FR2406639A1 - Antibiotiques de desoxynarasine et leurs utilisations therapeutiques - Google Patents
Antibiotiques de desoxynarasine et leurs utilisations therapeutiquesInfo
- Publication number
- FR2406639A1 FR2406639A1 FR7829423A FR7829423A FR2406639A1 FR 2406639 A1 FR2406639 A1 FR 2406639A1 FR 7829423 A FR7829423 A FR 7829423A FR 7829423 A FR7829423 A FR 7829423A FR 2406639 A1 FR2406639 A1 FR 2406639A1
- Authority
- FR
- France
- Prior art keywords
- deoxynarasin
- therapeutic uses
- desoxynarasin
- antibiotics
- narasin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
- C12R2001/485—Streptomyces aureofaciens
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
- Y10S435/889—Streptomyces aureofaciens
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Feed For Specific Animals (AREA)
- Fodder In General (AREA)
Abstract
L'invention concerne le complexe antibiotique de désoxynarasine, comprenant la 20-désoxynarasine et la 20-désoxy-épi-17-narasine. On obtient le complexe antibiotique par fermentation aérobie en immersion de Streptomyces aureofaciens NRRL 11181 ou d'un Streptomyces aureofaciens ayant les mêmes possibilités biosynthétiques que NRRL 11181. On sépare et on isole la 20-désoxynarasine et la 20-désoxy-épi-17-narasine par chromatographie. Le complexe et ses constituants séparés ont différentes utilités thérapeutiques et sont particulièrement utiles comme agents antibactériens et anticoccidiens et comme agents améliorant l'efficacité de l'utilisation des aliments chez les ruminants.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/844,087 US4141907A (en) | 1977-10-20 | 1977-10-20 | Deoxynarasin antibiotics |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2406639A1 true FR2406639A1 (fr) | 1979-05-18 |
FR2406639B1 FR2406639B1 (fr) | 1981-08-14 |
Family
ID=25291778
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7829423A Granted FR2406639A1 (fr) | 1977-10-20 | 1978-10-16 | Antibiotiques de desoxynarasine et leurs utilisations therapeutiques |
Country Status (33)
Country | Link |
---|---|
US (1) | US4141907A (fr) |
EP (1) | EP0001709B1 (fr) |
JP (1) | JPS5470276A (fr) |
AR (1) | AR217869A1 (fr) |
AT (1) | AT362499B (fr) |
AU (1) | AU519966B2 (fr) |
BE (1) | BE871274A (fr) |
CA (1) | CA1119541A (fr) |
CH (1) | CH636903A5 (fr) |
CS (1) | CS204037B2 (fr) |
DD (1) | DD139520A5 (fr) |
DE (1) | DE2861882D1 (fr) |
DK (1) | DK465978A (fr) |
ES (1) | ES474327A1 (fr) |
FI (1) | FI58791C (fr) |
FR (1) | FR2406639A1 (fr) |
GB (1) | GB2006774B (fr) |
GR (1) | GR71734B (fr) |
HU (1) | HU179463B (fr) |
IE (1) | IE47665B1 (fr) |
IL (1) | IL55738A (fr) |
IT (1) | IT1101615B (fr) |
MX (1) | MX5603E (fr) |
MY (1) | MY8500595A (fr) |
NO (1) | NO783545L (fr) |
NZ (1) | NZ188670A (fr) |
PH (1) | PH14339A (fr) |
PL (1) | PL117570B1 (fr) |
PT (1) | PT68661A (fr) |
RO (1) | RO77417A (fr) |
SU (1) | SU818492A3 (fr) |
YU (1) | YU241578A (fr) |
ZA (1) | ZA785804B (fr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2024806B (en) * | 1978-03-16 | 1982-05-06 | Taisho Pharmaceutical Co Ltd | Onomycin derivatives |
IE49936B1 (en) * | 1979-07-11 | 1986-01-08 | Int Minerals & Chem Corp | Zinc-containing antibiotic agents |
US4309504A (en) * | 1980-01-28 | 1982-01-05 | Eli Lilly And Company | Process for preparing narasin |
US4394377A (en) * | 1981-07-31 | 1983-07-19 | Syntex (U.S.A.) Inc. | Ruminant animal performance by co-administering choline and propionate enchancers |
US4625041A (en) * | 1984-02-17 | 1986-11-25 | Pfizer Inc. | Acidic polycyclic ether antibiotic |
US4613503A (en) * | 1984-10-11 | 1986-09-23 | The Dow Chemical Company | Antibiotic A26201-1 and antibiotic A26201-2 produced by a novel strain of actinoplanes |
US4859599A (en) * | 1984-10-11 | 1989-08-22 | The Dow Chemical Company | Antibiotic A26201-1 and antibiotic A26201-2 produced by a novel strain of actinoplanes |
US5041374A (en) * | 1986-05-29 | 1991-08-20 | International Minerals & Chemical Corp. | Polyether antibiotic recovery and purification |
US5049495A (en) * | 1986-05-29 | 1991-09-17 | International Minerals & Chemical Corp. | Fermentation method for producing polyether antibiotics |
US5047338A (en) * | 1986-05-29 | 1991-09-10 | International Minerals & Chemical Corp. | Polyester Antibiotic preparation |
US20080161324A1 (en) * | 2006-09-14 | 2008-07-03 | Johansen Lisa M | Compositions and methods for treatment of viral diseases |
CN108743905A (zh) * | 2018-08-24 | 2018-11-06 | 河南科技大学第附属医院 | 一种治疗感冒的中药配方及其制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3753887A (en) | 1969-06-04 | 1973-08-21 | Hydronautics | Alkali metal specific measuring electrode |
US3947586A (en) | 1974-05-20 | 1976-03-30 | Hoffmann-La Roche Inc. | Method of combatting swine dysentery |
US4038384A (en) * | 1974-06-10 | 1977-07-26 | Eli Lilly And Company | Antibiotic a-28086 and process for production thereof |
US3985893A (en) | 1974-10-29 | 1976-10-12 | Eli Lilly And Company | Method for treating cardiac insufficiency with antibiotic A-23187 |
US4035481A (en) | 1975-04-21 | 1977-07-12 | Eli Lilly And Company | Antibiotic A-28086 and process for production thereof |
US4009262A (en) | 1975-04-21 | 1977-02-22 | Eli Lilly And Company | Antibiotic a-28086 recovery process |
-
1977
- 1977-10-20 US US05/844,087 patent/US4141907A/en not_active Expired - Lifetime
-
1978
- 1978-10-15 IL IL55738A patent/IL55738A/xx unknown
- 1978-10-16 BE BE1009097A patent/BE871274A/fr not_active IP Right Cessation
- 1978-10-16 ZA ZA785804A patent/ZA785804B/xx unknown
- 1978-10-16 RO RO7895412A patent/RO77417A/fr unknown
- 1978-10-16 AR AR274094A patent/AR217869A1/es active
- 1978-10-16 FR FR7829423A patent/FR2406639A1/fr active Granted
- 1978-10-16 YU YU02415/78A patent/YU241578A/xx unknown
- 1978-10-16 PH PH21709A patent/PH14339A/en unknown
- 1978-10-16 NZ NZ188670A patent/NZ188670A/xx unknown
- 1978-10-16 PT PT68661A patent/PT68661A/pt unknown
- 1978-10-17 GB GB7840888A patent/GB2006774B/en not_active Expired
- 1978-10-17 DE DE7878300514T patent/DE2861882D1/de not_active Expired
- 1978-10-17 EP EP78300514A patent/EP0001709B1/fr not_active Expired
- 1978-10-17 CA CA000313589A patent/CA1119541A/fr not_active Expired
- 1978-10-17 AU AU40776/78A patent/AU519966B2/en not_active Expired
- 1978-10-18 GR GR57458A patent/GR71734B/el unknown
- 1978-10-18 FI FI783174A patent/FI58791C/fi not_active IP Right Cessation
- 1978-10-18 CS CS786777A patent/CS204037B2/cs unknown
- 1978-10-18 ES ES474327A patent/ES474327A1/es not_active Expired
- 1978-10-19 NO NO783545A patent/NO783545L/no unknown
- 1978-10-19 HU HU78EI817A patent/HU179463B/hu unknown
- 1978-10-19 JP JP12940478A patent/JPS5470276A/ja active Granted
- 1978-10-19 DK DK465978A patent/DK465978A/da unknown
- 1978-10-19 CH CH1083778A patent/CH636903A5/fr not_active IP Right Cessation
- 1978-10-19 IE IE2078/78A patent/IE47665B1/en not_active IP Right Cessation
- 1978-10-19 SU SU782676001A patent/SU818492A3/ru active
- 1978-10-19 IT IT28926/78A patent/IT1101615B/it active
- 1978-10-19 AT AT750778A patent/AT362499B/de not_active IP Right Cessation
- 1978-10-19 MX MX787479U patent/MX5603E/es unknown
- 1978-10-20 DD DD78208586A patent/DD139520A5/de unknown
- 1978-10-20 PL PL1978210410A patent/PL117570B1/pl unknown
-
1985
- 1985-12-30 MY MY595/85A patent/MY8500595A/xx unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse | ||
ST | Notification of lapse |