FR2542741B1 - 3,4-diamino-1,2,5-thiadiazoles substitues possedant une activite antagoniste du recepteur-h2 de l'histamine - Google Patents

3,4-diamino-1,2,5-thiadiazoles substitues possedant une activite antagoniste du recepteur-h2 de l'histamine

Info

Publication number
FR2542741B1
FR2542741B1 FR838304934A FR8304934A FR2542741B1 FR 2542741 B1 FR2542741 B1 FR 2542741B1 FR 838304934 A FR838304934 A FR 838304934A FR 8304934 A FR8304934 A FR 8304934A FR 2542741 B1 FR2542741 B1 FR 2542741B1
Authority
FR
France
Prior art keywords
histamine
diamino
receptor antagonist
antagonist activity
thiadiazoles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR838304934A
Other languages
English (en)
Other versions
FR2542741A1 (fr
Inventor
Ronnie Ray Crenshaw
Aldo Antonio Algieri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FR2542741A1 publication Critical patent/FR2542741A1/fr
Application granted granted Critical
Publication of FR2542741B1 publication Critical patent/FR2542741B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
FR838304934A 1982-03-29 1983-03-25 3,4-diamino-1,2,5-thiadiazoles substitues possedant une activite antagoniste du recepteur-h2 de l'histamine Expired FR2542741B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36320782A 1982-03-29 1982-03-29

Publications (2)

Publication Number Publication Date
FR2542741A1 FR2542741A1 (fr) 1984-09-21
FR2542741B1 true FR2542741B1 (fr) 1989-12-08

Family

ID=23429274

Family Applications (2)

Application Number Title Priority Date Filing Date
FR838304934A Expired FR2542741B1 (fr) 1982-03-29 1983-03-25 3,4-diamino-1,2,5-thiadiazoles substitues possedant une activite antagoniste du recepteur-h2 de l'histamine
FR878707197A Expired FR2597867B1 (fr) 1982-03-29 1987-05-22 Ethanediimidamides substitues

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR878707197A Expired FR2597867B1 (fr) 1982-03-29 1987-05-22 Ethanediimidamides substitues

Country Status (30)

Country Link
JP (2) JPS58180477A (fr)
KR (1) KR880002209B1 (fr)
AT (1) AT386599B (fr)
AU (2) AU557577B2 (fr)
BE (1) BE896291A (fr)
CH (2) CH660880A5 (fr)
CS (2) CS250240B2 (fr)
DD (2) DD210909A5 (fr)
DE (1) DE3311281A1 (fr)
DK (2) DK166677B1 (fr)
ES (3) ES520982A0 (fr)
FR (2) FR2542741B1 (fr)
GB (2) GB2117769B (fr)
GR (1) GR78524B (fr)
HU (2) HU188742B (fr)
IE (1) IE55596B1 (fr)
IL (1) IL68259A0 (fr)
IT (1) IT1164633B (fr)
LU (1) LU84716A1 (fr)
MY (1) MY8700942A (fr)
NL (1) NL8301063A (fr)
NO (1) NO163055C (fr)
NZ (1) NZ203726A (fr)
OA (1) OA07356A (fr)
PT (1) PT76459B (fr)
SE (2) SE461040B (fr)
SU (2) SU1419518A3 (fr)
YU (1) YU44849B (fr)
ZA (1) ZA832154B (fr)
ZW (1) ZW7683A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2222083A (en) * 1982-12-14 1984-06-21 Smith Kline & French Laboratories Limited Pyridine derivatives
US4593039A (en) * 1984-04-02 1986-06-03 Merck & Co., Inc. 1-aryloxy-3-(substituted aminoalkylamino)-2-propanols
US4644006A (en) * 1984-06-22 1987-02-17 Bristol-Myers Company Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity
JPH0622828B2 (ja) * 1986-06-30 1994-03-30 フアナツク株式会社 直圧式型締機構
US20230349922A1 (en) 2020-08-11 2023-11-02 Université De Strasbourg H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3018289A (en) * 1960-02-10 1962-01-23 Wyandotte Chemicals Corp Process for preparing oxamidines
GB1595291A (en) * 1976-09-21 1981-08-12 Smith Kline French Lab Pyrimidone and thiopyrimidone derivatives
NL189197C (nl) * 1979-09-04 1993-02-01 Bristol Myers Squibb Co 3,4-digesubstitueerde-1,2,5-thiadiazool-1-oxiden en 1,1-dioxiden, bereiding daarvan alsmede farmaceutische preparaten.
EP0040696B1 (fr) * 1980-04-30 1986-08-27 Merck & Co. Inc. Aminothiadiazoles comme inhibiteurs de la sécrétion gastrique
AU2222083A (en) * 1982-12-14 1984-06-21 Smith Kline & French Laboratories Limited Pyridine derivatives

Also Published As

Publication number Publication date
AU586037B2 (en) 1989-06-29
ES8505978A1 (es) 1985-06-16
PT76459B (en) 1986-03-11
IL68259A0 (en) 1983-06-15
JPS58180477A (ja) 1983-10-21
OA07356A (fr) 1984-08-31
PT76459A (en) 1983-04-01
DD219768A5 (de) 1985-03-13
SE461040B (sv) 1989-12-18
YU74483A (en) 1986-02-28
CH660880A5 (de) 1987-05-29
FR2542741A1 (fr) 1984-09-21
DK141383D0 (da) 1983-03-28
ES8505977A1 (es) 1985-06-16
NL8301063A (nl) 1983-10-17
MY8700942A (en) 1987-12-31
SE8704689D0 (sv) 1987-11-25
SU1419518A3 (ru) 1988-08-23
IT8348005A0 (it) 1983-03-28
IE55596B1 (en) 1990-11-21
GB2149406A (en) 1985-06-12
HU188742B (en) 1986-05-28
CS250229B2 (en) 1987-04-16
ZA832154B (en) 1983-12-28
YU44849B (en) 1991-04-30
DD210909A5 (de) 1984-06-27
JPH06135925A (ja) 1994-05-17
BE896291A (fr) 1983-09-28
ES527686A0 (es) 1985-06-16
SE464302B (sv) 1991-04-08
CH655111A5 (de) 1986-03-27
SE8301725D0 (sv) 1983-03-28
AU557577B2 (en) 1986-12-24
ES527685A0 (es) 1985-06-16
FR2597867A1 (fr) 1987-10-30
SE8301725L (sv) 1983-11-25
AU6327286A (en) 1987-01-08
HU196386B (en) 1988-11-28
IT1164633B (it) 1987-04-15
GR78524B (fr) 1984-09-27
SU1355123A3 (ru) 1987-11-23
KR880002209B1 (ko) 1988-10-18
FR2597867B1 (fr) 1989-12-08
DE3311281A1 (de) 1983-11-24
GB2117769B (en) 1985-08-29
GB2149406B (en) 1986-01-02
NO163055B (no) 1989-12-18
NO831100L (no) 1983-09-30
DK81192D0 (da) 1992-06-18
DK166677B1 (da) 1993-06-28
DK141383A (da) 1983-09-30
GB8308518D0 (en) 1983-05-05
JPH0568472B2 (fr) 1993-09-29
GB2117769A (en) 1983-10-19
SE8704689L (sv) 1987-11-25
KR840004095A (ko) 1984-10-06
NO163055C (no) 1990-03-28
ES8404683A1 (es) 1984-05-16
LU84716A1 (fr) 1983-12-05
ES520982A0 (es) 1984-05-16
AT386599B (de) 1988-09-12
ATA111083A (de) 1988-02-15
ZW7683A1 (en) 1984-01-04
NZ203726A (en) 1986-05-09
IE830686L (en) 1983-09-29
GB8432809D0 (en) 1985-02-06
CS250240B2 (en) 1987-04-16
AU1290783A (en) 1983-10-06
DK81192A (da) 1992-06-18

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Legal Events

Date Code Title Description
ST Notification of lapse