FR2361417A1 - NEW ADRIAMYCINE DERIVATIVES AND METHOD FOR PREPARING THEM - Google Patents

NEW ADRIAMYCINE DERIVATIVES AND METHOD FOR PREPARING THEM

Info

Publication number
FR2361417A1
FR2361417A1 FR7724508A FR7724508A FR2361417A1 FR 2361417 A1 FR2361417 A1 FR 2361417A1 FR 7724508 A FR7724508 A FR 7724508A FR 7724508 A FR7724508 A FR 7724508A FR 2361417 A1 FR2361417 A1 FR 2361417A1
Authority
FR
France
Prior art keywords
derivatives
preparing
adriamycine
new
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7724508A
Other languages
French (fr)
Other versions
FR2361417B1 (en
Inventor
Pietro Giardino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmaceutici Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia SpA filed Critical Farmaceutici Italia SpA
Publication of FR2361417A1 publication Critical patent/FR2361417A1/en
Application granted granted Critical
Publication of FR2361417B1 publication Critical patent/FR2361417B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

L'invention a pour objet des dérivés d'adriamycine et un procédé pour les préparer. Ces derivés ont pour formule :The subject of the invention is adriamycin derivatives and a process for preparing them. These derivatives have the following formula:

FR7724508A 1976-08-12 1977-08-09 NEW ADRIAMYCINE DERIVATIVES AND METHOD FOR PREPARING THEM Granted FR2361417A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB33523/76A GB1535080A (en) 1976-08-12 1976-08-12 Naphthacenequinone derivatives

Publications (2)

Publication Number Publication Date
FR2361417A1 true FR2361417A1 (en) 1978-03-10
FR2361417B1 FR2361417B1 (en) 1982-10-22

Family

ID=10354073

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7724508A Granted FR2361417A1 (en) 1976-08-12 1977-08-09 NEW ADRIAMYCINE DERIVATIVES AND METHOD FOR PREPARING THEM

Country Status (4)

Country Link
JP (1) JPS5377052A (en)
DE (1) DE2735891A1 (en)
FR (1) FR2361417A1 (en)
GB (1) GB1535080A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0104654A2 (en) * 1982-09-28 1984-04-04 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Anthracycline glycosides, their preparation and pharmaceutical preparations containing them

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2135221A1 (en) * 1971-05-04 1972-12-15 Farmaceutici Italia Doxorubicin 14-esters prepn - by treating 14-bromodaunomycin with a salt of the corresp acid
DE2652391A1 (en) * 1975-11-18 1977-05-26 Farmaceutici Italia DAUNOSAMINYLANTHRACYCLINONE, METHOD OF MANUFACTURING AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
US4035566A (en) * 1975-09-25 1977-07-12 Sidney Farber Cancer Institute, Inc. N-trifluoroacetyladriamycin-14-alkanoates and therapeutic compositions containing same

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2135221A1 (en) * 1971-05-04 1972-12-15 Farmaceutici Italia Doxorubicin 14-esters prepn - by treating 14-bromodaunomycin with a salt of the corresp acid
US4035566A (en) * 1975-09-25 1977-07-12 Sidney Farber Cancer Institute, Inc. N-trifluoroacetyladriamycin-14-alkanoates and therapeutic compositions containing same
DE2652391A1 (en) * 1975-11-18 1977-05-26 Farmaceutici Italia DAUNOSAMINYLANTHRACYCLINONE, METHOD OF MANUFACTURING AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
FR2347047A1 (en) * 1975-11-18 1977-11-04 Farmaceutici Italia DAUNOSAMINYL-ANTHRACYCLINONES WITH ANTI-TUMOR ACTIVITY

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0104654A2 (en) * 1982-09-28 1984-04-04 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Anthracycline glycosides, their preparation and pharmaceutical preparations containing them
EP0104654A3 (en) * 1982-09-28 1984-08-15 F. Hoffmann-La Roche & Co. Aktiengesellschaft Anthracycline glycosides, their preparation and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
JPS5377052A (en) 1978-07-08
DE2735891A1 (en) 1978-02-16
GB1535080A (en) 1978-12-06
FR2361417B1 (en) 1982-10-22

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Legal Events

Date Code Title Description
ST Notification of lapse