ES8308211A1 - Un metodo de preparar un polvo seco que comprende un farmaco encapsulado con etilcelulosa, poli (acetato de vinilo) u otros polimeros. - Google Patents

Un metodo de preparar un polvo seco que comprende un farmaco encapsulado con etilcelulosa, poli (acetato de vinilo) u otros polimeros.

Info

Publication number
ES8308211A1
ES8308211A1 ES513202A ES513202A ES8308211A1 ES 8308211 A1 ES8308211 A1 ES 8308211A1 ES 513202 A ES513202 A ES 513202A ES 513202 A ES513202 A ES 513202A ES 8308211 A1 ES8308211 A1 ES 8308211A1
Authority
ES
Spain
Prior art keywords
pharmaceutical mixture
bad taste
concerned
pharmaceutical
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES513202A
Other languages
English (en)
Other versions
ES513202A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astra Lakemedel AB
Original Assignee
Astra Lakemedel AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Lakemedel AB filed Critical Astra Lakemedel AB
Publication of ES8308211A1 publication Critical patent/ES8308211A1/es
Publication of ES513202A0 publication Critical patent/ES513202A0/es
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

METODO PARA PREPARAR UN POLVO SECO QUE COMPRENDE UN FARMACO ENCAPSULADO CON ETILCELULOSA, POLI (ACETATO DE VINILO) U OTROS POLIMEROS, PARA OBTENER UNA PREPARACION DE MEZCLA FARMACEUTICA. SE GRANULA UNA MEZCLA DE UN AZUCAR Y 0,4 A 2% EN PESO (BASADO EN LA MEZCLA SECA) DE UNA SUBSTANCIA BASICA, Y SECAR EL GRANULADO A APROXIMADAMENTE 50 C Y SEGUIDAMENTE AÑADIR COADYUVANTES HABITUALES Y 2 A 10% EN PESO (BASADO EN LA MEZCLA SECA) DE UN FARMACO DE MAL SABOR EN UNA FORMA EN QUE EL FARMACO ES INSOLUBLE A UN PH ALTO Y ESTA ENCAPSULADO EN UNA CUBIERTA SELECCIONADA DEL GRUPO QUE CONSTA DE ETILCELULOSA, POLI (ACETATO DE VINILO), POLI (CLORURO DE VINILO) Y UN COPOLIMERO DE METACRILATO DE DIMETILAMINO ETILO Y METACRILATO DE METILO.
ES513202A 1981-06-18 1982-06-17 Un metodo de preparar un polvo seco que comprende un farmaco encapsulado con etilcelulosa, poli (acetato de vinilo) u otros polimeros. Granted ES513202A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8103843A SE8103843L (sv) 1981-06-18 1981-06-18 Farmaceutisk mixtur

Publications (2)

Publication Number Publication Date
ES8308211A1 true ES8308211A1 (es) 1983-08-16
ES513202A0 ES513202A0 (es) 1983-08-16

Family

ID=20344097

Family Applications (1)

Application Number Title Priority Date Filing Date
ES513202A Granted ES513202A0 (es) 1981-06-18 1982-06-17 Un metodo de preparar un polvo seco que comprende un farmaco encapsulado con etilcelulosa, poli (acetato de vinilo) u otros polimeros.

Country Status (18)

Country Link
US (1) US4656027A (es)
EP (1) EP0069097B1 (es)
JP (1) JPS584714A (es)
KR (1) KR880001752B1 (es)
AR (1) AR231801A1 (es)
AT (1) ATE22007T1 (es)
CA (1) CA1208559A (es)
CY (1) CY1491A (es)
DE (1) DE3273153D1 (es)
ES (1) ES513202A0 (es)
FI (1) FI80589C (es)
HK (1) HK62689A (es)
IL (1) IL65859A (es)
IS (1) IS1307B6 (es)
MY (1) MY8700297A (es)
PH (1) PH19626A (es)
SE (1) SE8103843L (es)
SG (1) SG36389G (es)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4994260A (en) * 1982-05-28 1991-02-19 Astra Lakemedel Aktiebolag Pharmaceutical mixture
SE8203953D0 (sv) * 1982-06-24 1982-06-24 Astra Laekemedel Ab Pharmaceutical mixture
NL8400911A (nl) * 1984-03-22 1985-10-16 Dagra Nv Werkwijze ter bereiding van een farmaceutische toedieningsvorm die tetracycline of doxycyclinezouten bevat.
SE8405611D0 (sv) * 1984-11-09 1984-11-09 Astra Laekemedel Ab Process for stabilization of bacampicillin hydrochloride
SE458576B (sv) * 1985-06-20 1989-04-17 Lejus Medical Ab Foerfarande foer framstaellning av en guar-gum produkt
US4971791A (en) * 1985-08-26 1990-11-20 The Procter & Gamble Company Taste masking compositions
US4764375A (en) * 1985-09-11 1988-08-16 Kv Pharmaceutical Company Sachet drug delivery system
GB8623557D0 (en) * 1986-10-01 1986-11-05 Boots Co Plc Therapeutic agents
US4800087A (en) * 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
SE8605515D0 (sv) * 1986-12-22 1986-12-22 Astra Laekemedel Ab A liquid dosage form for oral administration of a pharmaceutically active substance
US4874613A (en) * 1987-03-06 1989-10-17 Baker Cummins Pharmaceuticals, Inc. Taste concealing pharmaceutical dosage unit
US5084278A (en) * 1989-06-02 1992-01-28 Nortec Development Associates, Inc. Taste-masked pharmaceutical compositions
DE69104453T2 (de) * 1990-09-13 1995-03-16 Akzo Nv Stabilisierte feste chemische Zusammensetzungen.
US5518737A (en) * 1991-10-16 1996-05-21 Orion-Yhtyma Oy Peroral drug delivery system
JP3265680B2 (ja) * 1992-03-12 2002-03-11 大正製薬株式会社 経口製剤用組成物
US5637322A (en) * 1992-11-06 1997-06-10 Japan Tobacco Inc. Method for producing composition for solid medicine
US6117455A (en) * 1994-09-30 2000-09-12 Takeda Chemical Industries, Ltd. Sustained-release microcapsule of amorphous water-soluble pharmaceutical active agent
US5639475A (en) * 1995-02-03 1997-06-17 Eurand America, Incorporated Effervescent microcapsules
WO1996029986A1 (en) * 1995-03-29 1996-10-03 The Procter & Gamble Company Antitussive microcapsules
US5972373A (en) * 1995-05-02 1999-10-26 Taisho Pharmaceutical Co., Ltd. Taste masking pharmaceutical composition for oral administration
DE19706978A1 (de) * 1997-02-21 1998-08-27 Ulrich Dr Posanski Kombinationspräparat für oral applizierbare Antibiotika
DE19706979A1 (de) * 1997-02-21 1998-08-27 Lindopharm Gmbh Kombinationspräparat für oral applizierbare Erythromycine
GB9928343D0 (en) * 1999-11-30 2000-01-26 Vericore Ltd Addition of tetracyclines to animal foodstuffs
GB0001315D0 (en) * 2000-01-20 2000-03-08 Novartis Ag Organic compounds
ES2284643T3 (es) 2000-04-20 2007-11-16 Novartis Ag Composicion de revestimiento enmascarante del sabor.
US6551617B1 (en) 2000-04-20 2003-04-22 Bristol-Myers Squibb Company Taste masking coating composition
DK1411899T3 (da) * 2001-08-01 2009-06-02 Novartis Ag Smagsmaskerende sammensætning
CN100337630C (zh) 2002-03-12 2007-09-19 布里斯托尔-迈尔斯斯奎布公司 可口的口服悬浮液及其制备方法
US20050226926A1 (en) 2002-07-25 2005-10-13 Pfizer Inc Sustained-release tablet composition of pramipexole
AR040682A1 (es) * 2002-07-25 2005-04-13 Pharmacia Corp Forma de dosificacion una vez al dia de pramipexol
JP3821081B2 (ja) * 2002-09-30 2006-09-13 日本電気株式会社 燃料電池およびこれを搭載した携帯機器ならびに燃料電池の運転方法
US20040170686A1 (en) * 2003-01-31 2004-09-02 Fredrickson Jennifer K. Suspension vehicle for coated drug particles
US20040191326A1 (en) * 2003-03-31 2004-09-30 Reo Joseph P. Taste-masking vehicle for coated oxazolidinone particles
KR100503949B1 (ko) * 2003-04-28 2005-07-26 주식회사유한양행 염산 온단세트론의 쓴맛을 효과적으로 은폐한 경구용 구강속붕해정 조성물
CN101849921A (zh) * 2004-08-13 2010-10-06 贝林格尔·英格海姆国际有限公司 包含普拉克索或其可药用盐的延长释放片剂
JP4971159B2 (ja) * 2004-08-13 2012-07-11 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング プラミペキソール又はその薬学的に許容しうる塩を含有する徐放性ペレット製剤、その製法及び使用
RU2007127999A (ru) * 2004-12-23 2009-01-27 МакНЕЙЛ-ППС, ИНК. (US) Орально распадающееся фармацевтические композиции с сенсорными сигнальными агентами
CA2641665A1 (en) * 2006-02-10 2007-08-16 Boehringer Ingelheim International Gmbh Modified release formulation
WO2007090883A1 (en) * 2006-02-10 2007-08-16 Boehringer Ingelheim International Gmbh Extended release formulation
JP4716063B2 (ja) * 2009-09-30 2011-07-06 ライオン株式会社 不快味マスキング粒子及びこれを含有する経口製剤
CN108845065B (zh) * 2018-06-19 2021-06-22 广西壮族自治区食品药品检验所 测定磺胺嘧啶混悬液中有关物质的hplc法

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* Cited by examiner, † Cited by third party
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NL280827A (es) * 1962-07-11 1900-01-01
DE2010416B2 (de) * 1970-03-05 1979-03-29 Hoechst Ag, 6000 Frankfurt Oral anwendbare Arzneiform mit Retardwirkung
JPS4843419B1 (es) * 1970-08-07 1973-12-18
JPS541767B2 (es) * 1973-03-09 1979-01-29
JPS5840529B2 (ja) * 1975-09-29 1983-09-06 明治製菓株式会社 ケイコウヨウセイザイノセイホウ
GB1561301A (en) * 1976-01-02 1980-02-20 Beecham Group Ltd Orally administrable pharmaceutical composition
US4205060A (en) * 1978-12-20 1980-05-27 Pennwalt Corporation Microcapsules containing medicament-polymer salt having a water-insoluble polymer sheath, their production and their use
JPS5587715A (en) * 1978-12-26 1980-07-02 Yoshitomi Pharmaceut Ind Ltd Stabilization of bacanpicillin hydrochloride
JPS55129224A (en) * 1979-03-27 1980-10-06 Toyo Jozo Co Ltd Fine granules having improved taste
JPS55153715A (en) * 1979-05-18 1980-11-29 Nikken Kagaku Kk Prolonged granule of theophylline
US4321253A (en) * 1980-08-22 1982-03-23 Beatty Morgan L Suspension of microencapsulated bacampicillin acid addition salt for oral, especially pediatric, administration

Also Published As

Publication number Publication date
EP0069097A3 (en) 1983-08-10
US4656027A (en) 1987-04-07
FI80589B (fi) 1990-03-30
IL65859A (en) 1986-12-31
CA1208559A (en) 1986-07-29
FI80589C (fi) 1990-07-10
EP0069097B1 (en) 1986-09-10
JPS584714A (ja) 1983-01-11
DE3273153D1 (en) 1986-10-16
IS2730A7 (is) 1982-12-19
AR231801A1 (es) 1985-03-29
PH19626A (en) 1986-06-04
IS1307B6 (is) 1988-03-22
JPH0460968B2 (es) 1992-09-29
FI822191L (fi) 1982-12-19
SE8103843L (sv) 1982-12-19
HK62689A (en) 1989-08-11
CY1491A (en) 1990-02-16
IL65859A0 (en) 1982-08-31
SG36389G (en) 1989-10-13
KR840000228A (ko) 1984-02-18
MY8700297A (en) 1987-12-31
FI822191A0 (fi) 1982-06-17
EP0069097A2 (en) 1983-01-05
KR880001752B1 (ko) 1988-09-12
ATE22007T1 (de) 1986-09-15
ES513202A0 (es) 1983-08-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20020506