FI950062A0 - Fotoaktivation av proteiner för konjugationsändamål - Google Patents

Fotoaktivation av proteiner för konjugationsändamål

Info

Publication number
FI950062A0
FI950062A0 FI950062A FI950062A FI950062A0 FI 950062 A0 FI950062 A0 FI 950062A0 FI 950062 A FI950062 A FI 950062A FI 950062 A FI950062 A FI 950062A FI 950062 A0 FI950062 A0 FI 950062A0
Authority
FI
Finland
Prior art keywords
photoactivation
proteins
reactive
conjugation purposes
bonds
Prior art date
Application number
FI950062A
Other languages
English (en)
Finnish (fi)
Other versions
FI950062A (sv
Inventor
Thomas R Sykes
Thomas K Woo
Pei Qi
Antoine A Noujaim
Original Assignee
Biomira Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomira Research Inc filed Critical Biomira Research Inc
Publication of FI950062A0 publication Critical patent/FI950062A0/sv
Publication of FI950062A publication Critical patent/FI950062A/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/081Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the protein being an albumin, e.g. human serum albumin [HSA], bovine serum albumin [BSA], ovalbumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/534Production of labelled immunochemicals with radioactive label
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/804Radioisotope, e.g. radioimmunoassay
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/815Test for named compound or class of compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Optics & Photonics (AREA)
  • Analytical Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FI950062A 1992-07-06 1995-01-05 Fotoaktivation av proteiner för konjugationsändamål FI950062A (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90826192A 1992-07-06 1992-07-06
PCT/US1993/006388 WO1994001773A1 (en) 1992-07-06 1993-07-06 Photoactivation of proteins for conjugation purposes

Publications (2)

Publication Number Publication Date
FI950062A0 true FI950062A0 (sv) 1995-01-05
FI950062A FI950062A (sv) 1995-01-05

Family

ID=25425471

Family Applications (1)

Application Number Title Priority Date Filing Date
FI950062A FI950062A (sv) 1992-07-06 1995-01-05 Fotoaktivation av proteiner för konjugationsändamål

Country Status (9)

Country Link
US (1) US6313274B1 (sv)
EP (1) EP0649532B1 (sv)
JP (1) JPH08505119A (sv)
AT (1) ATE160222T1 (sv)
CA (1) CA2137561C (sv)
DE (1) DE69315213T2 (sv)
FI (1) FI950062A (sv)
NO (1) NO950037L (sv)
WO (1) WO1994001773A1 (sv)

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US6713256B1 (en) * 1998-02-14 2004-03-30 Fraunhofer Gesellschaft zur Förderung der angewandten Forschung e.V. Fluorescent energy transfer mediated chemical activation (fetma) for the elucidation of the three-dimensional structure of biomacromolecules
JP2003519096A (ja) * 1999-08-18 2003-06-17 アルタレックス コーポレーション Muc−1抗原に対する治療用抗体およびその使用方法
EP1212465A2 (en) * 1999-09-15 2002-06-12 Miraibio Inc. Method for processing biological samples
US20020169107A1 (en) * 2001-01-19 2002-11-14 Mallinckrodt Inc. Novel aromatic azides for type I phototherapy
US20030017164A1 (en) * 2001-07-03 2003-01-23 Mallinckrodt Inc. Dye-azide compounds for dual phototherapy
GB0019412D0 (en) 2000-08-08 2000-09-27 Univ York New imaging agent
US7914815B2 (en) 2000-08-16 2011-03-29 Encore Health, Llc Method for delivery of pharmaceuticals for treating or preventing presbyopia
US8697109B2 (en) 2000-08-16 2014-04-15 Encore Health, Llc Caged mercaptan and seleno-mercaptan compounds and methods of using them
US8647612B2 (en) 2008-03-05 2014-02-11 Encore Health, Llc Dithiol compounds, derivatives, and treatment of presbyopia
US7935332B2 (en) 2000-08-16 2011-05-03 Encore Health, Llc Presbyopia treatment by lens alteration
JP2005517042A (ja) * 2002-02-12 2005-06-09 ヴィスタテック・ヨーク・リミテッド 生体分子を放射性標識する方法
JPWO2004056872A1 (ja) * 2002-12-20 2006-04-20 三菱ウェルファーマ株式会社 タンパク質のチオール基を保護する方法
ATE400602T1 (de) 2002-12-31 2008-07-15 Nektar Therapeutics Al Corp Verfahren zur herstellung von hydrogelen aus thiosulfonat-zusammensetzungen und ihre verwendungen
EP1587839B1 (en) * 2003-01-22 2008-10-08 Bionanophotonics A/S Light induced immobilisation
EP1899381A1 (en) * 2005-06-27 2008-03-19 Bionanophotonics A/S Immobilisation of polypeptides by irradiation
WO2008077406A2 (en) * 2006-12-22 2008-07-03 Aalborg Universitet Coupling of elements
DE102008010436A1 (de) * 2008-02-21 2009-09-03 Berthold Technologies Gmbh & Co. Kg Vorrichtung und Verfahren zur Messung von Lumineszenz und Fluoreszenz von transfizierten Zellen oder Organteilen
US9044439B2 (en) 2008-03-05 2015-06-02 Encore Health, Llc Low dose lipoic and pharmaceutical compositions and methods
WO2009111635A2 (en) 2008-03-05 2009-09-11 Encore Health, Llc Dithiol compounds, derivatives, and uses therefor
CA2639003A1 (en) * 2008-08-20 2010-02-20 Canadian Blood Services Inhibition of fc.gamma.r-mediated phagocytosis with reduced immunoglobulin preparations
PL2821405T3 (pl) 2009-06-15 2017-08-31 Encore Health, Llc Estry cholinowe do leczenia prezbiopii i zaćmy
WO2010147957A2 (en) 2009-06-15 2010-12-23 Encore Health, Llc Dithiol compounds, derivatives, and uses therefor
CN112641720A (zh) 2014-03-03 2021-04-13 诺华股份有限公司 硫辛酸胆碱酯组合物及使用方法
CZ309221B6 (cs) * 2018-09-27 2022-06-01 Mendelova Univerzita V Brně Způsob identifikace přírodních vzorků, zejména kapalných
TWI754939B (zh) * 2020-05-26 2022-02-11 國立清華大學 不可逆共價鍵醣蛋白固定方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4202323A (en) * 1978-04-28 1980-05-13 Herz Matthew L Drug activation by radiation
US4424200A (en) 1979-05-14 1984-01-03 Nuc Med Inc. Method for radiolabeling proteins with technetium-99m
US4612007A (en) 1981-06-16 1986-09-16 Edelson Richard Leslie Method and system for externally treating the blood
US4867973A (en) 1984-08-31 1989-09-19 Cytogen Corporation Antibody-therapeutic agent conjugates
US4443427A (en) 1982-06-21 1984-04-17 Sidney Farber Cancer Institute, Inc. Monoclonal antibody
US4741900A (en) 1982-11-16 1988-05-03 Cytogen Corporation Antibody-metal ion complexes
US4713326A (en) 1983-07-05 1987-12-15 Molecular Diagnostics, Inc. Coupling of nucleic acids to solid support by photochemical methods
US4625014A (en) 1984-07-10 1986-11-25 Dana-Farber Cancer Institute, Inc. Cell-delivery agent
US4689310A (en) 1984-09-21 1987-08-25 Ortho Diagnostic Systems Inc. Methods for attaching ligands or anti-ligands to a solid phase
DE3435744C2 (de) 1984-09-28 1986-08-07 Organogen Medizinisch-Molekularbiologische Forschungsgesellschaft mbH, 6900 Heidelberg Trägermaterial zur Verwendung für Immunbestimmungen
US4597999A (en) 1984-10-04 1986-07-01 The Hospital For Sick Children Method for coupling a hydrocarbon containing molecular species
DE3728599A1 (de) * 1986-12-10 1988-06-23 Hoechst Ag Verfahren zur herstellung einer mit technetium-99m-markierten organspezifischen substanz
US5061641A (en) * 1988-04-01 1991-10-29 Immunomedics, Inc. Method for radiolabeling proteins
JPH02140286A (ja) * 1988-08-08 1990-05-29 Biomira Inc キレート化グループ置換ポリ(アミノ)酸化合物、キレート化合物グループの生体分子への光化学的付加用組成物および付加方法
US5078985A (en) * 1989-08-09 1992-01-07 Rhomed, Incorporated Radiolabeling antibodies and other proteins with technetium or rhenium by regulated reduction

Also Published As

Publication number Publication date
ATE160222T1 (de) 1997-11-15
NO950037D0 (no) 1995-01-05
AU675235B2 (en) 1997-01-30
DE69315213T2 (de) 1998-03-19
EP0649532B1 (en) 1997-11-12
JPH08505119A (ja) 1996-06-04
AU4666893A (en) 1994-01-31
CA2137561C (en) 2001-10-23
EP0649532A1 (en) 1995-04-26
NO950037L (no) 1995-01-05
DE69315213D1 (de) 1997-12-18
WO1994001773A1 (en) 1994-01-20
FI950062A (sv) 1995-01-05
US6313274B1 (en) 2001-11-06
CA2137561A1 (en) 1994-01-20

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