FI852377L - Process for producing erythropoietin and DNA sequences used therewith - Google Patents

Process for producing erythropoietin and DNA sequences used therewith

Info

Publication number
FI852377L
FI852377L FI852377A FI852377A FI852377L FI 852377 L FI852377 L FI 852377L FI 852377 A FI852377 A FI 852377A FI 852377 A FI852377 A FI 852377A FI 852377 L FI852377 L FI 852377L
Authority
FI
Finland
Prior art keywords
epo
dna
dna sequences
relates
cdna
Prior art date
Application number
FI852377A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI93470C (en
FI93470B (en
FI852377A0 (en
Inventor
Fu-Kuen Lin
Original Assignee
Kirin Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27097052&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI852377(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US06/675,298 external-priority patent/US4703008A/en
Application filed by Kirin Amgen Inc filed Critical Kirin Amgen Inc
Publication of FI852377A0 publication Critical patent/FI852377A0/en
Publication of FI852377L publication Critical patent/FI852377L/en
Priority to FI890498A priority Critical patent/FI890498A0/en
Application granted granted Critical
Publication of FI93470B publication Critical patent/FI93470B/en
Publication of FI93470C publication Critical patent/FI93470C/en

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Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention relates to novel polypeptides which partially or entirely correspond to the primary structure of, and possess one or more of the biological properties of, mammalian erythropoietin ("EPO"), which is characterised, in preferred forms, in that it constitutes the product of prokaryotic or eukaryotic host expression of an exogenous DNA sequence. The invention is illustrated by the fact that genomic DNA, cDNA or prepared DNA sequences, which partially or entirely encode the sequence of the amino acid residues of EPO, or analogues thereof, is/are incorporated into autonomously replicating plasmid or virus vectors, which are used for transforming or transfecting suitable prokaryotic or eukaryotic host cells such as bacteria, yeast or vertebrate cells in culture. After isolation from culture media or cellular lysates or fragments, the expression products of the DNA sequences exhibit, for example, the immunological properties and the biological activities of human or monkey EPO both in vitro and in vivo. The invention also relates to chemically synthesised polypeptides which share the biochemical and immunological properties of EPO. The invention also relates to improved methods for detecting specific single stranded polynucleotides in a heterologous cell or virus sample which has been prepared, for example, from DNA which is present in a plasmid-generated or virusgenerated cDNA or genomic DNA "library"
FI852377A 1984-09-28 1985-06-14 Process for producing erythropoietin and DNA sequences used therewith FI93470C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI890498A FI890498A0 (en) 1984-09-28 1989-02-02 ERYTHROPOIETY OCH PAO DETTA RIKTADE ANTIKROPPAR.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65584184A 1984-09-28 1984-09-28
US06/675,298 US4703008A (en) 1983-12-13 1984-11-30 DNA sequences encoding erythropoietin

Publications (4)

Publication Number Publication Date
FI852377A0 FI852377A0 (en) 1985-06-14
FI852377L true FI852377L (en) 1986-03-29
FI93470B FI93470B (en) 1994-12-30
FI93470C FI93470C (en) 1995-04-10

Family

ID=27097052

Family Applications (1)

Application Number Title Priority Date Filing Date
FI852377A FI93470C (en) 1984-09-28 1985-06-14 Process for producing erythropoietin and DNA sequences used therewith

Country Status (9)

Country Link
CN (1) CN1016795B (en)
CZ (1) CZ281542B6 (en)
FI (1) FI93470C (en)
GE (1) GEP19991639B (en)
GR (1) GR852245B (en)
HU (1) HU204889B (en)
NO (1) NO852384L (en)
PT (1) PT81213B (en)
SK (1) SK279959B6 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106608906A (en) * 2015-10-22 2017-05-03 天津药物研究院有限公司 Preparation of annular polypeptide with function of stimulating erythrocyte generation and application thereof

Also Published As

Publication number Publication date
PT81213A (en) 1985-10-01
FI93470C (en) 1995-04-10
CN1016795B (en) 1992-05-27
GR852245B (en) 1986-01-17
CN85106191A (en) 1987-07-29
GEP19991639B (en) 1999-03-23
SK443885A3 (en) 1999-06-11
NO852384L (en) 1986-04-01
PT81213B (en) 1987-09-30
CZ281542B6 (en) 1996-11-13
HU204889B (en) 1992-02-28
HUT40694A (en) 1987-01-28
CZ443885A3 (en) 1996-09-11
FI93470B (en) 1994-12-30
SK279959B6 (en) 1999-06-11
FI852377A0 (en) 1985-06-14

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Legal Events

Date Code Title Description
BB Publication of examined application
FG Patent granted

Owner name: KIRIN-AMGEN, INC.

MA Patent expired