FR2373517A1 - Pseudopeptides comportant le radical d'une molecule therapeutiquement active, utiles comme medicaments - Google Patents
Pseudopeptides comportant le radical d'une molecule therapeutiquement active, utiles comme medicamentsInfo
- Publication number
- FR2373517A1 FR2373517A1 FR7736995A FR7736995A FR2373517A1 FR 2373517 A1 FR2373517 A1 FR 2373517A1 FR 7736995 A FR7736995 A FR 7736995A FR 7736995 A FR7736995 A FR 7736995A FR 2373517 A1 FR2373517 A1 FR 2373517A1
- Authority
- FR
- France
- Prior art keywords
- radical
- useful
- active molecule
- therapically
- medicinal products
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
La présente invention concerne des pseudopeptides. Pseudopeptide constitué par au moins un radical peptidique relié par une liaison peptide à au moins un radical correspondant à une molécule ou un dérivé d'une molécule thérapeutiquement active telle que l'amphétamine ou la dopamine ainsi que les sels, esters et amides correspondants Ces produits sont utiles comme médicaments.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB51632/76A GB1592552A (en) | 1976-12-10 | 1976-12-10 | Pseudopeptides used as medicaments |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2373517A1 true FR2373517A1 (fr) | 1978-07-07 |
FR2373517B1 FR2373517B1 (fr) | 1981-11-27 |
Family
ID=10460796
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7736995A Granted FR2373517A1 (fr) | 1976-12-10 | 1977-12-08 | Pseudopeptides comportant le radical d'une molecule therapeutiquement active, utiles comme medicaments |
Country Status (5)
Country | Link |
---|---|
US (1) | US4297346A (fr) |
CH (1) | CH628324A5 (fr) |
DE (1) | DE2755036A1 (fr) |
FR (1) | FR2373517A1 (fr) |
GB (1) | GB1592552A (fr) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2489320A1 (fr) * | 1980-05-06 | 1982-03-05 | Schally Andrew | Nouveaux peptides anorexigenes |
EP0099057A2 (fr) * | 1982-07-14 | 1984-01-25 | BASF Aktiengesellschaft | Dérivés N-acylés de peptides, leur préparation et utilisation dans la lutte contre les maladies et moyen de lutte |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4880781A (en) * | 1984-08-06 | 1989-11-14 | The Upjohn Company | Renin inhibitory peptides containing an N-alkyl-histidine moiety |
US5834433A (en) * | 1990-07-26 | 1998-11-10 | Merrell Pharmaceuticals Inc. | Compounds and pharmaceutical uses of peptides of bombesin and GRP |
JP3350701B2 (ja) * | 1991-05-23 | 2002-11-25 | メレルダウファーマスーティカルズ インコーポレイテッド | ボンベシン類似体類 |
US5939412A (en) * | 1992-06-26 | 1999-08-17 | Smithkline Beecham Corporation | Bicyclic fibrinogen antagonists |
ATE228115T1 (de) * | 1991-06-28 | 2002-12-15 | Smithkline Beecham Corp | Bizyklische fibrinogenantagonisten |
CA2129032A1 (fr) * | 1992-02-07 | 1993-08-19 | Judson V. Edwards | Analogues de la bombesine possedant des derives modifies de la phenylanine |
MA23420A1 (fr) * | 1994-01-07 | 1995-10-01 | Smithkline Beecham Corp | Antagonistes bicycliques de fibrinogene. |
US6458784B1 (en) | 1994-06-29 | 2002-10-01 | Smithkline Beecham Corporation | Vitronectin receptor antagonists |
US5977101A (en) * | 1995-06-29 | 1999-11-02 | Smithkline Beecham Corporation | Benzimidazoles/Imidazoles Linked to a Fibrinogen Receptor Antagonist Template Having Vitronectin Receptor Antagonist Activity |
RU2141483C1 (ru) * | 1997-07-04 | 1999-11-20 | Небольсин Владимир Евгеньевич | Производные пептидов или их фармацевтически приемлемые соли, способ их получения, применение и фармацевтическая композиция |
US6737408B1 (en) * | 1997-08-07 | 2004-05-18 | University Of Cincinnati | Compounds for control of appetite, blood pressure, cardiovascular response, libido, and circadian rhythm |
US6716452B1 (en) * | 2000-08-22 | 2004-04-06 | New River Pharmaceuticals Inc. | Active agent delivery systems and methods for protecting and administering active agents |
US7060708B2 (en) * | 1999-03-10 | 2006-06-13 | New River Pharmaceuticals Inc. | Active agent delivery systems and methods for protecting and administering active agents |
US7163918B2 (en) | 2000-08-22 | 2007-01-16 | New River Pharmaceuticals Inc. | Iodothyronine compositions |
US8394813B2 (en) * | 2000-11-14 | 2013-03-12 | Shire Llc | Active agent delivery systems and methods for protecting and administering active agents |
GB0107924D0 (en) * | 2001-03-29 | 2001-05-23 | Angeletti P Ist Richerche Bio | Inhibitor of hepatitis C virus NS3 protease |
WO2003072046A2 (fr) * | 2002-02-22 | 2003-09-04 | New River Pharmaceuticals Inc. | Nouveaux composes pharmaceutiques a liberation prolongee destines a empecher la consommation abusive de substances controlees |
US7169752B2 (en) | 2003-09-30 | 2007-01-30 | New River Pharmaceuticals Inc. | Compounds and compositions for prevention of overdose of oxycodone |
US20060014697A1 (en) | 2001-08-22 | 2006-01-19 | Travis Mickle | Pharmaceutical compositions for prevention of overdose or abuse |
WO2003018538A1 (fr) | 2001-08-31 | 2003-03-06 | Ajinomoto Co., Inc. | Nouveaux derives de diarylalcene et nouveaux derives de diarylalcane |
US7105486B2 (en) * | 2002-02-22 | 2006-09-12 | New River Pharmaceuticals Inc. | Abuse-resistant amphetamine compounds |
US7700561B2 (en) * | 2002-02-22 | 2010-04-20 | Shire Llc | Abuse-resistant amphetamine prodrugs |
US7659253B2 (en) * | 2002-02-22 | 2010-02-09 | Shire Llc | Abuse-resistant amphetamine prodrugs |
NZ544162A (en) * | 2003-05-29 | 2008-09-26 | Shire Llc | Abuse resistant amphetamine compounds |
JP4390568B2 (ja) * | 2004-01-19 | 2009-12-24 | 富士通株式会社 | 遅延測定システム |
US20070197445A1 (en) * | 2006-01-18 | 2007-08-23 | University Of Cincinnati | Compounds for control of appetite |
DK2560486T3 (en) | 2010-04-21 | 2019-02-04 | Signature Therapeutics Inc | COMPOSITIONS COMPREHENSIVE ENZYM-TENDABLE AMPHETAMINE PRODRUGS AND ITS INHIBITORS |
EP4198029A1 (fr) * | 2015-08-17 | 2023-06-21 | University Health Network | Inhibiteurs d'enzymes peptidyl arginine désiminases (pad) et leurs utilisations |
WO2019076675A1 (fr) * | 2017-10-06 | 2019-04-25 | Instituto De Medicina Molecular | Traitement d'états liés à l'obésité |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3878187A (en) * | 1972-09-11 | 1975-04-15 | Syva Co | Polypeptide derivatives of amphetamine and analogs for immunoassays |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR4550M (fr) * | 1964-09-15 | 1966-11-02 | ||
US3843447A (en) * | 1972-09-22 | 1974-10-22 | Syva Co | Photolytically activated coupling to polypeptides |
US3998799A (en) * | 1973-11-02 | 1976-12-21 | Interx Research Corporation | Novel, transient pro-drug forms of l-dopa |
US4064235A (en) * | 1975-08-21 | 1977-12-20 | Eisai Co., Ltd. | Dopamine derivative compounds, preparation thereof and medicine containing same |
US4043989A (en) * | 1975-09-11 | 1977-08-23 | Syva Company | Oxazepam derivatives for immunoassay reagents |
US4064236A (en) * | 1975-12-23 | 1977-12-20 | Merck & Co., Inc. | Peptide carbazates and pharmaceutical composition |
-
1976
- 1976-12-10 GB GB51632/76A patent/GB1592552A/en not_active Expired
-
1977
- 1977-12-08 FR FR7736995A patent/FR2373517A1/fr active Granted
- 1977-12-09 DE DE19772755036 patent/DE2755036A1/de not_active Withdrawn
- 1977-12-09 CH CH1515777A patent/CH628324A5/fr not_active IP Right Cessation
-
1979
- 1979-12-07 US US06/101,555 patent/US4297346A/en not_active Expired - Lifetime
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3878187A (en) * | 1972-09-11 | 1975-04-15 | Syva Co | Polypeptide derivatives of amphetamine and analogs for immunoassays |
Non-Patent Citations (2)
Title |
---|
CA1968 * |
CA1974 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2489320A1 (fr) * | 1980-05-06 | 1982-03-05 | Schally Andrew | Nouveaux peptides anorexigenes |
EP0099057A2 (fr) * | 1982-07-14 | 1984-01-25 | BASF Aktiengesellschaft | Dérivés N-acylés de peptides, leur préparation et utilisation dans la lutte contre les maladies et moyen de lutte |
EP0099057A3 (en) * | 1982-07-14 | 1984-09-12 | Basf Aktiengesellschaft | N-acyl derivatives of peptides, their manufacture and use in combating diseases and means therefor |
Also Published As
Publication number | Publication date |
---|---|
GB1592552A (en) | 1981-07-08 |
CH628324A5 (fr) | 1982-02-26 |
FR2373517B1 (fr) | 1981-11-27 |
DE2755036A1 (de) | 1978-06-15 |
US4297346A (en) | 1981-10-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |