BG103271A - Derivatives of n-(benzothiazol-2-yl) piperidine-1-ethaneamines, method for their preparation and application as therapeutical means - Google Patents

Derivatives of n-(benzothiazol-2-yl) piperidine-1-ethaneamines, method for their preparation and application as therapeutical means

Info

Publication number
BG103271A
BG103271A BG103271A BG10327199A BG103271A BG 103271 A BG103271 A BG 103271A BG 103271 A BG103271 A BG 103271A BG 10327199 A BG10327199 A BG 10327199A BG 103271 A BG103271 A BG 103271A
Authority
BG
Bulgaria
Prior art keywords
ethaneamines
benzothiazol
piperidine
derivatives
preparation
Prior art date
Application number
BG103271A
Other languages
Bulgarian (bg)
Inventor
Gihad Dargazanli
Pascal George
Patrick Lardenois
Jonathan Frost
Johannes Schoemaker
Maria-Carmen Renones
Pascale Magat
Original Assignee
Sanofi-Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Synthelabo filed Critical Sanofi-Synthelabo
Publication of BG103271A publication Critical patent/BG103271A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Abstract

The invention relates to compounds with the general formula where n has the value of 0, 1,2 or 3, R1 means hydrogen or halogen, of methyl group, or methoxygroup, R2 is hydrogen or methyl group, R3 means hydrogen or one or two halogen atoms. 4 claims
BG103271A 1996-10-01 1999-03-22 Derivatives of n-(benzothiazol-2-yl) piperidine-1-ethaneamines, method for their preparation and application as therapeutical means BG103271A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9611925A FR2753970B1 (en) 1996-10-01 1996-10-01 N- (BENZOTHIAZOL-2-YL) PIPERIDINE-1-ETHANAMINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
PCT/FR1997/001692 WO1998014444A1 (en) 1996-10-01 1997-09-26 N-(benzothiazol-2-yl) piperidine-1-ethanamine derivatives, their preparation and application in therapeutics

Publications (1)

Publication Number Publication Date
BG103271A true BG103271A (en) 2000-05-31

Family

ID=9496217

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103271A BG103271A (en) 1996-10-01 1999-03-22 Derivatives of n-(benzothiazol-2-yl) piperidine-1-ethaneamines, method for their preparation and application as therapeutical means

Country Status (23)

Country Link
EP (1) EP0929550A1 (en)
JP (1) JP2001501217A (en)
KR (1) KR20000048767A (en)
CN (1) CN1230959A (en)
AR (1) AR009105A1 (en)
AU (1) AU722147B2 (en)
BG (1) BG103271A (en)
BR (1) BR9711842A (en)
CA (1) CA2266510A1 (en)
CO (1) CO4650030A1 (en)
CZ (1) CZ112699A3 (en)
EE (1) EE9900135A (en)
FR (1) FR2753970B1 (en)
HU (1) HUP9904091A3 (en)
IL (1) IL128902A (en)
NO (1) NO991581L (en)
NZ (1) NZ334553A (en)
PL (1) PL332648A1 (en)
SK (1) SK42299A3 (en)
TR (1) TR199900634T2 (en)
TW (1) TW438800B (en)
WO (1) WO1998014444A1 (en)
ZA (1) ZA978772B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9725541D0 (en) * 1997-12-02 1998-02-04 Pharmacia & Upjohn Spa Amino-benzothiazole derivatives
US6107313A (en) * 1998-10-02 2000-08-22 Combichem, Inc. Dopamine receptor antagonists
YU96502A (en) 2000-06-21 2006-01-16 F. Hoffmann-La Roche Ag. Benzothiazole derivatives
US7087761B2 (en) 2003-01-07 2006-08-08 Hoffmann-La Roche Inc. Cyclization process for substituted benzothiazole derivatives
JP2007509095A (en) * 2003-10-24 2007-04-12 エフ．ホフマン−ラ　ロシュ　アーゲー CCR3 receptor antagonist
WO2005116026A1 (en) 2004-05-24 2005-12-08 F. Hoffmann-La Roche Ag 4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide
DE602005008095D1 (en) 2004-11-05 2008-08-21 Hoffmann La Roche PROCESS FOR THE PREPARATION OF ISONICOTINIC ACID DERIVATIVES
WO2006099972A1 (en) 2005-03-23 2006-09-28 F. Hoffmann-La Roche Ag Acetylenyl-pyrazolo-pvrimidine derivatives as mglur2 antagonists
ES2340321T3 (en) 2005-09-27 2010-06-01 F.Hoffmann-La Roche Ag OXADIAZOLILPIRAZOLO-PIRIMIDINAS, AS ANGLGIST OF MGLUR2.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1260474A (en) * 1984-12-03 1989-09-26 Raymond A. Stokbroekx Benzoxazol- and benzothiazolamine derivatives
KR930005004B1 (en) * 1985-04-15 1993-06-11 쟈안센 파아마슈우티카 엔. 부이. Process for preparing substituted n-|(4-piperidinyl) alkyl¨ bicycle condensed oxazole and thiazolamines

Also Published As

Publication number Publication date
EP0929550A1 (en) 1999-07-21
AU722147B2 (en) 2000-07-20
NO991581L (en) 1999-06-01
CZ112699A3 (en) 1999-06-16
IL128902A (en) 2001-07-24
AU4463897A (en) 1998-04-24
AR009105A1 (en) 2000-03-08
CN1230959A (en) 1999-10-06
ZA978772B (en) 1998-03-27
HUP9904091A2 (en) 2000-05-28
SK42299A3 (en) 1999-12-10
FR2753970A1 (en) 1998-04-03
CO4650030A1 (en) 1998-09-03
TR199900634T2 (en) 1999-06-21
IL128902A0 (en) 2000-02-17
BR9711842A (en) 1999-08-24
FR2753970B1 (en) 1998-10-30
NO991581D0 (en) 1999-03-30
PL332648A1 (en) 1999-09-27
EE9900135A (en) 1999-12-15
HUP9904091A3 (en) 2000-07-28
TW438800B (en) 2001-06-07
WO1998014444A1 (en) 1998-04-09
CA2266510A1 (en) 1998-04-09
NZ334553A (en) 2000-11-24
KR20000048767A (en) 2000-07-25
JP2001501217A (en) 2001-01-30

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