FI820856L - 2-fenoxialkyl-1,2,4-triazol-3-on antidepressiver - Google Patents
2-fenoxialkyl-1,2,4-triazol-3-on antidepressiverInfo
- Publication number
- FI820856L FI820856L FI820856A FI820856A FI820856L FI 820856 L FI820856 L FI 820856L FI 820856 A FI820856 A FI 820856A FI 820856 A FI820856 A FI 820856A FI 820856 L FI820856 L FI 820856L
- Authority
- FI
- Finland
- Prior art keywords
- phenoxialkyl
- antidepressiver
- triazol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/067—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24446481 | 1981-03-16 | ||
US06/244,464 US4338317A (en) | 1981-03-16 | 1981-03-16 | Phenoxyethyl-1,2,4,-triazol-3-one antidepressants |
Publications (3)
Publication Number | Publication Date |
---|---|
FI820856L true FI820856L (fi) | 1982-09-17 |
FI73670B FI73670B (fi) | 1987-07-31 |
FI73670C FI73670C (fi) | 1987-11-09 |
Family
ID=22922879
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI820856A FI73670C (fi) | 1981-03-16 | 1982-03-12 | Foerfarande foer framstaellning av nya terapeutiskt anvaendbara fenoxialkyl-1,2,4-triazol-3-on derivat. |
Country Status (26)
Country | Link |
---|---|
US (1) | US4338317A (fi) |
JP (1) | JPS57159774A (fi) |
KR (1) | KR880001374B1 (fi) |
AT (1) | AT384022B (fi) |
BE (1) | BE892503A (fi) |
CA (1) | CA1198436A (fi) |
CH (1) | CH649539A5 (fi) |
CY (1) | CY1373A (fi) |
DE (1) | DE3209557A1 (fi) |
DK (1) | DK158728C (fi) |
ES (1) | ES8305756A1 (fi) |
FI (1) | FI73670C (fi) |
FR (1) | FR2501690B1 (fi) |
GB (1) | GB2096137B (fi) |
GR (1) | GR76076B (fi) |
HK (1) | HK4788A (fi) |
IE (1) | IE52788B1 (fi) |
IT (1) | IT1148137B (fi) |
KE (1) | KE3711A (fi) |
LU (1) | LU84011A1 (fi) |
MX (1) | MX9203176A (fi) |
NL (2) | NL190757C (fi) |
SE (1) | SE447256B (fi) |
SG (1) | SG30287G (fi) |
YU (1) | YU43256B (fi) |
ZA (1) | ZA821359B (fi) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4487773A (en) * | 1981-03-16 | 1984-12-11 | Mead Johnson & Company | 1,2,4-Triazol-3-one antidepressants |
US4386091A (en) * | 1982-02-24 | 1983-05-31 | Mead Johnson & Company | 2-Phenoxyalkyl-1,2,4-triazol-3-one antidepressants |
US4575555A (en) * | 1983-06-29 | 1986-03-11 | Mead Johnson & Company | 4-(3-Chlorophenyl)-1,2,3,6-tetrahydropyridine derivative |
AT388555B (de) * | 1983-06-29 | 1989-07-25 | Bristol Myers Co | Verfahren zur herstellung von neuen 1,2,4-triazol-3-on-derivaten |
US4613600A (en) * | 1983-09-30 | 1986-09-23 | Mead Johnson & Company | Antidepressant 1,2,4-triazolone compounds |
YU44721B (en) * | 1983-11-30 | 1990-12-31 | Bristol Myers Co | Process for obtaining 4-(2-phenoxyethyl)-1,2,4-triazolone |
CA1248531A (en) * | 1984-04-17 | 1989-01-10 | Jeffrey C. Watkins | 4-substituted piperazine-2-carboxylic acids |
US4784998A (en) * | 1987-04-06 | 1988-11-15 | Bristol-Myers Company | 1,3,4-oxadiazole pyschotropic compounds |
US5116852A (en) * | 1990-12-03 | 1992-05-26 | Bristol-Myers Squibb Co. | Treatment of sleep disorders |
US5266571A (en) * | 1992-01-09 | 1993-11-30 | Amer Moh Samir | Treatment of hemorrhoids with 5-HT2 antagonists |
US5256664A (en) * | 1992-04-28 | 1993-10-26 | Bristol-Myers Squibb Company | Antidepressant 3-halophenylpiperazinylpropyl derivatives of substituted triazolones and triazoldiones |
IT1256387B (it) * | 1992-11-13 | 1995-12-04 | Acraf | Procedimento per preparare triazoloni |
CA2160423A1 (en) * | 1994-11-02 | 1996-05-03 | Hemant N. Joshi | Salts of nefazodone having improved dissolution rates |
CA2187989A1 (en) | 1995-10-17 | 1997-04-18 | Ronald N. Marcus | Nefazodone: treatment of panic attack |
CA2182241C (en) * | 1996-07-29 | 2002-09-17 | Bo Lei | Methods for the manufacture of nefazodone |
WO1998004261A1 (en) * | 1996-07-31 | 1998-02-05 | Bristol-Myers Squibb Company | Nefazodone: use in migraine prophylaxis |
US5852020A (en) * | 1996-11-22 | 1998-12-22 | Bristol-Myers Squibb Company | Nefazodone: use in treating post traumatic stress disorder |
US5735873A (en) * | 1996-12-19 | 1998-04-07 | Maclean; David S. | Surgical tool handle |
US5917050A (en) * | 1998-02-11 | 1999-06-29 | Bayer Corporation | Process for preparing alkoxytriazolinones |
ES2152860B1 (es) | 1998-10-23 | 2001-08-16 | Finaf 92 Sa | Forma cristalina de la nefazodona y procedimiento para su preparacion. |
US6706282B1 (en) | 1998-11-02 | 2004-03-16 | Evangeline Cruz | Controlled delivery of phenoxyethyl-substituted 1,2,4-triazolones |
CA2369225A1 (en) | 1999-04-09 | 2000-10-19 | Sepracor Inc. | S-hydroxynefazodone |
ES2262515T3 (es) * | 1999-04-09 | 2006-12-01 | Sepracor Inc. | R-hidroxinefazodona. |
US6586437B2 (en) | 1999-04-09 | 2003-07-01 | Sepracor Inc. | (S)-hydroxynefazodone antipsychotic therapy |
US6469008B2 (en) | 1999-04-09 | 2002-10-22 | Sepracor Inc. | (R)-hydroxynefazodone antipsychotic therapy |
CA2356450C (en) | 2001-09-10 | 2003-11-25 | Brantford Chemicals Inc. | An improved process for the preparation of nefazodone hydrochloride |
DE50312523D1 (de) * | 2002-05-24 | 2010-04-29 | Carl-Fr Coester | Pharmazeutische wirkstoffkombination sowie deren verwendung |
GB0306604D0 (en) * | 2003-03-21 | 2003-04-30 | Curidium Ltd | Second medical use |
UA82875C2 (en) * | 2003-04-30 | 2008-05-26 | Insecticidal (dihalopropenyl) phenylalkyl substituted dihydrobenzofuran and dihydrobenzopyran derivatives and method for controlling insects | |
CA2547283C (en) * | 2003-11-26 | 2010-11-09 | Pfizer Products Inc. | Aminopyrazole derivatives as gsk-3 inhibitors |
WO2005102366A2 (en) * | 2004-04-19 | 2005-11-03 | Philip Maxwell Satow | Lithium combinations, and uses related thereto |
TW200612961A (en) * | 2004-05-18 | 2006-05-01 | Fmc Corp | Substituted cyclic urea derivatives |
SG163588A1 (en) | 2005-07-08 | 2010-08-30 | Braincells Inc | Methods for identifying agents and conditions that modulate neurogenesis |
CA2625153A1 (en) | 2005-10-21 | 2007-04-26 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
JP2009513672A (ja) | 2005-10-31 | 2009-04-02 | ブレインセルス,インコーポレイティド | 神経発生のgaba受容体媒介調節 |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
US7858611B2 (en) * | 2006-05-09 | 2010-12-28 | Braincells Inc. | Neurogenesis by modulating angiotensin |
EP2021000A2 (en) | 2006-05-09 | 2009-02-11 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
CA2651862A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
AU2007292848A1 (en) | 2006-09-08 | 2008-03-13 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
WO2008083204A2 (en) * | 2006-12-28 | 2008-07-10 | Braincells, Inc. | Modulation of neurogenesis by melatoninergic ligands |
US20080171750A1 (en) * | 2007-01-11 | 2008-07-17 | Braincells, Inc. | Modulation Of Neurogenesis With Use of Modafinil |
US8222254B2 (en) * | 2007-08-07 | 2012-07-17 | Prosarix Limited | 1, 2, 4-triazole derivatives as serotonergic modulators |
US9339500B2 (en) | 2008-03-04 | 2016-05-17 | Intra-Cellular Therapies, Inc. | Methods of treating vasomotor symptoms |
WO2009128058A1 (en) | 2008-04-18 | 2009-10-22 | UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN et al | Psycho-pharmaceuticals |
US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
TWI368512B (en) * | 2009-04-30 | 2012-07-21 | Univ Kaohsiung Medical | Pharmaceutical compositions comprising chlorophenyl piperazine derived compounds and use of the compounds in producing medicaments |
WO2012072665A1 (en) | 2010-11-30 | 2012-06-07 | Pharmaneuroboost N.V. | Compositions comprising pipamperone and serotonin antagonist reuptake inhibitors |
CN104402842A (zh) * | 2014-11-19 | 2015-03-11 | 苏州乔纳森新材料科技有限公司 | 一种哌嗪类药物中间体的合成方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1066857B (it) * | 1965-12-15 | 1985-03-12 | Acraf | Derivati della s ipiazolo 4.3 a piridina e processi per la loro preparazione |
IT1052119B (it) * | 1972-10-16 | 1981-06-20 | Sigma Tau Ind Farmaceuti | Derivati del triazolinone e procedimento per la loro preparazione |
-
1981
- 1981-03-16 US US06/244,464 patent/US4338317A/en not_active Expired - Lifetime
-
1982
- 1982-03-02 ZA ZA821359A patent/ZA821359B/xx unknown
- 1982-03-08 CA CA000397793A patent/CA1198436A/en not_active Expired
- 1982-03-09 GR GR67529A patent/GR76076B/el unknown
- 1982-03-11 YU YU525/82A patent/YU43256B/xx unknown
- 1982-03-11 NL NL8201021A patent/NL190757C/xx not_active IP Right Cessation
- 1982-03-12 IT IT47978/82A patent/IT1148137B/it active Protection Beyond IP Right Term
- 1982-03-12 FI FI820856A patent/FI73670C/fi not_active IP Right Cessation
- 1982-03-12 DK DK112582A patent/DK158728C/da not_active IP Right Cessation
- 1982-03-15 SE SE8201631A patent/SE447256B/sv not_active IP Right Cessation
- 1982-03-15 IE IE589/82A patent/IE52788B1/en active Protection Beyond IP Right Term
- 1982-03-15 LU LU84011A patent/LU84011A1/fr unknown
- 1982-03-15 GB GB8207539A patent/GB2096137B/en not_active Expired
- 1982-03-15 FR FR8204325A patent/FR2501690B1/fr not_active Expired
- 1982-03-15 CY CY137382A patent/CY1373A/xx unknown
- 1982-03-15 BE BE0/207574A patent/BE892503A/fr not_active IP Right Cessation
- 1982-03-15 CH CH1615/82A patent/CH649539A5/de not_active IP Right Cessation
- 1982-03-15 ES ES510449A patent/ES8305756A1/es not_active Expired
- 1982-03-16 AT AT0104582A patent/AT384022B/de not_active IP Right Cessation
- 1982-03-16 DE DE19823209557 patent/DE3209557A1/de active Granted
- 1982-03-16 JP JP57040315A patent/JPS57159774A/ja active Granted
- 1982-03-16 KR KR8201129A patent/KR880001374B1/ko active
-
1987
- 1987-03-27 SG SG302/87A patent/SG30287G/en unknown
- 1987-03-31 KE KE3711A patent/KE3711A/xx unknown
-
1988
- 1988-01-21 HK HK47/88A patent/HK4788A/xx not_active IP Right Cessation
-
1992
- 1992-06-23 MX MX9203176A patent/MX9203176A/es unknown
-
1997
- 1997-03-17 NL NL970014C patent/NL970014I2/nl unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TC | Name/ company changed in patent |
Owner name: BRISTOL-MYERS SQUIBB COMPANY |
|
SPCG | Supplementary protection certificate granted |
Spc suppl protection certif: L113 Extension date: 20070311 |
|
SPCL | Withdrawal, rejection or dismissal of a supplementary protection certificate |
Spc suppl protection certif: L113 |
|
MA | Patent expired |
Owner name: BRISTOL-MYERS SQUIBB COMPANY |