ES8306114A1 - "procedimiento para la preparacion de una sulfonilurea". - Google Patents
"procedimiento para la preparacion de una sulfonilurea".Info
- Publication number
- ES8306114A1 ES8306114A1 ES515395A ES515395A ES8306114A1 ES 8306114 A1 ES8306114 A1 ES 8306114A1 ES 515395 A ES515395 A ES 515395A ES 515395 A ES515395 A ES 515395A ES 8306114 A1 ES8306114 A1 ES 8306114A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- atoms
- pharmaceutical compositions
- compositions containing
- sulfonyl ureas
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE SULFONILUREAS Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE Y ES ALCOHILENO C <- ; R ES ALCOHILO C <- ; R ES HIDROGENO, CLORO O METILO; Y R PUEDE SER UNO DE VARIOS RADICALES. CONSISTE EN LA REACCION DE DESDOBLAMIENTO DE BENZOSULFONIL-ISOUREA-ETERES, BENZOSULFONIL-ISOTIOUREA-ETERES, ACIDOS BENZOSULFONIL-PARABANICOS O AMIDINAS DE ACIDOS BENZOSULFONIL-HALOGENOFORMICOS, SUSTITUIDOS CON EL GRUPO DE FORMULA (II), EN LA QUE Y, R Y R TIENEN EL MISMO SIGNIFICADO QUE QUE EN LA FORMULA (I). LA REACCION SE EFECTUA EN UN DISOLVENTE INERTE, EN PRESENCIA DE UNA BASE, O EN MEDIO ACIDO, A LA TEMPERATURA AMBIENTE O SUPERIOR. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SUS PROPIEDADES HIPOGLUCEMICAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19813134780 DE3134780A1 (de) | 1981-09-02 | 1981-09-02 | "sulfonylharnstoffe, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung" |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8306114A1 true ES8306114A1 (es) | 1983-05-01 |
ES515395A0 ES515395A0 (es) | 1983-05-01 |
Family
ID=6140704
Family Applications (6)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES515397A Granted ES515397A0 (es) | 1981-09-02 | 1982-08-31 | "procedimiento para la preparacion de una sulfonilurea". |
ES515399A Granted ES515399A0 (es) | 1981-09-02 | 1982-08-31 | "procedimiento para la preparacion de una sulfonilurea". |
ES515398A Expired ES8306117A1 (es) | 1981-09-02 | 1982-08-31 | "procedimiento para la preparacion de una sulfonilurea". |
ES515396A Expired ES8306115A1 (es) | 1981-09-02 | 1982-08-31 | "procedimiento para la preparacion de una sulfonilurea". |
ES515395A Granted ES515395A0 (es) | 1981-09-02 | 1982-08-31 | "procedimiento para la preparacion de una sulfonilurea". |
ES515384A Granted ES515384A0 (es) | 1981-09-02 | 1982-08-31 | "procedimiento para la preparacion de una solfonilurea". |
Family Applications Before (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES515397A Granted ES515397A0 (es) | 1981-09-02 | 1982-08-31 | "procedimiento para la preparacion de una sulfonilurea". |
ES515399A Granted ES515399A0 (es) | 1981-09-02 | 1982-08-31 | "procedimiento para la preparacion de una sulfonilurea". |
ES515398A Expired ES8306117A1 (es) | 1981-09-02 | 1982-08-31 | "procedimiento para la preparacion de una sulfonilurea". |
ES515396A Expired ES8306115A1 (es) | 1981-09-02 | 1982-08-31 | "procedimiento para la preparacion de una sulfonilurea". |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES515384A Granted ES515384A0 (es) | 1981-09-02 | 1982-08-31 | "procedimiento para la preparacion de una solfonilurea". |
Country Status (20)
Country | Link |
---|---|
US (1) | US4542139A (es) |
EP (1) | EP0073507B1 (es) |
JP (1) | JPS5846068A (es) |
KR (1) | KR880002706B1 (es) |
AT (1) | ATE16102T1 (es) |
AU (1) | AU558339B2 (es) |
CA (1) | CA1193603A (es) |
DE (2) | DE3134780A1 (es) |
DK (1) | DK391982A (es) |
ES (6) | ES515397A0 (es) |
FI (1) | FI76567C (es) |
GR (1) | GR76895B (es) |
HU (1) | HU188805B (es) |
IL (1) | IL66697A0 (es) |
MX (1) | MX154808A (es) |
NO (1) | NO822940L (es) |
NZ (1) | NZ201768A (es) |
PH (1) | PH18218A (es) |
PT (1) | PT75492B (es) |
ZA (1) | ZA826391B (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3210063A1 (de) * | 1982-03-19 | 1983-09-22 | Hoechst Ag, 6230 Frankfurt | Sulfonylharnstoffe, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung |
SE9201076L (sv) * | 1992-04-06 | 1993-10-07 | Shimon Slavin | Användningen av gamla läkemedel för behandling av diabetes |
US5681832A (en) * | 1995-02-17 | 1997-10-28 | The United States Of America As Represented By The Department Of Health And Human Services | Aroylaniline compounds, pharmaceutical compositions, and methods of using same to inhibit viral activity |
JP2000256323A (ja) | 1999-01-08 | 2000-09-19 | Japan Tobacco Inc | 2−オキソキノリン化合物及びその医薬用途 |
CA2433158C (en) | 2000-12-28 | 2011-05-10 | Shionogi & Co., Ltd. | Pyridone derivatives having a binding activity to the cannabinoid type 2 receptor |
KR101423483B1 (ko) * | 2005-11-03 | 2014-07-28 | 포톨라 파마슈티컬스, 인코포레이티드 | 〔4-(6-할로-7-치환된-2,4-디옥소-1,4-디히드로-2h-퀴나졸린-3-일)-페닐〕-5-클로로티오펜-2-일-설포닐우레아 및 이의 형태 및 이와 관련된 방법 |
US20090042916A1 (en) * | 2007-05-02 | 2009-02-12 | Portola Pharmaceuticals, Inc. | [4-(6-fluoro-7-methylamino-2,4-dioxo-1,4-dihydro-2h-quinazolin-3-yl)-phenyl]-5-chloro-thiophen-2-yl-sulfonylurea salts, forms and methods related thereto |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3819633A (en) * | 1970-04-01 | 1974-06-25 | Erba Carlo Spa | (iso)quinolyl sulfonylureas having antidiabetic activity |
DE2621958A1 (de) * | 1976-05-18 | 1977-12-08 | Hoechst Ag | Benzolsulfonylharnstoffe und verfahren zu ihrer herstellung |
AT357560B (de) * | 1976-05-18 | 1980-07-25 | Hoechst Ag | Verfahren zur herstellung von neuen (1,2- dihydro-2-oxo-nicotinamido)-alkylbenzolsul- fonylharnstoffen und von deren salzen |
MTP848B (en) * | 1978-06-27 | 1980-06-24 | Hoechst Ag | Sulfonyl ureas process for their manufacture pharmaceutical preparation on the basis of there compounds and their use |
DE2948434A1 (de) * | 1979-12-01 | 1981-06-11 | Hoechst Ag, 6000 Frankfurt | 1-piperidinsulfonylharnstoffe und verfahren zu ihrer herstellung |
DE2951135A1 (de) * | 1979-12-19 | 1981-06-25 | Hoechst Ag, 6230 Frankfurt | Sulfonylharnstoffe, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung |
-
1981
- 1981-09-02 DE DE19813134780 patent/DE3134780A1/de not_active Withdrawn
-
1982
- 1982-08-28 AT AT82107938T patent/ATE16102T1/de not_active IP Right Cessation
- 1982-08-28 EP EP82107938A patent/EP0073507B1/de not_active Expired
- 1982-08-28 DE DE8282107938T patent/DE3266953D1/de not_active Expired
- 1982-08-31 ES ES515397A patent/ES515397A0/es active Granted
- 1982-08-31 NO NO822940A patent/NO822940L/no unknown
- 1982-08-31 NZ NZ201768A patent/NZ201768A/en unknown
- 1982-08-31 FI FI823007A patent/FI76567C/fi not_active IP Right Cessation
- 1982-08-31 GR GR69173A patent/GR76895B/el unknown
- 1982-08-31 ES ES515399A patent/ES515399A0/es active Granted
- 1982-08-31 ES ES515398A patent/ES8306117A1/es not_active Expired
- 1982-08-31 KR KR8203918A patent/KR880002706B1/ko active
- 1982-08-31 ES ES515396A patent/ES8306115A1/es not_active Expired
- 1982-08-31 ES ES515395A patent/ES515395A0/es active Granted
- 1982-08-31 ES ES515384A patent/ES515384A0/es active Granted
- 1982-08-31 MX MX7875A patent/MX154808A/es unknown
- 1982-08-31 PH PH27799A patent/PH18218A/en unknown
- 1982-09-01 AU AU87892/82A patent/AU558339B2/en not_active Ceased
- 1982-09-01 ZA ZA826391A patent/ZA826391B/xx unknown
- 1982-09-01 DK DK391982A patent/DK391982A/da not_active Application Discontinuation
- 1982-09-01 HU HU822814A patent/HU188805B/hu unknown
- 1982-09-01 PT PT75492A patent/PT75492B/pt unknown
- 1982-09-01 IL IL66697A patent/IL66697A0/xx unknown
- 1982-09-01 JP JP57150810A patent/JPS5846068A/ja active Pending
- 1982-09-01 CA CA000410586A patent/CA1193603A/en not_active Expired
-
1984
- 1984-04-26 US US06/603,987 patent/US4542139A/en not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0163599A3 (en) | Pyrimidopyrimidine derivatives, processes for producing them, pharmaceutical compositions containing them and their use as anti-allergic agents | |
ES8307794A1 (es) | Un procedimiento para la preparacion de agentes antifugicos triazolicos. | |
ES8202541A1 (es) | Procedimiento para la preparacion de sulfonilureas | |
DE3167320D1 (en) | Novel uracil derivatives, process for preparing the same and a pharmaceutical composition containing the same | |
HUT52040A (en) | Process for producing diaryl-derivatives and pharmaceutical compositions containing them | |
IE872658L (en) | Tetrahydroquinoline derivatives, a process for their preparation, their use and pharmaceutical formulations containing them | |
ES8306116A1 (es) | "procedimiento para la preparacion de una sulfonilurea". | |
ES8404852A1 (es) | Procedimiento para preparar derivados de acidos isoquinolein-4-carboxilicos | |
IL106356A (en) | 4-amino-n-(4-methyl- 4-piperidinyl)- 2-methoxybenzamides, their preparation and pharmaceutical compositions containing them | |
ES8401946A1 (es) | Procedimiento para la preparacion de sulfonilureas. | |
ES8107219A1 (es) | Procedimiento para la preparacion de sulfonilureas | |
ES8704463A1 (es) | Procedimiento para preparar 2-(n-alquinil-n-fenilamino)-imidazolinas |