FR2132830B1 - - Google Patents

Info

Publication number
FR2132830B1
FR2132830B1 FR7212512A FR7212512A FR2132830B1 FR 2132830 B1 FR2132830 B1 FR 2132830B1 FR 7212512 A FR7212512 A FR 7212512A FR 7212512 A FR7212512 A FR 7212512A FR 2132830 B1 FR2132830 B1 FR 2132830B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7212512A
Other versions
FR2132830A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=5804433&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR2132830(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer AG filed Critical Bayer AG
Publication of FR2132830A1 publication Critical patent/FR2132830A1/fr
Application granted granted Critical
Publication of FR2132830B1 publication Critical patent/FR2132830B1/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00Compounds containing azido groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Coloring (AREA)
FR7212512A 1971-04-10 1972-04-10 Expired FR2132830B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2117571A DE2117571C3 (de) 1971-04-10 1971-04-10 Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel

Publications (2)

Publication Number Publication Date
FR2132830A1 FR2132830A1 (fr) 1972-11-24
FR2132830B1 true FR2132830B1 (fr) 1975-12-26

Family

ID=5804433

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7212512A Expired FR2132830B1 (fr) 1971-04-10 1972-04-10

Country Status (28)

Country Link
US (1) US3799934A (fr)
JP (1) JPS5529989B1 (fr)
AT (1) AT316551B (fr)
AU (1) AU464663B2 (fr)
BE (1) BE781878A (fr)
BG (1) BG22818A3 (fr)
CA (1) CA921035A (fr)
CH (1) CH567472A5 (fr)
CS (1) CS175429B2 (fr)
DD (2) DD99371A5 (fr)
DE (1) DE2117571C3 (fr)
DK (1) DK132496C (fr)
ES (1) ES401614A1 (fr)
FI (1) FI55186C (fr)
FR (1) FR2132830B1 (fr)
GB (1) GB1358951A (fr)
HK (1) HK18877A (fr)
HU (1) HU164705B (fr)
IE (1) IE36265B1 (fr)
IL (1) IL39171A (fr)
LU (1) LU65138A1 (fr)
NL (1) NL164031C (fr)
NO (1) NO135589C (fr)
PL (1) PL84499B1 (fr)
RO (2) RO62643A (fr)
SE (1) SE371823B (fr)
SU (1) SU435612A3 (fr)
ZA (1) ZA722348B (fr)

Families Citing this family (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4001258A (en) * 1972-03-06 1977-01-04 Bayer Aktiengesellschaft 2-amino-1,4-dihydropyridine derivatives
DE2210674C3 (de) * 1972-03-06 1981-09-24 Bayer Ag, 5090 Leverkusen 2-Amino-6-methyl-1,4-dihydropyridine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
US3917622A (en) * 1972-03-06 1975-11-04 Bayer Ag 2-Amino-1,4-dihydropyridine derivatives
US3917619A (en) * 1972-03-06 1975-11-04 Bayer Ag 2-Amino-4,5-dihydropyridine derivatives
US3935223A (en) * 1972-03-06 1976-01-27 Bayer Aktiengesellschaft 2-Amino-1,4-dihydropyridine derivatives
US3919246A (en) * 1972-03-06 1975-11-11 Bayer Ag Process for preparing 2-amino-1,4-dihydropyridine derivates
DD106832A5 (fr) * 1972-03-06 1974-07-05
DE2218644C3 (de) * 1972-04-18 1982-08-19 Bayer Ag, 5090 Leverkusen Basische Ester von 1,4-Dihydropyridinen, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2242786A1 (de) * 1972-08-31 1974-03-14 Bayer Ag Verfahren zur herstellung von neuen 2-amino-1,4-dihydropyridinen mit einer carbonylfunktion sowie ihre verwendung als arzneimittel
US3989708A (en) * 1972-08-31 1976-11-02 Bayer Aktiengesellschaft 2-Amino-1,4-dihydropyridine derivatives
DE2248150A1 (de) * 1972-09-30 1974-04-04 Bayer Ag Dihydropyridinpolyester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
GB1409865A (en) * 1973-02-13 1975-10-15 Science Union & Cie Dihydropyridines derivatives their preparation and pharmaceu tical compositions containing them
CH607848A5 (fr) * 1974-06-04 1978-11-30 Bayer Ag
DE2508181A1 (de) * 1975-02-26 1976-09-09 Bayer Ag 1,4-dihydropyridincarbonsaeurearal- kylester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
FR2320750A1 (fr) * 1975-08-12 1977-03-11 Hexachimie Dihydro-1,4 pyridines et leur application therapeutique
US4154839A (en) * 1975-11-05 1979-05-15 Bayer Aktiengesellschaft 2,6-Dimethyl-3-carboxymethoxy-4-(2-nitrophenyl)-5-carbisobutoxy-1,4-dihydropyridine
DE2549568C3 (de) * 1975-11-05 1981-10-29 Bayer Ag, 5090 Leverkusen 2,6-Dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl)-1,4-dihydropyridin-5- carbonsäureisobutylester, mehrere Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel
DE2650013C3 (de) * 1976-10-30 1981-04-02 Bayer Ag, 5090 Leverkusen 1.4-Dihydro-2.6-dimethyl-4-(3-nitrophenyl)-3.5-pyridindicarbonsäureisopropyl-(2-propoxy-äthyl)-ester, Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel
DE2658183A1 (de) * 1976-12-22 1978-07-06 Bayer Ag In 2-position substituierte 1,4- dihydropyridin-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
GB1579818A (en) * 1977-06-07 1980-11-26 Yamanouchi Pharma Co Ltd Nifedipine-containing solid preparation composition
JPS55301A (en) * 1978-02-14 1980-01-05 Yamanouchi Pharmaceut Co Ltd 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation
DE2815578C2 (de) * 1978-04-11 1986-01-16 Bayer Ag, 5090 Leverkusen Neue pharmazeutische Verwendung von Nimodipin
SE429652B (sv) * 1978-06-30 1983-09-19 Haessle Ab 2.6-dimetyl-4-(2.3-diklorfenyl)-1.4-dihydropyridin-3.5-dikarboxylsyra-3-metylester-5-etylester
DE2837477A1 (de) * 1978-08-28 1980-03-13 Bayer Ag Sila-substituierte 1,4-dihydropyridin- derivate
DE2841667A1 (de) * 1978-09-25 1980-04-10 Bayer Ag Fluorhaltige 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2949464A1 (de) * 1978-12-18 1980-06-26 Sandoz Ag Benzoxadiazole und benzothiadiazole, ihre herstellung und verwendung
DE2927933A1 (de) * 1979-07-11 1981-02-05 Hoechst Ag Acetylacetoxyalkyl-allyl-ether, ihre herstellung und verwendung
DE2935451A1 (de) * 1979-09-01 1981-03-19 Bayer Ag, 5090 Leverkusen Optisch aktive 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arneimittel
DE3023820A1 (de) * 1980-06-25 1982-01-14 Bayer Ag, 5090 Leverkusen 4,4-disubstituierte spiro-1,4-dihydropyridine, ein verfahren zu ihrer herstellung, sowie ihre verwendung als zwischenprodukt
DE3042769A1 (de) * 1980-11-13 1982-06-09 Bayer Ag, 5090 Leverkusen C-3 verknuepfte 1,4-dihydropyridine, ihre verwendung in arzneimitteln und verfahren zu ihrer herstellung
US4365063A (en) * 1981-08-31 1982-12-21 American Home Products Corporation Antihypertensive agents
US4321384A (en) * 1981-02-27 1982-03-23 American Home Products Corporation Antihypertensive agents
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
DE3130041A1 (de) * 1981-07-30 1983-02-17 Bayer Ag, 5090 Leverkusen Dihydropyridine mit positiv inotroper wirkung, neue verbindungen, ihre verwendung in arzneimitteln und verfahren zu ihrer herstellung
MX7567E (es) * 1981-12-23 1989-10-27 Yamanouchi Pharma Co Ltd Procedimiento para recubrir nicardipina de accion prolongada
JPS58159490A (ja) * 1982-02-23 1983-09-21 Nikken Kagaku Kk 1,4−ジヒドロピリジン化合物
DE3208628A1 (de) * 1982-03-10 1983-09-22 Bayer Ag, 5090 Leverkusen Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE3212736A1 (de) * 1982-04-06 1983-10-13 Bayer Ag, 5090 Leverkusen Verwendung von dihydropyridinen in arzneimitteln mit salidiuretischer wirkung
DE3222367A1 (de) * 1982-06-15 1983-12-15 Bayer Ag, 5090 Leverkusen Verwendung von 1,4-dihydropyridinen in antiarteriosklerotika und deren herstellung
US4656181A (en) * 1982-11-24 1987-04-07 Cermol S.A. Esters of 1,4-dihydropyridines, processes for the preparation of the new esters, and medicaments containing the same
DE3248548A1 (de) * 1982-12-29 1984-07-05 Heinrich Mack Nachf., 7918 Illertissen Acylderivate von 1,4:3,6-dianhydro-hexiten, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3316510A1 (de) * 1983-05-06 1984-11-08 Bayer Ag Parenterale formulierung von nimodipin, ein verfahren zu ihrer herstellung sowie ihre verwendung bei der bekaempfung von erkrankungen
GB8314744D0 (en) * 1983-05-27 1983-07-06 Fujisawa Pharmaceutical Co 2 6-disubstituted-1 4-dihydropyridine derivative
IE57810B1 (en) * 1984-03-27 1993-04-21 Delagrange Lab 1,4-dihydropyridine derivatives,their preparation and their use
DE3419128A1 (de) * 1984-05-23 1985-11-28 Bayer Ag, 5090 Leverkusen Dihydropyridinpraeparate und verfahren zu ihrer herstellung
US4794111A (en) * 1984-05-23 1988-12-27 Bayer Aktiengesellschaft Dihydropyridine preparations containing β-blockers
DE3419131A1 (de) * 1984-05-23 1985-11-28 Bayer Ag, 5090 Leverkusen Dihydropyridinkombinationspraeparate und verfahren zu ihrer herstellung
US4757071A (en) * 1984-12-14 1988-07-12 Nisshin Flour Milling Co., Ltd. 1,4-dihydropyridine derivatives, and pharmaceutical compositions containing same, useful for treating cardiovascular diseases
DE3542794A1 (de) * 1985-12-04 1987-06-11 Bayer Ag Antihypertensives kombinationspraeparat
US4771057A (en) * 1986-02-03 1988-09-13 University Of Alberta Reduced pyridyl derivatives with cardiovascular regulating properties
US4758669A (en) * 1986-05-05 1988-07-19 Radiation Oncology Center Research And Development Corporation 4-(nitrone aryl) dihydropyridines
EP0311053A3 (fr) * 1987-10-06 1991-05-08 Banyu Pharmaceutical Co., Ltd. Améliorateur de circulation cérébrale, isomère optique de NB-818, procédés pour sa production et son utilisation
DE3741540A1 (de) * 1987-12-08 1989-06-22 Bayer Ag Verfahren zur herstellung von unsymmetrischen dihydropyridinen
US5571827A (en) * 1990-03-13 1996-11-05 Sepracor Inc. Methods and compositions for treating hypertension, angina and other disorders using optically pure s(-) nitrendipine
DE4011105A1 (de) * 1990-04-06 1991-10-10 Bayer Ag Neue 4-chinolyl-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
US5204472A (en) * 1990-04-06 1993-04-20 Bayer Aktiengesellschaft Quinoline and isoquinoline intermediates
JPH0458703A (ja) * 1990-06-25 1992-02-25 Mitsubishi Electric Corp 引出形遮断器の導体固定装置
DE4134760A1 (de) * 1991-10-22 1993-07-08 Bayer Ag Aryl-chinolyl-substituierte 1,4-dihydropyridin-dicarbonsaeurederivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
US6735990B1 (en) * 1992-01-24 2004-05-18 Acco Brands, Inc. Computer physical security device
WO1994007476A1 (fr) * 1992-10-06 1994-04-14 Sepracor, Inc. Procedes et compositions permettant de traiter l'hypertenson, les angines et d'autres affections au moyen de nitredipine s(-) optiquement pure
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DE4236707A1 (de) * 1992-10-30 1994-05-05 Bayer Ag 4-Heterocyclyl substituierte Dihydropyridine
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ATE234286T1 (de) * 1993-12-10 2003-03-15 Bayer Ag Phenyl-substituierte 1,4-dihydropyridine mit cerebraler aktivität
TW483763B (en) * 1994-09-02 2002-04-21 Astra Ab Pharmaceutical composition comprising of ramipril and dihydropyridine compound
WO1997027177A2 (fr) * 1996-01-29 1997-07-31 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Derives de dihydropyridine-, pyridine-, benzopyrane- mono- et triazoloquinazoline, leur preparation, et utilsation comme antagonistes des recepteurs de l'adenosine
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DE1923990C3 (de) * 1969-05-10 1978-11-23 Bayer Ag Verfahren zur Herstellung von N-substituierten M-Dihydropyridin-S.S-dicarbonsäureestern

Also Published As

Publication number Publication date
FI55186C (fi) 1979-06-11
CS175429B2 (fr) 1977-05-31
ES401614A1 (es) 1975-11-01
FR2132830A1 (fr) 1972-11-24
LU65138A1 (fr) 1972-07-12
DK132496C (da) 1976-05-24
BE781878A (fr) 1972-10-10
IE36265L (en) 1972-10-10
DE2117571B2 (de) 1979-01-11
IL39171A (en) 1975-04-25
IL39171A0 (en) 1972-07-26
DE2117571A1 (de) 1972-10-19
RO62643A (fr) 1978-05-15
RO60479A (fr) 1976-08-15
GB1358951A (en) 1974-07-03
CA921035A (en) 1973-02-13
HK18877A (en) 1977-04-29
DE2117571C3 (de) 1979-10-11
DD99371A5 (fr) 1973-08-05
FI55186B (fi) 1979-02-28
DD102077A5 (fr) 1973-12-05
HU164705B (fr) 1974-04-11
NL164031B (nl) 1980-06-16
NL7204693A (fr) 1972-10-12
CH567472A5 (fr) 1975-10-15
NO135589C (fr) 1977-04-27
DK132496B (da) 1975-12-15
AU464663B2 (en) 1975-08-18
US3799934A (en) 1974-03-26
IE36265B1 (en) 1976-09-29
JPS5529989B1 (fr) 1980-08-07
AU4045572A (en) 1973-10-04
NO135589B (fr) 1977-01-17
SU435612A3 (ru) 1974-07-05
ZA722348B (en) 1972-12-27
BG22818A3 (fr) 1977-04-20
NL164031C (nl) 1980-11-17
AT316551B (de) 1974-07-25
PL84499B1 (fr) 1976-04-30
SE371823B (fr) 1974-12-02

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Legal Events

Date Code Title Description
CD Change of name or company name
CC Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990)

Free format text: 92C0036, 920310

CB Supplementary protection certificate (spc) granted (law of 25 june 1990)

Free format text: 92C0036, 720410

CP Supplementary protection certificate (spc) filed