FR2273542A1 - 8-thiomethylergolines - Google Patents

8-thiomethylergolines

Info

Publication number: FR2273542A1
Authority: FR; France
Prior art keywords: thiomethylergolines
Prior art date: 1974-06-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

FR7517652A

Other languages

English (en)

French (fr)

Other versions

FR2273542B1 (nl

Inventor

Edmund Carl Kornfeld

Nicholas James Bach

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Eli Lilly and Co

Original Assignee

Eli Lilly and Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-06-06

Filing date

1975-06-05

Publication date

1976-01-02

1975-06-05 Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co

1976-01-02 Publication of FR2273542A1 publication Critical patent/FR2273542A1/fr

1978-10-06 Application granted granted Critical

1978-10-06 Publication of FR2273542B1 publication Critical patent/FR2273542B1/fr

Status Granted legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

FR7517652A 1974-06-06 1975-06-05 8-thiomethylergolines Granted FR2273542A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US477136A US3901894A (en)	1974-06-06	1974-06-06	8-thiomethylergolines

Publications (2)

Publication Number	Publication Date
FR2273542A1 true FR2273542A1 (fr)	1976-01-02
FR2273542B1 FR2273542B1 (nl)	1978-10-06

Family

ID=23894677

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FR7517652A Granted FR2273542A1 (fr)	1974-06-06	1975-06-05	8-thiomethylergolines

Country Status (27)

Country	Link
US (1)	US3901894A (nl)
JP (1)	JPS582946B2 (nl)
AR (1)	AR210736A1 (nl)
AT (1)	AT344333B (nl)
AU (1)	AU507574B2 (nl)
BE (1)	BE829887A (nl)
BG (1)	BG24812A3 (nl)
CA (1)	CA1071623A (nl)
CH (1)	CH617196A5 (nl)
CS (1)	CS199591B2 (nl)
DD (1)	DD120438A5 (nl)
DE (1)	DE2524575A1 (nl)
DK (1)	DK144160C (nl)
ES (1)	ES438313A1 (nl)
FR (1)	FR2273542A1 (nl)
GB (1)	GB1505296A (nl)
HU (1)	HU173590B (nl)
IE (1)	IE41474B1 (nl)
IL (1)	IL47424A (nl)
NL (1)	NL180911C (nl)
PH (1)	PH10992A (nl)
PL (1)	PL95738B1 (nl)
RO (1)	RO77543A (nl)
SE (1)	SE420095B (nl)
SU (1)	SU613724A3 (nl)
YU (1)	YU145575A (nl)
ZA (1)	ZA753638B (nl)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2471381A1 (fr) *	1979-12-06	1981-06-19	Erba Farmitalia	Derives de l'ergoline, procede pour les preparer et leur emploi comme medicaments
EP0094305B1 (fr) *	1982-05-12	1988-01-13	Roussel-Uclaf	Nouveaux dérivés de l'acide 9-oxalysergique, leurs sels, procédé et intermédiaires de préparation, application à titre de médicaments et compositions les renfermant

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4147789A (en) *	1974-03-14	1979-04-03	Sandoz Ltd.	6-Methyl-8-thiomethyl-ergolene derivatives
US3959288A (en) *	1974-12-13	1976-05-25	Eli Lilly And Company	8-Oxymethylergolines and process therefor
JPS5283894A (en) *	1976-01-01	1977-07-13	Lilly Co Eli	88thiomethyl ergoline
GB1549829A (en) *	1976-05-26	1979-08-08	Farmaceutici Italia	10'-methoxy-1',6'-dimethylergoline-8'-beta-methyl-amino(or thio)-pyrazines
IT1192260B (it) *	1977-07-05	1988-03-31	Simes	Derivati di ergoline-2-tioeteri e loro solfossidi
US4166182A (en) *	1978-02-08	1979-08-28	Eli Lilly And Company	6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4180582A (en) *	1978-02-08	1979-12-25	Eli Lilly And Company	6-n-Propyl-8-methoxy-methyl or methylmercaptomethylergolines and related compounds as prolactin inhibitors and to treat Parkinson's syndrome
US4202979A (en) *	1979-01-11	1980-05-13	Eli Lilly And Company	6-Ethyl(or allyl)-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4246265A (en) *	1979-10-01	1981-01-20	Eli Lilly And Company	6-n-Propyl-8α-methoxymethyl or methylmercaptomethylergolines and related compounds
DE3216870A1 (de) *	1982-05-03	1983-11-03	Schering AG, 1000 Berlin und 4709 Bergkamen	Pharmazeutische zubereitungen mit zytostatischer wirkung
CH649998A5 (de) *	1982-08-09	1985-06-28	Sandoz Ag	Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff.
GB8427536D0 (en) *	1984-10-31	1984-12-05	Lilly Industries Ltd	Ergoline derivatives
US4675322A (en) *	1984-12-10	1987-06-23	Eli Lilly And Company	1-Substituted-6-n-propyl-8β-methylthio-methylergolines
US4801712A (en) *	1985-06-24	1989-01-31	Eli Lilly And Company	2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity
FR2589734B1 (fr) *	1985-11-13	1988-09-02	Roussel Uclaf	Utilisation de derives de l'ergoline a l'obtention d'un medicament a visee geriatrique
HU196394B (en) *	1986-06-27	1988-11-28	Richter Gedeon Vegyeszet	Process for preparing 2-halogenated ergoline derivatives
CA2449634C (en) *	2001-06-08	2011-08-02	Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R	Somatostatin-dopamine chimeric analogs
EP1485382B1 (en) *	2002-03-15	2008-11-19	Antibioticos S.p.A.	Process for the synthesis of pergolide
JP2016503402A (ja)	2012-11-01	2016-02-04	イプセンファルマソシエテパールアクシオンサンプリフィエＩｐｓｅｎＰｈａｒｍａＳ．Ａ．Ｓ．	ソマトスタチン類似体及びそのダイマー
TWI523863B (zh)	2012-11-01	2016-03-01	艾普森藥品公司	體抑素－多巴胺嵌合體類似物
WO2019234069A1 (en)	2018-06-08	2019-12-12	Boehringer Ingelheim Vetmedica Gmbh	Liquid pharmaceutical compositions comprising pergolide

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE712054A (nl) *	1967-03-16	1968-07-15
DE1935556A1 (de) *	1969-07-12	1971-01-21	Hoechst Ag	Verfahren zur Herstellung von Lysergol
JPS5012398A (nl) *	1973-06-08	1975-02-07

1974
- 1974-06-06 US US477136A patent/US3901894A/en not_active Expired - Lifetime
1975
- 1975-05-16 JP JP50059191A patent/JPS582946B2/ja not_active Expired
- 1975-06-03 CA CA228,332A patent/CA1071623A/en not_active Expired
- 1975-06-03 CS CS753882A patent/CS199591B2/cs unknown
- 1975-06-03 GB GB23869/75A patent/GB1505296A/en not_active Expired
- 1975-06-03 IE IE1221/75A patent/IE41474B1/en unknown
- 1975-06-03 NL NLAANVRAGE7506584,A patent/NL180911C/nl not_active IP Right Cessation
- 1975-06-03 HU HU75EI623A patent/HU173590B/hu unknown
- 1975-06-03 DE DE19752524575 patent/DE2524575A1/de not_active Ceased
- 1975-06-03 PH PH17225A patent/PH10992A/en unknown
- 1975-06-03 SE SE7506327A patent/SE420095B/xx not_active IP Right Cessation
- 1975-06-04 PL PL1975180897A patent/PL95738B1/pl unknown
- 1975-06-04 DK DK249975A patent/DK144160C/da not_active IP Right Cessation
- 1975-06-04 BG BG7500030188A patent/BG24812A3/xx unknown
- 1975-06-04 AU AU81827/75A patent/AU507574B2/en not_active Expired
- 1975-06-04 IL IL47424A patent/IL47424A/xx unknown
- 1975-06-05 FR FR7517652A patent/FR2273542A1/fr active Granted
- 1975-06-05 BE BE1006709A patent/BE829887A/xx not_active IP Right Cessation
- 1975-06-05 YU YU01455/75A patent/YU145575A/xx unknown
- 1975-06-05 AT AT427975A patent/AT344333B/de not_active IP Right Cessation
- 1975-06-05 RO RO7582445A patent/RO77543A/ro unknown
- 1975-06-05 SU SU752140862A patent/SU613724A3/ru active
- 1975-06-05 ZA ZA3638A patent/ZA753638B/xx unknown
- 1975-06-06 CH CH731075A patent/CH617196A5/de not_active IP Right Cessation
- 1975-06-06 AR AR259118A patent/AR210736A1/es active
- 1975-06-06 ES ES438313A patent/ES438313A1/es not_active Expired
1976
- 1976-06-05 DD DD186472A patent/DD120438A5/xx unknown

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2471381A1 (fr) *	1979-12-06	1981-06-19	Erba Farmitalia	Derives de l'ergoline, procede pour les preparer et leur emploi comme medicaments
EP0094305B1 (fr) *	1982-05-12	1988-01-13	Roussel-Uclaf	Nouveaux dérivés de l'acide 9-oxalysergique, leurs sels, procédé et intermédiaires de préparation, application à titre de médicaments et compositions les renfermant

Also Published As

Publication number	Publication date
BE829887A (fr)	1975-12-05
SE7506327L (sv)	1975-12-08
DK144160C (da)	1982-06-07
SU613724A3 (ru)	1978-06-30
DK249975A (da)	1975-12-07
PH10992A (en)	1977-10-20
JPS50160300A (nl)	1975-12-25
JPS582946B2 (ja)	1983-01-19
GB1505296A (en)	1978-03-30
PL95738B1 (pl)	1977-11-30
AU507574B2 (en)	1980-02-21
DE2524575A1 (de)	1975-12-18
IL47424A (en)	1979-11-30
IE41474L (en)	1975-12-06
AU8182775A (en)	1976-12-09
NL7506584A (nl)	1975-12-09
ES438313A1 (es)	1977-05-16
RO77543A (ro)	1982-02-26
NL180911B (nl)	1986-12-16
FR2273542B1 (nl)	1978-10-06
BG24812A3 (en)	1978-05-12
CS199591B2 (en)	1980-07-31
IL47424A0 (en)	1975-08-31
AR210736A1 (es)	1977-09-15
CH617196A5 (nl)	1980-05-14
DD120438A5 (nl)	1976-06-12
SE420095B (sv)	1981-09-14
CA1071623A (en)	1980-02-12
AT344333B (de)	1978-07-10
US3901894A (en)	1975-08-26
ZA753638B (en)	1977-01-26
ATA427975A (de)	1977-11-15
NL180911C (nl)	1987-05-18
DK144160B (da)	1981-12-28
IE41474B1 (en)	1980-01-16
HU173590B (hu)	1979-06-28
YU145575A (en)	1982-02-28

Legal Events

Date	Code	Title	Description
1992-04-30	ST	Notification of lapse

Publication	Publication Date	Title
BE824255A (fr)	1975-07-09	Aryloxyphenylpropylamines
AT332977B (de)	1976-10-25	Deodorantien
AT332978B (de)	1976-10-25	Deodorantien
BE824920A (fr)	1975-05-15	Servo-distributeur
BE827298A (fr)	1975-09-29	Acylurfidocephalosporines
BE827404A (fr)	1975-09-29	Automatische c02 - gehaltemeter
AT338025B (de)	1977-07-25	Samaschine
AT340188B (de)	1977-11-25	Samaschine
AT338077B (de)	1977-07-25	Handmuhle
BE826270A (fr)	1975-09-04	Brandkraan
BE826556A (fr)	1975-09-11	Haveuse
BE828211A (fr)	1975-10-22	Vincadioline
AT345679B (de)	1978-09-25	Kettenschloss
AT335386B (de)	1977-03-10	Kettbaum
BE824358R (fr)	1975-05-02	Phenolethanolamine acylff
AT342532B (de)	1978-04-10	Sparkerze
BE827338A (fr)	1975-09-29	Trifluoroethylanilines
JPS511034A (ja)	1976-01-07	Kiokusochiseigyohoshiki
AT339823B (de)	1977-11-10	Mullcontainer
AT337487B (de)	1977-07-11	Pfeifenreiber
BE823015A (fr)	1975-04-01	Sorbetiere
BE829863A (fr)	1975-10-01	Petard
BE828179A (fr)	1975-08-18	Snijmachine
BE825385A (fr)	1975-08-11	Elektrofotografisch filmdeel
BE826873A (fr)	1975-09-19	Alkylsulfonylphenoxypropanolamines

FR2273542A1 - 8-thiomethylergolines - Google Patents

Info

Links

Classifications

Landscapes

Applications Claiming Priority (1)

Publications (2)

Family

ID=23894677

Family Applications (1)

Country Status (27)

Cited By (2)

Families Citing this family (21)

Family Cites Families (3)

Cited By (2)

Also Published As

Similar Documents

Legal Events