de preparation d'un interferon leucocytaire humain alpha-2 Expired FR2567540B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU843757952A SU1364343A1 (ru) 1984-07-13 1984-07-13 Способ получени человеческого лейкоцитарного интерферона альфа-2

Publications (2)

Publication Number Publication Date
FR2567540A1 FR2567540A1 (fr) 1986-01-17
FR2567540B1 true FR2567540B1 (fr) 1988-10-14

Family

ID=21125646

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8510816A Expired FR2567540B1 (fr) 1984-07-13 1985-07-15 Procede de preparation d'un interferon leucocytaire humain alpha-2

Country Status (12)

Country Link
US (1) US4680260A (fr)
JP (1) JPS6156093A (fr)
BG (1) BG46981A1 (fr)
CA (1) CA1264294A (fr)
CH (1) CH666051A5 (fr)
DE (1) DE3524991A1 (fr)
FR (1) FR2567540B1 (fr)
GB (1) GB2163750B (fr)
HU (1) HU194316B (fr)
IN (1) IN162268B (fr)
IT (1) IT1201429B (fr)
SU (1) SU1364343A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9394571B2 (en) 2007-04-27 2016-07-19 Pfenex Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196323A (en) * 1985-04-27 1993-03-23 Boehringer Ingelheim International Gmbh Process for preparing and purifying alpha-interferon
SU1703690A1 (ru) * 1986-04-30 1992-01-07 Всесоюзный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Рекомбинантна плазмидна ДНК @ 22, кодирующа синтез интерферона @ -11 человека, и штамм бактерии РSеUDомоNаS Sp. -продуцент- интерферона @ -11 человека
CN1553954A (zh) * 2001-03-30 2004-12-08 ������������ʳƷ�ۺ��о��� 通过赋予药物抗性突变提高次级代谢物产率的方法
US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
JP5602336B2 (ja) * 2004-01-16 2014-10-08 フェネックス インコーポレイテッド シュードモナス・フルオレッセンスにおける哺乳動物タンパク質の発現
JP2008507294A (ja) 2004-07-26 2008-03-13 ダウ グローバル テクノロジーズ インコーポレイティド 菌株遺伝子操作による改善されたタンパク質発現のための方法
SI2147105T1 (sl) 2007-05-02 2013-08-30 Merial Limited DNA-plazmidi z izboljšano ekspresijo in stabilnostjo
LT2220241T (lt) 2007-11-28 2016-12-12 The Trustees Of The University Of Pennsylvania Adenovirusas, apimantis beždžionių e adenoviruso sadv-39 kapsidės heksono baltymą, ir jo panaudojimas
EP2643465B1 (fr) 2010-11-23 2016-05-11 The Trustees Of The University Of Pennsylvania Adénovirus simiens de la sous-famille e a1321 et ses utilisations
BR112014028684A2 (pt) 2012-05-18 2017-07-25 Univ Pennsylvania subfamília e adenovírus de símio a1302, a1320, a1331 e a1337 e usos dos mesmos

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE870188A (fr) * 1977-09-08 1979-03-05 Ici Ltd Procede microbiologique
US4530901A (en) * 1980-01-08 1985-07-23 Biogen N.V. Recombinant DNA molecules and their use in producing human interferon-like polypeptides
DE3005897A1 (de) * 1980-02-16 1981-09-03 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enhtaltenden mikroorganismus
EP0042246B1 (fr) * 1980-06-12 1987-03-18 The Cancer Institute Of Japanese Foundation For Cancer Research Plasmid
CH651308A5 (de) * 1980-07-01 1985-09-13 Hoffmann La Roche Interferone und deren herstellung.
DE3280127D1 (de) * 1981-03-27 1990-04-12 Ici Plc Genetisch modifizierte mikroorganismen.
DE3122216A1 (de) * 1981-06-04 1982-12-23 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur herstellung eines mikroorganismus, welcher (alpha)-galactosidase, aber keine invertase bildet, so erhaltener mikroorganismus und seine verwendung
DK368882A (da) * 1981-08-25 1983-02-26 Alan John Kingsman Expessions vektorer
FR2516094A1 (fr) * 1981-11-06 1983-05-13 Wellcome Found Vecteur de clonage recombinant, micro-organisme transforme par ce vecteur, bacteriophage et procede pour produire un polypeptide heterologue
CA1210714A (fr) * 1982-03-23 1986-09-02 Alan Sloma .alpha.-INTERFERON GX-1
NZ207925A (en) * 1983-04-25 1988-05-30 Genentech Inc Yeast expression vehicle consisting of a yeast promoter and signal peptide encoding region linked to a heterologus peptide coding region; expression and culture

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9394571B2 (en) 2007-04-27 2016-07-19 Pfenex Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins

Also Published As

Publication number Publication date
JPS6156093A (ja) 1986-03-20
BG46981A1 (en) 1990-04-16
IN162268B (fr) 1988-04-23
GB2163750A (en) 1986-03-05
CH666051A5 (de) 1988-06-30
IT1201429B (it) 1989-02-02
DE3524991A1 (de) 1986-03-13
CA1264294A (fr) 1990-01-09
IT8521468A0 (it) 1985-07-08
HU194316B (en) 1988-01-28
US4680260A (en) 1987-07-14
FR2567540A1 (fr) 1986-01-17
HUT39476A (en) 1986-09-29
SU1364343A1 (ru) 1988-01-07
GB2163750B (en) 1987-09-16
GB8517795D0 (en) 1985-08-21

Similar Documents

Publication Publication Date Title
MA20739A1 (fr) Procede de preparation d'hydroxyalkylxanthines tertiaires
FR2621785B1 (fr) Procede de preparation d'un roux
FR2567540B1 (fr) Procede de preparation d'un interferon leucocytaire humain alpha-2
RO82759A (fr) Procede de preparation d'un glycoproteine a action antitumorale
FR2562541B1 (fr) Procede stereocontrole de preparation d'acetoxyazetidinone
FR2600793B1 (fr) Procede d'etude de microcalculateurs integres et microcalculateurs integres a structure modulaire obtenus par ce procede
FR2587366B1 (fr) Procede de preparation d'un lingot a partir de residus metalliques
FR2565590B1 (fr) Procede de preparation d'aminohydroxycephamcarboxylates
FR2630735B1 (fr) Procede de preparations d'halogenophenols
FR2633273B1 (fr) Procede de preparation de tetraflurorure d'uranium
PT88610A (pt) Procede de preparation de zircone stabilisee a l'yttrium
FR2638445B1 (fr) Nouveau procede de preparation d'un gel de phosphate de bismuth
IT8547759A0 (it) Procedimento per la produzione di un detergente e detergente cosi' ottenuto
FR2561645B1 (fr) Procede de preparation d'acides hydroxyalkylaminoacetiques
FR2577221B1 (fr) Procede de preparation d'une phenyluree substituee
FR2603886B1 (fr) Procede de preparation de carbonates d'alkenyle-1
FR2566663B1 (fr) Vermicide a base de mebendazole et procede pour la preparation de ce vermicide
FR2630741B1 (fr) Procede de preparation d'acryloyloxyethoxymethyl-melamines
FR2615185B1 (fr) Procede de preparation de trifluoromethyltoluene a partir d'halomethylbenzotrifluorure
FR2610924B1 (fr) Procede de preparation d'hydroxybiphenyles
FR2560199B1 (fr) Procede de preparation de l'i-brassicasterol
FR2567447B1 (fr) Procede de preparation d'un melange bitume-caoutchouc
FR2586420B1 (fr) Procede d'adherence
IT8467487A0 (it) Procedimento per la preparazionedi un prodotto ittico
IT8922020A0 (it) Unita' per la formazione di elementi a pastiglia

Legal Events

Date Code Title Description
ST Notification of lapse