FI961914A0 - Lyhytvaikutteiset dihydropyridiinit - Google Patents

Lyhytvaikutteiset dihydropyridiinit

Info

Publication number: FI961914A0
Authority: FI; Finland
Prior art keywords: hydrogen; pct; chloro; methyl; nitro
Prior art date: 1993-11-05

Application number

FI961914A

Other languages

English (en)

Swedish (sv)

Other versions

FI110429B (fi

FI961914A (fi

Inventor

Kjell Hjalmar Andersson

Margareta Nordlander

Rolf Christer Westerlund

Original Assignee

Astra Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-11-05

Filing date

1996-05-06

Publication date

1996-05-06

1996-05-06 Application filed by Astra Ab filed Critical Astra Ab

1996-05-06 Publication of FI961914A0 publication Critical patent/FI961914A0/fi

1996-05-06 Publication of FI961914A publication Critical patent/FI961914A/fi

2003-01-31 Application granted granted Critical

2003-01-31 Publication of FI110429B publication Critical patent/FI110429B/fi

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

FI961914A 1993-11-05 1996-05-06 Menetelmä farmaseuttisten dihydropyridiinien valmistamiseksi FI110429B (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
SE9303657A SE9303657D0 (sv)	1993-11-05	1993-11-05	Short-acting dihydropyridines
SE9303657		1993-11-05
SE9401031		1994-11-03
PCT/SE1994/001031 WO1995012578A1 (en)	1993-11-05	1994-11-03	Short-acting dihydropyridines

Publications (3)

Publication Number	Publication Date
FI961914A0 true FI961914A0 (fi)	1996-05-06
FI961914A FI961914A (fi)	1996-05-06
FI110429B FI110429B (fi)	2003-01-31

Family

ID=20391655

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI961914A FI110429B (fi)	1993-11-05	1996-05-06	Menetelmä farmaseuttisten dihydropyridiinien valmistamiseksi

Country Status (36)

Country	Link
US (1)	US5856346A (fi)
EP (1)	EP0726894B1 (fi)
JP (1)	JP3712209B2 (fi)
KR (1)	KR100331663B1 (fi)
CN (1)	CN1049428C (fi)
AT (1)	ATE194330T1 (fi)
AU (1)	AU685532B2 (fi)
BR (1)	BR9407946A (fi)
CA (1)	CA2174969C (fi)
CZ (1)	CZ285691B6 (fi)
DE (1)	DE69425152T2 (fi)
DK (1)	DK0726894T3 (fi)
EE (1)	EE03230B1 (fi)
EG (1)	EG20539A (fi)
ES (1)	ES2150544T3 (fi)
FI (1)	FI110429B (fi)
FR (1)	FR12C0053I2 (fi)
GR (1)	GR3034469T3 (fi)
HK (1)	HK1013292A1 (fi)
HU (1)	HU215591B (fi)
IL (1)	IL111127A (fi)
IS (1)	IS1674B (fi)
LU (1)	LU92209I2 (fi)
MY (1)	MY111770A (fi)
NO (1)	NO305656B1 (fi)
NZ (1)	NZ275915A (fi)
PL (1)	PL185099B1 (fi)
PT (1)	PT726894E (fi)
RU (1)	RU2139278C1 (fi)
SA (1)	SA94150250B1 (fi)
SE (1)	SE9303657D0 (fi)
SK (1)	SK281467B6 (fi)
TW (1)	TW279859B (fi)
UA (1)	UA45959C2 (fi)
WO (1)	WO1995012578A1 (fi)
ZA (1)	ZA947570B (fi)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE9804002D0 (sv) *	1998-11-23	1998-11-23	Astra Ab	New manufacturing process
WO2003059193A2 (en) *	2001-12-21	2003-07-24	Alcon, Inc.	Use of nanoparticles as carriers for biocides in ophthalmic compositions
FR2922439B1 (fr) *	2007-10-18	2010-12-10	Hill Rom Ind Sa	Procede de gonflage alterne d'un dispositif de support a cellules gonflables et dispositif pour sa mise en oeuvre
AU2009276560B2 (en)	2008-08-01	2015-04-16	Chiesi Farmaceutici S.P.A.	Pharmaceutical compositions and methods for producing low impurity concentrations of the same
EP2482658B1 (en) *	2009-09-30	2015-07-01	MicroDose Therapeutx, Inc.	Methods and compositions for treatment of raynaud's phenomenon
CN101780036B (zh) *	2010-03-30	2011-11-16	武汉武药科技有限公司	丁酸氯维地平脂微球注射液及其制备方法
CA2701087A1 (en) *	2010-04-12	2011-10-12	Alphora Research Inc.	Preparation of clevidipine butyrate ring the same
US8455655B2 (en)	2010-05-07	2013-06-04	Laboratorios Lesvi, S.L.	Preparation of dihydropyridines
EP3020704A3 (en)	2010-05-07	2016-11-09	Laboratorios Lesvi, S.L.	Crystalline polymorphs of clevidipine butyrate
AU2011313852B2 (en)	2010-10-12	2015-07-02	Chiesi Farmaceutici S.P.A.	Clevidipine emulsion formulations containing antimicrobial agents
US8658676B2 (en)	2010-10-12	2014-02-25	The Medicines Company	Clevidipine emulsion formulations containing antimicrobial agents
RU2623039C2 (ru) *	2011-04-01	2017-06-21	КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А.	Дигидропиридины (клевидипин) кратковременного действия для применения в восстановлении после инсульта
WO2013030725A1 (en)	2011-08-26	2013-03-07	Wockhardt Limited	Methods for treating cardiovascular disorders
CN103420899B (zh) *	2012-05-25	2016-01-27	四川科伦药物研究有限公司	一种丁酸氯维地平的纯化方法
JP6329957B2 (ja)	2012-10-26	2018-05-23	キエージィファーマチェウティチエス．ペー．アー．	心不全において血圧を制御するためおよび呼吸困難を低減させるための方法
CN103073485B (zh) *	2013-01-17	2015-09-02	北京嘉林药业股份有限公司	一种丁酸氯维地平的制备方法
CN103086956B (zh) *	2013-01-17	2015-11-04	北京嘉林药业股份有限公司	一种丁酸氯维地平中间体的纯化方法
RU2759673C2 (ru)	2014-05-19	2021-11-16	КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А.	Наночастицы клевидипина и их фармацевтические композиции
CN105367487A (zh) *	2014-08-23	2016-03-02	南京海纳医药科技有限公司	一种丁酸氯维地平重要中间体新的合成方法
CN104370802A (zh) *	2014-09-24	2015-02-25	北京蓝丹医药科技有限公司	氯维地平衍生物及其制备方法
SG10202103403SA (en)	2015-05-20	2021-05-28	Boehringer Ingelheim Animal Health Usa Inc	Anthelmintic depsipeptide compounds
CN108699052B (zh)	2015-12-28	2022-04-29	勃林格殷格翰动物保健美国公司	驱虫缩酚酸肽化合物
CA3044038A1 (en)	2016-11-16	2018-05-24	Boehringer Ingelheim Animal Health USA Inc.	Anthelmintic depsipeptide compounds
RU2755349C1 (ru) *	2021-02-16	2021-09-15	Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ")	Применение бензил 6-({ 2-[(3,4-диметилфенил)амино]-2-оксоэтил} тио)-2-метил-4-(4-хлорфенил)-5-циано-1,4-дигидропиридин-3-карбоксилата в качестве гепатопротекторного средства

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2117571C3 (de) *	1971-04-10	1979-10-11	Bayer Ag, 5090 Leverkusen	Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
US4154839A (en) *	1975-11-05	1979-05-15	Bayer Aktiengesellschaft	2,6-Dimethyl-3-carboxymethoxy-4-(2-nitrophenyl)-5-carbisobutoxy-1,4-dihydropyridine
DE2847236A1 (de) *	1978-10-31	1980-05-14	Bayer Ag	Neue dihydropyridine mit substituierten estergruppierungen, mehrer verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
KR940003492B1 (ko) *	1988-10-27	1994-04-23	주식회사 유한양행	1,4-디하이드로피리딘유도체 및 그의 제조방법
US5134139A (en) *	1989-08-31	1992-07-28	Tanabe Seiyaku Co., Ltd.	1,5-benzothiazepine derivatives and preparation thereof
JPH0641075A (ja) *	1990-09-01	1994-02-15	Kazuo Achinami	新規な１，４−ジヒドロピリジン化合物及びその製造方法

1993
- 1993-11-05 SE SE9303657A patent/SE9303657D0/xx unknown
1994
- 1994-09-28 ZA ZA947570A patent/ZA947570B/xx unknown
- 1994-09-29 TW TW083108995A patent/TW279859B/zh not_active IP Right Cessation
- 1994-09-30 IS IS4218A patent/IS1674B/is unknown
- 1994-10-03 IL IL11112794A patent/IL111127A/xx not_active IP Right Cessation
- 1994-10-19 SA SA94150250A patent/SA94150250B1/ar unknown
- 1994-11-02 EG EG68994A patent/EG20539A/xx active
- 1994-11-03 EE EE9600051A patent/EE03230B1/xx unknown
- 1994-11-03 JP JP51317095A patent/JP3712209B2/ja not_active Expired - Lifetime
- 1994-11-03 UA UA96041753A patent/UA45959C2/uk unknown
- 1994-11-03 PT PT95900347T patent/PT726894E/pt unknown
- 1994-11-03 CZ CZ961273A patent/CZ285691B6/cs not_active IP Right Cessation
- 1994-11-03 NZ NZ275915A patent/NZ275915A/en not_active IP Right Cessation
- 1994-11-03 ES ES95900347T patent/ES2150544T3/es not_active Expired - Lifetime
- 1994-11-03 SK SK559-96A patent/SK281467B6/sk not_active IP Right Cessation
- 1994-11-03 AT AT95900347T patent/ATE194330T1/de active
- 1994-11-03 DE DE69425152T patent/DE69425152T2/de not_active Expired - Lifetime
- 1994-11-03 CA CA002174969A patent/CA2174969C/en not_active Expired - Lifetime
- 1994-11-03 US US08/356,224 patent/US5856346A/en not_active Expired - Lifetime
- 1994-11-03 HU HU9601187A patent/HU215591B/hu unknown
- 1994-11-03 BR BR9407946A patent/BR9407946A/pt not_active Application Discontinuation
- 1994-11-03 KR KR1019960702346A patent/KR100331663B1/ko not_active IP Right Cessation
- 1994-11-03 WO PCT/SE1994/001031 patent/WO1995012578A1/en active IP Right Grant
- 1994-11-03 CN CN94194500A patent/CN1049428C/zh not_active Expired - Lifetime
- 1994-11-03 DK DK95900347T patent/DK0726894T3/da active
- 1994-11-03 AU AU81196/94A patent/AU685532B2/en not_active Expired
- 1994-11-03 PL PL94314128A patent/PL185099B1/pl unknown
- 1994-11-03 EP EP95900347A patent/EP0726894B1/en not_active Expired - Lifetime
- 1994-11-03 RU RU96112152A patent/RU2139278C1/ru active
- 1994-11-04 MY MYPI94002934A patent/MY111770A/en unknown
1996
- 1996-05-02 NO NO961776A patent/NO305656B1/no not_active IP Right Cessation
- 1996-05-06 FI FI961914A patent/FI110429B/fi not_active IP Right Cessation
1998
- 1998-12-22 HK HK98114638A patent/HK1013292A1/xx unknown
2000
- 2000-09-21 GR GR20000402158T patent/GR3034469T3/el unknown
2012
- 2012-09-18 FR FR12C0053C patent/FR12C0053I2/fr active Active
2013
- 2013-06-10 LU LU92209C patent/LU92209I2/fr unknown

Also Published As

Publication number	Publication date
DE69425152D1 (de)	2000-08-10
NZ275915A (en)	1997-04-24
HU9601187D0 (en)	1996-07-29
DK0726894T3 (da)	2000-10-23
NO961776D0 (no)	1996-05-02
SK55996A3 (en)	1996-12-04
JPH09504542A (ja)	1997-05-06
SK281467B6 (sk)	2001-04-09
EG20539A (en)	1999-07-31
NO961776L (no)	1996-05-02
MY111770A (en)	2000-12-30
CN1049428C (zh)	2000-02-16
CN1137269A (zh)	1996-12-04
UA45959C2 (uk)	2002-05-15
RU2139278C1 (ru)	1999-10-10
GR3034469T3 (en)	2000-12-29
FI110429B (fi)	2003-01-31
CZ127396A3 (en)	1996-09-11
PL185099B1 (pl)	2003-02-28
EP0726894A1 (en)	1996-08-21
ATE194330T1 (de)	2000-07-15
LU92209I2 (fr)	2013-08-23
PL314128A1 (en)	1996-08-19
CZ285691B6 (cs)	1999-10-13
JP3712209B2 (ja)	2005-11-02
SA94150250B1 (ar)	2006-03-01
KR100331663B1 (ko)	2002-09-26
AU685532B2 (en)	1998-01-22
US5856346A (en)	1999-01-05
HK1013292A1 (en)	1999-08-20
BR9407946A (pt)	1996-11-26
ES2150544T3 (es)	2000-12-01
IS4218A (is)	1995-05-06
EE03230B1 (et)	1999-10-15
TW279859B (fi)	1996-07-01
CA2174969C (en)	2005-05-17
PT726894E (pt)	2000-10-31
CA2174969A1 (en)	1995-05-11
HUT75316A (en)	1997-05-28
ZA947570B (en)	1995-05-29
HU215591B (hu)	1999-01-28
IL111127A0 (en)	1994-12-29
FI961914A (fi)	1996-05-06
FR12C0053I1 (fi)	2012-02-11
IL111127A (en)	2000-11-21
IS1674B (is)	1997-12-31
FR12C0053I2 (fr)	2013-08-16
NO305656B1 (no)	1999-07-05
DE69425152T2 (de)	2001-03-22
WO1995012578A1 (en)	1995-05-11
EP0726894B1 (en)	2000-07-05
SE9303657D0 (sv)	1993-11-05
AU8119694A (en)	1995-05-23

Legal Events

Date

Code

Title

Description

2008-11-26

PC

Transfer of assignment of patent

Owner name: ASTRAZENECA AB

Free format text: ASTRAZENECA AB

2014-12-18

MA

Patent expired

Publication	Publication Date	Title
FI961914A0 (fi)	1996-05-06	Lyhytvaikutteiset dihydropyridiinit
ES8401460A1 (es)	1983-12-01	Un procedimiento para preparar derivados de benzamida.
NO923413D0 (no)	1992-09-01	Terapeutiske benzazepin-forbindelser
IL108970A0 (en)	1994-06-24	Substituted (arylalkylaminobenzyl) aminopropionamide derivatives, their preparation and pharmaceutical compositions containing them