ES8507182A1 - Procedimiento para la separacion y el aislamiento del nosiheptido - Google Patents

Procedimiento para la separacion y el aislamiento del nosiheptido

Info

Publication number
ES8507182A1
ES8507182A1 ES533991A ES533991A ES8507182A1 ES 8507182 A1 ES8507182 A1 ES 8507182A1 ES 533991 A ES533991 A ES 533991A ES 533991 A ES533991 A ES 533991A ES 8507182 A1 ES8507182 A1 ES 8507182A1
Authority
ES
Spain
Prior art keywords
nosiheptide
isolation
separation
extraction
separated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES533991A
Other languages
English (en)
Other versions
ES533991A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Publication of ES533991A0 publication Critical patent/ES533991A0/es
Publication of ES8507182A1 publication Critical patent/ES8507182A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Liquid Crystal Substances (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Flanged Joints, Insulating Joints, And Other Joints (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Control Of Motors That Do Not Use Commutators (AREA)

Abstract

PROCEDIMIENTO PARA LA SEPARACION Y EL AISLAMIENTO DEL NOSIHEPTIDO.COMPRENDE: A) MEZCLAR UN DISOLVENTE CON EL MEDIO DE CULTIVO OBTENIDO POR EL CULTIVO DE UNA CEPA PRODUCTORA DE NOSIHEPTIDO DEL GENERO STREPTOMYCES; B) SEPARAR UNA PARTE INSOLUBLE QUE CONTIENE EL MICELIO DE LA MEZCLA DE A); Y C) AISLAR EL NOSIHEPTIDO POR DESTILACION DEL DISOLVENTE Y SEPARACION DEL DISOLVENTE POR CENTRIFUGACION O FILTRACION. EL DISOLVENTE UTILIZADO ES ETER CICLICO COMO TETRAHIDROFURANO Y SU VOLUMEN ES 0,5 A 5 VECES EL DEL MEDIO DEL CULTIVO. LAS CEPAS REPRODUCTORAS DE NOSIHEPTIDO SON STREPTOMYCES ACTUOSUS (NRRL 2954; ATCC 25421) Y EL MEDIO DE CULTIVO CONTIENE SALES MINERALES E HIDRATOS DE CARBONO.SE UTILIZAN COMO ANTIBIOTICOS ADYUVANTES DE LA ALIMENTACION ANIMAL.
ES533991A 1983-07-04 1984-07-04 Procedimiento para la separacion y el aislamiento del nosiheptido Expired ES8507182A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58121273A JPS6012990A (ja) 1983-07-04 1983-07-04 ノシヘプタイドの分離回収方法

Publications (2)

Publication Number Publication Date
ES533991A0 ES533991A0 (es) 1985-08-16
ES8507182A1 true ES8507182A1 (es) 1985-08-16

Family

ID=14807167

Family Applications (1)

Application Number Title Priority Date Filing Date
ES533991A Expired ES8507182A1 (es) 1983-07-04 1984-07-04 Procedimiento para la separacion y el aislamiento del nosiheptido

Country Status (8)

Country Link
US (1) US4584134A (es)
EP (1) EP0133079B1 (es)
JP (1) JPS6012990A (es)
AT (1) ATE41952T1 (es)
CA (1) CA1213884A (es)
DE (1) DE3477584D1 (es)
DK (1) DK163670C (es)
ES (1) ES8507182A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0659226B2 (ja) * 1985-06-19 1994-08-10 三菱化成株式会社 ノシヘプタイドの分離回収方法
JP2511681B2 (ja) * 1987-09-16 1996-07-03 宇部興産株式会社 高強度軽量ケイ酸カルシウム成形体及びその製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2399247A1 (fr) * 1977-08-04 1979-03-02 Rhone Poulenc Ind Antibiotique 35665 rp, sa preparation et les compositions qui les contiennent
JPS56127092A (en) * 1980-03-10 1981-10-05 Takeda Chem Ind Ltd Preparation of antibiotic substance
US4384043A (en) * 1981-09-02 1983-05-17 American Cyanamid Company Process for producing the antibiotic nosiheptide

Also Published As

Publication number Publication date
EP0133079B1 (fr) 1989-04-05
ES533991A0 (es) 1985-08-16
ATE41952T1 (de) 1989-04-15
DK163670B (da) 1992-03-23
JPS6012990A (ja) 1985-01-23
CA1213884A (fr) 1986-11-12
EP0133079A2 (fr) 1985-02-13
DE3477584D1 (en) 1989-05-11
DK326184A (da) 1985-01-05
DK326184D0 (da) 1984-07-03
US4584134A (en) 1986-04-22
EP0133079A3 (en) 1986-07-09
DK163670C (da) 1992-08-24

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20041102