FR2449687A1 - Derives de phenothiazine et leur application en therapeutique - Google Patents

Derives de phenothiazine et leur application en therapeutique

Info

Publication number
FR2449687A1
FR2449687A1 FR8003661A FR8003661A FR2449687A1 FR 2449687 A1 FR2449687 A1 FR 2449687A1 FR 8003661 A FR8003661 A FR 8003661A FR 8003661 A FR8003661 A FR 8003661A FR 2449687 A1 FR2449687 A1 FR 2449687A1
Authority
FR
France
Prior art keywords
phenothiazine derivatives
therapeutic application
alcohyl
bopi
branched
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8003661A
Other languages
English (en)
Other versions
FR2449687B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of FR2449687A1 publication Critical patent/FR2449687A1/fr
Application granted granted Critical
Publication of FR2449687B1 publication Critical patent/FR2449687B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

L'INVENTION A POUR OBJET DE NOUVEAUX DERIVES DE PHENOTHIAZINE REPONDANT A LA FORMULE GENERALE: (CF DESSIN DANS BOPI) DANS LAQUELLE R REPRESENTE UN GROUPE ALCOYLE OU ALCENYLE LINEAIRE OU RAMIFIE EN C5 A C15, ET LEURS SELS D'ADDITION AVEC DES ACIDES. CES COMPOSES ONT NOTAMMENT UNE ACTIVITE ANTIPSYCHOTIQUE.
FR8003661A 1979-02-22 1980-02-20 Derives de phenothiazine et leur application en therapeutique Granted FR2449687A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1905279A JPS55111483A (en) 1979-02-22 1979-02-22 Novel phenothiazine derivative and psychotropic drug comprising it

Publications (2)

Publication Number Publication Date
FR2449687A1 true FR2449687A1 (fr) 1980-09-19
FR2449687B1 FR2449687B1 (fr) 1983-05-13

Family

ID=11988648

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8003661A Granted FR2449687A1 (fr) 1979-02-22 1980-02-20 Derives de phenothiazine et leur application en therapeutique

Country Status (10)

Country Link
US (1) US4514395A (fr)
JP (1) JPS55111483A (fr)
BE (1) BE881849A (fr)
DE (1) DE3006712A1 (fr)
ES (1) ES8103079A1 (fr)
FR (1) FR2449687A1 (fr)
GB (1) GB2073171B (fr)
IT (1) IT1150006B (fr)
NL (1) NL8001005A (fr)
SE (1) SE447111B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8413915D0 (en) * 1984-05-31 1984-07-04 Wellcome Found Phenothiazine compounds
FR2720940A1 (fr) * 1994-06-13 1995-12-15 Rhone Poulenc Rorer Sa Application du (+)-N-propyl [(pyrrolidinyl-1)-1 propyl-2]-10 phénothiazinecarboxamide comme antidépresseur.
WO2019195789A1 (fr) * 2018-04-06 2019-10-10 Camp4 Therapeutics Corporation Dérivés de phénothiazine et leurs utilisations

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE572181A (fr) * 1957-10-21 1959-04-18
FR475M (fr) * 1959-05-05 1967-05-02

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB834370A (en) * 1957-02-21 1960-05-04 Abbott Lab Phenothiazine derivatives
US3193549A (en) * 1958-07-07 1965-07-06 Sterling Drug Inc 10-[(1-piperidyl)lower-alkyl]-trifluoromethylphenothiazines
CH379507A (de) * 1962-02-01 1964-07-15 Cilag Chemie Aktiengesellschaf Verfahren zur Herstellung von neuen 10-(1'-Hydroxyalkyl-pyrrolidyl-(3')-methyl)-phenothiazinen
US3320243A (en) * 1964-03-10 1967-05-16 Cilag Chemie New hydroxy compounds and their esters and ethers
US4018922A (en) * 1971-05-14 1977-04-19 Roussel-Uclaf 10-(Piperidin o-alkyl)-phenothiazines
GB1460713A (en) * 1973-06-08 1977-01-06 Kefalas As 7-fluoro substituted phenothiazines method for preparation thereof and compositions bladed rotor for a gas turbine engine
AR207789A1 (es) * 1974-01-22 1976-10-29 Rhone Poulenc Ind Procedimiento para preparar nuevos esteres derivados de 2-hidroxi-2-dimetilsulfamoil-6-(((hidroxi-2-etil)-4-pipedidino)-3-propil)-10-fenotiazina
GB1517385A (en) * 1975-08-29 1978-07-12 Eisai Co Ltd Phenothiazine derivatives

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE572181A (fr) * 1957-10-21 1959-04-18
FR475M (fr) * 1959-05-05 1967-05-02

Also Published As

Publication number Publication date
NL8001005A (nl) 1980-08-26
BE881849A (fr) 1980-06-16
ES488808A0 (es) 1981-02-16
IT8020038A1 (it) 1981-08-20
US4514395A (en) 1985-04-30
GB2073171A (en) 1981-10-14
SE8001361L (sv) 1980-08-23
IT1150006B (it) 1986-12-10
IT8020038A0 (it) 1980-02-20
SE447111B (sv) 1986-10-27
ES8103079A1 (es) 1981-02-16
FR2449687B1 (fr) 1983-05-13
JPS55111483A (en) 1980-08-28
DE3006712A1 (de) 1980-09-04
GB2073171B (en) 1983-03-16

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Legal Events

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