FR2325383A1 - Derives antibiotiques nouveaux de la didesoxy-3',4'kanamycine b et procede pour leur preparation - Google Patents

Derives antibiotiques nouveaux de la didesoxy-3',4'kanamycine b et procede pour leur preparation

Info

Publication number
FR2325383A1
FR2325383A1 FR7629956A FR7629956A FR2325383A1 FR 2325383 A1 FR2325383 A1 FR 2325383A1 FR 7629956 A FR7629956 A FR 7629956A FR 7629956 A FR7629956 A FR 7629956A FR 2325383 A1 FR2325383 A1 FR 2325383A1
Authority
FR
France
Prior art keywords
didesoxy
kanamycin
preparation
new antibiotic
antibiotic derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7629956A
Other languages
English (en)
Other versions
FR2325383B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Publication of FR2325383A1 publication Critical patent/FR2325383A1/fr
Application granted granted Critical
Publication of FR2325383B1 publication Critical patent/FR2325383B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C07H15/236—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
FR7629956A 1975-09-25 1976-09-24 Derives antibiotiques nouveaux de la didesoxy-3',4'kanamycine b et procede pour leur preparation Granted FR2325383A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP50114883A JPS5239653A (en) 1975-09-25 1975-09-25 Process for preparing antibiotics of 3',4'-dideoxykanamycin b derivati ves

Publications (2)

Publication Number Publication Date
FR2325383A1 true FR2325383A1 (fr) 1977-04-22
FR2325383B1 FR2325383B1 (fr) 1980-09-26

Family

ID=14649050

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7629956A Granted FR2325383A1 (fr) 1975-09-25 1976-09-24 Derives antibiotiques nouveaux de la didesoxy-3',4'kanamycine b et procede pour leur preparation

Country Status (5)

Country Link
US (1) US4091202A (fr)
JP (1) JPS5239653A (fr)
DE (1) DE2641388C3 (fr)
FR (1) FR2325383A1 (fr)
GB (1) GB1507118A (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5740496A (en) * 1980-08-22 1982-03-06 Microbial Chem Res Found Low toxic derivative of istamycin antibiotic
JPS58128395A (ja) * 1982-01-27 1983-07-30 Microbial Chem Res Found ３−０−デメチルイスタマイシンｂの低毒性誘導体
US4567165A (en) * 1984-05-08 1986-01-28 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai N-Methanesulfonic acid derivatives of 3-demethoxyistamycin B
US6310073B1 (en) * 1998-07-28 2001-10-30 Queen's University At Kingston Methods and compositions to treat glycosaminoglycan-associated molecular interactions
BRPI0819319B8 (pt) 2007-11-21 2021-05-25 Achaogen Inc análogos de aminoglicosídeo antibacteriano
WO2010132765A2 (fr) 2009-05-15 2010-11-18 Achaogen, Inc. Analogues d'aminoglycoside antibactériens
WO2010132768A1 (fr) 2009-05-15 2010-11-18 Achaogen, Inc. Dérivés antibactériens de sisomicine
WO2010132757A2 (fr) 2009-05-15 2010-11-18 Achaogen, Inc. Analogues d'aminoglycoside antibactériens
WO2010132759A1 (fr) 2009-05-15 2010-11-18 Achaogen, Inc. Dérivés antibactériens de la dibékacine
WO2010132760A1 (fr) 2009-05-15 2010-11-18 Achaogen, Inc. Dérivés antibactériens de tobramycine

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2599950A (en) * 1947-04-30 1952-06-10 American Cyanamid Co Method of preparing polymyxin
US2931798A (en) * 1956-09-05 1960-04-05 Umezawa Hamao Kanamycin and processes for the preparation thereof
FR1272911A (fr) * 1958-07-23 1961-10-06 Soc Ind Fab Antibiotiques Sifa Procédé de préparation de nouveaux dérivés d'antibiotiques basiques
GB933702A (en) * 1958-12-12 1963-08-08 Sumio Umezawa Process for the production of n-methanesulfonic acid derivatives of kanamycin
GB957433A (en) * 1959-09-08 1964-05-06 Sumio Umezawa Preparation of kanamycin-n,n-dimethane sulphonic acid
GB896774A (en) * 1960-01-29 1962-05-16 Parke Davis & Co Derivatives of paromomycin and methods for their production
GB902992A (en) * 1960-03-18 1962-08-09 Farmaceutici Italia Antibiotic derivatives
US3061515A (en) * 1960-05-09 1962-10-30 Bristol Myers Co Methane sulfonates of telomycins
US3205137A (en) * 1963-03-19 1965-09-07 Warner Lambert Pharmaceutical Bacitracin derivatives
JPS507595B1 (fr) * 1970-07-29 1975-03-27
US3840535A (en) * 1972-08-23 1974-10-08 Bristol Myers Co Dimethanesulfonates of certain 7-(o-aminomethylphenylacetamido)-3-((heterocyclylthio)methyl)-ceph-3-em-4-carboxylic acids
US4001208A (en) * 1972-10-06 1977-01-04 Zaidan Hojin Biseibutsu Kagaku Kenkyo Kai 1-N-[(S)-α-hydroxy-ω-aminoacyl]

Also Published As

Publication number Publication date
DE2641388B2 (de) 1980-05-29
JPS5239653A (en) 1977-03-28
DE2641388C3 (de) 1981-02-05
GB1507118A (en) 1978-04-12
DE2641388A1 (de) 1977-03-31
US4091202A (en) 1978-05-23
FR2325383B1 (fr) 1980-09-26
JPS5736917B2 (fr) 1982-08-06

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Legal Events

Date Code Title Description
ST Notification of lapse