FR2167217A1 - Isoindolino-quinoline derivs - useful as tranquillizers and anticonvulsants - Google Patents
Isoindolino-quinoline derivs - useful as tranquillizers and anticonvulsantsInfo
- Publication number
- FR2167217A1 FR2167217A1 FR7200650A FR7200650A FR2167217A1 FR 2167217 A1 FR2167217 A1 FR 2167217A1 FR 7200650 A FR7200650 A FR 7200650A FR 7200650 A FR7200650 A FR 7200650A FR 2167217 A1 FR2167217 A1 FR 2167217A1
- Authority
- FR
- France
- Prior art keywords
- isoindolino
- tranquillizers
- anticonvulsants
- useful
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- G—PHYSICS
- G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
- G03G—ELECTROGRAPHY; ELECTROPHOTOGRAPHY; MAGNETOGRAPHY
- G03G15/00—Apparatus for electrographic processes using a charge pattern
- G03G15/14—Apparatus for electrographic processes using a charge pattern for transferring a pattern to a second base
- G03G15/16—Apparatus for electrographic processes using a charge pattern for transferring a pattern to a second base of a toner pattern, e.g. a powder pattern, e.g. magnetic transfer
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
Title derivs are cpds of formula (I) (where X is halogen, 1-4C alkyl, 1-4C alkoxy, NO2 and/or H; Y is halogen, 1-4C alkyl, 1-4C alkoxy, CN, NO2 and/or H; and n is 0 or 1) and their acid addition salts. (I) in which n is 0 are obtained by reacting an alkali salt of a cpd of formula (II) with 1-chlorocarbonyl-4-methylpiperazine or by reacting a cpd of formula (II. -OH=-OCOOAr) (where Ar is opt. substituted aryl) with 1-methylpiperazine, and may be converted into (I) in which n is 1 by oxidn.
Priority Applications (39)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BE793851D BE793851A (en) | 1972-01-10 | NEW ISOINDOLINE DERIVATIVES, THEIR PREPARATION AND THE MEDICINAL COMPOSITIONS CONTAINING THEM | |
FR7200650A FR2167217A1 (en) | 1972-01-10 | 1972-01-10 | Isoindolino-quinoline derivs - useful as tranquillizers and anticonvulsants |
PL1972175094A PL92423B1 (en) | 1972-01-10 | 1972-12-28 | Isoindolino-quinoline derivs - useful as tranquillizers and anticonvulsants[FR2167217A1] |
PL1972159839A PL89131B1 (en) | 1972-01-10 | 1972-12-28 | Isoindolino-quinoline derivs - useful as tranquillizers and anticonvulsants[FR2167217A1] |
US319879A US3884921A (en) | 1972-01-10 | 1972-12-29 | Isoindoline derivatives |
NLAANVRAGE7300024,A NL178690C (en) | 1972-01-10 | 1973-01-02 | METHOD FOR PREPARING A PHARMACEUTICAL PREPARATION WITH A CALMING AND ANTI-COMPOSITIVE ACTION, AND A METHOD FOR PREPARING A COMPOUND, SUITABLE FOR USE IN THIS METHOD |
AU50876/73A AU468083B2 (en) | 1972-01-10 | 1973-01-08 | Isoindoline derivatives |
JP475773A JPS5610315B2 (en) | 1972-01-10 | 1973-01-08 | |
GB92873A GB1367589A (en) | 1972-01-10 | 1973-01-08 | Isoindoline derivatives |
IE24/73A IE37088B1 (en) | 1972-01-10 | 1973-01-08 | Isoindoline derivatives |
PH14239*UA PH9482A (en) | 1972-01-10 | 1973-01-08 | 3-(4-methylpiperazin-1-yl)carbonyloxy-2-quinol-2-yl isoindolin-1-one derivatives |
ZA730118A ZA73118B (en) | 1972-01-10 | 1973-01-08 | Isoindoline derivatives |
DK11273AA DK138117B (en) | 1972-01-10 | 1973-01-09 | Analogous process for the preparation of isoindoline derivatives or acid addition salts thereof. |
SE7300262A SE384510B (en) | 1972-01-10 | 1973-01-09 | PROCEDURE FOR PREPARING NEW ISOINDOLINPIPERAZINE DERIVATIVES |
CH22673A CH554353A (en) | 1972-01-10 | 1973-01-09 | PROCESS FOR THE PREPARATION OF NEW DERIVATIVES OF ISOINDOLINE. |
CA160,876A CA991184A (en) | 1972-01-10 | 1973-01-09 | Isoindoline derivatives, their preparation and pharmaceutical compositions containing them |
LU66810A LU66810A1 (en) | 1972-01-10 | 1973-01-09 | |
HURO693A HU164822B (en) | 1972-01-10 | 1973-01-09 | |
IL41259A IL41259A (en) | 1972-01-10 | 1973-01-09 | 3-((4-methyl-1-piperazinyl carbonyl)oxy)-2-(2-quinolyl)-1-isoindoline derivatives,process for their preparation and pharmaceutical compositions containing the same |
AR246040A AR197485A1 (en) | 1972-01-10 | 1973-01-09 | PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF ISOINDOLINONE |
CH912874A CH554354A (en) | 1972-01-10 | 1973-01-09 | PROCESS FOR THE PREPARATION OF NEW DERIVATIVES OF ISOINDOLINE. |
YU40/73A YU35765B (en) | 1972-01-10 | 1973-01-09 | Process for obtaining novel isoindoline derivatives |
NO84/73A NO136840C (en) | 1972-01-10 | 1973-01-09 | ANALOGICAL PROCEDURES FOR THE PREPARATION OF NEW, THERAPEUTICALLY ACTIVE DERIVATIVES OF ISOINDOLIN |
CS7600006360A CS181748B2 (en) | 1972-01-10 | 1973-01-10 | Method of producing derivatives of isoindoline |
OA54803A OA04286A (en) | 1972-01-10 | 1973-01-10 | New derivatives of isoindoline and their preparation. |
ES410490A ES410490A1 (en) | 1972-01-10 | 1973-01-10 | Manufacture of isoindoline derivative |
AT18773A AT325622B (en) | 1972-01-10 | 1973-01-10 | PROCESS FOR THE PREPARATION OF NEW ISOINDOLINONE DERIVATIVES AND THEIR ACID ADDITION SALTS |
CS7300000201A CS181717B2 (en) | 1972-01-10 | 1973-01-10 | Process for preparing derivatives of isoindoline |
DD168163A DD102697A5 (en) | 1972-01-10 | 1973-01-10 | |
AT528274A AT325626B (en) | 1972-01-10 | 1973-01-10 | PROCESS FOR THE PRODUCTION OF NEW ISOINDOLINONE DERIVATIVES AND THEIR ACID ADDITION SALTS |
SU1874587A SU488409A3 (en) | 1972-01-10 | 1973-01-10 | The method of obtaining derivatives of isoindoline or their salts |
FI67/73A FI55198C (en) | 1972-01-10 | 1973-01-10 | FOERFARANDE FOER FRAMSTAELLNING AV NYA TERAPEUTISKT AKTIVA ISOINDOLINDERIVAT |
DE2301069A DE2301069C2 (en) | 1972-01-10 | 1973-01-10 | New isoindolinone derivatives, their preparation and pharmaceutical compositions containing them |
ES410489A ES410489A1 (en) | 1972-01-10 | 1973-01-10 | Manufacture of isoindoline derivative |
AR249716A AR202800A1 (en) | 1972-01-10 | 1973-08-23 | PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF <(QUINOLIL-2) -2 OXO -1 ISOINDOLINYL-3> OXICARBONIL-4 METHYL-1 PIPERAZINE |
SU2032660A SU499805A3 (en) | 1972-01-10 | 1974-06-17 | The method of obtaining derivatives of isoindoline or their salts |
YU1847/79A YU35766B (en) | 1972-01-10 | 1979-07-30 | Process for obtaining novel isoindoline derivatives |
YU01874/79A YU187473A (en) | 1972-01-10 | 1979-07-30 | Process for preparing novel isoindoline derivatives |
JP9280780A JPS5622780A (en) | 1972-01-10 | 1980-07-09 | Manufacture of isoindoline derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7200650A FR2167217A1 (en) | 1972-01-10 | 1972-01-10 | Isoindolino-quinoline derivs - useful as tranquillizers and anticonvulsants |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2167217A1 true FR2167217A1 (en) | 1973-08-24 |
FR2167217B1 FR2167217B1 (en) | 1975-06-13 |
Family
ID=9091655
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7200650A Granted FR2167217A1 (en) | 1972-01-10 | 1972-01-10 | Isoindolino-quinoline derivs - useful as tranquillizers and anticonvulsants |
Country Status (10)
Country | Link |
---|---|
JP (1) | JPS5622780A (en) |
AR (1) | AR202800A1 (en) |
AU (1) | AU468083B2 (en) |
CS (2) | CS181748B2 (en) |
ES (2) | ES410490A1 (en) |
FR (1) | FR2167217A1 (en) |
PL (2) | PL92423B1 (en) |
SU (2) | SU488409A3 (en) |
YU (2) | YU35766B (en) |
ZA (1) | ZA73118B (en) |
-
1972
- 1972-01-10 FR FR7200650A patent/FR2167217A1/en active Granted
- 1972-12-28 PL PL1972175094A patent/PL92423B1/en unknown
- 1972-12-28 PL PL1972159839A patent/PL89131B1/en unknown
-
1973
- 1973-01-08 ZA ZA730118A patent/ZA73118B/en unknown
- 1973-01-08 AU AU50876/73A patent/AU468083B2/en not_active Expired
- 1973-01-10 CS CS7600006360A patent/CS181748B2/en unknown
- 1973-01-10 ES ES410490A patent/ES410490A1/en not_active Expired
- 1973-01-10 ES ES410489A patent/ES410489A1/en not_active Expired
- 1973-01-10 CS CS7300000201A patent/CS181717B2/en unknown
- 1973-01-10 SU SU1874587A patent/SU488409A3/en active
- 1973-08-23 AR AR249716A patent/AR202800A1/en active
-
1974
- 1974-06-17 SU SU2032660A patent/SU499805A3/en active
-
1979
- 1979-07-30 YU YU1847/79A patent/YU35766B/en unknown
- 1979-07-30 YU YU01874/79A patent/YU187473A/en unknown
-
1980
- 1980-07-09 JP JP9280780A patent/JPS5622780A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
YU35766B (en) | 1981-06-30 |
SU499805A3 (en) | 1976-01-15 |
PL92423B1 (en) | 1977-04-30 |
JPS5653310B2 (en) | 1981-12-17 |
ZA73118B (en) | 1973-09-26 |
AU5087673A (en) | 1974-07-11 |
ES410490A1 (en) | 1975-12-01 |
CS181748B2 (en) | 1978-03-31 |
AU468083B2 (en) | 1975-12-18 |
YU184773A (en) | 1980-10-31 |
PL89131B1 (en) | 1976-10-30 |
FR2167217B1 (en) | 1975-06-13 |
ES410489A1 (en) | 1975-12-01 |
CS181717B2 (en) | 1978-03-31 |
JPS5622780A (en) | 1981-03-03 |
AR202800A1 (en) | 1975-07-24 |
SU488409A3 (en) | 1975-10-15 |
YU187473A (en) | 1980-10-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |