FI962947A - Vesiliukoisia sientenvastaisia atsoleja - Google Patents

Vesiliukoisia sientenvastaisia atsoleja Download PDF

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Publication number
FI962947A
FI962947A FI962947A FI962947A FI962947A FI 962947 A FI962947 A FI 962947A FI 962947 A FI962947 A FI 962947A FI 962947 A FI962947 A FI 962947A FI 962947 A FI962947 A FI 962947A
Authority
FI
Finland
Prior art keywords
hydrogen
6alkyl
pct
image
insoles
Prior art date
Application number
FI962947A
Other languages
English (en)
Swedish (sv)
Other versions
FI962947A0 (fi
FI116057B (fi
Inventor
Jan Heeres
Leo Jacobus Jozef Backx
Der Eycken Luc Alfons Leo Van
Frank Christopher Odds
Jean Louis Mesens
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of FI962947A0 publication Critical patent/FI962947A0/fi
Publication of FI962947A publication Critical patent/FI962947A/fi
Application granted granted Critical
Publication of FI116057B publication Critical patent/FI116057B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
FI962947A 1994-01-24 1996-07-23 Vesiliukoisia sientenvastaisia atsoleja FI116057B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US18535294A 1994-01-24 1994-01-24
US18535294 1994-01-24
PCT/EP1995/000174 WO1995019983A1 (en) 1994-01-24 1995-01-17 Watersoluble azole antifungals
EP9500174 1995-01-17

Publications (3)

Publication Number Publication Date
FI962947A0 FI962947A0 (fi) 1996-07-23
FI962947A true FI962947A (fi) 1996-07-23
FI116057B FI116057B (fi) 2005-09-15

Family

ID=22680644

Family Applications (1)

Application Number Title Priority Date Filing Date
FI962947A FI116057B (fi) 1994-01-24 1996-07-23 Vesiliukoisia sientenvastaisia atsoleja

Country Status (31)

Country Link
US (1) US5707977A (fi)
EP (1) EP0741737B1 (fi)
JP (1) JP3764750B2 (fi)
KR (1) KR100352147B1 (fi)
CN (1) CN1078210C (fi)
AT (1) ATE186540T1 (fi)
AU (1) AU688455B2 (fi)
CA (1) CA2179640C (fi)
CY (1) CY2176B1 (fi)
CZ (1) CZ288544B6 (fi)
DE (1) DE69513279T2 (fi)
DK (1) DK0741737T3 (fi)
ES (1) ES2141329T3 (fi)
FI (1) FI116057B (fi)
GR (1) GR3032550T3 (fi)
HU (1) HU227281B1 (fi)
IL (1) IL112413A (fi)
LV (1) LV12634B (fi)
MY (1) MY111814A (fi)
NO (1) NO308412B1 (fi)
NZ (1) NZ278882A (fi)
PH (1) PH31664A (fi)
PL (1) PL181947B1 (fi)
PT (1) PT741737E (fi)
RU (1) RU2156764C2 (fi)
SG (1) SG48386A1 (fi)
SI (1) SI0741737T1 (fi)
SK (1) SK282059B6 (fi)
TW (1) TW376385B (fi)
WO (1) WO1995019983A1 (fi)
ZA (1) ZA95521B (fi)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW457240B (en) * 1995-04-20 2001-10-01 Janssen Pharmaceutica Nv Novel triazolones as apolipoprotein-B synthesis inhibitors
IL118464A (en) * 1995-06-02 2000-08-13 Schering Corp (2R-cis)-4-¬4-¬4-¬4¬¬-5-(2',4 dihalophenyl)-tetrahydro-5-(1-H-1,2,4,triazol-1-yl-methyl)furan-3-yl(methoxy¾phenyl¾-1-piperazinyl¬phenyl2,4,dihydro2¬(5)-1-ethyl-2-(5)hydroxy propyl¾-3H-1,2,4-triazol-3-one and pharmaceutical compositions comprising them
ATE247108T1 (de) * 1995-06-19 2003-08-15 Schering Corp Antifungale tetrahydrofurane
US5698557A (en) * 1995-06-19 1997-12-16 Schering Corporation Hydroxy-substituted antifungals
GB9602080D0 (en) * 1996-02-02 1996-04-03 Pfizer Ltd Pharmaceutical compounds
NZ328607A (en) * 1996-09-09 1999-08-30 Hoffmann La Roche Heterocyclically substituted n-benzyl-azolium derivatives and fungicidal compositions
AU5251298A (en) * 1996-11-12 1998-06-03 Sepracor, Inc. (2r,4s,s,r-) and (2s,4r,s,r-)hydroxyitraconazole
EP0938484A1 (en) * 1996-11-12 1999-09-01 Sepracor, Inc. 2r,4s,r,r- and 2s,4r,r,r-hydroxyitraconazole
CN1237172A (zh) * 1996-11-12 1999-12-01 塞普拉科公司 2r,4s,r,s－和2s,4r,r,s－羟基伊曲康唑－和羟基沙波康唑衍生物
AU5432698A (en) 1996-11-12 1998-06-03 Sepracor, Inc. 2r,4s,s,s- and 2s,4r,s,s-hydroxyitraconazole
KR100509171B1 (ko) 1997-02-11 2005-08-22 얀센 파마슈티카 엔.브이. 아미노산 에스테르를 포함하는 아졸 항진균제
JP4473350B2 (ja) * 1997-07-11 2010-06-02 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ２，４，４−三置換−１，３−ジオキソラン抗菌・抗カビ剤
TW593312B (en) * 1997-07-11 2004-06-21 Janssen Pharmaceutica Nv 2,4,4-trisubstituted-1,3-dioxolane antifungals
ATE263163T1 (de) * 1997-10-07 2004-04-15 Schering Corp Krytallinischer fungizider polymorph
EP0957101A1 (en) * 1998-05-14 1999-11-17 Janssen Pharmaceutica N.V. Water soluble azoles as broad-spectrum antifungals
US6265584B1 (en) * 1998-05-22 2001-07-24 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
WO2000030655A1 (en) 1998-11-20 2000-06-02 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
US6362172B2 (en) 2000-01-20 2002-03-26 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
US6448401B1 (en) * 2000-11-20 2002-09-10 Bristol-Myers Squibb Company Process for water soluble azole compounds
AR052342A1 (es) * 2004-12-21 2007-03-14 Janssen Pharmaceutica Nv Derivados sustituidos de triazolona,tetrazolona e imidazolona con actividad selectiva antagonista de alfa2c-adenoreceptores
JO2691B1 (en) * 2005-05-03 2013-03-03 ايساي آر آند دي مانجمنت كو.، ليمتد Monolysine salts for azole compounds
JP2012502028A (ja) * 2008-09-08 2012-01-26 ウ，ニアン トリアゾール抗真菌剤
RU2563811C1 (ru) * 2014-08-08 2015-09-20 Федеральное государственное бюджетное учреждение науки Институт химической физики им. Н.Н. Семенова Российской академии наук (ИХФ РАН) Фармацевтическая композиция для лечения грибковых заболеваний
CN106243087B (zh) * 2016-09-12 2018-10-09 三峡大学 一种***吡咯烷酮类杀菌剂，合成方法及其应用
CN111138421A (zh) * 2019-12-26 2020-05-12 上海英诺富成生物科技有限公司 抗真菌水溶性化合物及其制备方法与应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4218458A (en) * 1978-06-23 1980-08-19 Janssen Pharmaceutica, N.V. Heterocyclic derivatives of (4-aryloxy-methyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles
CA1292472C (en) * 1985-12-03 1991-11-26 Alfonsus Guilielmus Knaeps Derivatives of ¬¬4-¬4-(4-phenyl-1-piperazinyl)- phenoxymethyl|-1,3-dioxolan-2-yl|methyl|-1h-imidazoles and 1h-1,2,4-triazoles
US4791111A (en) * 1985-12-23 1988-12-13 Janssen Pharmaceutica, N.V. [[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles having anti-microbial properties
NZ223799A (en) * 1987-03-25 1989-12-21 Janssen Pharmaceutica Nv Azolylmethyl-dioxolanylmethoxyphenyl-piperazinyl-phenyl-triazolones and antimicrobial compositions
US5039676A (en) * 1990-05-11 1991-08-13 Schering Corporation Tri- and tetra-substituted-oxetanes and tetrahydrofurans and intermediates thereof
IL103558A0 (en) * 1991-10-30 1993-03-15 Schering Corp Tri-substituted tetrahydrofuran antifungals
CN1064685C (zh) * 1993-12-21 2001-04-18 先灵公司 四氢呋喃抗真菌剂

Also Published As

Publication number Publication date
NO308412B1 (no) 2000-09-11
EP0741737B1 (en) 1999-11-10
TW376385B (en) 1999-12-11
RU2156764C2 (ru) 2000-09-27
IL112413A0 (en) 1995-03-30
AU688455B2 (en) 1998-03-12
PL181947B1 (en) 2001-10-31
IL112413A (en) 1999-11-30
LV12634A (lv) 2001-03-20
NO963073L (no) 1996-07-23
CA2179640A1 (en) 1995-07-27
KR100352147B1 (ko) 2002-11-11
EP0741737A1 (en) 1996-11-13
SK282059B6 (sk) 2001-10-08
ZA95521B (en) 1996-07-23
PL315558A1 (en) 1996-11-12
LV12634B (en) 2001-07-20
JPH09508360A (ja) 1997-08-26
US5707977A (en) 1998-01-13
FI962947A0 (fi) 1996-07-23
ATE186540T1 (de) 1999-11-15
PT741737E (pt) 2000-04-28
NZ278882A (en) 1997-06-24
FI116057B (fi) 2005-09-15
PH31664A (en) 1999-01-12
HUT75943A (en) 1997-05-28
GR3032550T3 (en) 2000-05-31
AU1535595A (en) 1995-08-08
CY2176B1 (en) 2002-08-23
MY111814A (en) 2001-01-31
NO963073D0 (no) 1996-07-23
ES2141329T3 (es) 2000-03-16
DE69513279T2 (de) 2000-07-13
DK0741737T3 (da) 2000-05-22
HU227281B1 (en) 2011-01-28
JP3764750B2 (ja) 2006-04-12
CN1138862A (zh) 1996-12-25
CN1078210C (zh) 2002-01-23
DE69513279D1 (de) 1999-12-16
CA2179640C (en) 2005-11-15
SI0741737T1 (en) 2000-02-29
WO1995019983A1 (en) 1995-07-27
CZ195696A3 (en) 1997-02-12
SK89696A3 (en) 1998-02-04
HU9602008D0 (en) 1996-09-30
CZ288544B6 (cs) 2001-07-11
SG48386A1 (en) 1998-04-17

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