FR2426088A1 - - Google Patents
Info
- Publication number
- FR2426088A1 FR2426088A1 FR7912621A FR7912621A FR2426088A1 FR 2426088 A1 FR2426088 A1 FR 2426088A1 FR 7912621 A FR7912621 A FR 7912621A FR 7912621 A FR7912621 A FR 7912621A FR 2426088 A1 FR2426088 A1 FR 2426088A1
- Authority
- FR
- France
- Prior art keywords
- beta
- lactamase inhibitor
- sodium salt
- micromonospora
- inhibitor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/99—Enzyme inactivation by chemical treatment
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/04—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/29—Micromonospora
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/867—Micromonospora
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/867—Micromonospora
- Y10S435/868—Micromonospora chalcea
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Abstract
Pour obtenir un nouvel inhibiteur de la beta -lactamase appelé EM 4615, on cultive une espèce de Micromonospora (en particulier une nouvelle souche constituée de Micromonospora chalcea ATCC n degrés 31395) dans des conditions de fermentation aérobies et on isole l'inhibiteur du milieu de fermentation par extraction; l'inhibiteur de la beta -lactamase et ses sels, en particulier le sel de sodium et le sel de baryum, présentent des propriétés physiques caractéristiques (voir spectre infrarouge du sel de sodium). L'invention s'applique en particulier à un inhibiteur de la beta -lactamase utile pour accroître l'efficacité des antibiotiques de type beta -lactame tels que les pénicillines et les céphalosporines.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/906,906 US4205068A (en) | 1978-05-18 | 1978-05-18 | β-Lactamase inhibitor EM4615 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2426088A1 true FR2426088A1 (fr) | 1979-12-14 |
FR2426088B1 FR2426088B1 (fr) | 1983-07-08 |
Family
ID=25423189
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7912621A Expired FR2426088B1 (fr) | 1978-05-18 | 1979-05-17 |
Country Status (6)
Country | Link |
---|---|
US (1) | US4205068A (fr) |
JP (1) | JPS54163897A (fr) |
DE (1) | DE2920293A1 (fr) |
FR (1) | FR2426088B1 (fr) |
GB (1) | GB2021096A (fr) |
IT (1) | IT7949074A0 (fr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0416814B1 (fr) * | 1989-09-04 | 2002-04-24 | Pfizer Inc. | Dérivés de céphalosporine antibactériens |
KR100192862B1 (ko) * | 1991-01-10 | 1999-06-15 | 슈테펜엘.네스비트 | 항당뇨병제로서 유용한 신규한 글루코하이드롤라제 억제제 |
EP2138366B1 (fr) * | 2008-06-26 | 2013-03-20 | Kawasaki Jukogyo Kabushiki Kaisha | Système de contrôle de glissement pour véhicule |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH435560A (de) * | 1962-04-02 | 1967-05-15 | Scherico Ltd | Verfahren zur Herstellung neuer Antibiotica |
FR2106582A1 (fr) * | 1970-09-17 | 1972-05-05 | Beecham Group Ltd | |
JPS49116297A (fr) * | 1973-03-12 | 1974-11-06 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4078056A (en) * | 1974-10-18 | 1978-03-07 | Schering Corporation | Antibiotic complex from micromonospora arborensis |
-
1978
- 1978-05-18 US US05/906,906 patent/US4205068A/en not_active Expired - Lifetime
-
1979
- 1979-05-02 GB GB7915269A patent/GB2021096A/en not_active Withdrawn
- 1979-05-17 FR FR7912621A patent/FR2426088B1/fr not_active Expired
- 1979-05-17 IT IT7949074A patent/IT7949074A0/it unknown
- 1979-05-18 JP JP6212279A patent/JPS54163897A/ja active Pending
- 1979-05-18 DE DE19792920293 patent/DE2920293A1/de not_active Withdrawn
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH435560A (de) * | 1962-04-02 | 1967-05-15 | Scherico Ltd | Verfahren zur Herstellung neuer Antibiotica |
FR2106582A1 (fr) * | 1970-09-17 | 1972-05-05 | Beecham Group Ltd | |
GB1363075A (en) * | 1970-09-17 | 1974-08-14 | Beecham Group Ltd | Enzyme inhibitor |
JPS49116297A (fr) * | 1973-03-12 | 1974-11-06 |
Non-Patent Citations (2)
Title |
---|
CA1975 * |
EXBK/76 * |
Also Published As
Publication number | Publication date |
---|---|
US4205068A (en) | 1980-05-27 |
IT7949074A0 (it) | 1979-05-17 |
JPS54163897A (en) | 1979-12-26 |
FR2426088B1 (fr) | 1983-07-08 |
DE2920293A1 (de) | 1979-11-22 |
GB2021096A (en) | 1979-11-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |