ES8203882A1 - Un procedimiento para la preparacion de 1-(8-quinole- il)-2-pirrolidinona y sus sales de adicion de acido - Google Patents
Un procedimiento para la preparacion de 1-(8-quinole- il)-2-pirrolidinona y sus sales de adicion de acidoInfo
- Publication number
- ES8203882A1 ES8203882A1 ES497242A ES497242A ES8203882A1 ES 8203882 A1 ES8203882 A1 ES 8203882A1 ES 497242 A ES497242 A ES 497242A ES 497242 A ES497242 A ES 497242A ES 8203882 A1 ES8203882 A1 ES 8203882A1
- Authority
- ES
- Spain
- Prior art keywords
- formulations
- medicine
- compound
- synthesis
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/40—Nitrogen atoms attached in position 8
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Catalysts (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE 1-(8-QUINOLEIL)-2-PIRROLIDINONA DE SUS SALES DE ADICION DE ACIDO. CONSISTE EN CICLISAR UN COMPUESTO (I) O (II) EN PRESENCIA DE UN CATALIZADOR QUE SEA O INCLUYA UN HIDRURO, HIDROXIDO O ALCOXIDO DE METAL ALCALINO, HIDRURO DE POTASIO, HIDROXIDO DE POTASIO O TERC-BUTOXIDO DE POTASIO. EL DICHO CATALIZADOR ES DE TRANSFERENCIA DE FASES, SIENDO CLORURO DE TRIETILBENCILAMONIO. SE OBTIENE EL COMPUESTO (III).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7941409 | 1979-11-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8203882A1 true ES8203882A1 (es) | 1982-04-01 |
ES497242A0 ES497242A0 (es) | 1982-04-01 |
Family
ID=10509524
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES497242A Granted ES497242A0 (es) | 1979-11-30 | 1980-11-28 | Un procedimiento para la preparacion de 1-(8-quinole- il)-2-pirrolidinona y sus sales de adicion de acido |
Country Status (18)
Country | Link |
---|---|
US (1) | US4366158A (es) |
EP (1) | EP0030023A3 (es) |
JP (1) | JPS5699475A (es) |
KR (1) | KR830004293A (es) |
AR (1) | AR228442A1 (es) |
AT (1) | AT375363B (es) |
AU (1) | AU6495080A (es) |
CA (1) | CA1156235A (es) |
DK (1) | DK506480A (es) |
ES (1) | ES497242A0 (es) |
FI (1) | FI803704L (es) |
GB (1) | GB2063868B (es) |
GR (1) | GR71918B (es) |
HU (1) | HU185224B (es) |
IL (1) | IL61580A (es) |
IT (1) | IT1221040B (es) |
NZ (1) | NZ195688A (es) |
ZA (1) | ZA807467B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE602004000260T2 (de) | 2003-07-22 | 2006-08-24 | Arena Pharmaceuticals, Inc., San Diego | Diaryl- und arylheteroarylharnstoffderivate als modulatoren des 5-ht2a-serotoninrezeptors, die sich zur prophylaxe und behandlung von damit im zusammenhang stehenden erkrankungen eignen |
GB0507198D0 (en) * | 2005-04-08 | 2005-05-18 | Sb Pharmco Inc | Process for preparing bicyclic compounds |
GB0519758D0 (en) * | 2005-09-28 | 2005-11-09 | Glaxo Group Ltd | Novel process |
WO2009074607A1 (en) | 2007-12-12 | 2009-06-18 | Glaxo Group Limited | Combinations comprising 3-phenylsulfonyl-8-piperazinyl-1yl-quinoline |
WO2009123714A2 (en) | 2008-04-02 | 2009-10-08 | Arena Pharmaceuticals, Inc. | Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor |
WO2010062321A1 (en) | 2008-10-28 | 2010-06-03 | Arena Pharmaceuticals, Inc. | Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2h-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)-urea and crystalline forms related thereto |
CN109562085A (zh) | 2015-06-12 | 2019-04-02 | 阿速万科学有限责任公司 | 用于预防和治疗rem睡眠行为障碍的二芳基和芳基杂芳基脲衍生物 |
BR112018000728A2 (pt) | 2015-07-15 | 2018-09-04 | Axovant Sciences Gmbh | resumo método para a profilaxia e/ou tratamento de alucinações visuais em um sujeito com necessidade do mesmo |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4143151A (en) * | 1978-07-03 | 1979-03-06 | The Dow Chemical Company | Method for treating hyperglycemia in mammals using arylamino benzoic acids |
-
1980
- 1980-11-24 US US06/209,426 patent/US4366158A/en not_active Expired - Lifetime
- 1980-11-26 GB GB8037872A patent/GB2063868B/en not_active Expired
- 1980-11-28 HU HU802850A patent/HU185224B/hu unknown
- 1980-11-28 DK DK506480A patent/DK506480A/da not_active Application Discontinuation
- 1980-11-28 KR KR1019800004552A patent/KR830004293A/ko unknown
- 1980-11-28 FI FI803704A patent/FI803704L/fi not_active Application Discontinuation
- 1980-11-28 NZ NZ195688A patent/NZ195688A/en unknown
- 1980-11-28 IL IL61580A patent/IL61580A/xx unknown
- 1980-11-28 CA CA000365722A patent/CA1156235A/en not_active Expired
- 1980-11-28 AT AT0582780A patent/AT375363B/de not_active IP Right Cessation
- 1980-11-28 AR AR283420A patent/AR228442A1/es active
- 1980-11-28 GR GR63493A patent/GR71918B/el unknown
- 1980-11-28 JP JP16791880A patent/JPS5699475A/ja active Pending
- 1980-11-28 EP EP80107463A patent/EP0030023A3/en not_active Ceased
- 1980-11-28 AU AU64950/80A patent/AU6495080A/en not_active Abandoned
- 1980-11-28 ZA ZA00807467A patent/ZA807467B/xx unknown
- 1980-11-28 ES ES497242A patent/ES497242A0/es active Granted
- 1980-11-28 IT IT50277/80A patent/IT1221040B/it active
Also Published As
Publication number | Publication date |
---|---|
AU6495080A (en) | 1981-06-04 |
HU185224B (en) | 1984-12-28 |
DK506480A (da) | 1981-05-31 |
JPS5699475A (en) | 1981-08-10 |
EP0030023A3 (en) | 1981-09-02 |
NZ195688A (en) | 1984-09-28 |
GB2063868A (en) | 1981-06-10 |
CA1156235A (en) | 1983-11-01 |
ATA582780A (de) | 1983-12-15 |
EP0030023A2 (en) | 1981-06-10 |
FI803704L (fi) | 1981-05-31 |
GR71918B (es) | 1983-08-17 |
IL61580A (en) | 1984-06-29 |
ES497242A0 (es) | 1982-04-01 |
AR228442A1 (es) | 1983-03-15 |
IT1221040B (it) | 1990-06-21 |
IL61580A0 (en) | 1980-12-31 |
IT8050277A0 (it) | 1980-11-28 |
KR830004293A (ko) | 1983-07-09 |
US4366158A (en) | 1982-12-28 |
GB2063868B (en) | 1984-02-29 |
ZA807467B (en) | 1982-07-28 |
AT375363B (de) | 1984-07-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20010301 |