ES8504178A1 - Procedimiento para preparar 1-(1,3-dioxolan-2-ilmetil)-azoles. - Google Patents
Procedimiento para preparar 1-(1,3-dioxolan-2-ilmetil)-azoles.Info
- Publication number
- ES8504178A1 ES8504178A1 ES530390A ES530390A ES8504178A1 ES 8504178 A1 ES8504178 A1 ES 8504178A1 ES 530390 A ES530390 A ES 530390A ES 530390 A ES530390 A ES 530390A ES 8504178 A1 ES8504178 A1 ES 8504178A1
- Authority
- ES
- Spain
- Prior art keywords
- dioxolan
- azoles
- ylmethyl
- salts
- processes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/10—Quaternary compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR 1-(1,3-DIOXOLAN-2-ILMETIL)-AZOLES.CONSISTE EN HACER REACCIONAR A UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), EN UN DISOLVENTE ORGANICO INERTE COMO N,N-DIMETILFORMAMIDA, N,N-DIMETILACEMIDA Y OTROS, EN PRESENCIA DE BASES ALCALINAS COMO HIDROGENO-CARBONATOS, CARBONATOS Y OTROS Y A UNA TEMPERATURA ENTRE 30 Y 150JC, PARA OBTENER LOS 1(1-3-DIOXOLAN-2-ILMETIL)-AZOLES DE FORMULA (I) Y SUS SALES DE ADICION DE ACIDOS FISIOLOGICAMENTE COMPATIBLES. SIENDO: G UN RADICAL DE FORMULA (IV); A, N O METINO; AR, NAFTILO, BIFENILO Y OTROS; D UN RADICAL DE FORMULA (V); R Y R INDEPENDIENTES ENTRE SI, H, HAL Y OTROS; R, H, ALQUILO DE C 1 A 12 Y OTROS Y E, HAL O UN RADICAL ESTER REACTIVO.SE UTILIZAN PARA COMBATIR A LOS HONGOS Y A LAS BACTERIAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3308554A DE3308554A1 (de) | 1983-03-10 | 1983-03-10 | 1-/1,3-dioxolan-2-ylmethyl)-azole, ihre salze, verfahren zu ihrer herstellung und ihre verwendung |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8504178A1 true ES8504178A1 (es) | 1985-04-01 |
ES530390A0 ES530390A0 (es) | 1985-04-01 |
Family
ID=6193097
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES530390A Granted ES530390A0 (es) | 1983-03-10 | 1984-03-08 | Procedimiento para preparar 1-(1,3-dioxolan-2-ilmetil)-azoles. |
ES539255A Granted ES539255A0 (es) | 1983-03-10 | 1984-12-31 | Procedimiento para preparar derivados de isoquinoleina |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES539255A Granted ES539255A0 (es) | 1983-03-10 | 1984-12-31 | Procedimiento para preparar derivados de isoquinoleina |
Country Status (13)
Country | Link |
---|---|
US (1) | US4717724A (es) |
EP (1) | EP0121753A3 (es) |
JP (1) | JPS59193885A (es) |
KR (1) | KR840008150A (es) |
AU (2) | AU563921B2 (es) |
DE (1) | DE3308554A1 (es) |
DK (1) | DK147684A (es) |
ES (2) | ES530390A0 (es) |
FI (1) | FI840946A (es) |
GR (1) | GR79518B (es) |
IL (1) | IL71192A0 (es) |
PT (1) | PT78220B (es) |
ZA (1) | ZA841757B (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY100575A (en) * | 1985-11-22 | 1990-12-15 | Ciba Geigy Ag | Microbicides |
US5240916A (en) * | 1989-07-27 | 1993-08-31 | Dowelanco | Naphthyridine derivatives |
GB8921304D0 (en) * | 1989-09-20 | 1989-11-08 | Wyeth John & Brother Ltd | New method of treatment and heterocyclic compounds used therein |
US4963563A (en) * | 1989-10-13 | 1990-10-16 | Abbott Laboratories | 6-substituted-1,2,3,4-tetrahydroisoquinolines |
IL96507A0 (en) * | 1989-12-08 | 1991-08-16 | Merck & Co Inc | Nitrogen-containing spirocycles and pharmaceutical compositions containing them |
HUT64676A (en) * | 1990-12-17 | 1994-02-28 | Shell Int Research | Fungicidal compositions containing isoquinoline derivatives as actvie agent and process for production of the active agents |
DE4216942A1 (de) * | 1992-05-22 | 1993-11-25 | Basf Ag | Tetrahydro- und Perhydroisochinolin-Derivate und diese enthaltende therapeutische Mittel |
FR2785286B1 (fr) * | 1998-10-06 | 2002-04-12 | Hoechst Marion Roussel Inc | Nouveaux derives de la 2-[3-phenyl-2-propenyl]-1,2,3,4- tetrahydro-isoquinoleine, leur procede de preparation et leur application comme fongicides |
AR020707A1 (es) * | 1998-10-06 | 2002-05-22 | Aventis Pharma Sa | Derivados de 2-[3-fenil-2-propenil]-1,2,3,4-tetrahidro-isoquinolina, su procedimiento de preparacion y su aplicacion como fungicidas |
FR2797873B1 (fr) * | 1999-08-26 | 2004-03-12 | Hoechst Marion Roussel Inc | Nouveaux derives de la 2-(3-phenyl-2-propenyl)-1,2,3,4-tetra hydro-isoquinoleine, leur procede de preparation et leur application comme fongicides |
FR2807434B1 (fr) * | 2000-04-05 | 2002-10-18 | Hoechst Marion Roussel Inc | Nouveaux derives de la 1,2,3,4-tetrahydroisoquinoleine, leur procede de preparation et leur application comme fongicides |
FR2824324B1 (fr) | 2001-05-04 | 2003-08-15 | Aventis Pharma Sa | Nouveaux derives d'azole ou de triazole, leur procede de preparation et leur application comme medicaments anti-fongiques |
FR2824325B1 (fr) * | 2001-05-04 | 2003-08-15 | Aventis Pharma Sa | Nouveaux derives d'azole ou de triazole, leur procede de preparation et leur application comme fongicides |
FR2827283B1 (fr) * | 2001-07-13 | 2003-11-28 | Aventis Pharma Sa | Nouveaux derives d'azole ou de triazole, leur procede de preparation et leur application comme fongicides |
BRPI0714622A2 (pt) * | 2006-08-04 | 2013-04-30 | Merz Pharma Gmbh & Co Kgaa | pirazolopirimidinas substituÍdas, processo para sua preparaÇço e seu uso como medicamento |
GB0706072D0 (en) * | 2007-03-28 | 2007-05-09 | Sterix Ltd | Compound |
WO2017201683A1 (en) * | 2016-05-25 | 2017-11-30 | Merck Sharp & Dohme Corp. | Substituted tetrahydroisoquinoline compounds useful as gpr120 agonists |
CN106632318B (zh) * | 2016-11-04 | 2018-07-31 | 广东环境保护工程职业学院 | 一种四氢吡啶并嘧啶类化合物及其制备方法和应用 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3583994A (en) * | 1969-03-20 | 1971-06-08 | Marion Laboratories Inc | 5-benzoyloxy-2-lower alkyl decahydroisoquinolines |
US3936470A (en) * | 1975-01-27 | 1976-02-03 | Janssen Pharmaceutica N.V. | 1,3-Dioxolan-2-ylmethylimidazoles |
US4160841A (en) * | 1977-01-31 | 1979-07-10 | Janssen Pharmaceutica, N.V. | Heterocyclic derivatives of 1-(1,3-dioxolan-2-ylmethyl)-1H-imidazoles |
US4144346A (en) * | 1977-01-31 | 1979-03-13 | Janssen Pharmaceutica N.V. | Novel 1-(1,3-dioxolan-2-ylmethyl)-1H-imidazoles |
CA1114394A (en) * | 1978-06-05 | 1981-12-15 | Paritosh M. Chakrabarti | Phosphoric acid esters of poly (2-10) ethyleneoxy n-butane 1,4 diols in synthetic aquous based metal working fluid compositions |
US4267179A (en) * | 1978-06-23 | 1981-05-12 | Janssen Pharmaceutica, N.V. | Heterocyclic derivatives of (4-phenylpiperazin-1-yl-aryloxymethyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles |
DE2967202D1 (en) * | 1978-07-03 | 1984-10-11 | Janssen Pharmaceutica Nv | Derivatives of (4-(piperazin-1-yl-phenyloxymethyl)-1.3-dioxolan-2-ylmethyl)-1h-imidazoles and -1h-1.2.4-triazoles, their preparation and use as fungicides and bactericides |
DE3039087A1 (de) * | 1980-10-16 | 1982-05-19 | Hoechst Ag, 6000 Frankfurt | 1-(1,3-dioxolan-2-ylmethyl)-azole, ihre salze, verfahren zu ihrer herstellung und ihre verwendung |
IL63918A0 (en) * | 1980-10-17 | 1981-12-31 | Pennwalt Corp | N-(amino(or hydroxy)phenethyl)-1,2,3,4-tetrahydroisoquinolines,their preparation and pharmaceutical compositions containing them |
DE3166517D1 (de) * | 1980-11-24 | 1984-11-08 | Janssen Pharmaceutica Nv | Novel (2-aryl-4-phenylthioalkyl-1,3-dioxolan-2-yl-methyl)azole derivatives |
EP0094052A3 (de) * | 1982-05-12 | 1984-07-18 | Hoechst Aktiengesellschaft | 1-(1,3-Dioxolan-2-yl-methyl)-1H-imidazole und -1H-1,2,4-triazole und deren Salze, Verfahren zu ihrer Herstellung, sie enthaltende Mittel und ihre Verwendung |
-
1983
- 1983-03-10 DE DE3308554A patent/DE3308554A1/de not_active Withdrawn
-
1984
- 1984-02-29 DK DK147684A patent/DK147684A/da not_active IP Right Cessation
- 1984-03-05 EP EP84102344A patent/EP0121753A3/de not_active Withdrawn
- 1984-03-08 FI FI840946A patent/FI840946A/fi not_active Application Discontinuation
- 1984-03-08 ES ES530390A patent/ES530390A0/es active Granted
- 1984-03-08 KR KR1019840001165A patent/KR840008150A/ko not_active Application Discontinuation
- 1984-03-08 US US06/587,585 patent/US4717724A/en not_active Expired - Fee Related
- 1984-03-08 IL IL71192A patent/IL71192A0/xx unknown
- 1984-03-09 AU AU25494/84A patent/AU563921B2/en not_active Ceased
- 1984-03-09 GR GR74052A patent/GR79518B/el unknown
- 1984-03-09 JP JP59044146A patent/JPS59193885A/ja active Pending
- 1984-03-09 PT PT78220A patent/PT78220B/pt unknown
- 1984-03-09 ZA ZA841757A patent/ZA841757B/xx unknown
- 1984-12-31 ES ES539255A patent/ES539255A0/es active Granted
-
1987
- 1987-09-03 AU AU77925/87A patent/AU7792587A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DK147684A (da) | 1984-09-11 |
PT78220B (de) | 1986-07-15 |
GR79518B (es) | 1984-10-30 |
ES8601978A1 (es) | 1985-11-16 |
AU7792587A (en) | 1987-12-10 |
US4717724A (en) | 1988-01-05 |
IL71192A0 (en) | 1984-06-29 |
EP0121753A3 (de) | 1986-11-12 |
AU563921B2 (en) | 1987-07-30 |
DE3308554A1 (de) | 1984-09-13 |
EP0121753A2 (de) | 1984-10-17 |
KR840008150A (ko) | 1984-12-13 |
FI840946A (fi) | 1984-09-11 |
JPS59193885A (ja) | 1984-11-02 |
ES530390A0 (es) | 1985-04-01 |
AU2549484A (en) | 1984-09-13 |
ZA841757B (en) | 1985-01-30 |
FI840946A0 (fi) | 1984-03-08 |
ES539255A0 (es) | 1985-11-16 |
PT78220A (de) | 1984-04-01 |
DK147684D0 (da) | 1984-02-29 |
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