FI782994A - Foerfarande foer framstaellning av nya piperazinopyrrolobensodiazepiner - Google Patents

Foerfarande foer framstaellning av nya piperazinopyrrolobensodiazepiner

Info

Publication number
FI782994A
FI782994A FI782994A FI782994A FI782994A FI 782994 A FI782994 A FI 782994A FI 782994 A FI782994 A FI 782994A FI 782994 A FI782994 A FI 782994A FI 782994 A FI782994 A FI 782994A
Authority
FI
Finland
Prior art keywords
piperazinopyrrolobensodiazepiner
nya
framstaellning
framework
piperazinopyrrolobensodiazepiner framstaellning
Prior art date
Application number
FI782994A
Other languages
English (en)
Other versions
FI63578C (fi
FI63578B (fi
Inventor
Jan W F Wasley
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI782994A publication Critical patent/FI782994A/fi
Application granted granted Critical
Publication of FI63578B publication Critical patent/FI63578B/fi
Publication of FI63578C publication Critical patent/FI63578C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333—Radicals substituted by oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI782994A 1977-10-05 1978-10-02 Analogifoerfarande foer framstaellning av nya farmakologiskt verksamma 1,3,4,14b-tetrahydro-2h 10h-pyrazino(1,2-a)pyrrolo(2,1-c)(1,4)bensodiazepiner FI63578C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83969677A 1977-10-05 1977-10-05
US83969677 1977-10-05

Publications (3)

Publication Number Publication Date
FI782994A true FI782994A (fi) 1979-04-06
FI63578B FI63578B (fi) 1983-03-31
FI63578C FI63578C (fi) 1983-07-11

Family

ID=25280422

Family Applications (1)

Application Number Title Priority Date Filing Date
FI782994A FI63578C (fi) 1977-10-05 1978-10-02 Analogifoerfarande foer framstaellning av nya farmakologiskt verksamma 1,3,4,14b-tetrahydro-2h 10h-pyrazino(1,2-a)pyrrolo(2,1-c)(1,4)bensodiazepiner

Country Status (18)

Country Link
EP (1) EP0001585B1 (fi)
JP (1) JPS5461199A (fi)
AT (1) AT368157B (fi)
AU (1) AU521335B2 (fi)
CA (1) CA1113934A (fi)
DD (1) DD138774A5 (fi)
DE (1) DE2860861D1 (fi)
DK (1) DK441278A (fi)
ES (1) ES473900A1 (fi)
FI (1) FI63578C (fi)
HK (1) HK2185A (fi)
HU (1) HU179948B (fi)
IE (1) IE47390B1 (fi)
IL (1) IL55664A (fi)
NO (1) NO150159C (fi)
NZ (1) NZ188580A (fi)
SG (1) SG38684G (fi)
ZA (2) ZA784475B (fi)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4737496A (en) * 1986-10-01 1988-04-12 Ciba-Geigy Corporation 1,3,4,16b-tetrahydro-2H,10H-indolo[2,1-c]pyrazino-[1,2-a][1,4]benzodiazepines useful as serotonin-2 receptor antagonists
CA2026925A1 (en) * 1989-10-05 1991-04-06 Hiroshi Fukumi Tetracyclic compounds having anti-allergic and anti-asthmatic activities, their preparation and use
EP0539164A1 (en) * 1991-10-23 1993-04-28 Sankyo Company Limited Nitrogen-containing tetracyclic compounds having anti-allergic and anti-asthmatic activities, their preparation and use
AUPP433398A0 (en) * 1998-06-25 1998-07-16 Australian National University, The Compounds and processes

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3763183A (en) * 1972-07-10 1973-10-02 Sterling Drug Inc 1,2,3,10,11,11a-hexahydro-5h-pyrrolo (2,1-c)(1,4)benzodiazepines
US3985732A (en) * 1974-04-26 1976-10-12 American Cyanamid Company 1,2,3,11A-Tetrahydro-10-methyl-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5,11(10H)-diones
US3984562A (en) * 1975-02-24 1976-10-05 American Cyanamid Company Substituted benzodiazepines and method of use
US4017492A (en) * 1976-04-02 1977-04-12 The Upjohn Company As-triazinobenzodiazepin-1-ones
US4073784A (en) * 1977-03-09 1978-02-14 The Upjohn Company Certain as-triazino 4,3-a! 1,4!benzodiazepine-1,2-dione compounds

Also Published As

Publication number Publication date
AU4040178A (en) 1980-04-17
JPS5461199A (en) 1979-05-17
IE47390B1 (en) 1984-03-07
NO150159B (no) 1984-05-21
IE781985L (en) 1979-04-05
IL55664A0 (en) 1978-12-17
IL55664A (en) 1982-02-28
ES473900A1 (es) 1979-04-16
NZ188580A (en) 1981-12-15
AT368157B (de) 1982-09-27
FI63578C (fi) 1983-07-11
HU179948B (en) 1983-01-28
DD138774A5 (de) 1979-11-21
FI63578B (fi) 1983-03-31
CA1113934A (en) 1981-12-08
ZA785599B (en) 1979-09-26
SG38684G (en) 1985-03-29
DK441278A (da) 1979-04-06
AU521335B2 (en) 1982-03-25
EP0001585A1 (de) 1979-05-02
EP0001585B1 (de) 1981-07-22
DE2860861D1 (en) 1981-10-29
NO150159C (no) 1984-08-29
HK2185A (en) 1985-01-18
ATA715178A (de) 1982-01-15
NO783360L (no) 1979-04-06
ZA784475B (en) 1979-07-25

Similar Documents

Publication Publication Date Title
FI781811A (fi) Nya carbostyrilderivat
FI782931A (fi) Nya aemnessammansaettningar
FI782907A (fi) Nya cyklopeptider
FI780589A (fi) Nya 4-acylamino-fenyl-etanolaminer
FI781933A (fi) Nya peptidderivat
FI782157A (fi) Foerfarande foer framstaellning av nya 1-asyl-2-cyanaziridiner
FI783325A (fi) Nya derivat av kinazolin
FI782481A (fi) Foerfarande foer framstaellning av nya organiska foereningar
FI803547L (fi) Foerfaranden foer framstaellning av nya piperidylbensimidazolinoner
FI781461A (fi) Foerfarande foer framstaellning av nya alkylendiaminderivat
SE7811457L (sv) Nya kinolylguanidinderivat
FI773717A (fi) Nya aminoalkoxifenylderivater
FI783846A (fi) Nya bredspektriga cefalosporinantibioter
FI781674A (fi) Nya fluoriderade aminosyror
SE7810050L (sv) Nya 7-azabensimidazoler
FI781779A (fi) Foerfarande foer framstaellning av nya nitroso-urinaemnen
FI782228A (fi) Foerfarande foer framstaellning av nya bensopyranderivat
FI782011A (fi) Nya imidazo-isokinolin-dioner
FI782039A (fi) Nya 2-pyridyl- och 2-pyrimidylaminobensoesyror
FI782574A (fi) Foerfarande foer framstaellning av n-substituerade 2-hydrazonopropionsyraderivat
FI780444A (fi) Foerfarande foer framstaellning av nya oximderivat av 3-tiadiazolyltiometyl-7-aminotiazolacetamido-cefalosporansyra
FI781515A (fi) Foerfarande foer framstaellning av azacyklylfoereningar
SE7804318L (sv) Nya naftyridiner
FI784017A (fi) Foerfarande foer framstaellning av nya arylaminoimidazolinderivater
FI781886A (fi) Foerfarande foer framstaellning av nya pyridazinylhydrazoner

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: CIBA-GEIGY AG