ES8704970A1 - Procedimiento para preparar acidos corticosteroide-21-fosforicos. - Google Patents

Procedimiento para preparar acidos corticosteroide-21-fosforicos.

Info

Publication number
ES8704970A1
ES8704970A1 ES548569A ES548569A ES8704970A1 ES 8704970 A1 ES8704970 A1 ES 8704970A1 ES 548569 A ES548569 A ES 548569A ES 548569 A ES548569 A ES 548569A ES 8704970 A1 ES8704970 A1 ES 8704970A1
Authority
ES
Spain
Prior art keywords
image
salts
certicusteroid
triesters
corticosteroid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES548569A
Other languages
English (en)
Other versions
ES548569A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES548569A0 publication Critical patent/ES548569A0/es
Publication of ES8704970A1 publication Critical patent/ES8704970A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR ACIDOS CORTICOSTEROIDE-21-FOSFORICOS. CONSISTE EN HACER REACCIONAR UN CORTICOSTEROIDE DE FORMULA (II) CON UN ESTER ORGANICO DE ACIDO FOSFORICO DE FORMULA (III), OBTENIENDOSE UN COMPUESTO DE FORMULA (IV) QUE POSTERIORMENTE SE SAPONIFICA EN PRESENCIA DE UN ACIDO, A TEMPERATURA DE 40JC, EN UN DISOLVENTE INERTE, O EN PRESENCIA DE UNA BASE, PARA OBTENER ACIDOS CORTICOSTEROIDE-21-FOSFORICOS DE FORMULA (I) DONDE U ES H O CH3; V ES H, OH, O O HALOGENO; W ES H U OH; E Y ES H O F. TIENE UTILIDAD EN LA PREPARACION DE COMPOSICIONES FARMACEUTICAS.
ES548569A 1984-11-08 1985-11-06 Procedimiento para preparar acidos corticosteroide-21-fosforicos. Expired ES8704970A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843440794 DE3440794A1 (de) 1984-11-08 1984-11-08 Verfahren zur herstellung von corticosteroid-21-phosphorsaeuren und deren salzen und die corticosteroid-21-phosphorsaeuretriester

Publications (2)

Publication Number Publication Date
ES548569A0 ES548569A0 (es) 1987-04-16
ES8704970A1 true ES8704970A1 (es) 1987-04-16

Family

ID=6249784

Family Applications (2)

Application Number Title Priority Date Filing Date
ES548569A Expired ES8704970A1 (es) 1984-11-08 1985-11-06 Procedimiento para preparar acidos corticosteroide-21-fosforicos.
ES554953A Expired ES8704971A1 (es) 1984-11-08 1986-05-14 Procedimiento para preparar triesteres de acido corticosteroidefosforico

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES554953A Expired ES8704971A1 (es) 1984-11-08 1986-05-14 Procedimiento para preparar triesteres de acido corticosteroidefosforico

Country Status (8)

Country Link
US (1) US4678609A (es)
EP (1) EP0181561A1 (es)
JP (1) JPS61115095A (es)
DE (1) DE3440794A1 (es)
DK (1) DK514085A (es)
ES (2) ES8704970A1 (es)
GR (1) GR852694B (es)
PT (1) PT81443B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5192755A (en) * 1986-01-15 1993-03-09 Akzo N.V. Pregnane derivatives as immunomodulators
JP2562134B2 (ja) * 1986-09-19 1996-12-11 喜徳 喜谷 新規な白金−ステロイド錯体
DE3640709A1 (de) * 1986-11-28 1988-06-09 Schering Ag Verfahren zur herstellung von 6(alpha),9(alpha)-difluor-11ss,17(alpha)-dihydroxy-16(alpha)-methyl-4-pregnen-3,20-dion und dessen derivate
US6494447B2 (en) 2000-06-13 2002-12-17 Giesecke & Devrient America, Inc. Stacker wheel control apparatus and method utilizing start-stop synchronization
WO2004017904A2 (en) * 2002-08-23 2004-03-04 The Mclean Hospital Corporation Corticosteroid conjugates and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2870177A (en) * 1954-08-04 1959-01-20 Merck & Co Inc delta4-11-oxygenated-pregnene-17alpha, 21-diol-3, 20-dione 21-phosphate and salts thereof
US3048581A (en) * 1960-04-25 1962-08-07 Olin Mathieson Acetals and ketals of 16, 17-dihydroxy steroids
US3053834A (en) * 1961-01-26 1962-09-11 Olin Mathieson 21-phosphates of steroid acetals and ketals
US3248408A (en) * 1963-07-22 1966-04-26 Merck & Co Inc Purification of steroid phosphates
GB1010031A (en) * 1963-09-24 1965-11-17 Upjohn Co Improvements in or relating to the preparation of steroids

Also Published As

Publication number Publication date
PT81443A (de) 1985-12-01
ES548569A0 (es) 1987-04-16
GR852694B (es) 1986-03-10
PT81443B (de) 1987-07-02
ES8704971A1 (es) 1987-04-16
DE3440794A1 (de) 1986-05-15
JPS61115095A (ja) 1986-06-02
US4678609A (en) 1987-07-07
DK514085A (da) 1986-05-09
DK514085D0 (da) 1985-11-07
EP0181561A1 (de) 1986-05-21
ES554953A0 (es) 1987-04-16

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