FR2364928A1 - Procede de preparation de steroides halogenes en position 9,11, et les composes obtenus par le procede - Google Patents
Procede de preparation de steroides halogenes en position 9,11, et les composes obtenus par le procedeInfo
- Publication number
- FR2364928A1 FR2364928A1 FR7727739A FR7727739A FR2364928A1 FR 2364928 A1 FR2364928 A1 FR 2364928A1 FR 7727739 A FR7727739 A FR 7727739A FR 7727739 A FR7727739 A FR 7727739A FR 2364928 A1 FR2364928 A1 FR 2364928A1
- Authority
- FR
- France
- Prior art keywords
- preparation
- compounds obtained
- halogen steroids
- steroids
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
- C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
- C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procédé de préparation de stéroïdes halogénés en positions 9, 11, et les composés obtenus par le procédé. Ce procédé de l'invention se caractérise par le fait qu'il consiste à faire réagir un 9 alpha-chloro-11-bêta-hydroxy-stéroide avec un composé de formule F3 SX, dans laquelle X représente le groupe amino provenant d'une amine secondaire. Application à l'industrie pharmaceutique.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
LU75809A LU75809A1 (fr) | 1976-09-16 | 1976-09-16 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2364928A1 true FR2364928A1 (fr) | 1978-04-14 |
FR2364928B1 FR2364928B1 (fr) | 1981-03-06 |
Family
ID=19728351
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7727739A Granted FR2364928A1 (fr) | 1976-09-16 | 1977-09-14 | Procede de preparation de steroides halogenes en position 9,11, et les composes obtenus par le procede |
Country Status (13)
Country | Link |
---|---|
JP (1) | JPS5337652A (fr) |
AT (1) | AT356303B (fr) |
AU (1) | AU514425B2 (fr) |
BE (1) | BE858709A (fr) |
CA (1) | CA1105003A (fr) |
DE (1) | DE2741067A1 (fr) |
DK (1) | DK410077A (fr) |
FR (1) | FR2364928A1 (fr) |
GB (1) | GB1584826A (fr) |
LU (1) | LU75809A1 (fr) |
NL (1) | NL7710086A (fr) |
SE (1) | SE7710337L (fr) |
ZA (1) | ZA775537B (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0029151A2 (fr) * | 1979-11-16 | 1981-05-27 | STEROSYNT Ltd. | 6-Alpha-fluoro-9-alpha-chloro-prednisolone-17,21-diesters, compositions pharmaceutiques les contenant et intermédiaires |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1209140B (it) * | 1979-11-16 | 1989-07-10 | Prochem Ets | 6 alfa-fluoro-prednisolone 17,21-diesteri. |
-
1976
- 1976-09-16 LU LU75809A patent/LU75809A1/xx unknown
-
1977
- 1977-09-13 DE DE19772741067 patent/DE2741067A1/de not_active Withdrawn
- 1977-09-14 CA CA286,727A patent/CA1105003A/fr not_active Expired
- 1977-09-14 FR FR7727739A patent/FR2364928A1/fr active Granted
- 1977-09-14 GB GB38343/77A patent/GB1584826A/en not_active Expired
- 1977-09-14 NL NL7710086A patent/NL7710086A/xx not_active Application Discontinuation
- 1977-09-15 ZA ZA00775537A patent/ZA775537B/xx unknown
- 1977-09-15 BE BE180914A patent/BE858709A/fr unknown
- 1977-09-15 SE SE7710337A patent/SE7710337L/ not_active Application Discontinuation
- 1977-09-15 AU AU28848/77A patent/AU514425B2/en not_active Expired
- 1977-09-15 DK DK410077A patent/DK410077A/da unknown
- 1977-09-15 AT AT663077A patent/AT356303B/de not_active IP Right Cessation
- 1977-09-16 JP JP11060977A patent/JPS5337652A/ja active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0029151A2 (fr) * | 1979-11-16 | 1981-05-27 | STEROSYNT Ltd. | 6-Alpha-fluoro-9-alpha-chloro-prednisolone-17,21-diesters, compositions pharmaceutiques les contenant et intermédiaires |
EP0029151A3 (en) * | 1979-11-16 | 1981-08-26 | Sterosynt Ltd. | 6-alpha-fluoro-9-alpha-chloro-prednisolone-17,21 diesters, pharmaceutical compositions containing them and intermediates |
Also Published As
Publication number | Publication date |
---|---|
CA1105003A (fr) | 1981-07-14 |
ZA775537B (en) | 1978-07-26 |
DK410077A (da) | 1978-03-17 |
ATA663077A (de) | 1979-09-15 |
GB1584826A (en) | 1981-02-18 |
LU75809A1 (fr) | 1978-05-12 |
AT356303B (de) | 1980-04-25 |
FR2364928B1 (fr) | 1981-03-06 |
JPS5337652A (en) | 1978-04-06 |
DE2741067A1 (de) | 1978-03-23 |
BE858709A (fr) | 1978-03-15 |
AU514425B2 (en) | 1981-02-12 |
NL7710086A (nl) | 1978-03-20 |
SE7710337L (sv) | 1978-03-17 |
AU2884877A (en) | 1979-03-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |