FR2457868B1 - - Google Patents

Info

Publication number
FR2457868B1
FR2457868B1 FR8011691A FR8011691A FR2457868B1 FR 2457868 B1 FR2457868 B1 FR 2457868B1 FR 8011691 A FR8011691 A FR 8011691A FR 8011691 A FR8011691 A FR 8011691A FR 2457868 B1 FR2457868 B1 FR 2457868B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8011691A
Other versions
FR2457868A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2457868A1 publication Critical patent/FR2457868A1/fr
Application granted granted Critical
Publication of FR2457868B1 publication Critical patent/FR2457868B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FR8011691A 1979-05-29 1980-05-27 Derives de l'imidazobenzodiazepine, leur preparation et leurs utilisations therapeutiques Granted FR2457868A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/043,417 US4226768A (en) 1979-05-29 1979-05-29 Process for the preparation of imidazobenzodiazepines

Publications (2)

Publication Number Publication Date
FR2457868A1 FR2457868A1 (fr) 1980-12-26
FR2457868B1 true FR2457868B1 (fr) 1985-04-05

Family

ID=21927076

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8011691A Granted FR2457868A1 (fr) 1979-05-29 1980-05-27 Derives de l'imidazobenzodiazepine, leur preparation et leurs utilisations therapeutiques

Country Status (7)

Country Link
US (1) US4226768A (fr)
JP (1) JPS55160778A (fr)
CH (1) CH644380A5 (fr)
DE (1) DE3020267A1 (fr)
FR (1) FR2457868A1 (fr)
GB (1) GB2052493B (fr)
IT (1) IT1131195B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4390471A (en) * 1978-05-15 1983-06-28 Hoffmann-La Roche Inc. Imidazodiazepines and processes therefor
JP2696342B2 (ja) * 1988-06-27 1998-01-14 日本曹達株式会社 アミジン誘導体、その製造方法及び殺ダニ剤・農園芸用殺菌剤
US5574028A (en) * 1994-10-31 1996-11-12 Eli Lilly And Company Method for treating anxiety
DE19824673A1 (de) * 1998-05-26 1999-12-02 Schering Ag Neue 2,3-Benzodiazepinderivate, deren Herstellung und Verwendung als Arzneimittel
EP4129297A1 (fr) 2016-03-18 2023-02-08 UWM Research Foundation, Inc. Traitement de troubles cognitifs et de symptômes de l'humeur dans des troubles neurodégénératifs et neuropsychiatriques avec des agonistes du récepteur gabaa contenant alpha5
JP7013446B2 (ja) * 2016-08-16 2022-02-15 ユーダブリューエム・リサーチ・ファウンデーション，インコーポレーテッド Ｇａｂａ（ａ）受容体モジュレーター、及び、喘息における気道過敏及び炎症を抑制するための方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA755418B (en) * 1974-09-11 1977-06-29 Hoffmann La Roche Diazepine derivatives
AT361486B (de) * 1975-08-07 1981-03-10 Hoffmann La Roche Verfahren zur herstellung von neuen imidazo(1,5 -a) (1,4)diazepinverbindungen, ihren salzen und optisch aktiven formen
US4125726A (en) * 1977-03-11 1978-11-14 Hoffmann-La Roche Inc. Imidazo[1,5-a][1,4]benzodiazepines

Also Published As

Publication number Publication date
CH644380A5 (de) 1984-07-31
US4226768A (en) 1980-10-07
FR2457868A1 (fr) 1980-12-26
DE3020267A1 (de) 1980-12-11
JPS55160778A (en) 1980-12-13
GB2052493A (en) 1981-01-28
GB2052493B (en) 1983-06-08
IT8022396A0 (it) 1980-05-29
IT1131195B (it) 1986-06-18
DE3020267C2 (fr) 1989-06-22

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Legal Events

Date Code Title Description
ST Notification of lapse