FI834137A0 - Bensodiazepinreceptoraktiva foereningar och foerfarande foer deras framstaellning - Google Patents

Bensodiazepinreceptoraktiva foereningar och foerfarande foer deras framstaellning

Info

Publication number
FI834137A0
FI834137A0 FI834137A FI834137A FI834137A0 FI 834137 A0 FI834137 A0 FI 834137A0 FI 834137 A FI834137 A FI 834137A FI 834137 A FI834137 A FI 834137A FI 834137 A0 FI834137 A0 FI 834137A0
Authority
FI
Finland
Prior art keywords
hydrogen
bensodiazepinreceptoraktiva
foerfarande foer
formula
image
Prior art date
Application number
FI834137A
Other languages
English (en)
Other versions
FI834137A (fi
FI78095C (fi
FI78095B (fi
Inventor
Claus Thyco Braestrup
Joergen Anders Christensen
Mogens Engelstoft
Frank Waetjen
Original Assignee
Ferrosan As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrosan As filed Critical Ferrosan As
Publication of FI834137A0 publication Critical patent/FI834137A0/fi
Publication of FI834137A publication Critical patent/FI834137A/fi
Application granted granted Critical
Publication of FI78095B publication Critical patent/FI78095B/fi
Publication of FI78095C publication Critical patent/FI78095C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI834137A 1982-11-16 1983-11-11 Foerfarande foer framstaellning av som psykofarmaceutiska medel anvaendbara oxadiazolyl-imidazo/1,4/ bensodiazepinderivat. FI78095C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK510282A DK151808C (da) 1982-11-16 1982-11-16 Analogifremgangsmaade til fremstilling af oxadiazolylimidazo-oe1,4aa-benzodiazepinderivater
DK510282 1982-11-16

Publications (4)

Publication Number Publication Date
FI834137A0 true FI834137A0 (fi) 1983-11-11
FI834137A FI834137A (fi) 1984-05-17
FI78095B FI78095B (fi) 1989-02-28
FI78095C FI78095C (fi) 1989-06-12

Family

ID=8139462

Family Applications (1)

Application Number Title Priority Date Filing Date
FI834137A FI78095C (fi) 1982-11-16 1983-11-11 Foerfarande foer framstaellning av som psykofarmaceutiska medel anvaendbara oxadiazolyl-imidazo/1,4/ bensodiazepinderivat.

Country Status (10)

Country Link
US (1) US4507313A (fi)
EP (1) EP0109921B1 (fi)
JP (1) JPS59104385A (fi)
AT (1) ATE32721T1 (fi)
DE (1) DE3375785D1 (fi)
DK (1) DK151808C (fi)
ES (3) ES527295A0 (fi)
FI (1) FI78095C (fi)
IE (1) IE56233B1 (fi)
NO (1) NO163820C (fi)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA845757B (en) * 1983-08-25 1985-04-24 Hoffmann La Roche Benzodiazepine derivatives
CA1252462A (en) * 1984-01-19 1989-04-11 Walter Hunkeler Imidazodiazepine derivatives
AU587802B2 (en) * 1985-03-08 1989-08-31 Ferrosan A/S Novel oxadiazolyl imidazobenzodiazepine derivatives and methods of preparing such compounds
US4622320A (en) * 1985-05-17 1986-11-11 As Ferrosan Oxadiazolylimidazobenzodiazepine, compositions, and method
DE202441T1 (de) * 1985-05-17 1987-03-19 Aktieselskabet Ferrosan, Soeborg Oxadiazolylimidazobenzodiazepine, verfahren zu ihrer herstellung und pharmazeutische zubereitungen.
US4745112A (en) * 1985-05-17 1988-05-17 A/S Ferrosan Oxadiazolylimidazobenzodiazepine, compositions, and method III
DK476885D0 (da) * 1985-10-17 1985-10-17 Ferrosan As Heterocycliske forbindelser og fremgangsmaader til fremstilling heraf
CA1297099C (en) * 1985-10-17 1992-03-10 Frank Watjen Quinazoline compounds and their preparation and use
DK174086D0 (da) * 1986-04-16 1986-04-16 Ferrosan As Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme
FI880814A (fi) * 1987-03-10 1988-09-11 Hoffmann La Roche Imidazodiazepin-derivat.
GB8823475D0 (en) * 1988-10-06 1988-11-16 Merck Sharp & Dohme Chemical compounds
CA2015336A1 (en) * 1989-05-19 1990-11-19 F. Hoffmann-La Roche Ag Imidazodiazepines for the treatment of neurological symptoms
US4904654A (en) * 1989-07-26 1990-02-27 Merck & Co., Inc. 7-chloro-5,6-dihydro-3-(5-(2-hydroxy-isopropyl)-1,2,4-oxadiazol-3-yl)-5-methyl-6-oxo-4H-imidazo[1,5a][1,4]benzodiazepine
US4939139A (en) * 1989-07-26 1990-07-03 Merck & Co., Inc. 7-chloro-5,6-dihydro-3-(5-(1,2-dihydroxy-isopropyl)-1,2,4-oxadiazol-3-yl)-5-methyl-6-oxo-4H-imidazo[1,5A][1,4]benzodiazepine
GB8923008D0 (en) * 1989-10-12 1989-11-29 Roussel Lab Ltd Chemical compounds
GB8927928D0 (en) * 1989-12-11 1990-02-14 Roussel Lab Ltd Chemical compounds
US5428031A (en) * 1991-12-03 1995-06-27 Merck & Co., Inc. Methods of treating cardiac arrhythmia
US5317018A (en) * 1992-06-09 1994-05-31 Armin Walser Benzodiazepines and compositions for treating anxiety and panic disorders, and idiopathic and psychomotor epilepsy
ES2162907T3 (es) * 1993-11-22 2002-01-16 Merck & Co Inc 3-acilaminobenzacepinas.
US5439906A (en) * 1993-11-22 1995-08-08 Merck & Co., Inc. Antiarrhythmic benzodiazepines
CA2143246C (en) * 1994-03-16 2000-08-22 Thierry Godel Imidazodiazepines
DK0776208T3 (da) * 1994-08-18 2000-05-01 Merck & Co Inc 2,3-dihydro-1-(2,2,2-trifluorethyl)-2-oxo-5-phenyl-1H-1,4-benzodiazepiner
US5631251A (en) * 1995-06-07 1997-05-20 Merck & Co., Inc. 5-cyclopropyl-1,4 benzodiazepine-2-ones
CA2222491A1 (en) * 1995-06-07 1996-12-19 Merck & Co., Inc. Novel n-(2,4-dioxo-2,3,4,5-tetrahydro-1h-1,5-benzodiazepin-3yl)-3-amides
US5726171A (en) * 1995-06-07 1998-03-10 Merck & Co Inc N-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo B! 1,4!diazepin-3yl)-acetamides
US5700797A (en) * 1995-06-07 1997-12-23 Merck & Co, Inc. N-(2,4-dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3-yl)-3-amides
US5691331A (en) * 1995-06-07 1997-11-25 Merck & Co., Inc. N-(2,4-Dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3yl) -3- amides
US20090054412A1 (en) * 2007-08-20 2009-02-26 John Alan Kemp Treatment of Sleep Disorders
EP2190435B1 (en) 2007-08-20 2018-05-30 Evotec International GmbH Treatment of sleep disorders
US8119629B2 (en) 2007-10-03 2012-02-21 Bristol-Meyers Squibb Company Carboxamide GABAA α2 modulators
WO2016037111A1 (en) * 2014-09-05 2016-03-10 Mazak Corporation Vertical machine tool apparatus and method

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE422580B (sv) * 1975-08-07 1982-03-15 Hoffmann La Roche Analogiforfarande for framstellning av imidazo (1,5-a)(1,4)diazepin-foreningar
CA1143728A (en) * 1979-10-04 1983-03-29 Max Gerecke Imidazodiazepine derivatives
JPS57123180A (en) * 1980-12-17 1982-07-31 Schering Ag 3-substituted beta-carboline, manufacture and psychotropic drug containing same
CA1174673A (en) * 1981-02-27 1984-09-18 Walter Hunkeler Imidazodiazepines
CA1184175A (en) * 1981-02-27 1985-03-19 Walter Hunkeler Imidazodiazepines
US4352817A (en) * 1981-02-27 1982-10-05 Hoffmann-La Roche Inc. Imidazo-diazepines and their use

Also Published As

Publication number Publication date
NO834187L (no) 1984-05-18
ES8504196A1 (es) 1985-04-16
JPS59104385A (ja) 1984-06-16
JPS635031B2 (fi) 1988-02-01
ES8507144A1 (es) 1985-09-01
DE3375785D1 (en) 1988-04-07
ES527295A0 (es) 1985-04-16
ES529149A0 (es) 1985-09-01
NO163820B (no) 1990-04-17
IE56233B1 (en) 1991-05-22
EP0109921B1 (en) 1988-03-02
FI834137A (fi) 1984-05-17
FI78095C (fi) 1989-06-12
IE832644L (en) 1984-05-15
ES529150A0 (es) 1985-09-01
DK151808C (da) 1988-06-20
EP0109921A1 (en) 1984-05-30
ATE32721T1 (de) 1988-03-15
ES8507143A1 (es) 1985-09-01
NO163820C (no) 1990-08-01
FI78095B (fi) 1989-02-28
US4507313A (en) 1985-03-26
DK510282A (da) 1984-05-17
DK151808B (da) 1988-01-04

Similar Documents

Publication Publication Date Title
FI834137A0 (fi) Bensodiazepinreceptoraktiva foereningar och foerfarande foer deras framstaellning
ES548399A0 (es) Un procedimiento para la preparacion de derivados de imida- zodiacepina
ES551990A0 (es) Procedimiento para preparar un derivados de cefalosporina.
ZA858418B (en) 5-alkyl-1-phenyl-2-piperazinoalkylpyrazoline-3-one compounds and methods for the preparation thereof,intermediates for use in the preparation of said compounds and medicaments containing said compounds
AU554959B2 (en) Triazolo(4,3-a) quinazolin-5-ones
ES2062819T3 (es) Compuestos heterociclicos, y su preparacion y uso.
MX9204194A (es) Los compuestos de 1,2,4-oxadiazolil-fenoxialquilisoxazolas y su uso como agentes antivirales
ES2010089A6 (es) Procedimiento para la obtencion de n-oxidos de gamma-carbolina antipsicoticos.
DK123685A (da) Analogifremgangsmaade til fremstilling af oxadiazolylimidazo-(1,4)-benzodiazepinderivater
MX9203518A (es) 9-amino-2-fenilbiciclo [3.3.1] nonanos y 9-amino-2-fenilbiciclo [3.3.1] non-2-enos y drogas que los contienen.
DE3362723D1 (en) Pyrido-triazoloquinazolines, their preparation and use
GB2020282A (en) 5,6-Dihydro-5-thioxopyrazolo [1,5-c]quinazoline derivatives
GB2013656A (en) 3-alkoxycarbonyl- benzodiazepines

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: A/S FERROSAN