FI831998A0 - Foerfarande foer framstaellning av farmaceutiskt aktiva pyrazinonderivat - Google Patents

Foerfarande foer framstaellning av farmaceutiskt aktiva pyrazinonderivat

Info

Publication number
FI831998A0
FI831998A0 FI831998A FI831998A FI831998A0 FI 831998 A0 FI831998 A0 FI 831998A0 FI 831998 A FI831998 A FI 831998A FI 831998 A FI831998 A FI 831998A FI 831998 A0 FI831998 A0 FI 831998A0
Authority
FI
Finland
Prior art keywords
pyrazinonderivat
farming
framework
pharmaceutical active
pharmaceutical
Prior art date
Application number
FI831998A
Other languages
English (en)
Other versions
FI831998L (fi
Inventor
John Colin Emmett
William John Coates
Robert Antony Slater
Brian Herbert Warrington
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838300476A external-priority patent/GB8300476D0/en
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of FI831998A0 publication Critical patent/FI831998A0/fi
Publication of FI831998L publication Critical patent/FI831998L/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/18Oxygen or sulfur atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI831998A 1982-06-05 1983-06-03 Foerfarande foer framstaellning av farmaceutiskt aktiva pyrazinonderivat FI831998L (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8216437 1982-06-05
GB838300476A GB8300476D0 (en) 1983-01-08 1983-01-08 Heterocyclic compounds

Publications (2)

Publication Number Publication Date
FI831998A0 true FI831998A0 (fi) 1983-06-03
FI831998L FI831998L (fi) 1983-12-06

Family

ID=26283037

Family Applications (1)

Application Number Title Priority Date Filing Date
FI831998A FI831998L (fi) 1982-06-05 1983-06-03 Foerfarande foer framstaellning av farmaceutiskt aktiva pyrazinonderivat

Country Status (15)

Country Link
US (2) US4556711A (fi)
EP (1) EP0096517A3 (fi)
KR (1) KR840005111A (fi)
AU (1) AU1527583A (fi)
DD (1) DD209818A5 (fi)
DK (1) DK247783A (fi)
ES (2) ES522962A0 (fi)
FI (1) FI831998L (fi)
GR (1) GR79299B (fi)
JO (1) JO1255B1 (fi)
NO (1) NO832016L (fi)
PL (1) PL242354A1 (fi)
PT (1) PT76791B (fi)
RO (1) RO86851B (fi)
ZW (1) ZW12783A1 (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4657906A (en) * 1982-06-05 1987-04-14 Smith Kline & French Laboratories Ltd. Heterocyclic compounds having inotropic activity
GB8332313D0 (en) * 1983-12-02 1984-01-11 Smith Kline French Lab Chemical compounds
US4595766A (en) * 1984-10-26 1986-06-17 Ciba-Geigy Corporation Process for the preparation of an indoline carboxylic acid
US4697016A (en) * 1984-10-26 1987-09-29 Ciba-Geigy Corporation Intermediates for the preparation of a carboxylic acid
JPS62198671A (ja) * 1986-02-25 1987-09-02 Toyo Jozo Co Ltd 1−置換アルキル1,2−ジヒドロ−2−ピラジノン誘導体
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US7879802B2 (en) 2007-06-04 2011-02-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US20100120694A1 (en) 2008-06-04 2010-05-13 Synergy Pharmaceuticals, Inc. Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
EP2321341B1 (en) 2008-07-16 2017-02-22 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
CN102470127A (zh) * 2009-08-19 2012-05-23 埃姆比特生物科学公司 联芳基化合物和其使用方法
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
MX357121B (es) 2011-03-01 2018-06-27 Synergy Pharmaceuticals Inc Star Proceso de preparacion de agonistas c de guanilato ciclasa.
EP2858982A4 (en) * 2012-06-12 2015-11-11 Abbvie Inc PYRIDINONE AND PYRIDAZINONE DERIVATIVES
CA2902348C (en) 2013-02-25 2021-11-30 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
BR112015030326A2 (pt) 2013-06-05 2017-08-29 Synergy Pharmaceuticals Inc Agonistas ultrapuros de guanilato ciclase c, método de fabricar e usar os mesmos
WO2015021358A2 (en) 2013-08-09 2015-02-12 Dominique Charmot Compounds and methods for inhibiting phosphate transport
US20200368223A1 (en) 2019-05-21 2020-11-26 Ardelyx, Inc. Methods for inhibiting phosphate transport

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3745161A (en) * 1970-04-20 1973-07-10 Merck & Co Inc Phenyl-hydroxy-pyrazine carboxylic acids and derivatives

Also Published As

Publication number Publication date
ES8500244A1 (es) 1984-10-01
RO86851A (ro) 1985-05-20
NO832016L (no) 1983-12-06
PT76791B (en) 1986-01-24
ES530024A0 (es) 1985-12-01
PT76791A (en) 1983-07-01
EP0096517A2 (en) 1983-12-21
DK247783D0 (da) 1983-06-01
DD209818A5 (de) 1984-05-23
ZW12783A1 (en) 1983-08-24
EP0096517A3 (en) 1985-04-03
JO1255B1 (en) 1985-04-20
AU1527583A (en) 1983-12-08
ES8707507A1 (es) 1985-12-01
FI831998L (fi) 1983-12-06
US4556711A (en) 1985-12-03
DK247783A (da) 1983-12-06
KR840005111A (ko) 1984-11-03
ES522962A0 (es) 1984-10-01
GR79299B (fi) 1984-10-22
PL242354A1 (en) 1984-12-17
RO86851B (ro) 1985-05-31
US4514568A (en) 1985-04-30

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Legal Events

Date Code Title Description
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Owner name: SMITH KLINE & FRENCH LABORATORIES