FI951535A0 - Immunogeeninen meningokokki -LPS ja siitä saadut ulkomembraanirakkulat ja rokote - Google Patents

Immunogeeninen meningokokki -LPS ja siitä saadut ulkomembraanirakkulat ja rokote

Info

Publication number
FI951535A0
FI951535A0 FI951535A FI951535A FI951535A0 FI 951535 A0 FI951535 A0 FI 951535A0 FI 951535 A FI951535 A FI 951535A FI 951535 A FI951535 A FI 951535A FI 951535 A0 FI951535 A0 FI 951535A0
Authority
FI
Finland
Prior art keywords
outer membrane
omp
pct
lipopolysaccharide
directed
Prior art date
Application number
FI951535A
Other languages
English (en)
Swedish (sv)
Other versions
FI951535A (fi
Inventor
Der Ley Peter Andre Van
Jan Theunis Poolman
Peter Hoogerhout
Original Assignee
Nederlanden Staat
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nederlanden Staat filed Critical Nederlanden Staat
Publication of FI951535A0 publication Critical patent/FI951535A0/fi
Publication of FI951535A publication Critical patent/FI951535A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FI951535A 1992-10-02 1995-03-31 Immunogeeninen meningokokki -LPS ja siitä saadut ulkomembraanirakkulat ja rokote FI951535A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL9201716A NL9201716A (nl) 1992-10-02 1992-10-02 Buitenmembraanvesikel dat voorzien is van een groep polypeptiden welke ten minste de immuunwerking van aan membraan gebonden buitenmembraaneiwitten (OMP's) hebben, werkwijze ter bereiding ervan alsmede een vaccin dat een dergelijk buitenmembraanvesikel omvat.
PCT/NL1993/000163 WO1994008021A1 (en) 1992-10-02 1993-07-30 Immunogenic meningococcal lps and outer membrane vesicles and vaccine therefrom

Publications (2)

Publication Number Publication Date
FI951535A0 true FI951535A0 (fi) 1995-03-31
FI951535A FI951535A (fi) 1995-06-01

Family

ID=19861338

Family Applications (1)

Application Number Title Priority Date Filing Date
FI951535A FI951535A (fi) 1992-10-02 1995-03-31 Immunogeeninen meningokokki -LPS ja siitä saadut ulkomembraanirakkulat ja rokote

Country Status (14)

Country Link
US (1) US5705161A (fi)
EP (1) EP0680512B1 (fi)
JP (1) JPH08501940A (fi)
AT (1) ATE364702T1 (fi)
AU (1) AU684720B2 (fi)
CA (1) CA2146145C (fi)
DE (1) DE69334147T2 (fi)
DK (1) DK0680512T3 (fi)
ES (1) ES2289739T3 (fi)
FI (1) FI951535A (fi)
NL (1) NL9201716A (fi)
NO (1) NO321651B1 (fi)
PT (1) PT680512E (fi)
WO (1) WO1994008021A1 (fi)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7118757B1 (en) * 1988-12-19 2006-10-10 Wyeth Holdings Corporation Meningococcal class 1 outer-membrane protein vaccine
CA2182637A1 (en) * 1995-08-04 1997-02-05 Jagath L. Kadurugamuwa Novel vaccines and pharmaceutical compositions using membrane vesicles of microorganisms, and methods for preparing them
US20020028215A1 (en) 1999-08-09 2002-03-07 Jagath L. Kadurugamuwa Novel vaccines and pharmaceutical compositions using membrane vesicles of microorganisms, and methods for preparing same
US6872398B2 (en) * 1995-12-22 2005-03-29 The United States Of America As Represented By The Secretary Of The Army Conjugate vaccine against gram-negative bacterial infections
US6645503B1 (en) * 1998-03-10 2003-11-11 Wyeth Holdings Corporation Antigenic conjugates of conserved lipopolysaccharides of gram negative bacteria
US10967045B2 (en) 1998-11-02 2021-04-06 Secretary of State for Health and Social Care Multicomponent meningococcal vaccine
GB9823978D0 (en) * 1998-11-02 1998-12-30 Microbiological Res Authority Multicomponent meningococcal vaccine
US6514948B1 (en) * 1999-07-02 2003-02-04 The Regents Of The University Of California Method for enhancing an immune response
US6531131B1 (en) 1999-08-10 2003-03-11 The United States Of America As Represented By The Department Of Health And Human Services Conjugate vaccine for Neisseria meningitidis
DE60042489D1 (de) 1999-09-30 2009-08-13 Isis Innovation Impfstoff gegen neisseria infektion
KR20030024811A (ko) * 2000-07-27 2003-03-26 칠드런즈 하스피틀 앤드 리써치 센터 앳 오클랜드 나이세리아 메닌지티디스에 의하여 유발되는 질병에 대한광범위하게 유효한 보호를 위한 백신
EP1495039A4 (en) * 2002-03-20 2006-07-26 Univ Emory MUTANTS OF NEISSERIA, LIPOOLIGOSACCHARIDES AND IMMUNOGENIC COMPOSITIONS
KR101140033B1 (ko) 2002-08-02 2012-05-07 글락소스미스클라인 바이오로지칼즈 에스.에이. 항원 조합물을 포함하는 나이세리아 백신 조성물
GB0220194D0 (en) 2002-08-30 2002-10-09 Chiron Spa Improved vesicles
DE60335477D1 (de) 2002-10-11 2011-02-03 Novartis Vaccines & Diagnostic Polypeptidimpstoffe zum breiten schutz gegen hypervirulente meningokokken-linien
CA2506318C (en) 2002-11-15 2011-07-12 Chiron Srl Unexpected surface proteins in neisseria meningitidis
GB0227346D0 (en) 2002-11-22 2002-12-31 Chiron Spa 741
CN102302776B (zh) 2003-01-30 2014-06-18 诺华疫苗和诊断有限公司 抗多种脑膜炎球菌血清组的可注射性疫苗
GB0323103D0 (en) 2003-10-02 2003-11-05 Chiron Srl De-acetylated saccharides
GB0408977D0 (en) 2004-04-22 2004-05-26 Chiron Srl Immunising against meningococcal serogroup Y using proteins
US7537766B2 (en) * 2004-08-30 2009-05-26 Wyeth Neisseria meningitidis inner core lipo-oligosaccharide epitopes, multivalent conjugates thereof and immunogenic compositions thereof
GB0424092D0 (en) 2004-10-29 2004-12-01 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
EP1855715B1 (en) 2005-01-27 2013-03-13 Children's Hospital & Research Center at Oakland Gna1870-based vesicle vaccines for broad spectrum protection against diseases caused by neisseria meningitidis
GB0524066D0 (en) 2005-11-25 2006-01-04 Chiron Srl 741 ii
ES2337309T5 (es) 2006-06-12 2013-07-30 Glaxosmithkline Biologicals S.A. Vacuna
EP2245048B1 (en) 2008-02-21 2014-12-31 Novartis AG Meningococcal fhbp polypeptides
RU2477145C2 (ru) * 2008-05-30 2013-03-10 ДЗЕ Ю.Эс.Эй., ЭС РЕПРЕЗЕНТЕД БАЙ ДЗЕ СЕКРЕТАРИ ОФ ДЗЕ АРМИ, ОН БЕХАФ ОФ УОЛТЕР РИД АРМИ Мультивалентная вакцина из нативных везикул наружной мембраны менингококков, способы ее получения и применения
JP5668049B2 (ja) 2009-03-24 2015-02-12 ノバルティス アーゲー 髄膜炎菌ｈ因子結合タンパク質および肺炎球菌糖結合体の組み合わせ
EP2411048B1 (en) 2009-03-24 2020-05-06 GlaxoSmithKline Biologicals SA Adjuvanting meningococcal factor h binding protein
DK2430151T3 (da) * 2009-05-14 2014-09-15 Sanofi Pasteur Meningokokvaccine på basis af lipooligosaccharid (los) fra modificerede stammer af neisseria meningitidis med immuntype l6
WO2010134225A1 (ja) * 2009-05-20 2010-11-25 国立大学法人鳥取大学 部分糖鎖エピトープを用いた、病原性ナイセリア属細菌感染の検出方法およびそれら細菌に対するワクチン
NZ598459A (en) 2009-08-27 2014-03-28 Novartis Ag Adjuvant comprising aluminium, oligonucleotide and polycation
CN102596240B (zh) 2009-08-27 2015-02-04 诺华股份有限公司 包括脑膜炎球菌fHBP序列的杂交多肽
EP2483390A2 (en) 2009-09-30 2012-08-08 Novartis AG Expression of meningococcal fhbp polypeptides
AU2010310985B2 (en) 2009-10-27 2014-11-06 Glaxosmithkline Biologicals S.A. Modified meningococcal fHBP polypeptides
MX2012010609A (es) 2010-03-18 2012-10-03 Novartis Ag Vacunas adyuvadas para meningococos serogrupo b.
WO2011161653A1 (en) 2010-06-25 2011-12-29 Novartis Ag Combinations of meningococcal factor h binding proteins
BR112014016223A8 (pt) 2011-12-29 2017-07-04 Novartis Ag combinações adjuvantes de proteínas de ligação de fator h meningocócico
SG10201907875TA (en) 2014-02-28 2019-09-27 Glaxosmithkline Biologicals Sa Modified meningococcal fhbp polypeptides
GB201712824D0 (en) 2017-08-10 2017-09-27 Glaxosmithkline Biologicals Sa Multi-functionalized nOMV Conjugates
EP3836957A1 (en) * 2018-08-14 2021-06-23 Evercyte GmbH Target-specific extracellular vesicles
AU2022208435A1 (en) 2021-01-18 2023-08-10 Conserv Bioscience Limited Coronavirus immunogenic compositions, methods and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU640118B2 (en) * 1988-12-19 1993-08-19 De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezonheid En Cultuur Meningococcal class 1 outer-membrane protein vaccine
NL9101359A (nl) * 1991-08-07 1993-03-01 Nederlanden Staat Nieuw saccharide-peptide-conjugaat, werkwijze ter bereiding ervan alsmede een vaccin dat een dergelijk saccharide-peptide-conjugaat omvat.

Also Published As

Publication number Publication date
NO951181D0 (no) 1995-03-28
NO951181L (no) 1995-06-01
NL9201716A (nl) 1994-05-02
DK0680512T3 (da) 2007-10-01
EP0680512A1 (en) 1995-11-08
WO1994008021A1 (en) 1994-04-14
ATE364702T1 (de) 2007-07-15
AU4835193A (en) 1994-04-26
AU684720B2 (en) 1998-01-08
NO321651B1 (no) 2006-06-19
CA2146145C (en) 2009-10-27
JPH08501940A (ja) 1996-03-05
FI951535A (fi) 1995-06-01
DE69334147D1 (de) 2007-07-26
DE69334147T2 (de) 2008-02-14
ES2289739T3 (es) 2008-02-01
EP0680512B1 (en) 2007-06-13
PT680512E (pt) 2007-09-25
US5705161A (en) 1998-01-06
CA2146145A1 (en) 1994-04-14

Similar Documents

Publication Publication Date Title
FI951535A0 (fi) Immunogeeninen meningokokki -LPS ja siitä saadut ulkomembraanirakkulat ja rokote
WO1990006696A3 (en) Meningococcal class 1 outer-membrane protein vaccine
NO943739L (no) Vaksiner inneholdende vesikler basert på ikke-ioniske overflate-aktive midler
Lowell et al. Peptides bound to proteosomes via hydrophobic feet become highly immunogenic without adjuvants.
Wetzler et al. Gonococcal porin vaccine evaluation: comparison of Por proteosomes, liposomes, and blebs isolated from rmp deletion mutants
AU657487B2 (en) Nucleotide sequence coding for an outer membrane protein from neisseria meningitidis and use of said protein in vaccine preparations
Dale et al. Type-specific immunogenicity of a chemically synthesized peptide fragment of type 5 streptococcal M protein.
ES2063965T3 (es) Vacunas para haemophilus influenzae no tipificable.
Livingston et al. GD3/proteosome vaccines induce consistent IgM antibodies against the ganglioside GD3
Muttilainen et al. TheNeisseria meningitidisouter membrane protein P1 produced inBacillus subtilisand reconstituted into phospholipid vesicles elicits antibodies to native P1 epitopes
FI924457A0 (fi) Kompositioner och behandlingsfoerfarande foer lunginflammation i djur
DE68915046D1 (de) Haemophilus influenzae Typ B Polysaccharid-Aussermembranprotein-Konjugat als Impfstoff.
Livingston et al. The serologic response to Meth A sarcoma vaccines after cyclophosphamide treatment is additionally increased by various adjuvants.
CA2007248A1 (en) Meningococcal class 1 outer-membrane protein vaccine
Van Welzijn Jay R. Luly; Megumi Kawai; Or Yat Sun; Paul Wiedeman; Rolf Wagner Abbott Laboratories, Libertyville, IL, United States
KR980009453A (ko) B형 간염 바이러스의 x 단백질 유래의 펩타이드 항원을 함유하는 리포좀