IL53094A0 - New hydantoin derivatives their preparation and pharmaceutical compositions containing them - Google Patents

New hydantoin derivatives their preparation and pharmaceutical compositions containing them

Info

Publication number: IL53094A0
Authority: IL; Israel
Prior art keywords: preparation; pharmaceutical compositions; compositions containing; hydantoin derivatives; new hydantoin
Prior art date: 1976-10-18

Application number

IL53094A

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-10-18

Filing date

1977-10-10

Publication date

1977-12-30

1977-02-11 Priority claimed from US05/767,803 external-priority patent/US4117230A/en

1977-10-10 Application filed by Pfizer filed Critical Pfizer

1977-12-30 Publication of IL53094A0 publication Critical patent/IL53094A0/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Diabetes (AREA)
Ophthalmology & Optometry (AREA)
Obesity (AREA)
Hematology (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Psychiatry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

IL53094A 1976-10-18 1977-10-10 New hydantoin derivatives their preparation and pharmaceutical compositions containing them IL53094A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US73306276A	1976-10-18	1976-10-18
US05/767,803 US4117230A (en)	1976-10-18	1977-02-11	Hydantoin derivatives as therapeutic agents

Publications (1)

Publication Number	Publication Date
IL53094A0 true IL53094A0 (en)	1977-12-30

Family

ID=27112515

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL53094A IL53094A0 (en)	1976-10-18	1977-10-10	New hydantoin derivatives their preparation and pharmaceutical compositions containing them

Country Status (29)

Country	Link
JP (3)	JPS5353653A (en)
AR (1)	AR220901A1 (en)
AT (1)	AT356136B (en)
AU (1)	AU504978B2 (en)
BG (1)	BG28847A3 (en)
CA (1)	CA1088945A (en)
CH (1)	CH625511A5 (en)
DD (1)	DD131931A5 (en)
DE (4)	DE2759542C2 (en)
DK (1)	DK150302C (en)
ES (1)	ES463267A1 (en)
FI (1)	FI62307C (en)
FR (1)	FR2367754A1 (en)
GB (1)	GB1566171A (en)
GR (1)	GR70201B (en)
HK (1)	HK53881A (en)
IE (1)	IE45805B1 (en)
IL (1)	IL53094A0 (en)
KE (1)	KE3167A (en)
LU (1)	LU78330A1 (en)
MX (1)	MX4899E (en)
MY (1)	MY8200157A (en)
NL (1)	NL167434C (en)
NO (1)	NO148453C (en)
NZ (1)	NZ185358A (en)
PH (1)	PH15639A (en)
PT (1)	PT67164B (en)
SE (1)	SE437024B (en)
YU (1)	YU40821B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4130714A (en) *	1977-05-23	1978-12-19	Pfizer Inc.	Hydantoin therapeutic agents
US4127665A (en) *	1978-01-18	1978-11-28	Pfizer Inc.	Thienohydantoin derivatives
US4147797A (en) *	1978-08-11	1979-04-03	Pfizer Inc.	Spiro-furanohydantoin derivatives
US4200642A (en) *	1978-08-21	1980-04-29	Pfizer Inc.	Spiro-oxazolidindiones
US4181728A (en) *	1978-11-16	1980-01-01	Pfizer Inc.	Spiro-polycyclicimidazolidinedione derivatives
US4181729A (en) *	1979-03-21	1980-01-01	Pfizer Inc.	Phenyl or phenoxy substituted spiro-imidazolidinedione derivatives
US4235911A (en) *	1979-06-13	1980-11-25	Pfizer Inc.	Hydantoin derivatives
US4283409A (en) *	1979-10-29	1981-08-11	Pfizer Inc.	Imidazolone derivatives
US4286098A (en) *	1980-03-28	1981-08-25	Pfizer Inc.	Process for the preparation of chiral hydantoins
JPS5745185A (en) *	1980-07-21	1982-03-13	Eisai Co Ltd	Hydantoin derivative and its preparation
DE3262294D1 (en) *	1981-05-13	1985-03-28	Ici Plc	Pharmaceutical compositions containing spiro succinimide derivatives
JPS58213717A (en) *	1982-01-20	1983-12-12	Eisai Co Ltd	Remedy containing hydantoin derivative
JPS59500617A (en) *	1982-04-15	1984-04-12	アルコン・ラボラトリ−ズ・インコ−ポレ−テッド	Hydantoin therapeutic agent
SU1380610A3 (en) *	1982-12-06	1988-03-07	Пфайзер Инк. (Фирма)	Method of producing spiroheteroazolydindiones or pharmaceutically acceptable salts thereof
US4474967A (en) *	1983-04-27	1984-10-02	Pfizer Inc.	8-Deutero and 8-tritio-substituted derivatives of D-4S-6-fluoro-spiro-[chroman-4,4'-imidazolidine]-2',5'-dione
WO1986002647A1 (en) *	1984-10-30	1986-05-09	Pfizer Inc.	Spiro-heteroazolones for treatment of diabetes complications
JPS61200991A (en) *	1985-03-04	1986-09-05	Sanwa Kagaku Kenkyusho:Kk	Novel spiro-3-heteroazolidine compound, production thereof, preventive and remedy for diabetic complication comprising same as active ingredient
US4575507A (en) *	1985-05-29	1986-03-11	Pfizer Inc.	Spiro-imidazolidines as aldose reductase inhibitors and their pharmaceutical use
JPS6357588A (en) *	1986-08-28	1988-03-12	Sanwa Kagaku Kenkyusho Co Ltd	Hydantoin derivative, salt and, production thereof and preventing and treating, agent for diabetic complication
MX12896A (en) *	1987-09-04	1993-06-01	Pfizer	PROCEDURE FOR PREPARING A SPYRO-HETEROAZOLON COMPOUND
GB2355264A (en)	1999-09-30	2001-04-18	Merck & Co Inc	Spirohydantoin derivatives useful as alpha 1a adrenoceptor antagonists
WO2003088915A2 (en)	2002-04-18	2003-10-30	University Of Virginia Patent Foundation	Novel sodium channel blockers
FR2955107B1 (en)	2010-01-08	2012-03-02	Servier Lab	NOVEL THIOCHROMAN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB818724A (en) *	1956-10-18	1959-08-19	Ici Ltd	Hydantoin derivatives
DE1135915B (en) *	1961-06-29	1962-09-06	Asta Werke Ag Chem Fab	Process for the production of new, anticonvulsant spirohydantoins
US3532744A (en) *	1967-07-28	1970-10-06	American Home Prod	1- and 2-amino substituted indane and tetralene carboxylic acids
US3821383A (en) *	1972-07-10	1974-06-28	Ayerst Mckenna & Harrison	Compositions for and a method of treating diabetic complications
DE2449030A1 (en) *	1974-10-11	1976-05-20	Schering Ag	NEW PYRIDINE DERIVATIVES
US4130714A (en) *	1977-05-23	1978-12-19	Pfizer Inc.	Hydantoin therapeutic agents

1977
- 1977-09-30 CA CA287,868A patent/CA1088945A/en not_active Expired
- 1977-10-03 SE SE7711053A patent/SE437024B/en not_active IP Right Cessation
- 1977-10-04 GR GR54503A patent/GR70201B/el unknown
- 1977-10-05 NZ NZ185358A patent/NZ185358A/en unknown
- 1977-10-06 AU AU29431/77A patent/AU504978B2/en not_active Expired
- 1977-10-10 IL IL53094A patent/IL53094A0/en not_active IP Right Cessation
- 1977-10-10 YU YU2442/77A patent/YU40821B/en unknown
- 1977-10-14 DE DE2759542A patent/DE2759542C2/de not_active Expired
- 1977-10-14 PH PH20335A patent/PH15639A/en unknown
- 1977-10-14 DE DE2746244A patent/DE2746244C2/en not_active Expired
- 1977-10-14 FI FI773060A patent/FI62307C/en not_active IP Right Cessation
- 1977-10-14 DE DE2759927A patent/DE2759927C2/en not_active Expired
- 1977-10-14 DE DE2759543A patent/DE2759543C2/de not_active Expired
- 1977-10-15 ES ES463267A patent/ES463267A1/en not_active Expired
- 1977-10-17 DK DK461377A patent/DK150302C/en not_active IP Right Cessation
- 1977-10-17 IE IE2114/77A patent/IE45805B1/en not_active IP Right Cessation
- 1977-10-17 PT PT67164A patent/PT67164B/en unknown
- 1977-10-17 FR FR7731216A patent/FR2367754A1/en active Granted
- 1977-10-17 NO NO773548A patent/NO148453C/en unknown
- 1977-10-17 CH CH1262677A patent/CH625511A5/en not_active IP Right Cessation
- 1977-10-17 NL NL7711358.A patent/NL167434C/en not_active IP Right Cessation
- 1977-10-17 GB GB43122/77A patent/GB1566171A/en not_active Expired
- 1977-10-17 MX MX776490U patent/MX4899E/en unknown
- 1977-10-17 JP JP12437177A patent/JPS5353653A/en active Granted
- 1977-10-17 LU LU78330A patent/LU78330A1/en unknown
- 1977-10-18 AT AT745977A patent/AT356136B/en not_active IP Right Cessation
- 1977-10-18 AR AR269623A patent/AR220901A1/en active
- 1977-10-18 BG BG7737604A patent/BG28847A3/en unknown
- 1977-10-18 DD DD7700201582A patent/DD131931A5/en unknown
1978
- 1978-11-25 JP JP53145926A patent/JPS607997B2/en not_active Expired
- 1978-11-25 JP JP53145925A patent/JPS5940388B2/en not_active Expired
1981
- 1981-10-09 KE KE3167A patent/KE3167A/en unknown
- 1981-11-05 HK HK538/81A patent/HK53881A/en unknown
1982
- 1982-12-30 MY MY157/82A patent/MY8200157A/en unknown

Also Published As

Publication number	Publication date
JPS5495570A (en)	1979-07-28
JPS5940388B2 (en)	1984-09-29
IE45805B1 (en)	1982-12-01
FI62307C (en)	1982-12-10
NO148453B (en)	1983-07-04
FI773060A (en)	1978-04-19
JPS5495575A (en)	1979-07-28
JPS607997B2 (en)	1985-02-28
HK53881A (en)	1981-11-13
DE2759543C2 (en)	1987-04-09
ES463267A1 (en)	1978-07-16
FR2367754B1 (en)	1982-07-09
AU2943177A (en)	1979-04-12
MX4899E (en)	1982-12-14
NL167434C (en)	1981-12-16
IE45805L (en)	1978-04-18
NL167434B (en)	1981-07-16
NL7711358A (en)	1978-04-20
PH15639A (en)	1983-03-11
YU244277A (en)	1982-08-31
SE7711053L (en)	1978-04-19
NO773548L (en)	1978-04-19
AU504978B2 (en)	1979-11-01
MY8200157A (en)	1982-12-31
FI62307B (en)	1982-08-31
DE2746244C2 (en)	1983-05-19
PT67164A (en)	1977-11-01
YU40821B (en)	1986-06-30
DE2759542C2 (en)	1988-07-07
JPS5534132B2 (en)	1980-09-04
AR220901A1 (en)	1980-12-15
DD131931A5 (en)	1978-08-09
SE437024B (en)	1985-02-04
DE2746244A1 (en)	1978-04-20
DK150302B (en)	1987-02-02
PT67164B (en)	1979-03-20
FR2367754A1 (en)	1978-05-12
LU78330A1 (en)	1979-06-01
CA1088945A (en)	1980-11-04
NZ185358A (en)	1979-06-08
JPS5353653A (en)	1978-05-16
DK150302C (en)	1987-09-28
ATA745977A (en)	1979-09-15
DK461377A (en)	1978-04-19
KE3167A (en)	1981-11-06
DE2759927C2 (en)	1986-12-04
AT356136B (en)	1980-04-10
BG28847A3 (en)	1980-07-15
CH625511A5 (en)	1981-09-30
NO148453C (en)	1983-10-12
GR70201B (en)	1982-08-31
GB1566171A (en)	1980-04-30

Legal Events

Date	Code	Title	Description
1996-08-04	RH	Patent void

Publication	Publication Date	Title
IL51660A0 (en)	1977-05-31	Hentriakontapeptides their preparation and pharmaceutical compositions containing them
IL53094A0 (en)	1977-12-30	New hydantoin derivatives their preparation and pharmaceutical compositions containing them
IL53043A (en)	1982-01-31	N-heterocyclylalkyl-(1-aryloxy-2-hydroxy-3-amino-propane)derivatives,their preparation and pharmaceutical compositions containing them
NZ184281A (en)	1980-04-28	Hydantoin derivatives and pharmaceutical compositions
IL49325A (en)	1979-11-30	8-aza-11-deoxy-pge1 derivatives,their preparation and pharmaceutical compositions containing them
IL52370A0 (en)	1977-08-31	New thienopyridine derivatives their preparation and pharmaceutical compositions containing them
IL51812A0 (en)	1977-06-30	New isothiazolopyridine derivatives their preparation and pharmaceutical compositions containing them
DE2862404D1 (en)	1984-06-20	Hydantoin derivatives, their preparation and pharmaceutical compositions containing them
IL52041A0 (en)	1977-07-31	New quinazoline derivatives their preparation and pharmaceutical compositions containing them
IL52717A (en)	1980-12-31	Derivatives of2-phenylamino-imidazoline-(2),their preparation and pharmaceutical compositions containing them
IL52857A (en)	1983-03-31	Oxo-benzopyrane derivatives,their preparation and pharmaceutical compositions containing them
NZ184102A (en)	1979-03-28	Derivatives of benzenesulphonylurea,and pharmaceutical compositions
IL52638A0 (en)	1977-10-31	Novel olivanic acid derivatives their preparation and pharmaceutical compositions containing them
IL58620A0 (en)	1980-02-29	Aryltrifluoroethanol derivatives their preparation and pharmaceutical compositions containing them
IL51998A0 (en)	1977-07-31	New benzodiazepine derivatives their preparation and pharmaceutical compositions containing them
IL53642A0 (en)	1978-03-10	New indoloquinolizine derivatives their preparation and pharmaceutical compositions containing them
IL51468A (en)	1981-01-30	17 -hydroxy- -d-homosteroid derivatives,their preparation and pharmaceutical compositions containing them
NZ185267A (en)	1979-07-11	Derivatives of 1-amino-2hydroxy-3-heterocycloxy-propanes, and pharmaceutical compositions containing them
IL53026A0 (en)	1977-11-30	New pyridobenzodiazepinones their preparation and pharmaceutical compositions containing them
IL53009A0 (en)	1977-11-30	New imidazoisoquinoline derivatives their preparation and pharmaceutical compositions containing them
IL52006A0 (en)	1977-07-31	Novel nephthalene derivatives their preparation and pharmaceutical compositions containing them
IL52962A0 (en)	1977-11-30	New perhydroindolinol derivatives their preparation and pharmaceutical compositions containing them
IL52853A0 (en)	1977-10-31	New aryl-alkylamines their preparation and pharmaceutical compositions containing them
IL51718A0 (en)	1977-05-31	Dibenzothiophene derivatives their preparation and pharmaceutical compositions containing them
IL51935A (en)	1981-07-31	Derivatives of n,3-disubstituted-2-iminothiazolidines and pharmaceutical compositions containing them