FR2273542A1 - 8-THIOMETHYLERGOLINES - Google Patents

8-THIOMETHYLERGOLINES

Info

Publication number
FR2273542A1
FR2273542A1 FR7517652A FR7517652A FR2273542A1 FR 2273542 A1 FR2273542 A1 FR 2273542A1 FR 7517652 A FR7517652 A FR 7517652A FR 7517652 A FR7517652 A FR 7517652A FR 2273542 A1 FR2273542 A1 FR 2273542A1
Authority
FR
France
Prior art keywords
thiomethylergolines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7517652A
Other languages
French (fr)
Other versions
FR2273542B1 (en
Inventor
Edmund Carl Kornfeld
Nicholas James Bach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of FR2273542A1 publication Critical patent/FR2273542A1/en
Application granted granted Critical
Publication of FR2273542B1 publication Critical patent/FR2273542B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7517652A 1974-06-06 1975-06-05 8-THIOMETHYLERGOLINES Granted FR2273542A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US477136A US3901894A (en) 1974-06-06 1974-06-06 8-thiomethylergolines

Publications (2)

Publication Number Publication Date
FR2273542A1 true FR2273542A1 (en) 1976-01-02
FR2273542B1 FR2273542B1 (en) 1978-10-06

Family

ID=23894677

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7517652A Granted FR2273542A1 (en) 1974-06-06 1975-06-05 8-THIOMETHYLERGOLINES

Country Status (27)

Country Link
US (1) US3901894A (en)
JP (1) JPS582946B2 (en)
AR (1) AR210736A1 (en)
AT (1) AT344333B (en)
AU (1) AU507574B2 (en)
BE (1) BE829887A (en)
BG (1) BG24812A3 (en)
CA (1) CA1071623A (en)
CH (1) CH617196A5 (en)
CS (1) CS199591B2 (en)
DD (1) DD120438A5 (en)
DE (1) DE2524575A1 (en)
DK (1) DK144160C (en)
ES (1) ES438313A1 (en)
FR (1) FR2273542A1 (en)
GB (1) GB1505296A (en)
HU (1) HU173590B (en)
IE (1) IE41474B1 (en)
IL (1) IL47424A (en)
NL (1) NL180911C (en)
PH (1) PH10992A (en)
PL (1) PL95738B1 (en)
RO (1) RO77543A (en)
SE (1) SE420095B (en)
SU (1) SU613724A3 (en)
YU (1) YU145575A (en)
ZA (1) ZA753638B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2471381A1 (en) * 1979-12-06 1981-06-19 Erba Farmitalia ERGOLINE DERIVATIVES, PROCESS FOR PREPARING THEM AND THEIR USE AS MEDICAMENTS
EP0094305B1 (en) * 1982-05-12 1988-01-13 Roussel-Uclaf 9-oxalysergic-acid derivatives, their salts, process and intermediates for their preparation, their use as pharmaceutical preparations and compositions containing them

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4147789A (en) * 1974-03-14 1979-04-03 Sandoz Ltd. 6-Methyl-8-thiomethyl-ergolene derivatives
US3959288A (en) * 1974-12-13 1976-05-25 Eli Lilly And Company 8-Oxymethylergolines and process therefor
JPS5283894A (en) * 1976-01-01 1977-07-13 Lilly Co Eli 88thiomethyl ergoline
GB1549829A (en) * 1976-05-26 1979-08-08 Farmaceutici Italia 10'-methoxy-1',6'-dimethylergoline-8'-beta-methyl-amino(or thio)-pyrazines
IT1192260B (en) * 1977-07-05 1988-03-31 Simes ERGOLINE-2-THIOETHERS AND THEIR SULPHOXIDES DERIVATIVES
US4180582A (en) * 1978-02-08 1979-12-25 Eli Lilly And Company 6-n-Propyl-8-methoxy-methyl or methylmercaptomethylergolines and related compounds as prolactin inhibitors and to treat Parkinson's syndrome
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4202979A (en) * 1979-01-11 1980-05-13 Eli Lilly And Company 6-Ethyl(or allyl)-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4246265A (en) * 1979-10-01 1981-01-20 Eli Lilly And Company 6-n-Propyl-8α-methoxymethyl or methylmercaptomethylergolines and related compounds
DE3216870A1 (en) * 1982-05-03 1983-11-03 Schering AG, 1000 Berlin und 4709 Bergkamen PHARMACEUTICAL PREPARATIONS WITH A CYTOSTATIC EFFECT
CH649998A5 (en) * 1982-08-09 1985-06-28 Sandoz Ag ERGOL DERIVATIVES, A METHOD FOR THEIR PRODUCTION AND HEALING AGENTS, CONTAINING THESE ERGOL DERIVATIVES AS AN ACTIVE SUBSTANCE.
GB8427536D0 (en) * 1984-10-31 1984-12-05 Lilly Industries Ltd Ergoline derivatives
US4675322A (en) * 1984-12-10 1987-06-23 Eli Lilly And Company 1-Substituted-6-n-propyl-8β-methylthio-methylergolines
US4801712A (en) * 1985-06-24 1989-01-31 Eli Lilly And Company 2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity
FR2589734B1 (en) * 1985-11-13 1988-09-02 Roussel Uclaf USE OF ERGOLIN DERIVATIVES FOR OBTAINING A GERIATRIC MEDICINE
HU196394B (en) * 1986-06-27 1988-11-28 Richter Gedeon Vegyeszet Process for preparing 2-halogenated ergoline derivatives
BR0210915A (en) * 2001-06-08 2004-06-08 Sod Conseils Rech Applic Chimeric Somatostatin-Dopamine Analogs
EP1485382B1 (en) * 2002-03-15 2008-11-19 Antibioticos S.p.A. Process for the synthesis of pergolide
TWI523863B (en) 2012-11-01 2016-03-01 艾普森藥品公司 Somatostatin-dopamine chimeric analogs
RU2015120570A (en) 2012-11-01 2016-12-20 Ипсен Фарма С.А.С. SOMATOSTATIN ANALOGUES AND THEIR DIMERS
US20190374534A1 (en) 2018-06-08 2019-12-12 Boehringer Ingelheim Vetmedica Gmbh Liquid pharmaceutical compositions comprising pergolide

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE712054A (en) * 1967-03-16 1968-07-15
DE1935556A1 (en) * 1969-07-12 1971-01-21 Hoechst Ag Process for the production of lysergol
JPS5012398A (en) * 1973-06-08 1975-02-07

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2471381A1 (en) * 1979-12-06 1981-06-19 Erba Farmitalia ERGOLINE DERIVATIVES, PROCESS FOR PREPARING THEM AND THEIR USE AS MEDICAMENTS
EP0094305B1 (en) * 1982-05-12 1988-01-13 Roussel-Uclaf 9-oxalysergic-acid derivatives, their salts, process and intermediates for their preparation, their use as pharmaceutical preparations and compositions containing them

Also Published As

Publication number Publication date
AR210736A1 (en) 1977-09-15
DD120438A5 (en) 1976-06-12
NL180911C (en) 1987-05-18
PH10992A (en) 1977-10-20
ZA753638B (en) 1977-01-26
CS199591B2 (en) 1980-07-31
JPS50160300A (en) 1975-12-25
AU8182775A (en) 1976-12-09
IL47424A (en) 1979-11-30
NL7506584A (en) 1975-12-09
NL180911B (en) 1986-12-16
ES438313A1 (en) 1977-05-16
DK144160C (en) 1982-06-07
RO77543A (en) 1982-02-26
JPS582946B2 (en) 1983-01-19
AT344333B (en) 1978-07-10
FR2273542B1 (en) 1978-10-06
SE7506327L (en) 1975-12-08
DK249975A (en) 1975-12-07
BE829887A (en) 1975-12-05
CA1071623A (en) 1980-02-12
IE41474B1 (en) 1980-01-16
AU507574B2 (en) 1980-02-21
CH617196A5 (en) 1980-05-14
GB1505296A (en) 1978-03-30
YU145575A (en) 1982-02-28
DK144160B (en) 1981-12-28
SU613724A3 (en) 1978-06-30
US3901894A (en) 1975-08-26
SE420095B (en) 1981-09-14
HU173590B (en) 1979-06-28
BG24812A3 (en) 1978-05-12
PL95738B1 (en) 1977-11-30
IL47424A0 (en) 1975-08-31
DE2524575A1 (en) 1975-12-18
IE41474L (en) 1975-12-06
ATA427975A (en) 1977-11-15

Similar Documents

Publication Publication Date Title
BE824255A (en) ARYLOXYPHENYLPROPYLAMINES
AT332977B (en) DEODORANTIES
AT332978B (en) DEODORANTIES
BE824920A (en) SERVO-DISTRIBUTOR
BE827298A (en) ACYLURFIDOCEPHALOSPORINS
BE827404A (en) AUTOMATISCHE C02 - GEHALTEMETER
AT340188B (en) SAMASCHINE
ATA613675A (en) SAMASCHINE
AT338077B (en) HANDMILL
BE826270A (en) BRANDKRAAN
BE826556A (en) HAVEUSE
BE828211A (en) VINCADIOLINE
AT342532B (en) SPARKERZE
AT345679B (en) CHAINLOCK
BE824358R (en) PHENOLETHANOLAMINE ACYLFF
AT335386B (en) KETTBAUM
BE827338A (en) TRIFLUOROETHYLANILINES
JPS5110054A (en) SHOKUBUTSUI KUSEIYOTANSANGASUKYOKYUSOCHI
AT339823B (en) MULLCONTAINER
AT337487B (en) PIPEBREAKER
BE826873A (en) ALKYLSULFONYLPHENOXYPROPANOLAMINES
BE828179A (en) SNIJMACHINE
BE829863A (en) PETARD
BE825385A (en) ELEKTROFOTOGRAFISCH FILMDEEL
BE823015A (en) SORBETIERE

Legal Events

Date Code Title Description
ST Notification of lapse