ES8505917A1 - Procedimiento para preparar derivados del acido acrilico - Google Patents
Procedimiento para preparar derivados del acido acrilicoInfo
- Publication number
- ES8505917A1 ES8505917A1 ES535566A ES535566A ES8505917A1 ES 8505917 A1 ES8505917 A1 ES 8505917A1 ES 535566 A ES535566 A ES 535566A ES 535566 A ES535566 A ES 535566A ES 8505917 A1 ES8505917 A1 ES 8505917A1
- Authority
- ES
- Spain
- Prior art keywords
- oxygen
- acrylic acid
- therapeutic
- new compounds
- compositions containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEIDMIENTO PARA LA OBTENCION DE DERIVADOS DE ACIDO ACRILICO Y DE SUS SALES ALCALINAS, ALCALINOTERREAS O AMONICAS, EN LAS FORMAS ESTEREOISOMERAS POSIBLES O DE MEZCLAS, DE FORMULA (I), EN LA QUE A Y B FORMAN UN DOBLE ENLACE C-C; Y R Y RK PUEDEN SER VARIOS RADICALES.CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA RH, EN LA QUE R TIENE EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), CON ANHIDRIDO MALEICO. LA REACCION SE EFECTUA EN PRESENCIA DE CLORURO DE ALUMINIO COMO CATALIZADOR.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANTIULCEROSA, ANTISECRETORA GASTRICA Y CITOPROTECTORA.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT19249/83A IT1193615B (it) | 1983-01-24 | 1983-01-24 | Derivati dell'acido acrilico che comprendono un eterociclo contenente ossigeno quali medicinali,prodotti industriali e procedimento di preparazione |
IT22647/83A IT1169782B (it) | 1983-08-25 | 1983-08-25 | Derivati dell'acido acrilico che contengono un ciclo ossazolico oppure isossazolico, loro procedimento di preparazione e loro applicazione come farmaco |
Publications (2)
Publication Number | Publication Date |
---|---|
ES535566A0 ES535566A0 (es) | 1985-06-16 |
ES8505917A1 true ES8505917A1 (es) | 1985-06-16 |
Family
ID=26327109
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES529073A Expired ES8507560A1 (es) | 1983-01-24 | 1984-01-23 | Procedimiento para preparar derivados del acido acrilico |
ES535566A Expired ES8505917A1 (es) | 1983-01-24 | 1984-08-31 | Procedimiento para preparar derivados del acido acrilico |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES529073A Expired ES8507560A1 (es) | 1983-01-24 | 1984-01-23 | Procedimiento para preparar derivados del acido acrilico |
Country Status (12)
Country | Link |
---|---|
US (2) | US4694019A (es) |
CA (1) | CA1244040A (es) |
CH (1) | CH661510A5 (es) |
DE (1) | DE3402313A1 (es) |
ES (2) | ES8507560A1 (es) |
FI (1) | FI81793C (es) |
FR (1) | FR2546888B1 (es) |
GB (1) | GB2139216B (es) |
HU (1) | HU187982B (es) |
LU (1) | LU85178A1 (es) |
NL (1) | NL8400217A (es) |
SE (1) | SE454355B (es) |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB532822A (en) * | 1939-08-11 | 1941-01-31 | John David Kendall | Improvements in and relating to the production of ª‡-coumarilyl and ª‡-thionaphthenoyl-acetic acid esters |
GB588108A (en) * | 1944-10-23 | 1947-05-14 | Roche Products Ltd | Manufacture of bacteriostatic substances |
US2532579A (en) * | 1946-08-06 | 1950-12-05 | Du Pont | Pest control compositions containing beta-acyl acrylates |
US2562208A (en) * | 1947-04-14 | 1951-07-31 | Schering Corp | Fungistatic composition |
DE1282644B (de) * | 1962-09-08 | 1968-11-14 | Hoechst Ag | Verfahren zur Herstellung von ungesaettigten ª€-Ketocarbonsaeureestern |
NL6717403A (es) * | 1966-12-30 | 1968-07-01 | ||
GR37790B (el) * | 1966-12-30 | 1969-07-15 | F. Hoffmann - La Roche & Co. Aktiengesellschaft | Μεθοδος δια την παρασκευην παραγωγων του αρουλακρυλικου οξεος. |
DE2047806A1 (en) * | 1970-09-29 | 1972-04-06 | Dr Karl Thomae GmbH, 7950 Biberach | 3-aroyl-acrylic acids - pharmaceutical intermediates prepd from acetophenones and glyoxylic acid derivs |
DE2103749A1 (en) * | 1971-01-27 | 1972-08-10 | Dr. Karl Thomae GmbH, 7951 Biberach | 3-acyl-acrylic acids prepn - from a ketone and glyoxylic acid (deriv) |
DE2116293A1 (de) * | 1971-04-02 | 1972-10-19 | Cassella Farbwerke Mainkur Ag, 6000 Frankfurt | Ketonderivate und Verfahren zu ihrer Herstellung |
US3753997A (en) * | 1971-06-07 | 1973-08-21 | A Ash | Trifluoromethly substituted-2,6-diphenyl-4-pyridyl carbinolamine antimalarials |
BE788749A (fr) * | 1971-09-13 | 1973-03-13 | Takeda Chemical Industries Ltd | Acide 3-(benzoyl trisubstitue)-propionique et son procede de preparation |
US4017517A (en) * | 1971-09-13 | 1977-04-12 | Takeda Chemical Industries, Ltd. | 2-(Trisubstituted benzoyl)-propionic acid and a method for the production thereof |
BE795893A (fr) * | 1972-02-28 | 1973-06-18 | Unicler | Derives de (methylene dioxy-3,4 phenyl)-1 dimethyl-4,4 pentene-1, leur preparation et leur application en therrapeutique |
CH591415A5 (en) * | 1972-09-13 | 1977-09-15 | Takeda Chemical Industries Ltd | 3-(Tri-substd. benzoyl) propionic acids - as relaxants or spasmolytics for the gall bladder |
GB1392100A (en) * | 1972-09-13 | 1975-04-23 | Beecham Group Ltd | Insecticides |
FR2270856B1 (es) * | 1974-01-17 | 1978-07-21 | Screen | |
US3953463A (en) * | 1974-03-06 | 1976-04-27 | The United States Of America As Represented By The Secretary Of The Army | 2-Aryl-6-trifluoromethyl-4-pyridyl-carbinolamine antimalarials |
US3940404A (en) * | 1974-03-06 | 1976-02-24 | The United States Of America As Represented By The Secretary Of The Army | 2-Substituted phenyl-6-trifluoromethyl-4-pyridyl-carbinolamines |
JPS5536434A (en) * | 1978-09-07 | 1980-03-14 | Sankyo Co Ltd | 4-phenyl-4-oxo-2-butenoic acid derivative and its preparation |
CA1156236A (en) * | 1979-10-25 | 1983-11-01 | George C. Rovnyak | Mercaptoacyldihydropyrazole carboxylic acid derivatives |
FR2481118A1 (fr) * | 1980-04-24 | 1981-10-30 | Roussel Uclaf | Application a titre de medicaments de derives substitues de l'acide phenyl-4-oxo-2-butenoique |
IT1171604B (it) * | 1981-10-22 | 1987-06-10 | Roussel Maestretti Spa | Derivati di acido 4-fenil-4-ossobuten-2-oico dotati di proprieta' farmacologiche e loro procedimento di preparazione |
-
1983
- 1983-12-13 SE SE8306884A patent/SE454355B/sv not_active IP Right Cessation
-
1984
- 1984-01-19 FR FR8400797A patent/FR2546888B1/fr not_active Expired
- 1984-01-23 HU HU84267A patent/HU187982B/hu not_active IP Right Cessation
- 1984-01-23 CH CH285/84A patent/CH661510A5/fr not_active IP Right Cessation
- 1984-01-23 CA CA000445823A patent/CA1244040A/fr not_active Expired
- 1984-01-23 LU LU85178A patent/LU85178A1/fr unknown
- 1984-01-23 FI FI840269A patent/FI81793C/fi not_active IP Right Cessation
- 1984-01-23 ES ES529073A patent/ES8507560A1/es not_active Expired
- 1984-01-24 NL NL8400217A patent/NL8400217A/nl not_active Application Discontinuation
- 1984-01-24 GB GB08401739A patent/GB2139216B/en not_active Expired
- 1984-01-24 DE DE19843402313 patent/DE3402313A1/de not_active Ceased
- 1984-08-31 ES ES535566A patent/ES8505917A1/es not_active Expired
-
1985
- 1985-08-14 US US06/765,539 patent/US4694019A/en not_active Expired - Fee Related
-
1987
- 1987-05-22 US US07/052,972 patent/US4814348A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
LU85178A1 (fr) | 1984-10-24 |
FR2546888B1 (fr) | 1987-01-23 |
ES535566A0 (es) | 1985-06-16 |
SE454355B (sv) | 1988-04-25 |
SE8306884L (sv) | 1984-07-25 |
FI81793B (fi) | 1990-08-31 |
US4814348A (en) | 1989-03-21 |
CH661510A5 (fr) | 1987-07-31 |
ES529073A0 (es) | 1985-09-01 |
SE8306884D0 (sv) | 1983-12-13 |
DE3402313A1 (de) | 1984-07-26 |
NL8400217A (nl) | 1984-08-16 |
GB2139216B (en) | 1986-07-16 |
FR2546888A1 (fr) | 1984-12-07 |
GB8401739D0 (en) | 1984-02-29 |
HU187982B (en) | 1986-03-28 |
FI840269A (fi) | 1984-07-25 |
FI81793C (fi) | 1990-12-10 |
US4694019A (en) | 1987-09-15 |
FI840269A0 (fi) | 1984-01-23 |
GB2139216A (en) | 1984-11-07 |
ES8507560A1 (es) | 1985-09-01 |
CA1244040A (fr) | 1988-11-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Patent lapsed |
Effective date: 19960506 |