FI118601B - Menetelmä terapeuttisesti käyttökelpoisen amyliiniagonistianalogin tai sen suolan valmistamiseksi - Google Patents

Menetelmä terapeuttisesti käyttökelpoisen amyliiniagonistianalogin tai sen suolan valmistamiseksi Download PDF

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Publication number
FI118601B
FI118601B FI933252A FI933252A FI118601B FI 118601 B FI118601 B FI 118601B FI 933252 A FI933252 A FI 933252A FI 933252 A FI933252 A FI 933252A FI 118601 B FI118601 B FI 118601B
Authority
FI
Finland
Prior art keywords
amylin
analog
prepared
amylinagonist
pro
Prior art date
Application number
FI933252A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI933252A (fi
FI933252A0 (fi
Inventor
Howard Jones
Laura S L Gaeta
Elisabeth Albrecht
Original Assignee
Amylin Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amylin Pharmaceuticals Inc filed Critical Amylin Pharmaceuticals Inc
Publication of FI933252A0 publication Critical patent/FI933252A0/fi
Publication of FI933252A publication Critical patent/FI933252A/fi
Application granted granted Critical
Publication of FI118601B publication Critical patent/FI118601B/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI933252A 1991-11-19 1993-07-16 Menetelmä terapeuttisesti käyttökelpoisen amyliiniagonistianalogin tai sen suolan valmistamiseksi FI118601B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US79426691A 1991-11-19 1991-11-19
US79426691 1991-11-19
US9209842 1992-11-19
PCT/US1992/009842 WO1993010146A1 (fr) 1991-11-19 1992-11-19 Peptides a action agoniste a base d'amyline et utilisations de ces peptides

Publications (3)

Publication Number Publication Date
FI933252A0 FI933252A0 (fi) 1993-07-16
FI933252A FI933252A (fi) 1993-08-23
FI118601B true FI118601B (fi) 2008-01-15

Family

ID=25162163

Family Applications (1)

Application Number Title Priority Date Filing Date
FI933252A FI118601B (fi) 1991-11-19 1993-07-16 Menetelmä terapeuttisesti käyttökelpoisen amyliiniagonistianalogin tai sen suolan valmistamiseksi

Country Status (17)

Country Link
EP (2) EP1162207A1 (fr)
JP (4) JP2902115B2 (fr)
AT (1) ATE205854T1 (fr)
AU (1) AU714439B2 (fr)
CA (1) CA2100745C (fr)
CZ (1) CZ288029B6 (fr)
DE (1) DE69232064T2 (fr)
DK (1) DK0567626T3 (fr)
ES (1) ES2161697T3 (fr)
FI (1) FI118601B (fr)
GR (1) GR3036794T3 (fr)
HK (1) HK1041891A1 (fr)
MD (1) MD960317A (fr)
NO (2) NO324405B1 (fr)
RU (1) RU2130463C1 (fr)
SK (1) SK88793A3 (fr)
WO (1) WO1993010146A1 (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU222249B1 (hu) 1991-03-08 2003-05-28 Amylin Pharmaceuticals Inc. Eljárás amilin agonista peptidszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására
US5625032A (en) * 1993-07-21 1997-04-29 Amylin Pharmaceuticals, Inc. Selective amylin antagonist peptides and uses therefor
DE69426304T2 (de) 1993-09-07 2001-03-15 Amylin Pharmaceuticals Inc Methoden zur regulation der den magen und darm betreffenden motilitaet
US6143718A (en) * 1995-06-07 2000-11-07 Amylin Pharmaceuticals, Inc. Treatment of Type II diabetes mellutis with amylin agonists
US5739106A (en) * 1995-06-07 1998-04-14 Rink; Timothy J. Appetite regulating compositions
US7312196B2 (en) 1997-01-08 2007-12-25 Amylin Pharmaceuticals, Inc. Formulations for amylin agonist peptides
US6410511B2 (en) 1997-01-08 2002-06-25 Amylin Pharmaceuticals, Inc. Formulations for amylin agonist peptides
US7101853B2 (en) * 1997-05-06 2006-09-05 Amylin Pharmaceuticals, Inc. Method for treating or preventing gastritis using amylin or amylin agonists
US7910548B2 (en) 1997-06-06 2011-03-22 Amylin Pharmaceuticals, Inc. Methods for treating obesity
ATE410182T1 (de) * 1998-01-09 2008-10-15 Amylin Pharmaceuticals Inc Formulierungen für amylin peptidagonisten mit insulin
GB0128583D0 (en) 2001-11-28 2002-01-23 Rsr Ltd Detection of autoantibodies indicative of diabetes
WO2004037168A2 (fr) 2002-10-18 2004-05-06 Amylin Pharmaceuticals, Inc. Traitement de la pancreatite avec de l'amyline
WO2004083243A1 (fr) * 2003-03-18 2004-09-30 Applied Research Systems Ars Holding N.V. Inhibiteurs d'agregation d'amyline et utilisation desdits inhibiteurs.
EP1807442A1 (fr) * 2004-10-26 2007-07-18 Lonza Ag Groupements protecteurs s-alkyl-sulphenyl pour synthese en phase solide
US8394765B2 (en) 2004-11-01 2013-03-12 Amylin Pharmaceuticals Llc Methods of treating obesity with two different anti-obesity agents
EP2286838A3 (fr) 2004-11-01 2013-09-04 Amylin Pharmaceuticals, LLC Traitement de l'obésité et de maladies liés à l'obésité
EA013121B1 (ru) 2005-03-31 2010-02-26 Амилин Фармасьютикалз, Инк. Амилин и агонисты амилина для лечения психиатрических заболеваний и расстройств
US8168592B2 (en) 2005-10-21 2012-05-01 Amgen Inc. CGRP peptide antagonists and conjugates
JP2010502670A (ja) 2006-09-07 2010-01-28 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 真性糖尿病のための組合せ治療
EP2120985B1 (fr) 2007-02-05 2012-06-27 Amylin Pharmaceuticals, Inc. FN-38 peptides pour son utilisation dans le traitement des maladies psychotiques et des troubles anxieux
JP2009149684A (ja) * 2009-03-11 2009-07-09 Amylin Pharmaceut Inc アミリン作動薬ペプチド用製剤
KR101673042B1 (ko) 2009-03-12 2016-11-04 키바이오사이언스 아게 당뇨병 및 대사 증후군의 치료
AR097701A1 (es) * 2013-09-19 2016-04-13 Zealand Pharma As Análogos de amilina
CA2928725A1 (fr) 2013-11-05 2015-05-14 Esther Priel Composes pour le traitement du diabete et des complications pathologiques qui en resultent
DK3137494T3 (da) * 2014-05-02 2021-10-04 Univ New York State Res Found Isletamyloidpolypeptider med forbedret opløselighed
EA035791B1 (ru) 2015-03-18 2020-08-11 Зилэнд Фарма А/С Аналоги амилина
US10071140B2 (en) 2016-09-09 2018-09-11 Zealand Pharma A/S Amylin analogues
WO2018144671A1 (fr) 2017-02-01 2018-08-09 The Research Foundation For The State University Of New York Polypeptides à îlots amyloïdes mutants présentant une solubilité améliorée et leurs procédés d'utilisation
KR102130354B1 (ko) * 2019-08-14 2020-07-06 엘아이지넥스원 주식회사 코어 제거용 이형장치
AU2023278353A1 (en) 2022-05-30 2024-05-23 Zealand Pharma A/S Liquid formulations of amylin analogues
WO2024061919A1 (fr) 2022-09-19 2024-03-28 Zealand Pharma A/S Polythérapie

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8720115D0 (en) * 1987-08-26 1987-09-30 Cooper G J S Treatment of diabetes mellitus
WO1989006135A1 (fr) * 1988-01-11 1989-07-13 Amylin Corporation Traitement du diabete sucre du type 2
WO1991000737A1 (fr) * 1989-07-10 1991-01-24 Amylin Corporation Traitement de l'obesite et de l'hypertension essentielle ainsi que des troubles associes
US5234906A (en) * 1991-01-10 1993-08-10 Amylin Pharmaceuticals, Inc. Hyperglycemic compositions
WO1992015317A1 (fr) * 1991-03-08 1992-09-17 Amylin Pharmaceuticals, Inc. Preparation synthetique d'amyline et d'analogues d'amyline

Also Published As

Publication number Publication date
CZ168993A3 (en) 1994-04-13
CA2100745C (fr) 2007-07-31
HK1041891A1 (zh) 2002-07-26
EP0567626A1 (fr) 1993-11-03
JP2003238594A (ja) 2003-08-27
DE69232064D1 (de) 2001-10-25
DK0567626T3 (da) 2001-12-17
NO932603D0 (no) 1993-07-19
JP2006213716A (ja) 2006-08-17
JP2902115B2 (ja) 1999-06-07
NO324405B1 (no) 2007-10-08
JPH06504794A (ja) 1994-06-02
AU1245697A (en) 1997-03-27
ATE205854T1 (de) 2001-10-15
ES2161697T3 (es) 2001-12-16
AU3075392A (en) 1993-06-15
EP1162207A1 (fr) 2001-12-12
GR3036794T3 (en) 2002-01-31
CA2100745A1 (fr) 1993-05-20
JPH11152299A (ja) 1999-06-08
NO20073265L (no) 1993-09-17
FI933252A (fi) 1993-08-23
RU2130463C1 (ru) 1999-05-20
AU714439B2 (en) 2000-01-06
FI933252A0 (fi) 1993-07-16
WO1993010146A1 (fr) 1993-05-27
JP4018116B2 (ja) 2007-12-05
CZ288029B6 (cs) 2001-04-11
MD960317A (ro) 1998-05-31
SK88793A3 (en) 1994-12-07
DE69232064T2 (de) 2002-03-28
NO932603L (no) 1993-09-17
EP0567626B1 (fr) 2001-09-19
AU673147B2 (en) 1996-10-31

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