ES8301484A1 - Procedimiento para la obtencion de compuestos de aminohidro-xifenilo - Google Patents

Procedimiento para la obtencion de compuestos de aminohidro-xifenilo

Info

Publication number
ES8301484A1
ES8301484A1 ES504945A ES504945A ES8301484A1 ES 8301484 A1 ES8301484 A1 ES 8301484A1 ES 504945 A ES504945 A ES 504945A ES 504945 A ES504945 A ES 504945A ES 8301484 A1 ES8301484 A1 ES 8301484A1
Authority
ES
Spain
Prior art keywords
aminohydroxyphenyl
denotes hydrogen
cephalosporins
derivatives
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES504945A
Other languages
English (en)
Other versions
ES504945A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES8301484A1 publication Critical patent/ES8301484A1/es
Publication of ES504945A0 publication Critical patent/ES504945A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/59Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS DE AMINOHIDROXIFENILO, ASI COMO DE SUS HIDRATOS Y SALES, DE FORMULA (I), EN LA QUE R ES HIDROGENO O ACILO; R ES HIDROGENO O ALQUILO INFERIOR; R ES HIDROGENO O UN GRUPO DE FORMULA (R)(R )N<024>; R ES CARBOXILO PROTEGIDO O SIN PROTEGER; R ES HIDROGENO, FLUOR, CLORO O ALCOXI INFERIOR; Y N VALE 0 O 1. CONSISTE EN LA REACCION DE ACILACION DEL GRUPO 7<021>-AMINO DE UN COMPUESTO DE FORMULA (II) CON UN AGENTE DE ACILACION INTRODUCTOR DEL RESTO ACILO DE UN ACIDO CARBOXILICO DE FORMULA (III), EN LA QUE TODOS LOS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ANHIDRO INERTE, EN ATMOSFERA INERTE, A UNA TEMPERATURA ENTRE -40<025>C Y 100<025>C. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU EFICACIA ANTIBIOTICA.
ES504945A 1980-08-27 1981-08-25 Procedimiento para la obtencion de compuestos de aminohidro-xifenilo Granted ES504945A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH644680 1980-08-27

Publications (2)

Publication Number Publication Date
ES8301484A1 true ES8301484A1 (es) 1982-12-01
ES504945A0 ES504945A0 (es) 1982-12-01

Family

ID=4309766

Family Applications (2)

Application Number Title Priority Date Filing Date
ES504945A Granted ES504945A0 (es) 1980-08-27 1981-08-25 Procedimiento para la obtencion de compuestos de aminohidro-xifenilo
ES514589A Expired ES8305773A1 (es) 1980-08-27 1982-07-30 Procedimiento para la obtencion de compuestos de aminohidroxifenilo.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES514589A Expired ES8305773A1 (es) 1980-08-27 1982-07-30 Procedimiento para la obtencion de compuestos de aminohidroxifenilo.

Country Status (10)

Country Link
EP (1) EP0046734A3 (es)
JP (1) JPS5772990A (es)
AU (1) AU7463281A (es)
CA (1) CA1178270A (es)
DK (1) DK378681A (es)
ES (2) ES504945A0 (es)
FI (1) FI812605L (es)
GR (1) GR74995B (es)
NO (1) NO812893L (es)
ZA (1) ZA815911B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS601128A (ja) * 1983-06-15 1985-01-07 Shionogi & Co Ltd 作用持続型セフアクロル製剤

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL38099A (en) * 1970-12-17 1976-01-30 Smith Kline French Lab 3-heterocyclyl thiomethylcephalosporins

Also Published As

Publication number Publication date
ZA815911B (en) 1982-08-25
GR74995B (es) 1984-07-12
NO812893L (no) 1982-03-01
AU7463281A (en) 1982-03-04
DK378681A (da) 1982-02-28
CA1178270A (en) 1984-11-20
JPS5772990A (en) 1982-05-07
EP0046734A2 (de) 1982-03-03
EP0046734A3 (de) 1982-10-06
ES514589A0 (es) 1983-04-16
ES504945A0 (es) 1982-12-01
ES8305773A1 (es) 1983-04-16
FI812605L (fi) 1982-02-28

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19850909