FR2361417A1 - Nouveaux derives d'adriamycine et procede pour les preparer - Google Patents

Nouveaux derives d'adriamycine et procede pour les preparer

Info

Publication number
FR2361417A1
FR2361417A1 FR7724508A FR7724508A FR2361417A1 FR 2361417 A1 FR2361417 A1 FR 2361417A1 FR 7724508 A FR7724508 A FR 7724508A FR 7724508 A FR7724508 A FR 7724508A FR 2361417 A1 FR2361417 A1 FR 2361417A1
Authority
FR
France
Prior art keywords
derivatives
preparing
adriamycine
new
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7724508A
Other languages
English (en)
Other versions
FR2361417B1 (fr
Inventor
Pietro Giardino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmaceutici Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia SpA filed Critical Farmaceutici Italia SpA
Publication of FR2361417A1 publication Critical patent/FR2361417A1/fr
Application granted granted Critical
Publication of FR2361417B1 publication Critical patent/FR2361417B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

L'invention a pour objet des dérivés d'adriamycine et un procédé pour les préparer. Ces derivés ont pour formule :
FR7724508A 1976-08-12 1977-08-09 Nouveaux derives d'adriamycine et procede pour les preparer Granted FR2361417A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB33523/76A GB1535080A (en) 1976-08-12 1976-08-12 Naphthacenequinone derivatives

Publications (2)

Publication Number Publication Date
FR2361417A1 true FR2361417A1 (fr) 1978-03-10
FR2361417B1 FR2361417B1 (fr) 1982-10-22

Family

ID=10354073

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7724508A Granted FR2361417A1 (fr) 1976-08-12 1977-08-09 Nouveaux derives d'adriamycine et procede pour les preparer

Country Status (4)

Country Link
JP (1) JPS5377052A (fr)
DE (1) DE2735891A1 (fr)
FR (1) FR2361417A1 (fr)
GB (1) GB1535080A (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0104654A2 (fr) * 1982-09-28 1984-04-04 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Anthracyclineglycosides, leur préparation et les médicaments les contenant

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2135221A1 (en) * 1971-05-04 1972-12-15 Farmaceutici Italia Doxorubicin 14-esters prepn - by treating 14-bromodaunomycin with a salt of the corresp acid
DE2652391A1 (de) * 1975-11-18 1977-05-26 Farmaceutici Italia Daunosaminylanthracyclinone, verfahren zur herstellung und arzneimittel, die diese verbindungen enthalten
US4035566A (en) * 1975-09-25 1977-07-12 Sidney Farber Cancer Institute, Inc. N-trifluoroacetyladriamycin-14-alkanoates and therapeutic compositions containing same

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2135221A1 (en) * 1971-05-04 1972-12-15 Farmaceutici Italia Doxorubicin 14-esters prepn - by treating 14-bromodaunomycin with a salt of the corresp acid
US4035566A (en) * 1975-09-25 1977-07-12 Sidney Farber Cancer Institute, Inc. N-trifluoroacetyladriamycin-14-alkanoates and therapeutic compositions containing same
DE2652391A1 (de) * 1975-11-18 1977-05-26 Farmaceutici Italia Daunosaminylanthracyclinone, verfahren zur herstellung und arzneimittel, die diese verbindungen enthalten
FR2347047A1 (fr) * 1975-11-18 1977-11-04 Farmaceutici Italia Daunosaminyl-anthracyclinones a activite anti-tumorale

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0104654A2 (fr) * 1982-09-28 1984-04-04 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Anthracyclineglycosides, leur préparation et les médicaments les contenant
EP0104654A3 (en) * 1982-09-28 1984-08-15 F. Hoffmann-La Roche & Co. Aktiengesellschaft Anthracycline glycosides, their preparation and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
FR2361417B1 (fr) 1982-10-22
DE2735891A1 (de) 1978-02-16
GB1535080A (en) 1978-12-06
JPS5377052A (en) 1978-07-08

Similar Documents

Publication Publication Date Title
FR2357541A1 (fr) Composes polyeniques et leur procede de preparation
FR2428052A1 (fr) Nouveaux derives de 5-fluoro-(b-uridine ou 2'-desoxy-b-uridine), procede pour les preparer et agents carcinostatiques les renfermant
FR2355028A1 (fr) Procede pour la preparation de glycosides derives d'anthracyclines optiquement actives
FR2369295A1 (fr) Derives
FR2396006A1 (fr) Nouveaux composes a noyau cyclopropanique, procede de preparation et application a la preparation de derives cyclopropaniques a chaine dihalovinyliques
FR2405246A1 (fr) Nouveaux derives de pyrrole, leur procede de preparation et leurs applications en therapeutique
FR2386544A1 (fr) Procede pour la preparation de derives d'imidazodiazepine
FR2388802A1 (fr) Procede de production de derives d'uree et nouveaux produits ainsi obtenus
FR2406630A1 (fr) 2-phenoxy-5-trifluoromethylpyridines et leur procede de preparation
FR2431494A1 (fr) Nouveaux derives du benzofuranne, leur procede de preparation et leur application en therapeutique
FR2371460A1 (fr) Procede de preparation de kanamycine c et de ses derives desoxy
FR2377367A1 (fr) Procede de preparation d'alcoxy-cetones
FR2430942A1 (fr) Preparation de derives o-methyliques d'hydroxyaporphines
FR2370020A2 (fr) Procede de preparation d'alkylphenols
FR2399998A1 (fr) Produit derive de la diphenoxy-1,3 propanone-2, procede pour sa preparation et son application a la realisation d'un medicament
FR2453162A1 (fr) Procede pour la preparation de derives de 4-acetoxy-azetidine-2-one par condensation avec un b-thiocetoester et composes obtenus
FR2361417A1 (fr) Nouveaux derives d'adriamycine et procede pour les preparer
FR2360602A1 (fr) Ethers d'anthracyclines a activite antitumorale et procede pour les preparer
FR2357520A1 (fr) Procede pour preparer des chlorures d'a-chloralcanoyle
FR2391204A1 (fr) Derives de l'anthraquinone, leur procede de preparation et leur application a la teinture de matieres plastiques
FR2406635A1 (fr) Nouveaux derives du benzo(d)thiazole, leur procede de preparation et leurs applications en therapeutique
FR2355831A1 (fr) Derives de benzazocine, leur procede de preparation et leur application therapeutique
FR2453163A1 (fr) Derives de benzothiazole, leur procede de preparation et leurs applications en therapeutique
FR2434147A1 (fr) Procede de production de derives d'oximecarbamate, nouveaux produits ainsi obtenus et leur utilisation comme herbicides
FR2433521A1 (fr) Procede de preparation de derives de benzothiazocine et de benzothiazonine

Legal Events

Date Code Title Description
ST Notification of lapse