FI875297A - Nya pyrrolderivat, deras framstaellning och dessa innehaollande farmaceutiska produkter. - Google Patents

Nya pyrrolderivat, deras framstaellning och dessa innehaollande farmaceutiska produkter. Download PDF

Info

Publication number: FI875297A
Authority: FI; Finland
Prior art keywords: pyrrolidinyl; alkyl; piperidyl; piperazinyl; unsubstituted
Prior art date: 1986-12-02

Application number

FI875297A

Other languages

English (en)

Other versions

FI875297A0 (fi

FI84721B (fi

FI84721C (fi

Inventor

Jean-Dominique Bourzat

Marc Capet

Claude Cotrel

Richard Labaudiniere

Philippe Pitchen

Gerard Roussel

Original Assignee

Rhone Poulenc Sante

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-12-02

Filing date

1987-12-01

Publication date

1988-06-03

1987-12-01 Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante

1987-12-01 Publication of FI875297A0 publication Critical patent/FI875297A0/fi

1988-06-03 Publication of FI875297A publication Critical patent/FI875297A/fi

1991-09-30 Publication of FI84721B publication Critical patent/FI84721B/fi

1992-01-10 Application granted granted Critical

1992-01-10 Publication of FI84721C publication Critical patent/FI84721C/fi

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Neurology (AREA)
Animal Behavior & Ethology (AREA)
Pain & Pain Management (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Orthopedic Medicine & Surgery (AREA)
Anesthesiology (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pyrrole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicinal Preparation (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Indole Compounds (AREA)
Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

FI875297A 1986-12-02 1987-12-01 Foerfarande foer framstaellning av terapeutiskt aktiva 2-(1,8-naftyridin-2-yl)-isoindolin-1-oner. FI84721C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8616794A FR2607506B1 (fr)	1986-12-02	1986-12-02	Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
FR8616794		1986-12-02

Publications (4)

Publication Number	Publication Date
FI875297A0 FI875297A0 (fi)	1987-12-01
FI875297A true FI875297A (fi)	1988-06-03
FI84721B FI84721B (fi)	1991-09-30
FI84721C FI84721C (fi)	1992-01-10

Family

ID=9341441

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI875297A FI84721C (fi)	1986-12-02	1987-12-01	Foerfarande foer framstaellning av terapeutiskt aktiva 2-(1,8-naftyridin-2-yl)-isoindolin-1-oner.

Country Status (23)

Country	Link
US (1)	US4898871A (fi)
EP (1)	EP0274929B1 (fi)
JP (1)	JPS63154686A (fi)
KR (1)	KR880007515A (fi)
AT (1)	ATE66227T1 (fi)
AU (1)	AU594538B2 (fi)
CA (1)	CA1298294C (fi)
DE (1)	DE3772187D1 (fi)
DK (1)	DK630587A (fi)
ES (1)	ES2038686T3 (fi)
FI (1)	FI84721C (fi)
FR (1)	FR2607506B1 (fi)
GR (1)	GR3002472T3 (fi)
HU (1)	HU199467B (fi)
IL (1)	IL84656A (fi)
MA (1)	MA21116A1 (fi)
MX (1)	MX9557A (fi)
NO (1)	NO166183C (fi)
NZ (1)	NZ222750A (fi)
OA (1)	OA08695A (fi)
PT (1)	PT86259B (fi)
SU (5)	SU1588280A3 (fi)
ZA (1)	ZA878999B (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2607503B1 (fr) *	1986-12-02	1989-02-24	Rhone Poulenc Sante	Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2607504B1 (fr) *	1986-12-02	1989-01-27	Rhone Poulenc Sante	Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
HUE061595T2 (hu)	2017-12-21	2023-07-28	Ribon Therapeutics Inc	Kinazolinonok mint PARP14 inhibitorok
CN112138003A (zh) *	2019-06-27	2020-12-29	中山大学	3-正丁基-异吲哚啉-1-酮在镇静、抗惊厥和抗癫痫的药物中的应用
WO2023192782A2 (en) *	2022-03-27	2023-10-05	Board Of Regents, The University Of Texas System	Small molecule inhibitors of lanosterol synthase

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR203996A1 (es) *	1972-03-16	1975-11-12	Rhone Poulenc Sa	Procedimiento para preparar derivados de(hidroxi-2-amino-3-propoxi)-3-isoindolinona-1
US4000306A (en) *	1973-02-08	1976-12-28	Rhone-Poulenc S.A.	Anti-arrhythmic compositions containing isoindoline derivatives
FR2217000B1 (fi) *	1973-02-08	1976-04-09	Rhone Poulenc Ind
AR208414A1 (es) *	1974-11-07	1976-12-27	Rhone Poulenc Ind	Procedimiento para obtener nuevos derivados de la((acil-4piperazinil-1)carboniloxi-5 pirrolinona-2)
CS274601B2 (en) *	1983-07-27	1991-09-15	Dainippon Pharmaceutical Co	Method of 1,8-naphthyridine derivative production
US4657913A (en) *	1985-04-18	1987-04-14	Warner-Lambert Company	Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents
NZ218773A (en) *	1986-01-06	1990-05-28	Carpibem	3-methyl-2-oxo-1-(substituted phenyl)-naphthyridines and pharmaceutical compositions
FR2607503B1 (fr) *	1986-12-02	1989-02-24	Rhone Poulenc Sante	Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2607504B1 (fr) *	1986-12-02	1989-01-27	Rhone Poulenc Sante	Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent

1986
- 1986-12-02 FR FR8616794A patent/FR2607506B1/fr not_active Expired
1987
- 1987-11-27 MA MA21357A patent/MA21116A1/fr unknown
- 1987-11-29 IL IL84656A patent/IL84656A/xx unknown
- 1987-11-30 NZ NZ222750A patent/NZ222750A/xx unknown
- 1987-11-30 AU AU81917/87A patent/AU594538B2/en not_active Ceased
- 1987-11-30 US US07/126,352 patent/US4898871A/en not_active Expired - Fee Related
- 1987-11-30 ZA ZA878999A patent/ZA878999B/xx unknown
- 1987-12-01 SU SU874203789A patent/SU1588280A3/ru active
- 1987-12-01 ES ES198787402706T patent/ES2038686T3/es not_active Expired - Lifetime
- 1987-12-01 DE DE8787402706T patent/DE3772187D1/de not_active Expired - Fee Related
- 1987-12-01 MX MX955787A patent/MX9557A/es unknown
- 1987-12-01 EP EP87402706A patent/EP0274929B1/fr not_active Expired - Lifetime
- 1987-12-01 AT AT87402706T patent/ATE66227T1/de not_active IP Right Cessation
- 1987-12-01 FI FI875297A patent/FI84721C/fi not_active IP Right Cessation
- 1987-12-01 HU HU875399A patent/HU199467B/hu not_active IP Right Cessation
- 1987-12-01 NO NO875010A patent/NO166183C/no unknown
- 1987-12-01 KR KR870013647A patent/KR880007515A/ko not_active Application Discontinuation
- 1987-12-01 DK DK630587A patent/DK630587A/da not_active Application Discontinuation
- 1987-12-01 CA CA000553249A patent/CA1298294C/fr not_active Expired - Lifetime
- 1987-12-02 PT PT86259A patent/PT86259B/pt not_active IP Right Cessation
- 1987-12-02 JP JP62303418A patent/JPS63154686A/ja active Pending
- 1987-12-02 OA OA59234A patent/OA08695A/xx unknown
1988
- 1988-12-15 SU SU884613006A patent/SU1612997A3/ru active
- 1988-12-15 SU SU884613053A patent/SU1575937A3/ru active
- 1988-12-15 SU SU884613037A patent/SU1678202A3/ru active
- 1988-12-15 SU SU884356998A patent/SU1627083A3/ru active
1991
- 1991-08-16 GR GR91400231T patent/GR3002472T3/el unknown

Also Published As

Publication number	Publication date
CA1298294C (fr)	1992-03-31
AU8191787A (en)	1988-06-02
KR880007515A (ko)	1988-08-27
HU199467B (en)	1990-02-28
FI875297A0 (fi)	1987-12-01
DK630587A (da)	1988-06-03
FR2607506A1 (fr)	1988-06-03
ES2038686T3 (es)	1993-08-01
AU594538B2 (en)	1990-03-08
ATE66227T1 (de)	1991-08-15
HUT46008A (en)	1988-09-28
FI84721B (fi)	1991-09-30
NO875010D0 (no)	1987-12-01
IL84656A0 (en)	1988-04-29
OA08695A (fr)	1989-03-31
SU1588280A3 (ru)	1990-08-23
SU1612997A3 (ru)	1990-12-07
MA21116A1 (fr)	1988-07-01
EP0274929B1 (fr)	1991-08-14
NO166183C (no)	1991-06-12
NZ222750A (en)	1989-10-27
US4898871A (en)	1990-02-06
PT86259B (pt)	1990-11-07
DE3772187D1 (de)	1991-09-19
JPS63154686A (ja)	1988-06-27
NO875010L (no)	1988-06-03
MX9557A (es)	1993-10-01
SU1678202A3 (ru)	1991-09-15
IL84656A (en)	1991-12-15
ZA878999B (en)	1988-07-27
PT86259A (fr)	1988-01-01
FI84721C (fi)	1992-01-10
SU1575937A3 (ru)	1990-06-30
GR3002472T3 (en)	1992-12-30
EP0274929A1 (fr)	1988-07-20
DK630587D0 (da)	1987-12-01
NO166183B (no)	1991-03-04
SU1627083A3 (ru)	1991-02-07
FR2607506B1 (fr)	1989-01-06

Legal Events

Date	Code	Title	Description
2004-08-31	MM	Patent lapsed	Owner name: RHONE-POULENC SANTE

Publication	Publication Date	Title
FI875298A0 (fi)	1987-12-01	Nya pyrrolderivat, deras framstaellning och dessa innehaollande farmaceutiska produkter.
FI875297A (fi)	1988-06-03	Nya pyrrolderivat, deras framstaellning och dessa innehaollande farmaceutiska produkter.
NZ222752A (en)	1989-10-27	Naphthyridinyl-, pyridyl-, or quinolyl- substituted pyrrole derivatives and pharmaceutical composition