ES476154A1 - Un procedimiento para la preparacion de nuevos derivados de cefalosporina - Google Patents
Un procedimiento para la preparacion de nuevos derivados de cefalosporinaInfo
- Publication number
- ES476154A1 ES476154A1 ES476154A ES476154A ES476154A1 ES 476154 A1 ES476154 A1 ES 476154A1 ES 476154 A ES476154 A ES 476154A ES 476154 A ES476154 A ES 476154A ES 476154 A1 ES476154 A1 ES 476154A1
- Authority
- ES
- Spain
- Prior art keywords
- cephalosporin compounds
- preparation
- treatment
- formulations containing
- bacterial infections
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere a un procedimiento para preparar antibióticos farmaceúticos de la clase de la cefalosporina. Un refuerzo considerable de la investigación se ha dirigido al desarrollo de nuevos compuestos de cefalosporina para el tratamiento de enfermedades infecciosas en el hombre. Más recientemente se ha descrito que ciertas cefalosporinas que llevan un substituyente 2-(2- aminotiazol-4-il)-2-metoxiiminoacetamido en C-7 y substituyentes que incluyen acetoximetilo, carbamoiloximetilo, (1-metil-tetrazol-5-iltio) metilo y (1-metil-tetrazol-5- iltiol) metilo y (1,3,4-tiadiazol-2-iltio)metilo en C-3 exhiben actividad contra microorganismos tanto Gram-positivos como gram-negativos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/862,318 US4200745A (en) | 1977-12-20 | 1977-12-20 | 7[2-(2-Aminothiazol-4-yl)-2-alkoxyimino]acetamido 3[4-alkyl-5-oxo-6-hydroxy-3,4 dihydro 1,2,4-triazin 3-yl]thio methyl cephalosporins |
Publications (1)
Publication Number | Publication Date |
---|---|
ES476154A1 true ES476154A1 (es) | 1980-05-16 |
Family
ID=25338200
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES476154A Expired ES476154A1 (es) | 1977-12-20 | 1978-12-19 | Un procedimiento para la preparacion de nuevos derivados de cefalosporina |
Country Status (33)
Country | Link |
---|---|
US (1) | US4200745A (es) |
EP (1) | EP0002605B1 (es) |
JP (1) | JPS5490194A (es) |
AR (1) | AR220733A1 (es) |
AT (1) | AT364189B (es) |
AU (1) | AU518484B2 (es) |
BE (1) | BE872616A (es) |
CA (1) | CA1140112A (es) |
CH (1) | CH635846A5 (es) |
CS (1) | CS204957B2 (es) |
DD (1) | DD139857A5 (es) |
DE (1) | DE2861493D1 (es) |
DK (1) | DK540278A (es) |
EG (1) | EG13666A (es) |
ES (1) | ES476154A1 (es) |
FI (1) | FI67083C (es) |
FR (1) | FR2412553A1 (es) |
GB (1) | GB2010256B (es) |
GR (1) | GR72240B (es) |
HU (1) | HU181875B (es) |
IE (1) | IE47696B1 (es) |
IL (1) | IL56166A0 (es) |
IT (1) | IT1112300B (es) |
LU (1) | LU80669A1 (es) |
MX (1) | MX5586E (es) |
NZ (1) | NZ189121A (es) |
PH (1) | PH15368A (es) |
PL (1) | PL123368B1 (es) |
PT (1) | PT68888A (es) |
RO (1) | RO75804A (es) |
SU (1) | SU793403A3 (es) |
YU (1) | YU300278A (es) |
ZA (1) | ZA787110B (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5760345B2 (es) * | 1974-12-19 | 1982-12-18 | Takeda Chemical Industries Ltd | |
MC1259A1 (fr) * | 1978-05-30 | 1980-01-14 | Hoffmann La Roche | Derives acyles |
CH641468A5 (de) * | 1978-05-30 | 1984-02-29 | Hoffmann La Roche | Cephemderivate. |
ZA806977B (en) * | 1979-11-19 | 1981-10-28 | Fujisawa Pharmaceutical Co | 7-acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof |
FI67385C (fi) * | 1979-11-21 | 1985-03-11 | Hoffmann La Roche | Foerfarande foer framstaellning av (6r 7r)-7-(2-(2-amino-4-tiazolyl)-2-(z-metoxiimino)acetamido)-3-cefem-4-karboxylsyraderivat |
US4349672A (en) * | 1979-11-29 | 1982-09-14 | Hoffmann-La Roche Inc. | Cephalosporin derivatives |
US4409387A (en) * | 1979-11-29 | 1983-10-11 | Hoffmann-La Roche Inc. | Cephalosporin derivatives |
AU536771B2 (en) * | 1980-03-25 | 1984-05-24 | F. Hoffmann-La Roche Ag | Cephalosporin derivatives |
GR75706B (es) * | 1980-06-30 | 1984-08-02 | Sanofi Sa | |
DK379581A (da) * | 1980-10-06 | 1982-04-07 | Hoffmann La Roche | Fremgangsmaade til fremstilling af acylderivater |
FR2494278A1 (fr) * | 1980-11-20 | 1982-05-21 | Rhone Poulenc Ind | Nouveaux derives de la cephalosporine, leurs preparations et les medicaments qui les contiennent |
US4698338A (en) * | 1986-02-19 | 1987-10-06 | Eli Lilly And Company | 7[2-(2-aminothiazol-4-yl)-2-benzyloximino]acetamido-3[4-alkyl-5-oxo-6-hydroxy-3,4-dihydro-1,2,4-triazin-3-yl]thiomethyl cephalosporins |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1100129A (en) * | 1974-08-02 | 1981-04-28 | William H.W. Lunn | Cephalosporin compounds |
DE2715385A1 (de) * | 1976-04-14 | 1977-11-10 | Takeda Chemical Industries Ltd | Cephalosporinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel |
NL7805715A (nl) * | 1977-06-03 | 1978-12-05 | Hoffmann La Roche | Werkwijze voor het bereiden van acylderivaten. |
-
1977
- 1977-12-20 US US05/862,318 patent/US4200745A/en not_active Expired - Lifetime
-
1978
- 1978-11-30 DK DK540278A patent/DK540278A/da not_active Application Discontinuation
- 1978-12-07 PH PH21906A patent/PH15368A/en unknown
- 1978-12-07 PT PT68888A patent/PT68888A/pt unknown
- 1978-12-07 AR AR274724A patent/AR220733A1/es active
- 1978-12-07 NZ NZ189121A patent/NZ189121A/en unknown
- 1978-12-08 BE BE1009182A patent/BE872616A/xx not_active IP Right Cessation
- 1978-12-08 FR FR7834608A patent/FR2412553A1/fr active Granted
- 1978-12-08 AU AU42347/78A patent/AU518484B2/en not_active Expired
- 1978-12-10 IL IL56166A patent/IL56166A0/xx unknown
- 1978-12-11 GR GR57837A patent/GR72240B/el unknown
- 1978-12-11 MX MX787582U patent/MX5586E/es unknown
- 1978-12-13 DE DE7878300801T patent/DE2861493D1/de not_active Expired
- 1978-12-13 GB GB7848211A patent/GB2010256B/en not_active Expired
- 1978-12-13 SU SU782699098A patent/SU793403A3/ru active
- 1978-12-13 EP EP78300801A patent/EP0002605B1/en not_active Expired
- 1978-12-13 CA CA000317875A patent/CA1140112A/en not_active Expired
- 1978-12-14 FI FI783846A patent/FI67083C/fi not_active IP Right Cessation
- 1978-12-18 JP JP15810078A patent/JPS5490194A/ja active Pending
- 1978-12-18 LU LU80669A patent/LU80669A1/xx unknown
- 1978-12-18 CS CS788518A patent/CS204957B2/cs unknown
- 1978-12-19 HU HU78EI830A patent/HU181875B/hu unknown
- 1978-12-19 CH CH1295478A patent/CH635846A5/fr not_active IP Right Cessation
- 1978-12-19 AT AT0908378A patent/AT364189B/de not_active IP Right Cessation
- 1978-12-19 IE IE2502/78A patent/IE47696B1/en unknown
- 1978-12-19 EG EG712/78A patent/EG13666A/xx active
- 1978-12-19 IT IT31016/78A patent/IT1112300B/it active
- 1978-12-19 ES ES476154A patent/ES476154A1/es not_active Expired
- 1978-12-19 RO RO7895973A patent/RO75804A/ro unknown
- 1978-12-19 ZA ZA787110A patent/ZA787110B/xx unknown
- 1978-12-20 DD DD78209940A patent/DD139857A5/de unknown
- 1978-12-20 PL PL1978211973A patent/PL123368B1/pl unknown
- 1978-12-20 YU YU03002/78A patent/YU300278A/xx unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20000301 |