FI941699A0 - Atsabisyklo-aryyliasetyleeni- ja arylenyynioksiimit kolinenergisina aineina ja hoitomenetelmät - Google Patents
Atsabisyklo-aryyliasetyleeni- ja arylenyynioksiimit kolinenergisina aineina ja hoitomenetelmätInfo
- Publication number
- FI941699A0 FI941699A0 FI941699A FI941699A FI941699A0 FI 941699 A0 FI941699 A0 FI 941699A0 FI 941699 A FI941699 A FI 941699A FI 941699 A FI941699 A FI 941699A FI 941699 A0 FI941699 A0 FI 941699A0
- Authority
- FI
- Finland
- Prior art keywords
- oxime
- azabicycloarylacetylene
- arylene
- treatment
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Carbon And Carbon Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/778,412 US5306718A (en) | 1990-03-06 | 1991-10-16 | Oxime and amine substituted azabicyclo and azocyclo muscarinic agonists and methods of treatment |
US77841291 | 1991-10-16 | ||
PCT/US1992/008642 WO1993008192A1 (en) | 1991-10-16 | 1992-10-09 | Azabicyclo arylacetylene and arylenyne oximes as cholinergic agents and methods of treatment |
US9208642 | 1992-10-09 |
Publications (3)
Publication Number | Publication Date |
---|---|
FI941699A0 true FI941699A0 (fi) | 1994-04-13 |
FI941699A FI941699A (fi) | 1994-04-13 |
FI106797B FI106797B (fi) | 2001-04-12 |
Family
ID=25113261
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI941699A FI106797B (fi) | 1991-10-16 | 1994-04-13 | Menetelmä atsabisyklo [2.2.1] heptan-3-onioksiimien valmistamiseksi |
Country Status (17)
Country | Link |
---|---|
US (2) | US5306718A (fi) |
EP (1) | EP0608336B1 (fi) |
JP (1) | JP3367670B2 (fi) |
KR (1) | KR100241479B1 (fi) |
AT (1) | ATE166354T1 (fi) |
AU (1) | AU658685B2 (fi) |
CA (1) | CA2115443C (fi) |
DE (1) | DE69225601T2 (fi) |
DK (1) | DK0608336T3 (fi) |
ES (1) | ES2119823T3 (fi) |
FI (1) | FI106797B (fi) |
NO (1) | NO302072B1 (fi) |
NZ (1) | NZ244726A (fi) |
PH (1) | PH31431A (fi) |
PT (1) | PT100961B (fi) |
WO (1) | WO1993008192A1 (fi) |
ZA (1) | ZA927973B (fi) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5346911A (en) * | 1990-03-06 | 1994-09-13 | Warner-Lambert Company | Azabicyclo and azacyclo oxime and amine cholinergic agents and methods of treatment |
US5514812A (en) * | 1994-06-10 | 1996-05-07 | Warner-Lambert Company | Preparation of stereochemically pure oximes with muscarinic activity |
AUPM910994A0 (en) * | 1994-10-28 | 1994-11-24 | Commonwealth Scientific And Industrial Research Organisation | Bisallyloxyimides |
US5534522A (en) * | 1995-06-07 | 1996-07-09 | Warner-Lambert Company | (R)-(Z)-1-azabicyclo [2.2.1] heptan-3-one,O-[3-(3-methoxyphenyl)-2-propynyl] oxime maleate as a pharmaceutical agent |
US6168912B1 (en) | 1996-01-23 | 2001-01-02 | Martek Biosciences Corporation | Method and kit for making a multidimensional combinatorial chemical library |
NZ335784A (en) * | 1997-01-27 | 2000-12-22 | Warner Lambert Co | Process for isolation of (z)-azabicyclo oxime ethers by reacting an O-substituted hydroxylamine with an azabicycloketone |
US6924313B1 (en) | 1999-09-23 | 2005-08-02 | Pfizer Inc. | Substituted tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity |
US6544974B2 (en) * | 1999-09-23 | 2003-04-08 | G.D. Searle & Co. | (R)-chiral halogenated substituted fused heterocyclic amino compounds useful for inhibiting cholesteryl ester transfer protein activity |
EP2147679B1 (en) | 2001-07-25 | 2014-06-25 | Raptor Pharmaceutical, Inc. | Compositions for blood-brain barrier transport |
KR100465277B1 (ko) * | 2002-01-24 | 2005-01-13 | 한국과학기술연구원 | 신규한 옥심계 아자 두 고리 화합물 및 그 제조방법 |
DK1889198T3 (da) | 2005-04-28 | 2015-02-09 | Proteus Digital Health Inc | Farma-informatiksystem |
WO2008036682A2 (en) | 2006-09-18 | 2008-03-27 | Raptor Pharmaceutical Inc. | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
DK2398500T3 (da) | 2009-02-20 | 2019-05-13 | 2 Bbb Medicines B V | Glutathion-baseret lægemiddelafgivelsessystem |
IL255113B (en) | 2009-05-06 | 2022-09-01 | Laboratory Skin Care Inc | Preparations for administration through the skin that include complexes of an active substance with calcium phosphate and methods of using them |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3381012A (en) * | 1961-08-08 | 1968-04-30 | Sterling Drug Inc | Primary, secondary, and tertiary-(1-piperidyl)-lower-alkylamines |
US3502692A (en) * | 1962-06-13 | 1970-03-24 | American Cyanamid Co | Cyclic nitroxides and process for preparing same |
DE2019536A1 (de) * | 1970-04-23 | 1971-11-11 | Basf Ag | Oximcarbamate |
DE2552176A1 (de) * | 1975-11-21 | 1977-06-02 | Hoechst Ag | Neue piperidin-derivate, ihre herstellung und verwendung |
US4341795A (en) * | 1975-12-01 | 1982-07-27 | Union Carbide Corporation | Asymmetrical bis-carbamate compounds |
US4710508A (en) * | 1986-12-08 | 1987-12-01 | Warner-Lambert Company | O-substituted tetrahydropyridine oxime cholinergic agents |
NZ226000A (en) * | 1987-09-10 | 1991-06-25 | Merck Sharp & Dohme | Oxadiazolyl-azabicycloheptanes and pharmaceutical compositions |
US4937239A (en) * | 1989-02-13 | 1990-06-26 | Warner-Lambert Company | Azabicycloalkane oxime & azabicycloalkene oxime muscarinic agents |
IL97266A0 (en) * | 1990-03-06 | 1992-05-25 | Warner Lambert Co | Azabicyclo and azacyclo oximes and amines,their preparation and pharmaceutical compositions containing them |
-
1991
- 1991-10-16 US US07/778,412 patent/US5306718A/en not_active Expired - Fee Related
-
1992
- 1992-10-09 DE DE69225601T patent/DE69225601T2/de not_active Expired - Fee Related
- 1992-10-09 AT AT92921974T patent/ATE166354T1/de not_active IP Right Cessation
- 1992-10-09 CA CA002115443A patent/CA2115443C/en not_active Expired - Fee Related
- 1992-10-09 WO PCT/US1992/008642 patent/WO1993008192A1/en active IP Right Grant
- 1992-10-09 AU AU27835/92A patent/AU658685B2/en not_active Ceased
- 1992-10-09 ES ES92921974T patent/ES2119823T3/es not_active Expired - Lifetime
- 1992-10-09 KR KR1019940701231A patent/KR100241479B1/ko not_active IP Right Cessation
- 1992-10-09 JP JP50773793A patent/JP3367670B2/ja not_active Expired - Fee Related
- 1992-10-09 EP EP92921974A patent/EP0608336B1/en not_active Expired - Lifetime
- 1992-10-09 DK DK92921974T patent/DK0608336T3/da active
- 1992-10-14 NZ NZ244726A patent/NZ244726A/en unknown
- 1992-10-14 PH PH45704A patent/PH31431A/en unknown
- 1992-10-15 ZA ZA927973A patent/ZA927973B/xx unknown
- 1992-10-15 PT PT100961A patent/PT100961B/pt active IP Right Grant
-
1994
- 1994-02-01 US US08/189,620 patent/US5482938A/en not_active Expired - Fee Related
- 1994-04-13 FI FI941699A patent/FI106797B/fi active
- 1994-04-15 NO NO941365A patent/NO302072B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NO302072B1 (no) | 1998-01-19 |
CA2115443C (en) | 2003-05-13 |
AU2783592A (en) | 1993-05-21 |
DE69225601D1 (de) | 1998-06-25 |
DE69225601T2 (de) | 1998-12-17 |
ES2119823T3 (es) | 1998-10-16 |
CA2115443A1 (en) | 1993-04-29 |
JPH07500337A (ja) | 1995-01-12 |
KR100241479B1 (ko) | 2000-03-02 |
JP3367670B2 (ja) | 2003-01-14 |
WO1993008192A1 (en) | 1993-04-29 |
ATE166354T1 (de) | 1998-06-15 |
AU658685B2 (en) | 1995-04-27 |
US5482938A (en) | 1996-01-09 |
EP0608336B1 (en) | 1998-05-20 |
FI941699A (fi) | 1994-04-13 |
ZA927973B (en) | 1994-04-15 |
EP0608336A1 (en) | 1994-08-03 |
NO941365L (no) | 1994-04-15 |
PT100961A (pt) | 1993-11-30 |
NZ244726A (en) | 1995-09-26 |
PT100961B (pt) | 1999-07-30 |
FI106797B (fi) | 2001-04-12 |
NO941365D0 (no) | 1994-04-15 |
US5306718A (en) | 1994-04-26 |
DK0608336T3 (da) | 1999-01-18 |
PH31431A (en) | 1998-11-03 |
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